1H9G | | FADR, FATTY ACID RESPONSIVE TRANSCRIPTION FACTOR FROM E. COLI, IN COMPLEX WITH MYRISTOYL-COA | | Descriptor: | FATTY ACID METABOLISM REGULATOR PROTEIN, COENZYME A, MYRISTIC ACID | | Authors: | Van Aalten, D.M.F., Dirusso, C.C., Knudsen, J. | | Deposit date: | 2001-03-09 | | Release date: | 2001-03-09 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | The Structural Basis of Acyl Coenzyme A-Dependent Regulation of the Transcription Factor Fadr
Embo J., 20, 2001
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1H9T | | FADR, FATTY ACID RESPONSIVE TRANSCRIPTION FACTOR FROM E. COLI IN COMPLEX WITH FADB OPERATOR | | Descriptor: | FATTY ACID METABOLISM REGULATOR PROTEIN, 5'-D(*CP*AP*TP*CP*TP*GP*GP*TP*AP*CP*GP*AP* CP*CP*AP*GP*AP*TP*C)-3', 5'-D(*GP*AP*TP*CP*TP*GP*GP*TP*CP*GP*TP*AP* CP*CP*AP*GP*AP*TP*G)-3', ... | | Authors: | Van Aalten, D.M.F., Dirusso, C.C., Knudsen, J. | | Deposit date: | 2001-03-19 | | Release date: | 2001-04-04 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (3.25 Å) | | Cite: | The Structural Basis of Acyl Coenzyme A-Dependent Regulation of the Transcription Factor Fadr
Embo J., 20, 2001
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1E2X | | FADR, FATTY ACID RESPONSIVE TRANSCRIPTION FACTOR FROM E. COLI | | Descriptor: | FATTY ACID METABOLISM REGULATOR PROTEIN, SULFATE ION | | Authors: | Van Aalten, D.M.F., Dirusso, C.C., Knudsen, J., Wierenga, R.K. | | Deposit date: | 2000-05-30 | | Release date: | 2000-12-03 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal Structure of Fadr, a Fatty Acid-Responsive Transcription Factor with a Novel Acyl Coenzyme A-Binding Fold
Embo J., 19, 2000
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1E15 | | CHITINASE B FROM SERRATIA MARCESCENS | | Descriptor: | CHITINASE B | | Authors: | Van Aalten, D.M.F., Synstad, B., Brurberg, M.B., Hough, E., Riise, B.W., Eijsink, V.G.H., Wierenga, R.K. | | Deposit date: | 2000-04-18 | | Release date: | 2000-08-18 | | Last modified: | 2019-07-24 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structure of a Two-Domain Chitotriosidase from Serratia Marcescens at 1.9 Angstrom Resoltuion
Proc.Natl.Acad.Sci.USA, 97, 2000
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1GSV | | CRYSTAL STRUCTURE OF THE P65 CRYSTAL FORM OF PHOTOACTIVE YELLOW PROTEIN G47S MUTANT | | Descriptor: | PHOTOACTIVE YELLOW PROTEIN, 4'-HYDROXYCINNAMIC ACID | | Authors: | Van Aalten, D.M.F., Crielaard, W., Hellingwerf, K.J., Joshua-Tor, L. | | Deposit date: | 2002-01-08 | | Release date: | 2002-02-14 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Engineering Photocycle Dynamics: Crystal Structures and Kinetics of Three Photoactive Yellow Protein Hinge-Bending Mutants
J.Biol.Chem., 227, 2002
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1GSW | | CRYSTAL STRUCTURE OF THE P65 CRYSTAL FORM OF PHOTOACTIVE YELLOW PROTEIN G51S MUTANT | | Descriptor: | PHOTOACTIVE YELLOW PROTEIN, 4'-HYDROXYCINNAMIC ACID | | Authors: | Van Aalten, D.M.F., Crielaard, W., Hellingwerf, K.J., Joshua-Tor, L. | | Deposit date: | 2002-01-09 | | Release date: | 2002-02-14 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Engineering Photocycle Dynamics: Crystal Structures and Kinetics of Three Photoactive Yellow Protein Hinge-Bending Mutants
J.Biol.Chem., 227, 2002
