Author results

1H9G
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FADR, FATTY ACID RESPONSIVE TRANSCRIPTION FACTOR FROM E. COLI, IN COMPLEX WITH MYRISTOYL-COA
Descriptor:FATTY ACID METABOLISM REGULATOR PROTEIN, COENZYME A, MYRISTIC ACID
Authors:Van Aalten, D.M.F., Dirusso, C.C., Knudsen, J.
Deposit date:2001-03-09
Release date:2001-03-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The Structural Basis of Acyl Coenzyme A-Dependent Regulation of the Transcription Factor Fadr
Embo J., 20, 2001
1H9T
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FADR, FATTY ACID RESPONSIVE TRANSCRIPTION FACTOR FROM E. COLI IN COMPLEX WITH FADB OPERATOR
Descriptor:FATTY ACID METABOLISM REGULATOR PROTEIN, 5'-D(*CP*AP*TP*CP*TP*GP*GP*TP*AP*CP*GP*AP* CP*CP*AP*GP*AP*TP*C)-3', 5'-D(*GP*AP*TP*CP*TP*GP*GP*TP*CP*GP*TP*AP* CP*CP*AP*GP*AP*TP*G)-3', ...
Authors:Van Aalten, D.M.F., Dirusso, C.C., Knudsen, J.
Deposit date:2001-03-19
Release date:2001-04-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:The Structural Basis of Acyl Coenzyme A-Dependent Regulation of the Transcription Factor Fadr
Embo J., 20, 2001
1E2X
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FADR, FATTY ACID RESPONSIVE TRANSCRIPTION FACTOR FROM E. COLI
Descriptor:FATTY ACID METABOLISM REGULATOR PROTEIN, SULFATE ION
Authors:Van Aalten, D.M.F., Dirusso, C.C., Knudsen, J., Wierenga, R.K.
Deposit date:2000-05-30
Release date:2000-12-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of Fadr, a Fatty Acid-Responsive Transcription Factor with a Novel Acyl Coenzyme A-Binding Fold
Embo J., 19, 2000
1E15
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CHITINASE B FROM SERRATIA MARCESCENS
Descriptor:CHITINASE B
Authors:Van Aalten, D.M.F., Synstad, B., Brurberg, M.B., Hough, E., Riise, B.W., Eijsink, V.G.H., Wierenga, R.K.
Deposit date:2000-04-18
Release date:2000-08-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of a Two-Domain Chitotriosidase from Serratia Marcescens at 1.9 Angstrom Resoltuion
Proc.Natl.Acad.Sci.USA, 97, 2000
1GSV
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CRYSTAL STRUCTURE OF THE P65 CRYSTAL FORM OF PHOTOACTIVE YELLOW PROTEIN G47S MUTANT
Descriptor:PHOTOACTIVE YELLOW PROTEIN, 4'-HYDROXYCINNAMIC ACID
Authors:Van Aalten, D.M.F., Crielaard, W., Hellingwerf, K.J., Joshua-Tor, L.
Deposit date:2002-01-08
Release date:2002-02-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Engineering Photocycle Dynamics: Crystal Structures and Kinetics of Three Photoactive Yellow Protein Hinge-Bending Mutants
J.Biol.Chem., 227, 2002
1GSW
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CRYSTAL STRUCTURE OF THE P65 CRYSTAL FORM OF PHOTOACTIVE YELLOW PROTEIN G51S MUTANT
Descriptor:PHOTOACTIVE YELLOW PROTEIN, 4'-HYDROXYCINNAMIC ACID
Authors:Van Aalten, D.M.F., Crielaard, W., Hellingwerf, K.J., Joshua-Tor, L.
Deposit date:2002-01-09
Release date:2002-02-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Engineering Photocycle Dynamics: Crystal Structures and Kinetics of Three Photoactive Yellow Protein Hinge-Bending Mutants
J.Biol.Chem., 227, 2002
1GSX
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CRYSTAL STRUCTURE OF THE P65 CRYSTAL FORM OF PHOTOACTIVE YELLOW PROTEIN G47S/G51S MUTANT
Descriptor:PHOTOACTIVE YELLOW PROTEIN, 4'-HYDROXYCINNAMIC ACID
Authors:Van Aalten, D.M.F., Crielaard, W., Hellingwerf, K.J., Joshua-Tor, L.
