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1A45
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GAMMAF CRYSTALLIN FROM BOVINE LENS
Descriptor:GAMMAF CRYSTALLIN
Authors:Norledge, B.V., Hay, R., Bateman, O.A., Slingsby, C., White, H.E., Moss, D.S., Lindley, P.F., Driessen, H.P.C.
Deposit date:1998-02-10
Release date:1998-06-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Towards a molecular understanding of phase separation in the lens: a comparison of the X-ray structures of two high Tc gamma-crystallins, gammaE and gammaF, with two low Tc gamma-crystallins, gammaB and gammaD.
Exp.Eye Res., 65, 1997
1A5D
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GAMMAE CRYSTALLIN FROM RAT LENS
Descriptor:GAMMAE CRYSTALLIN
Authors:Norledge, B.V., Hay, R., Bateman, O.A., Slingsby, C., Driessen, H.P.C.
Deposit date:1998-02-12
Release date:1998-05-27
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Towards a molecular understanding of phase separation in the lens: a comparison of the X-ray structures of two high Tc gamma-crystallins, gammaE and gammaF, with two low Tc gamma-crystallins, gammaB and gammaD.
Exp.Eye Res., 65, 1997
1DSL
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GAMMA B CRYSTALLIN C-TERMINAL DOMAIN
Descriptor:GAMMA B CRYSTALLIN
Authors:Norledge, B.V., Mayr, E.-M., Glockshuber, R., Bateman, O.A., Slingsby, C., Jaenicke, R., Driessen, H.P.C.
Deposit date:1996-02-01
Release date:1996-07-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:The X-ray structures of two mutant crystallin domains shed light on the evolution of multi-domain proteins.
Nat.Struct.Biol., 3, 1996
1E7N
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THE N-TERMINAL DOMAIN OF BETA-B2-CRYSTALLIN RESEMBLES THE PUTATIVE ANCESTRAL HOMODIMER
Descriptor:BETA-CRYSTALLIN B2
Authors:Clout, N.J., Basak, A., Wieligmann, K., Bateman, O.A., Jaenicke, R., Slingsby, C.
Deposit date:2000-08-31
Release date:2000-10-05
Last modified:2018-05-30
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:The N-Terminal Domain of Betab2-Crystallin Resembles the Putative Ancestral Homodimer.
J.Mol.Biol., 304, 2000
1GAM
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GAMMA B CRYSTALLIN TRUNCATED C-TERMINAL DOMAIN
Descriptor:GAMMA B CRYSTALLIN
Authors:Norledge, B.V., Mayr, E.-M., Glockshuber, R., Bateman, O.A., Slingsby, C., Jaenicke, R., Driessen, H.P.C.
Deposit date:1996-02-02
Release date:1996-07-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The X-ray structures of two mutant crystallin domains shed light on the evolution of multi-domain proteins.
Nat.Struct.Biol., 3, 1996
1HA4
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GAMMAS CRYSTALLIN C TERMINAL DOMAIN FROM HOMO SAPIENS
Descriptor:GAMMA CRYSTALLIN S
Authors:Purkiss, A.G., Slingsby, C., Bateman, O.A., Goodfellow, J.M.
Deposit date:2001-03-27
Release date:2001-11-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The X-Ray Crystal Structure of Human Gamma S-Crystallin C-Terminal Domain
J.Biol.Chem., 277, 2002
1OKI
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CRYSTAL STRUCTURE OF TRUNCATED HUMAN BETA-B1-CRYSTALLIN
Descriptor:BETA CRYSTALLIN B1
Authors:van Montfort, R.L.M., Bateman, O.A., Lubsen, N.H., Slingsby, C.
Deposit date:2003-07-25
Release date:2004-01-22
Last modified:2018-03-28
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal Structure of Truncated Human Beta-B1-Crystallin
Protein Sci., 12, 2003
1YTQ
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STRUCTURE OF NATIVE HUMAN BETA B2 CRYSTALLIN
Descriptor:Beta crystallin B2
Authors:Slingsby, C., Smith, M.A., Bateman, O.A.
Deposit date:2005-02-10
Release date:2006-01-31
Last modified:2013-06-26
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Mutation of interfaces in domain-swapped human betaB2-crystallin
Protein Sci., 16, 2007
2BV2
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BETA GAMMA CRYSTALLIN FROM CIONA INTESTINALIS
Descriptor:CIONA BETAGAMMA-CRYSTALLIN, CALCIUM ION, ACETATE ION, ...
Authors:Shimeld, S.M., Purkiss, A.G., Dirks, R.P.H., Bateman, O.A., Slingsby, C., Lubsen, N.H.
Deposit date:2005-06-21
Release date:2005-09-29
Last modified:2017-07-12
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Urochordate Betagamma-Crystallin and the Evolutionary Origin of the Vertebrate Eye Lens.