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1GSX | | CRYSTAL STRUCTURE OF THE P65 CRYSTAL FORM OF PHOTOACTIVE YELLOW PROTEIN G47S/G51S MUTANT | | Descriptor: | PHOTOACTIVE YELLOW PROTEIN, 4'-HYDROXYCINNAMIC ACID | | Authors: | Van Aalten, D.M.F., Crielaard, W., Hellingwerf, K.J., Joshua-Tor, L. | | Deposit date: | 2002-01-09 | | Release date: | 2002-02-14 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.79 Å) | | Cite: | Engineering Photocycle Dynamics: Crystal Structures and Kinetics of Three Photoactive Yellow Protein Hinge-Bending Mutants
J.Biol.Chem., 227, 2002
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1E6N | | CHITINASE B FROM SERRATIA MARCESCENS INACTIVE MUTANT E144Q IN COMPLEX WITH N-ACETYLGLUCOSAMINE-PENTAMER | | Descriptor: | CHITINASE B, N-ACETYL-D-GLUCOSAMINE, SULFATE ION, ... | | Authors: | Komander, D., Synstad, B., Eijsink, V.G.H., Van Aalten, D.M.F. | | Deposit date: | 2000-08-21 | | Release date: | 2001-06-22 | | Last modified: | 2011-08-17 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Structural Insights Into the Catalytic Mechanism of a Family 18 Exo-Chitinase
Proc.Natl.Acad.Sci.USA, 98, 2001
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1E6P | | CHITINASE B FROM SERRATIA MARCESCENS INACTIVE MUTANT E144Q | | Descriptor: | CHITINASE B, GLYCEROL, SULFATE ION | | Authors: | Komander, D., Synstad, B., Eijsink, V.G.H., Van Aalten, D.M.F. | | Deposit date: | 2000-08-22 | | Release date: | 2001-06-22 | | Last modified: | 2011-08-24 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structural Insights Into the Catalytic Mechanism of a Family 18 Exo-Chitinase
Proc.Natl.Acad.Sci.USA, 98, 2001
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1E6R | | CHITINASE B FROM SERRATIA MARCESCENS WILDTYPE IN COMPLEX WITH INHIBITOR ALLOSAMIDIN | | Descriptor: | CHITINASE B, N-ACETYL-D-ALLOSAMINE, ALLOSAMIZOLINE, ... | | Authors: | Komander, D., Synstad, B., Eijsink, V.G.H., Van Aalten, D.M.F. | | Deposit date: | 2000-08-22 | | Release date: | 2001-06-22 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural Insights Into the Catalytic Mechanism of a Family 18 Exo-Chitinase
Proc.Natl.Acad.Sci.USA, 98, 2001
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1E6Z | | CHITINASE B FROM SERRATIA MARCESCENS WILDTYPE IN COMPLEX WITH CATALYTIC INTERMEDIATE | | Descriptor: | CHITINASE B, SULFATE ION, 2-METHYL-4,5-DIHYDRO-(1,2-DIDEOXY-ALPHA-D-GLUCOPYRANOSO)[2,1-D]-1,3-OXAZOLE, ... | | Authors: | Komander, D., Synstad, B., Eijsink, V.G.H., Van Aalten, D.M.F. | | Deposit date: | 2000-08-23 | | Release date: | 2001-06-22 | | Last modified: | 2019-07-24 | | Method: | X-RAY DIFFRACTION (1.99 Å) | | Cite: | Structural Insights Into the Catalytic Mechanism of a Family 18 Exo-Chitinase
Proc.Natl.Acad.Sci.USA, 98, 2001
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4TX6 | | AFCHIA1 IN COMPLEX WITH COMPOUND 1 | | Descriptor: | Class III chitinase ChiA1, 3-(2-methoxyphenyl)-6-methyl[1,2]oxazolo[5,4-d]pyrimidin-4(5H)-one, PHOSPHATE ION | | Authors: | van Aalten, D.M.F. | | Deposit date: | 2014-07-02 | | Release date: | 2014-08-06 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Screening-based discovery of Aspergillus fumigatus plant-type chitinase inhibitors
FEBS Lett, 588, 2014
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1GOI | | CRYSTAL STRUCTURE OF THE D140N MUTANT OF CHITINASE B FROM SERRATIA MARCESCENS AT 1.45 A RESOLUTION | | Descriptor: | CHITINASE B, GLYCEROL, SULFATE ION | | Authors: | Kolstad, G., Synstad, B., Eijsink, V.G.H., Van Aalten, D.M.F. | | Deposit date: | 2001-10-21 | | Release date: | 2001-11-15 | | Last modified: | 2011-09-14 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | Structure of the D140N Mutant of Chitinase B from Serratia Marcescens at 1.45 A Resolution.
