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1H6I
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A REFINED STRUCTURE OF HUMAN AQUAPORIN 1
Descriptor:AQUAPORIN-1
Authors:De Groot, B.L., Engel, A., Grubmuller, H.
Deposit date:2001-06-15
Release date:2001-12-13
Last modified:2011-07-13
Method:ELECTRON CRYSTALLOGRAPHY (3.54 Å)
Cite:A Refined Structure of Human Aquaporin 1
FEBS Lett., 504, 2001
1LOH
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STREPTOCOCCUS PNEUMONIAE HYALURONATE LYASE IN COMPLEX WITH HEXASACCHARIDE HYALURONAN SUBSTRATE
Descriptor:Hyaluronate Lyase, N-ACETYL-D-GLUCOSAMINE, BETA-D-GLUCOPYRANURONIC ACID
Authors:Jedrzejas, M.J., Mello, L.V., De Groot, B.L., Li, S.
Deposit date:2002-05-06
Release date:2002-08-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Mechanism of hyaluronan degradation by Streptococcus pneumoniae hyaluronate lyase. Structures of complexes with the substrate.
J.Biol.Chem., 277, 2002
1LXK
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STREPTOCOCCUS PNEUMONIAE HYALURONATE LYASE IN COMPLEX WITH TETRASACCHARIDE HYALURONAN SUBSTRATE
Descriptor:Hyaluronate Lyase, N-ACETYL-D-GLUCOSAMINE, BETA-D-GLUCOPYRANURONIC ACID
Authors:Jedrzejas, M.J., Mello, L.V., De Groot, B.L., Li, S.
Deposit date:2002-06-05
Release date:2002-08-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:Mechanism of hyaluronan degradation by Streptococcus pneumoniae hyaluronate lyase. Structures of complexes with the substrate.
J.Biol.Chem., 277, 2002
1LXM
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CRYSTAL STRUCTURE OF STREPTOCOCCUS AGALACTIAE HYALURONATE LYASE COMPLEXED WITH HEXASACCHARIDE UNIT OF HYALURONAN
Descriptor:HYALURONATE Lyase, N-ACETYL-D-GLUCOSAMINE, BETA-D-GLUCOPYRANURONIC ACID
Authors:Mello, L.V., de Groot, B.L., Li, S., Jedrzejas, M.J.
Deposit date:2002-06-05
Release date:2002-10-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure and flexibility of Streptococcus agalactiae hyaluronate lyase complex with its substrate. Insights into the mechanism of processive degradation of hyaluronan.
J.Biol.Chem., 277, 2002
2K39
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RECOGNITION DYNAMICS UP TO MICROSECONDS REVEALED FROM RDC DERIVED UBIQUITIN ENSEMBLE IN SOLUTION
Descriptor:Ubiquitin
Authors:Lange, O.F., Lakomek, N.A., Fares, C., Schroder, G., Walter, K., Becker, S., Meiler, J., Grubmuller, H., Griesinger, C., de Groot, B.L.
Deposit date:2008-04-25
Release date:2008-06-24
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Recognition dynamics up to microseconds revealed from an RDC-derived ubiquitin ensemble in solution.
Science, 320, 2008
2W1P
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1.4 ANGSTROM CRYSTAL STRUCTURE OF P.PASTORIS AQUAPORIN, AQY1, IN A CLOSED CONFORMATION AT PH 8.0
Descriptor:AQUAPORIN PIP2-7 7;, B-OCTYLGLUCOSIDE, CHLORIDE ION
Authors:Fischer, G., Kosinska-Eriksson, U., Aponte-Santamaria, C., Palmgren, M., Geijer, C., Hedfalk, K., Hohmann, S., de Groot, B.L., Neutze, R., Lindkvist-Petersson, K.
Deposit date:2008-10-20
Release date:2009-06-16
Last modified:2012-04-11
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal Structure of a Yeast Aquaporin at 1.15 A Reveals a Novel Gating Mechanism
Plos Biol., 7, 2009
2W2E
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1.15 ANGSTROM CRYSTAL STRUCTURE OF P.PASTORIS AQUAPORIN, AQY1, IN A CLOSED CONFORMATION AT PH 3.5
Descriptor:AQUAPORIN PIP2-7 7, B-OCTYLGLUCOSIDE, CHLORIDE ION
Authors:Fischer, G., Kosinska-Eriksson, U., Aponte-Santamaria, C., Palmgren, M., Geijer, C., Hedfalk, K., Hohmann, S., de Groot, B.L., Neutze, R., Lindkvist-Petersson, K.