Curr.Biol., 15, 2005
2J9I
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LENGSIN IS A SURVIVOR OF AN ANCIENT FAMILY OF CLASS I GLUTAMINE SYNTHETASES IN EUKARYOTES THAT HAS UNDERGONE EVOLUTIONARY RE- ENGINEERING FOR A TISSUE-SPECIFIC ROLE IN THE VERTEBRATE EYE LENS.
Descriptor:GLUTAMATE-AMMONIA LIGASE DOMAIN-CONTAINING PROTEIN 1
Authors:Wyatt, K., White, H.E., Wang, L., Bateman, O.A., Slingsby, C., Orlova, E.V., Wistow, G.
Deposit date:2006-11-09
Release date:2006-12-13
Last modified:2017-08-23
Method:ELECTRON MICROSCOPY (17 Å)
Cite:Lengsin is a Survivor of an Ancient Family of Class I Glutamine Synthetases Re-Engineered by Evolution for a Role in the Vertebrate Lens.
Structure, 14, 2006
2V2U
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STRUCTURE OF MOUSE GAMMAC-CRYSTALLIN
Descriptor:GAMMA CRYSTALLIN C
Authors:Purkiss, A.G., Bateman, O.A., Wyatt, K., David, L.L., Wistow, G.J., Slingsby, C.
Deposit date:2007-06-07
Release date:2007-06-19
Last modified:2013-12-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Evolutionary Adaptation of Human and Mouse Eye Lens Gammac-Crystallins for Solubility and Stability: Fine-Tuning of Molecular Dipoles.
J.Mol.Biol., 372, 2007
2WJ5
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RAT ALPHA CRYSTALLIN DOMAIN
Descriptor:HEAT SHOCK PROTEIN BETA-6
Authors:Naylor, C.E., Bagneris, C., Bateman, O.A., Cronin, N., Keep, N.H., Slingsby, C.
Deposit date:2009-05-22
Release date:2009-08-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.12 Å)
Cite:Crystal Structures of Alpha-Crystallin Domain Dimers of Alphab-Crystallin and Hsp20.
J.Mol.Biol., 392, 2009
2WJ7
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HUMAN ALPHAB CRYSTALLIN
Descriptor:ALPHA-CRYSTALLIN B CHAIN
Authors:Naylor, C.E., Bagneris, C., Bateman, O.A., Cronin, N., Keep, N.H., Slingsby, C.
Deposit date:2009-05-22
Release date:2009-08-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.631 Å)
Cite:Crystal Structures of Alpha-Crystallin Domain Dimers of Alphab-Crystallin and Hsp20.
J.Mol.Biol., 392, 2009
1O9J
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THE X-RAY CRYSTAL STRUCTURE OF ETA-CRYSTALLIN
Descriptor:ALDEHYDE DEHYDROGENASE, CYTOSOLIC 1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:Purkiss, A.G., Van Montfort, R., Wistow, G., Slingsby, C.
Deposit date:2002-12-15
Release date:2003-04-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structure of Eta-Crystallin: Adaptation of a Class 1 Aldehyde Dehydrogenase for a New Role in the Eye Lens
Biochemistry, 42, 2003
2Y1Y
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HUMAN ALPHAB CRYSTALLIN ACD(RESIDUES 71-157)
Descriptor:ALPHA-CRYSTALLIN B CHAIN,, (4R)-2-METHYLPENTANE-2,4-DIOL
Authors:Naylor, C.E., Bagneris, C., Clark, A.R., Keep, N.H., Slingsby, C.
Deposit date:2010-12-10
Release date:2011-03-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of R120G Disease Mutant of Human Alphab-Crystallin Domain Dimer Shows Closure of a Groove
J.Mol.Biol., 408, 2011
2Y1Z
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HUMAN ALPHAB CRYSTALLIN ACD R120G
Descriptor:ALPHA-CRYSTALLIN B CHAIN, (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL
Authors:Clark, A.R., Bagneris, C., Naylor, C.E., Keep, N.H., Slingsby, C.
Deposit date:2010-12-10
Release date:2011-03-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure of R120G Disease Mutant of Human Alphab-Crystallin Domain Dimer Shows Closure of a Groove
J.Mol.Biol., 408, 2011
2Y22
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HUMAN ALPHAB-CRYSTALLIN DOMAIN (RESIDUES 67-157)
Descriptor:ALPHA-CRYSTALLIN B
Authors:Naylor, C.E., Bagneris, C., Clark, A.R., Keep, N.H., Slingsby, C.
Deposit date:2010-12-13
Release date:2011-03-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Crystal Structure of R120G Disease Mutant of Human Alphab-Crystallin Domain Dimer Shows Closure of a Groove
J.Mol.Biol., 408, 2011