Author results

1BKD
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COMPLEX OF HUMAN H-RAS WITH HUMAN SOS-1
Descriptor:H-RAS, SON OF SEVENLESS-1
Authors:Boriack-Sjodin, P.A., Margarit, S.M., Sagi, D.B., Kuriyan, J.
Deposit date:1998-07-06
Release date:1999-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The structural basis of the activation of Ras by Sos.
Nature, 394, 1998
1BN1
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CARBONIC ANHYDRASE II INHIBITOR
Descriptor:CARBONIC ANHYDRASE, MERCURY (II) ION, ZINC ION, ...
Authors:Boriack-Sjodin, P.A., Zeitlin, S., Christianson, D.W.
Deposit date:1998-07-31
Release date:1999-05-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural analysis of inhibitor binding to human carbonic anhydrase II.
Protein Sci., 7, 1998
1BN3
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CARBONIC ANHYDRASE II INHIBITOR
Descriptor:CARBONIC ANHYDRASE, MERCURY (II) ION, ZINC ION, ...
Authors:Boriack-Sjodin, P.A., Zeitlin, S., Christianson, D.W.
Deposit date:1998-07-31
Release date:1999-05-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural analysis of inhibitor binding to human carbonic anhydrase II.
Protein Sci., 7, 1998
1BN4
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CARBONIC ANHYDRASE II INHIBITOR
Descriptor:CARBONIC ANHYDRASE, MERCURY (II) ION, ZINC ION, ...
Authors:Boriack-Sjodin, P.A., Zeitlin, S., Christianson, D.W.
Deposit date:1998-07-31
Release date:1999-05-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural analysis of inhibitor binding to human carbonic anhydrase II.
Protein Sci., 7, 1998
1BNM
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CARBONIC ANHYDRASE II INHIBITOR
Descriptor:CARBONIC ANHYDRASE, MERCURY (II) ION, ZINC ION, ...
Authors:Boriack-Sjodin, P.A., Zeitlin, S., Christianson, D.W.
Deposit date:1998-07-30
Release date:1999-05-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural analysis of inhibitor binding to human carbonic anhydrase II.
Protein Sci., 7, 1998
1BNN
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CARBONIC ANHYDRASE II INHIBITOR
Descriptor:CARBONIC ANHYDRASE, MERCURY (II) ION, ZINC ION, ...
Authors:Boriack-Sjodin, P.A., Zeitlin, S., Christianson, D.W.
Deposit date:1998-07-30
Release date:1999-05-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural analysis of inhibitor binding to human carbonic anhydrase II.
Protein Sci., 7, 1998
1BNQ
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CARBONIC ANHYDRASE II INHIBITOR
Descriptor:CARBONIC ANHYDRASE, MERCURY (II) ION, ZINC ION, ...
Authors:Boriack-Sjodin, P.A., Zeitlin, S., Christianson, D.W.
Deposit date:1998-07-30
Release date:1999-06-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural analysis of inhibitor binding to human carbonic anhydrase II.
Protein Sci., 7, 1998
1BNT
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CARBONIC ANHYDRASE II INHIBITOR
Descriptor:CARBONIC ANHYDRASE, MERCURY (II) ION, ZINC ION, ...
Authors:Boriack-Sjodin, P.A., Zeitlin, S., Christianson, D.W.
Deposit date:1998-07-30
Release date:1999-06-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural analysis of inhibitor binding to human carbonic anhydrase II.
Protein Sci., 7, 1998
1BNU
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CARBONIC ANHYDRASE II INHIBITOR
Descriptor:CARBONIC ANHYDRASE, MERCURY (II) ION, ZINC ION, ...
Authors:Boriack-Sjodin, P.A., Zeitlin, S., Christianson, D.W.
Deposit date:1998-07-30
Release date:1999-06-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural analysis of inhibitor binding to human carbonic anhydrase II.
Protein Sci., 7, 1998
1BNV
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CARBONIC ANHYDRASE II INHIBITOR
Descriptor:CARBONIC ANHYDRASE, MERCURY (II) ION, ZINC ION, ...