Deposit date:2008-10-29
Release date:2009-06-16
Last modified:2012-04-11
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Crystal Structure of a Yeast Aquaporin at 1.15 A Reveals a Novel Gating Mechanism.1.15 A
Plos Biol., 7, 2009
4UN2
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CRYSTAL STRUCTURE OF THE UBA DOMAIN OF DSK2 IN COMPLEX WITH UBIQUITIN
Descriptor:UBIQUITIN, UBIQUITIN DOMAIN-CONTAINING PROTEIN DSK2
Authors:Michielssens, S., Peters, J.H., Ban, D., Pratihar, S., Seeliger, D., Sharma, M., Giller, K., Sabo, T.M., Becker, S., Lee, D., Griesinger, C., de Groot, B.L.
Deposit date:2014-05-23
Release date:2014-08-27
Last modified:2014-09-24
Method:X-RAY DIFFRACTION (1.51 Å)
Cite:A Designed Conformational Shift to Control Protein Binding Specificity.
Angew.Chem.Int.Ed.Engl., 53, 2014
5NFE
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NEUTRON STRUCTURE OF HUMAN TRANSTHYRETIN (TTR) T119M MUTANT AT ROOM TEMPERATURE TO 1.85A RESOLUTION
Descriptor:Transthyretin
Authors:Yee, A.W., Moulin, M., Blakeley, M.P., Ostermann, A., Cooper, J.B., Haertlein, M., Mitchell, E.P., Forsyth, V.T.
Deposit date:2017-03-14
Release date:2019-01-02
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (1.853 Å), NEUTRON DIFFRACTION
Cite:A molecular mechanism for transthyretin amyloidogenesis.
Nat Commun, 10, 2019
5NFW
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NEUTRON STRUCTURE OF HUMAN TRANSTHYRETIN (TTR) S52P MUTANT AT ROOM TEMPERATURE TO 1.8A RESOLUTION (QUASI-LAUE)
Descriptor:Transthyretin
Authors:Yee, A.W., Moulin, M., Blakeley, M.P., Cooper, J.B., Haertlein, M., Mitchell, E.P., Forsyth, V.T.
Deposit date:2017-03-16
Release date:2019-01-02
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (1.8 Å), NEUTRON DIFFRACTION
Cite:A molecular mechanism for transthyretin amyloidogenesis.
Nat Commun, 10, 2019
6FFT
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NEUTRON STRUCTURE OF HUMAN TRANSTHYRETIN (TTR) S52P MUTANT IN COMPLEX WITH TAFAMIDIS AT ROOM TEMPERATURE TO 2A RESOLUTION (QUASI-LAUE)
Descriptor:Transthyretin, 2-(3,5-dichlorophenyl)-1,3-benzoxazole-6-carboxylic acid
Authors:Yee, A.W., Moulin, M., Blakeley, M.P., Haertlein, M., Mitchell, E.P., Forsyth, V.T.
Deposit date:2018-01-09
Release date:2019-01-02
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (2 Å), NEUTRON DIFFRACTION
Cite:A molecular mechanism for transthyretin amyloidogenesis.
Nat Commun, 10, 2019
2BRV
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CRYSTAL STRUCTURE OF STREPTOCOCCUS PNEUMONIAE HYALURONATE LYASE FROM 70PERCENT SATURATED MALONATE.
Descriptor:HYALURONATE LYASE, MALONIC ACID
Authors:Rigden, D.J., Jedrzejas, M.J.
Deposit date:2005-05-11
Release date:2006-04-05
Last modified:2015-04-22
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Alternate Structural Conformations of Streptococcus Pneumoniae Hyaluronan Lyase: Insights Into Enzyme Flexibility and Underlying Molecular Mechanism of Action.
J.Mol.Biol., 358, 2006
2BRW
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CRYSTAL STRUCTURE OF STREPTOCOCCUS PNEUMONIAE HYALURONATE LYASE FROM 30PERCENT PEGMME.
Descriptor:HYALURONATE LYASE, SULFATE ION
Authors:Rigden, D.J., Littlejohn, J.E., Jedrzejas, M.J.
Deposit date:2005-05-11
Release date:2006-04-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Alternate Structural Conformations of Streptococcus Pneumoniae Hyaluronan Lyase: Insights Into Enzyme Flexibility and Underlying Molecular Mechanism of Action.
J.Mol.Biol., 358, 2006
2RKO
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CRYSTAL STRUCTURE OF THE VPS4P-DIMER
Descriptor:Vacuolar protein sorting-associated protein 4
Authors:Hartmann, C., Gruetter, M.G.