Deposit date:2002-01-09
Release date:2002-02-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Engineering Photocycle Dynamics: Crystal Structures and Kinetics of Three Photoactive Yellow Protein Hinge-Bending Mutants
J.Biol.Chem., 227, 2002
1E6N
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CHITINASE B FROM SERRATIA MARCESCENS INACTIVE MUTANT E144Q IN COMPLEX WITH N-ACETYLGLUCOSAMINE-PENTAMER
Descriptor:CHITINASE B, N-ACETYL-D-GLUCOSAMINE, SULFATE ION, ...
Authors:Komander, D., Synstad, B., Eijsink, V.G.H., Van Aalten, D.M.F.
Deposit date:2000-08-21
Release date:2001-06-22
Last modified:2011-08-17
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural Insights Into the Catalytic Mechanism of a Family 18 Exo-Chitinase
Proc.Natl.Acad.Sci.USA, 98, 2001
1E6P
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CHITINASE B FROM SERRATIA MARCESCENS INACTIVE MUTANT E144Q
Descriptor:CHITINASE B, GLYCEROL, SULFATE ION
Authors:Komander, D., Synstad, B., Eijsink, V.G.H., Van Aalten, D.M.F.
Deposit date:2000-08-22
Release date:2001-06-22
Last modified:2011-08-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural Insights Into the Catalytic Mechanism of a Family 18 Exo-Chitinase
Proc.Natl.Acad.Sci.USA, 98, 2001
1E6R
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CHITINASE B FROM SERRATIA MARCESCENS WILDTYPE IN COMPLEX WITH INHIBITOR ALLOSAMIDIN
Descriptor:CHITINASE B, N-ACETYL-D-ALLOSAMINE, ALLOSAMIZOLINE, ...
Authors:Komander, D., Synstad, B., Eijsink, V.G.H., Van Aalten, D.M.F.
Deposit date:2000-08-22
Release date:2001-06-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Insights Into the Catalytic Mechanism of a Family 18 Exo-Chitinase
Proc.Natl.Acad.Sci.USA, 98, 2001
1E6Z
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CHITINASE B FROM SERRATIA MARCESCENS WILDTYPE IN COMPLEX WITH CATALYTIC INTERMEDIATE
Descriptor:CHITINASE B, SULFATE ION, 2-METHYL-4,5-DIHYDRO-(1,2-DIDEOXY-ALPHA-D-GLUCOPYRANOSO)[2,1-D]-1,3-OXAZOLE, ...
Authors:Komander, D., Synstad, B., Eijsink, V.G.H., Van Aalten, D.M.F.
Deposit date:2000-08-23
Release date:2001-06-22
Last modified:2017-07-12
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Structural Insights Into the Catalytic Mechanism of a Family 18 Exo-Chitinase
Proc.Natl.Acad.Sci.USA, 98, 2001
4TX6
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AFCHIA1 IN COMPLEX WITH COMPOUND 1
Descriptor:Class III chitinase ChiA1, 3-(2-methoxyphenyl)-6-methyl[1,2]oxazolo[5,4-d]pyrimidin-4(5H)-one, PHOSPHATE ION
Authors:van Aalten, D.M.F.
Deposit date:2014-07-02
Release date:2014-08-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Screening-based discovery of Aspergillus fumigatus plant-type chitinase inhibitors
FEBS Lett, 588, 2014
1GOI
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CRYSTAL STRUCTURE OF THE D140N MUTANT OF CHITINASE B FROM SERRATIA MARCESCENS AT 1.45 A RESOLUTION
Descriptor:CHITINASE B, GLYCEROL, SULFATE ION
Authors:Kolstad, G., Synstad, B., Eijsink, V.G.H., Van Aalten, D.M.F.
Deposit date:2001-10-21
Release date:2001-11-15
Last modified:2011-09-14
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structure of the D140N Mutant of Chitinase B from Serratia Marcescens at 1.45 A Resolution.
