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2C53
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A COMPARATIVE STUDY OF URACIL DNA GLYCOSYLASES FROM HUMAN AND HERPES SIMPLEX VIRUS TYPE 1
Descriptor:URACIL DNA GLYCOSYLASE, 2'-DEOXYURIDINE, GLYCEROL
Authors:Krusong, K., Carpenter, E.P., Bellmy, S.R.W., Savva, R., Baldwin, G.S.
Deposit date:2005-10-25
Release date:2005-11-28
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A Comparative Study of Uracil-DNA Glycosylases from Human and Herpes Simplex Virus Type 1.
J.Biol.Chem., 281, 2006
2C56
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A COMPARATIVE STUDY OF URACIL DNA GLYCOSYLASES FROM HUMAN AND HERPES SIMPLEX VIRUS TYPE 1
Descriptor:URACIL DNA GLYCOSYLASE, SUCROSE
Authors:Krusong, K., Carpenter, E.P., Bellamy, S.R.W., Savva, R., Baldwin, G.S.
Deposit date:2005-10-26
Release date:2005-11-28
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A Comparative Study of Uracil-DNA Glycosylases from Human and Herpes Simplex Virus Type 1.
J.Biol.Chem., 281, 2006
2JC5
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APURINIC APYRIMIDINIC (AP) ENDONUCLEASE (NAPE) FROM NEISSERIA MENINGITIDIS
Descriptor:EXODEOXYRIBONUCLEASE, MAGNESIUM ION, BICINE, ...
Authors:Carpenter, E.P., Corbett, A., Thomson, H., Adacha, J., Jensen, K., Bergeron, J., Kasampalidis, I., Exley, R., Winterbotham, M., Tang, C., Baldwin, G.S., Freemont, P.
Deposit date:2006-12-19
Release date:2007-03-06
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Ap Endonuclease Paralogues with Distinct Activities in DNA Repair and Bacterial Pathogenesis.
Embo J., 26, 2007
4B5F
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SUBSTRATE BOUND NEISSERIA AP ENDONUCLEASE IN ABSENCE OF METAL IONS (CRYSTAL FORM 1)
Descriptor:PUTATIVE EXODEOXYRIBONUCLEASE, 5'-D(*GP*CP*TP*AP*CP*3DRP*GP*AP*TP*CP*GP)-3', 5'-D(*CP*GP*AP*TP*CP*GP*GP*TP*AP*GP*CP)-3'
Authors:Lu, D., Silhan, J., MacDonald, J.T., Carpenter, E.P., Jensen, K., Tang, C.M., Baldwin, G.S., Freemont, P.S.
Deposit date:2012-08-03
Release date:2012-10-17
Last modified:2018-02-28
Method:X-RAY DIFFRACTION (2.005 Å)
Cite:Structural basis for the recognition and cleavage of abasic DNA in Neisseria meningitidis.
Proc. Natl. Acad. Sci. U.S.A., 109, 2012
4B5G
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SUBSTRATE BOUND NEISSERIA AP ENDONUCLEASE IN ABSENCE OF METAL IONS (CRYSTAL FORM 2)
Descriptor:EXODEOXYRIBONUCLEASE, 5'-D(*GP*CP*TP*AP*CP*(3DR)P*CP*AP*TP*CP*GP)-3', 5'-D(*CP*GP*AP*TP*GP*GP*GP*TP*AP*GP*CP)-3'
Authors:Lu, D., Silhan, J., MacDonald, J.T., Carpenter, E.P., Jensen, K., Tang, C.M., Baldwin, G.S., Freemont, P.S.
Deposit date:2012-08-03
Release date:2012-10-17
Last modified:2018-02-28
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structural basis for the recognition and cleavage of abasic DNA in Neisseria meningitidis.
Proc. Natl. Acad. Sci. U.S.A., 109, 2012
4B5H
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SUBSTATE BOUND INACTIVE MUTANT OF NEISSERIA AP ENDONUCLEASE IN PRESENCE OF METAL IONS
Descriptor:PUTATIVE EXODEOXYRIBONUCLEASE, 5'-D(*GP*CP*TP*AP*CP*3DRP*CP*AP*TP*CP*GP)-3', 5'-D(*CP*GP*AP*TP*GP*GP*GP*TP*AP*GP*CP)-3', ...
Authors:Lu, D., Silhan, J., MacDonald, J.T., Carpenter, E.P., Jensen, K., Tang, C.M., Baldwin, G.S., Freemont, P.S.
Deposit date:2012-08-03
Release date:2012-10-17
Last modified:2018-02-28
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Structural basis for the recognition and cleavage of abasic DNA in Neisseria meningitidis.