Deposit date:2007-10-17
Release date:2008-02-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:Vacuolar protein sorting: two different functional states of the AAA-ATPase Vps4p
J.Mol.Biol., 377, 2008
2WFI
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ATOMIC RESOLUTION CRYSTAL STRUCTURE OF THE PPIASE DOMAIN OF HUMAN CYCLOPHILIN G
Descriptor:PEPTIDYL-PROLYL CIS-TRANS ISOMERASE G, MAGNESIUM ION
Authors:Stegmann, C.M., Sheldrick, G.M., Wahl, M.C.
Deposit date:2009-04-06
Release date:2009-06-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (0.75 Å)
Cite:The Thermodynamic Influence of Trapped Water Molecules on a Protein-Ligand Interaction
Angew.Chem.Int.Ed.Engl., 48, 2009
2WFJ
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ATOMIC RESOLUTION CRYSTAL STRUCTURE OF THE PPIASE DOMAIN OF HUMAN CYCLOPHILIN G IN COMPLEX WITH CYCLOSPORIN A.
Descriptor:PEPTIDYL-PROLYL CIS-TRANS ISOMERASE G, CYCLOSPORIN A, 1,2-ETHANEDIOL, ...
Authors:Stegmann, C.M., Sheldrick, G.M., Wahl, M.C.
Deposit date:2009-04-06
Release date:2009-06-16
Last modified:2012-11-30
Method:X-RAY DIFFRACTION (0.75 Å)
Cite:The Thermodynamic Influence of Trapped Water Molecules on a Protein-Ligand Interaction.
Angew.Chem.Int.Ed.Engl., 48, 2009
2YMK
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CRYSTAL STRUCTURE OF THE HEXAMERIC ANTI-MICROBIAL PEPTIDE CHANNEL DERMCIDIN
Descriptor:DCD-1, ZINC ION
Authors:Zeth, K.
Deposit date:2012-10-09
Release date:2012-10-17
Last modified:2013-12-25
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Crystal Structure and Functional Mechanism of a Human Antimicrobial Membrane Channel.
Proc.Natl.Acad.Sci.USA, 110, 2013
5I32
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AMMONIA PERMEABLE AQUAPORIN ATTIP2;1
Descriptor:Aquaporin TIP2-1
Authors:Kirscht, A., Nissen, P., Kjellbom, P., Gourdon, P., Johanson, U.
Deposit date:2016-02-09
Release date:2016-04-06
Method:X-RAY DIFFRACTION (1.18 Å)
Cite:Crystal Structure of an Ammonia-Permeable Aquaporin.
Plos Biol., 14, 2016
5J4I
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CRYSTAL STRUCTURE OF THE L-ARGININE/AGMATINE ANTIPORTER FROM E. COLI AT 2.2 ANGSTROEM RESOLUTION
Descriptor:Arginine/agmatine antiporter
Authors:Jeckelmann, J.M., Ilgue, H., Fotiadis, D.
Deposit date:2016-04-01
Release date:2016-08-31
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (2.207 Å)
Cite:Insights into the molecular basis for substrate binding and specificity of the wild-type L-arginine/agmatine antiporter AdiC.
Proc.Natl.Acad.Sci.USA, 113, 2016
5J4N
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CRYSTAL STRUCTURE OF THE L-ARGININE/AGMATINE ANTIPORTER ADIC IN COMPLEX WITH AGMATINE AT 2.6 ANGSTROEM RESOLUTION
Descriptor:Arginine/agmatine antiporter, AGMATINE
Authors:Jeckelmann, J.M., Ilgue, H., Fotiadis, D.
Deposit date:2016-04-01
Release date:2016-08-31
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (2.594 Å)
Cite:Insights into the molecular basis for substrate binding and specificity of the wild-type L-arginine/agmatine antiporter AdiC.
Proc.Natl.Acad.Sci.USA, 113, 2016
3ZOJ
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HIGH-RESOLUTION STRUCTURE OF PICHIA PASTORIS AQUAPORIN AQY1 AT 0.88 A
Descriptor:AQUAPORIN, B-OCTYLGLUCOSIDE, CHLORIDE ION
Authors:Kosinska-Eriksson, U., Fischer, G., Friemann, R., Enkavi, G., Tajkhorshid, E., Neutze, R.
Deposit date:2013-02-21
Release date:2013-06-26
Last modified:2013-07-03
Method:X-RAY DIFFRACTION (0.88 Å)
Cite:Subangstrom Resolution X-Ray Structure Details Aquaporin-Water Interactions
Science, 340, 2013