Authors:Boriack-Sjodin, P.A., Zeitlin, S., Christianson, D.W.
Deposit date:1998-07-30
Release date:1999-02-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural analysis of inhibitor binding to human carbonic anhydrase II.
Protein Sci., 7, 1998
1BNW
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CARBONIC ANHYDRASE II INHIBITOR
Descriptor:CARBONIC ANHYDRASE, MERCURY (II) ION, ZINC ION, ...
Authors:Boriack-Sjodin, P.A., Zeitlin, S., Christianson, D.W.
Deposit date:1998-07-30
Release date:1999-06-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural analysis of inhibitor binding to human carbonic anhydrase II.
Protein Sci., 7, 1998
1DMX
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MURINE MITOCHONDRIAL CARBONIC ANYHDRASE V AT 2.45 ANGSTROMS RESOLUTION
Descriptor:MURINE CARBONIC ANHYDRASE V, ZINC ION
Authors:Boriack-Sjodin, P.A., Christianson, D.W.
Deposit date:1995-10-04
Release date:1996-04-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structure determination of murine mitochondrial carbonic anhydrase V at 2.45-A resolution: implications for catalytic proton transfer and inhibitor design.
Proc.Natl.Acad.Sci.USA, 92, 1995
1DMY
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COMPLEX BETWEEN MURINE MITOCHONDRIAL CARBONIC ANYHDRASE V AND THE TRANSITION STATE ANALOGUE ACETAZOLAMIDE
Descriptor:MURINE CARBONIC ANHYDRASE V, ZINC ION, 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE
Authors:Boriack-Sjodin, P.A., Christianson, D.W.
Deposit date:1995-10-04
Release date:1996-04-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structure determination of murine mitochondrial carbonic anhydrase V at 2.45-A resolution: implications for catalytic proton transfer and inhibitor design.
Proc.Natl.Acad.Sci.USA, 92, 1995
5C9Z
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CRYSTAL STRUCTURE OF PRMT5:MEP50 WITH EPZ015866 AND SINEFUNGIN
Descriptor:Protein arginine N-methyltransferase 5, Methylosome protein 50, SINEFUNGIN, ...
Authors:Boriack-Sjodin, P.A.
Deposit date:2015-06-29
Release date:2016-06-29
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:Crystal structure of PRMT5/MEP50 complex with sinefungin and 15866
To Be Published
5DWQ
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CRYSTAL STRUCTURE OF CARM1, SINEFUNGIN, AND METHYLATED H3 PEPTIDE (R17)
Descriptor:Histone-arginine methyltransferase CARM1, methylated H3 peptide, SINEFUNGIN, ...
Authors:Boriack-Sjodin, P.A.
Deposit date:2015-09-22
Release date:2015-11-25
Last modified:2016-03-30
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:Structural Insights into Ternary Complex Formation of Human CARM1 with Various Substrates.
Acs Chem.Biol., 11, 2016
5DX0
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CRYSTAL STRUCTURE OF CARM1, SINEFUNGIN, AND H3 PEPTIDE (R17)
Descriptor:Histone-arginine methyltransferase CARM1, H3 peptide, SINEFUNGIN, ...
Authors:Boriack-Sjodin, P.A.
Deposit date:2015-09-23
Release date:2015-11-25
Last modified:2016-03-30
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural Insights into Ternary Complex Formation of Human CARM1 with Various Substrates.
Acs Chem.Biol., 11, 2016
5DX1
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CRYSTAL STRUCTURE OF CARM1, SINEFUNGIN, AND PABP1 PEPTIDE (R455)
Descriptor:Histone-arginine methyltransferase CARM1, PABP1 peptide, SINEFUNGIN, ...
Authors:Boriack-Sjodin, P.A.
Deposit date:2015-09-23
Release date:2015-11-25
Last modified:2016-03-30
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Structural Insights into Ternary Complex Formation of Human CARM1 with Various Substrates.
Acs Chem.Biol., 11, 2016
5DX8
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CRYSTAL STRUCTURE OF CARM1, SINEFUNGIN, AND METHYLATED PABP1 PEPTIDE (R455)
Descriptor:Histone-arginine methyltransferase CARM1, methylated PABP1 peptide, SINEFUNGIN
Authors:Boriack-Sjodin, P.A.