Proc. Natl. Acad. Sci. U.S.A., 109, 2012
4B5I
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PRODUCT COMPLEX OF NEISSERIA AP ENDONUCLEASE IN PRESENCE OF METAL IONS
Descriptor:PUTATIVE EXODEOXYRIBONUCLEASE, 5'-D(*GP*CP*TP*AP*CP)-3', 5'-D(*CP*GP*AP*TP*GP*GP*GP*TP*AP*GP*CP)-3', ...
Authors:Lu, D., Silhan, J., MacDonald, J.T., Carpenter, E.P., Jensen, K., Tang, C.M., Baldwin, G.S., Freemont, P.S.
Deposit date:2012-08-03
Release date:2012-10-17
Last modified:2018-02-28
Method:X-RAY DIFFRACTION (2.555 Å)
Cite:Structural basis for the recognition and cleavage of abasic DNA in Neisseria meningitidis.
Proc. Natl. Acad. Sci. U.S.A., 109, 2012
4B5J
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NEISSERIA AP ENDONUCLEASE BOUND TO THE SUBSTRATE WITH AN ORPHAN ADENINE BASE
Descriptor:PUTATIVE EXODEOXYRIBONUCLEASE, 5'-D(*GP*CP*TP*AP*CP*(3DR)P*CP*AP*TP*CP*GP)-3', 5'-D(*CP*GP*AP*TP*GP*AP*GP*TP*AP*GP*CP)-3'
Authors:Lu, D., Silhan, J., MacDonald, J.T., Carpenter, E.P., Jensen, K., Tang, C.M., Baldwin, G.S., Freemont, P.S.
Deposit date:2012-08-03
Release date:2012-10-17
Last modified:2018-02-28
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis for the recognition and cleavage of abasic DNA in Neisseria meningitidis.
Proc. Natl. Acad. Sci. U.S.A., 109, 2012
4B5M
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NEISSERIA AP ENDONUCLEASE BOUND TO THE SUBSTRATE WITH A CYTOSINE ORPHAN BASE
Descriptor:PUTATIVE EXODEOXYRIBONUCLEASE, 5'-D(*3DRP*CP*AP*TP*CP*GP)-3', 5'-D(*GP*CP*TP*AP*CP)-3', ...
Authors:Lu, D., Silhan, J., MacDonald, J.T., Carpenter, E.P., Jensen, K., Tang, C.M., Baldwin, G.S., Freemont, P.S.
Deposit date:2012-08-06
Release date:2012-10-17
Last modified:2018-02-28
Method:X-RAY DIFFRACTION (2.758 Å)
Cite:Structural basis for the recognition and cleavage of abasic DNA in Neisseria meningitidis.
Proc. Natl. Acad. Sci. U.S.A., 109, 2012
6FK4
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STRUCTURE OF 3' PHOSPHATASE NEXO (WT) FROM NEISSERIA BOUND TO DNA SUBSTRATE
Descriptor:Exodeoxyribonuclease III, DNA (5'-D(P*GP*CP*TP*AP*GP*CP*GP*AP*AP*GP*CP*TP*AP*GP*A)-3'), (4S)-2-METHYL-2,4-PENTANEDIOL
Authors:Silhan, J., Zhao, Q., Boura, E., Thomson, H., Foster, A., Tang, C.M., Freemont, P.S., Baldwin, G.S.
Deposit date:2018-01-23
Release date:2018-10-31
Last modified:2018-12-26
Method:X-RAY DIFFRACTION (2.297 Å)
Cite:Structural basis for recognition and repair of the 3'-phosphate by NExo, a base excision DNA repair nuclease from Neisseria meningitidis.
Nucleic Acids Res., 46, 2018
6FK5
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STRUCTURE OF 3' PHOSPHATASE NEXO (D146N) FROM NEISSERIA BOUND TO DNA SUBSTRATE IN PRESENCE OF MAGNESIUM ION
Descriptor:NExo D146N, DNA (5'-D(P*CP*TP*AP*GP*CP*GP*AP*AP*GP*CP*TP*AP*GP*A)-3'), MAGNESIUM ION, ...
Authors:Silhan, J., Zhao, Q., Boura, E., Thomson, H., Foster, A., Tang, C.M., Freemont, P.S., Baldwin, G.S.
Deposit date:2018-01-23
Release date:2018-10-31
Last modified:2018-12-26
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Structural basis for recognition and repair of the 3'-phosphate by NExo, a base excision DNA repair nuclease from Neisseria meningitidis.