Acta Crystallogr.,Sect.D, 58, 2002
1OGB
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CHITINASE B FROM SERRATIA MARCESCENS MUTANT D142N
Descriptor:CHITINASE B, GLYCEROL, SULFATE ION
Authors:Vaaje-Kolstad, G., Houston, D.R., Rao, F.V., Peter, M.G., Synstad, B., van Aalten, D.M.F., Eijsink, V.G.H.
Deposit date:2003-04-29
Release date:2004-04-27
Last modified:2018-02-28
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structure of the D142N Mutant of the Family 18 Chitinase Chib from Serratia Marcescens and its Complex with Allosamidin
Biochim.Biophys.Acta, 1696, 2004
1OGG
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CHITINASE B FROM SERRATIA MARCESCENS MUTANT D142N IN COMPLEX WITH INHIBITOR ALLOSAMIDIN
Descriptor:CHITINASE B, N-ACETYL-D-ALLOSAMINE, ALLOSAMIZOLINE, ...
Authors:Vaaje-Kolstad, G., Houston, D.R., Rao, F.V., Peter, M.G., Synstad, B., van Aalten, D.M.F., Eijsink, V.G.H.
Deposit date:2003-04-30
Release date:2004-04-27
Last modified:2018-02-28
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Structure of the D142N Mutant of the Family 18 Chitinase Chib from Serratia Marcescens and its Complex with Allosamidin
Biochim.Biophys.Acta, 1696, 2004
1UR8
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INTERACTIONS OF A FAMILY 18 CHITINASE WITH THE DESIGNED INHIBITOR HM508, AND ITS DEGRADATION PRODUCT, CHITOBIONO-DELTA-LACTONE
Descriptor:CHITINASE B, GLYCEROL, SULFATE ION, ...
Authors:Vaaje-Kolstad, G., Vasella, A., Peter, M.G., Netter, C., Houston, D.R., Westereng, B., Synstad, B., Eijsink, V.G.H., Van Aalten, D.M.F.
Deposit date:2003-10-27
Release date:2004-04-27
Last modified:2018-05-02
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Interactions of a Family 18 Chitinase with the Designed Inhibitor Hm508 and its Degradation Product, Chitobiono-Delta-Lactone.
J.Biol.Chem., 279, 2004
1UR9
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INTERACTIONS OF A FAMILY 18 CHITINASE WITH THE DESIGNED INHIBITOR HM508, AND ITS DEGRADATION PRODUCT, CHITOBIONO-DELTA-LACTONE
Descriptor:CHITINASE B, GLYCEROL, SULFATE ION, ...
Authors:Vaaje-Kolstad, G., Vasella, A., Peter, M.G., Netter, C., Houston, D.R., Westereng, B., Synstad, B., Eijsink, V.G.H., Van Aalten, D.M.F.
Deposit date:2003-10-27
Release date:2004-04-27
Last modified:2015-04-15
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Interactions of a Family 18 Chitinase with the Designed Inhibitor Hm508 and its Degradation Product, Chitobiono-Delta-Lactone.
J.Biol.Chem., 279, 2004
1W1D
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CRYSTAL STRUCTURE OF THE PDK1 PLECKSTRIN HOMOLOGY (PH) DOMAIN BOUND TO INOSITOL (1,3,4,5)-TETRAKISPHOSPHATE
Descriptor:3-PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE-1, GLYCEROL, GOLD ION, ...
Authors:Komander, D., Deak, M., Alessi, D.R., Van Aalten, D.M.F.
Deposit date:2004-06-21
Release date:2004-11-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural Insights Into the Regulation of Pdk1 by Phosphoinositides and Inositol Phosphates
Embo J., 23, 2004
1ODV
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PHOTOACTIVE YELLOW PROTEIN 1-25 DELETION MUTANT
Descriptor:PHOTOACTIVE YELLOW PROTEIN, 4'-HYDROXYCINNAMIC ACID
Authors:Vreede, J., Van Der horst, M.A., Hellingwerf, K.J., Crielaard, W., Van Aalten, D.M.F.