Deposit date:2015-09-23
Release date:2015-11-25
Last modified:2016-03-30
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Structural Insights into Ternary Complex Formation of Human CARM1 with Various Substrates.
Acs Chem.Biol., 11, 2016
5DXA
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CRYSTAL STRUCTURE OF CARM1, SINEFUNGIN, AND METHYLATED PABP1 PEPTIDE (R460)
Descriptor:Histone-arginine methyltransferase CARM1, methylated PABP1 peptide, SINEFUNGIN, ...
Authors:Boriack-Sjodin, P.A.
Deposit date:2015-09-23
Release date:2015-11-25
Last modified:2016-03-30
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Structural Insights into Ternary Complex Formation of Human CARM1 with Various Substrates.
Acs Chem.Biol., 11, 2016
5DXJ
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CRYSTAL STRUCTURE OF CARM1 AND SINEFUNGIN
Descriptor:Histone-arginine methyltransferase CARM1, SINEFUNGIN, GLYCEROL
Authors:Boriack-Sjodin, P.A.
Deposit date:2015-09-23
Release date:2015-11-25
Last modified:2016-03-30
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural Insights into Ternary Complex Formation of Human CARM1 with Various Substrates.
Acs Chem.Biol., 11, 2016
1A42
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HUMAN CARBONIC ANHYDRASE II COMPLEXED WITH BRINZOLAMIDE
Descriptor:CARBONIC ANHYDRASE II, MERCURY (II) ION, ZINC ION, ...
Authors:Boriack-Sjodin, P.A., Christianson, D.W.
Deposit date:1998-02-10
Release date:1999-03-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structures of murine carbonic anhydrase IV and human carbonic anhydrase II complexed with brinzolamide: molecular basis of isozyme-drug discrimination.
Protein Sci., 7, 1998
1URT
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MURINE CARBONIC ANHYDRASE V
Descriptor:CARBONIC ANHYDRASE V, ZINC ION
Authors:Boriack-Sjodin, P.A., Christianson, D.W.
Deposit date:1996-07-03
Release date:1997-01-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure-based design of an intramolecular proton transfer site in murine carbonic anhydrase V.
Biochemistry, 35, 1996
2BDN
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CRYSTAL STRUCTURE OF HUMAN MCP-1 BOUND TO A BLOCKING ANTIBODY, 11K2
Descriptor:Small inducible cytokine A2, Antibody light chain 11K2, Antibody heavy chain 11K2
Authors:Boriack-Sjodin, P.A., Rushe, M., Reid, C., Jarpe, M., van Vlijmen, H., Bailly, V.
Deposit date:2005-10-20
Release date:2006-06-13
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.53 Å)
Cite:Structure activity relationships of monocyte chemoattractant proteins in complex with a blocking antibody.
Protein Eng.Des.Sel., 19, 2006
3EOT
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CRYSTAL STRUCTURE OF LAC031, AN ENGINEERED ANTI-VLA1 FAB
Descriptor:FAB FRAGMENT, HEAVY CHAIN, LIGHT CHAIN
Authors:Boriack-Sjodin, P.A., Clark, L.A.
Deposit date:2008-09-29
Release date:2009-01-20
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:An antibody loop replacement design feasibility study and a loop-swapped dimer structure.
Protein Eng.Des.Sel., 22, 2009
3FAA
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CRYSTAL STRUCTURE OF TGFBRI COMPLEXED WITH A 2-AMINOIMIDAZOLE INHIBITOR
Descriptor:TGF-beta receptor type-1, N-[4-(5-fluoro-6-methylpyridin-2-yl)-5-quinoxalin-6-yl-1H-imidazol-2-yl]acetamide, PHOSPHATE ION
Authors:Boriack-Sjodin, P.A., Fitch, C.
Deposit date:2008-11-16
Release date:2009-01-27
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:2-Aminoimidazoles inhibitors of TGF-beta receptor 1.
Bioorg.Med.Chem.Lett., 19, 2009