Nucleic Acids Res., 46, 2018
6FKE
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STRUCTURE OF 3' PHOSPHATASE NEXO (D146N) FROM NEISSERIA BOUND TO PRODUCT DNA HAIRPIN
Descriptor:Exodeoxyribonuclease III, DNA (5'-D(*GP*TP*AP*GP*CP*GP*AP*AP*GP*CP*TP*A)-3'), (4S)-2-METHYL-2,4-PENTANEDIOL, ...
Authors:Silhan, J., Zhao, Q., Boura, E., Thomson, H., Foster, A., Tang, C.M., Freemont, P.S., Baldwin, G.S.
Deposit date:2018-01-23
Release date:2018-10-31
Last modified:2018-12-26
Method:X-RAY DIFFRACTION (2.151 Å)
Cite:Structural basis for recognition and repair of the 3'-phosphate by NExo, a base excision DNA repair nuclease from Neisseria meningitidis.
Nucleic Acids Res., 46, 2018
2JC4
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3'-5' EXONUCLEASE (NEXO) FROM NEISSERIA MENINGITIDIS
Descriptor:EXODEOXYRIBONUCLEASE III, MAGNESIUM ION, SODIUM ION, ...
Authors:Carpenter, E.P., Corbett, A., Thomson, H., Adacha, J., Jensen, K., Bergeron, J., Kasampalidis, I., Exley, R., Winterbotham, M., Tang, C., Baldwin, G., Freemont, P.
Deposit date:2006-12-19
Release date:2007-03-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Ap Endonuclease Paralogues with Distinct Activities in DNA Repair and Bacterial Pathogenesis.
Embo J., 26, 2007
1B94
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RESTRICTION ENDONUCLEASE ECORV WITH CALCIUM
Descriptor:DNA (5'-D(*AP*AP*AP*GP*AP*TP*AP*TP*CP*TP*T)-3'), RESTRICTION ENDONUCLEASE ECORV, CALCIUM ION
Authors:Thomas, M.P., Halford, S.E., Brady, R.L.
Deposit date:1999-02-19
Release date:1999-02-26
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural analysis of a mutational hot-spot in the EcoRV restriction endonuclease: a catalytic role for a main chain carbonyl group.
Nucleic Acids Res., 27, 1999
1B95
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ANALYSIS OF A MUTATIONAL HOT-SPOT IN THE ECORV RESTRICTION ENDONUCLEASE: A CATALYTIC ROLE FOR A MAIN CHAIN CARBONYL GROUP
Descriptor:DNA (5'-D(*AP*AP*AP*GP*AP*TP*AP*TP*CP*TP*T)-3'), RESTRICTION ENDONUCLEASE ECORV
Authors:Thomas, M.P., Halford, S.E., Brady, R.L.
Deposit date:1999-02-19
Release date:1999-02-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural analysis of a mutational hot-spot in the EcoRV restriction endonuclease: a catalytic role for a main chain carbonyl group.
Nucleic Acids Res., 27, 1999
1B96
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ANALYSIS OF A MUTATIONAL HOT-SPOT IN THE ECORV RESTRICTION ENDONUCLEASE: A CATALYTIC ROLE FOR A MAIN CHAIN CARBONYL GROUP
Descriptor:DNA (5'-D(*AP*AP*AP*GP*AP*TP*AP*TP*CP*TP*T)-3'), RESTRICTION ENDONUCLEASE ECORV
Authors:Thomas, M.P., Halford, S.E., Brady, R.L.
Deposit date:1999-02-19
Release date:1999-02-26
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural analysis of a mutational hot-spot in the EcoRV restriction endonuclease: a catalytic role for a main chain carbonyl group.
Nucleic Acids Res., 27, 1999
1B97
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ANALYSIS OF A MUTATIONAL HOT-SPOT IN THE ECORV RESTRICTION ENDONUCLEASE: A CATALYTIC ROLE FOR A MAIN CHAIN CARBONYL GROUP
Descriptor:DNA (5'-D(*AP*AP*AP*GP*AP*TP*AP*TP*CP*TP*T)-3'), RESTRICTION ENDONUCLEASE ECORV
Authors:Thomas, M.P., Halford, S.E., Brady, R.L.
Deposit date:1999-02-19
Release date:1999-02-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural analysis of a mutational hot-spot in the EcoRV restriction endonuclease: a catalytic role for a main chain carbonyl group.
Nucleic Acids Res., 27, 1999
2M3K
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GLOBAL FOLD OF THE TYPE IV PILIN COMP FROM NEISSERIA MENINGITIDIS
Descriptor:Minor pilin ComP
Authors:Simpson, P.
Deposit date:2013-01-21
Release date:2013-02-13
Last modified:2013-03-20
Method:SOLUTION NMR
Cite:Specific DNA recognition mediated by a type IV pilin.
Proc.Natl.Acad.Sci.USA, 110, 2013