Deposit date:2003-03-14
Release date:2003-03-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.14 Å)
Cite:Pas Domains.Common Structure and Common Flexibility
J.Biol.Chem., 278, 2003
2VKI
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STRUCTURE OF THE PDK1 PH DOMAIN K465E MUTANT
Descriptor:3-PHOPSHOINOSITIDE DEPENDENT PROTEIN KINASE 1, GLYCEROL, SULFATE ION
Authors:Komander, D., Bayascas, J.R., Deak, M., Alessi, D.R., van Aalten, D.M.F.
Deposit date:2007-12-19
Release date:2008-05-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Mutation of the Pdk1 Ph Domain Inhibits Protein Kinase B/Akt, Leading to Small Size and Insulin Resistance.
Mol.Cell.Biol., 28, 2008
1EAZ
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CRYSTAL STRUCTURE OF THE PHOSPHOINOSITOL (3,4)-BISPHOSPHATE BINDING PH DOMAIN OF TAPP1 FROM HUMAN.
Descriptor:TANDEM PH DOMAIN CONTAINING PROTEIN-1, CITRIC ACID
Authors:Thomas, C.C., Dowler, S., Deak, M., Alessi, D.R., Van Aalten, D.M.F.
Deposit date:2001-07-17
Release date:2002-07-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal Structure of the Phosphatidylinositol 3,4-Bisphosphate-Binding Pleckstrin Homology (Ph) Domain of Tandem Ph-Domain-Containing Protein 1 (Tapp1): Molecular Basis of Lipid Specificity
Biochem.J., 358, 2001
1GUV
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STRUCTURE OF HUMAN CHITOTRIOSIDASE
Descriptor:CHITOTRIOSIDASE, 1,2-ETHANEDIOL
Authors:Von Moeller, H., Houston, D., Boot, R.G., Aerts, J.M.F.G., Van Aalten, D.M.F.
Deposit date:2002-01-31
Release date:2003-03-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structure of Human Chitotriosidase - Implications for Specific Inhibitor Design and Function of Mammalian Chitinase-Like Lectins
J.Biol.Chem., 277, 2002
1H10
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HIGH RESOLUTION STRUCTURE OF THE PLECKSTRIN HOMOLOGY DOMAIN OF PROTEIN KINASE B/AKT BOUND TO INS(1,3,4,5)-TETRAKISPHOPHATE
Descriptor:RAC-ALPHA SERINE/THREONINE KINASE, INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE
Authors:Thomas, C.C., Deak, M., Alessi, D.R., Van Aalten, D.M.F.
Deposit date:2002-07-01
Release date:2003-06-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:High Resolution Structure of the Pleckstrin Homology Domain of Protein Kinase B/Akt Bound to Phosphatidylinositol (3,4,5)-Trisphosphate
Curr.Biol., 12, 2002
1H1W
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HIGH RESOLUTION CRYSTAL STRUCTURE OF THE HUMAN PDK1 CATALYTIC DOMAIN
Descriptor:3-PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE-1, GLYCEROL, SULFATE ION, ...
Authors:Biondi, R.M., Komander, D., Thomas, C.C., Lizcano, J.M., Deak, M., Alessi, D.R., Van Aalten, D.M.F.
Deposit date:2002-07-23
Release date:2003-07-17
Last modified:2011-09-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:High Resolution Crystal Structure of the Human Pdk1 Catalytic Domain Defines the Regulatory Phosphopeptide Docking Site
Embo J., 21, 2003
1HJV
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CRYSTAL STRUCTURE OF HCGP-39 IN COMPLEX WITH CHITIN TETRAMER
Descriptor:CHITINASE-3 LIKE PROTEIN 1, N-ACETYL-D-GLUCOSAMINE, SULFATE ION
Authors:Houston, D.R., Recklies, A.D., Krupa, J.C., Van Aalten, D.M.F.
Deposit date:2003-02-28
Release date:2003-03-11
Last modified:2012-08-22
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structure and Ligand-Induced Conformational Change of the 39-kDa Glycoprotein from Human Articular Chondrocytes.
J.Biol.Chem., 278, 2003