Acta Crystallogr.,Sect.D, 58, 2002
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1OGB | | CHITINASE B FROM SERRATIA MARCESCENS MUTANT D142N | | Descriptor: | CHITINASE B, GLYCEROL, SULFATE ION | | Authors: | Vaaje-Kolstad, G., Houston, D.R., Rao, F.V., Peter, M.G., Synstad, B., van Aalten, D.M.F., Eijsink, V.G.H. | | Deposit date: | 2003-04-29 | | Release date: | 2004-04-27 | | Last modified: | 2018-02-28 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Structure of the D142N Mutant of the Family 18 Chitinase Chib from Serratia Marcescens and its Complex with Allosamidin
Biochim.Biophys.Acta, 1696, 2004
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1OGG | | CHITINASE B FROM SERRATIA MARCESCENS MUTANT D142N IN COMPLEX WITH INHIBITOR ALLOSAMIDIN | | Descriptor: | CHITINASE B, N-ACETYL-D-ALLOSAMINE, ALLOSAMIZOLINE, ... | | Authors: | Vaaje-Kolstad, G., Houston, D.R., Rao, F.V., Peter, M.G., Synstad, B., van Aalten, D.M.F., Eijsink, V.G.H. | | Deposit date: | 2003-04-30 | | Release date: | 2004-04-27 | | Last modified: | 2018-02-28 | | Method: | X-RAY DIFFRACTION (1.97 Å) | | Cite: | Structure of the D142N Mutant of the Family 18 Chitinase Chib from Serratia Marcescens and its Complex with Allosamidin
Biochim.Biophys.Acta, 1696, 2004
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1UR8 | | INTERACTIONS OF A FAMILY 18 CHITINASE WITH THE DESIGNED INHIBITOR HM508, AND ITS DEGRADATION PRODUCT, CHITOBIONO-DELTA-LACTONE | | Descriptor: | CHITINASE B, GLYCEROL, SULFATE ION, ... | | Authors: | Vaaje-Kolstad, G., Vasella, A., Peter, M.G., Netter, C., Houston, D.R., Westereng, B., Synstad, B., Eijsink, V.G.H., Van Aalten, D.M.F. | | Deposit date: | 2003-10-27 | | Release date: | 2004-04-27 | | Last modified: | 2018-05-02 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Interactions of a Family 18 Chitinase with the Designed Inhibitor Hm508 and its Degradation Product, Chitobiono-Delta-Lactone.
J.Biol.Chem., 279, 2004
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1UR9 | | INTERACTIONS OF A FAMILY 18 CHITINASE WITH THE DESIGNED INHIBITOR HM508, AND ITS DEGRADATION PRODUCT, CHITOBIONO-DELTA-LACTONE | | Descriptor: | CHITINASE B, GLYCEROL, SULFATE ION, ... | | Authors: | Vaaje-Kolstad, G., Vasella, A., Peter, M.G., Netter, C., Houston, D.R., Westereng, B., Synstad, B., Eijsink, V.G.H., Van Aalten, D.M.F. | | Deposit date: | 2003-10-27 | | Release date: | 2004-04-27 | | Last modified: | 2015-04-15 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Interactions of a Family 18 Chitinase with the Designed Inhibitor Hm508 and its Degradation Product, Chitobiono-Delta-Lactone.
J.Biol.Chem., 279, 2004
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1W1D | | CRYSTAL STRUCTURE OF THE PDK1 PLECKSTRIN HOMOLOGY (PH) DOMAIN BOUND TO INOSITOL (1,3,4,5)-TETRAKISPHOSPHATE | | Descriptor: | 3-PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE-1, GLYCEROL, GOLD ION, ... | | Authors: | Komander, D., Deak, M., Alessi, D.R., Van Aalten, D.M.F. | | Deposit date: | 2004-06-21 | | Release date: | 2004-11-19 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Structural Insights Into the Regulation of Pdk1 by Phosphoinositides and Inositol Phosphates
Embo J., 23, 2004
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1ODV | | PHOTOACTIVE YELLOW PROTEIN 1-25 DELETION MUTANT | | Descriptor: | PHOTOACTIVE YELLOW PROTEIN, 4'-HYDROXYCINNAMIC ACID | | Authors: | Vreede, J., Van Der horst, M.A., Hellingwerf, K.J., Crielaard, W., Van Aalten, D.M.F. | | Deposit date: | 2003-03-14 | | Release date: | 2003-03-18 | | Last modified: | 2019-05-22 | | Method: | X-RAY DIFFRACTION (1.14 Å) | | Cite: | Pas Domains.Common Structure and Common Flexibility
J.Biol.Chem., 278, 2003
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2VKI | | STRUCTURE OF THE PDK1 PH DOMAIN K465E MUTANT | | Descriptor: | 3-PHOPSHOINOSITIDE DEPENDENT PROTEIN KINASE 1, GLYCEROL, SULFATE ION | | Authors: | Komander, D., Bayascas, J.R., Deak, M., Alessi, D.R., van Aalten, D.M.F. | | Deposit date: | 2007-12-19 | | Release date: | 2008-05-13 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Mutation of the Pdk1 Ph Domain Inhibits Protein Kinase B/Akt, Leading to Small Size and Insulin Resistance.
Mol.Cell.Biol., 28, 2008
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1EAZ | | CRYSTAL STRUCTURE OF THE PHOSPHOINOSITOL (3,4)-BISPHOSPHATE BINDING PH DOMAIN OF TAPP1 FROM HUMAN. | | Descriptor: | TANDEM PH DOMAIN CONTAINING PROTEIN-1, CITRIC ACID | | Authors: | Thomas, C.C., Dowler, S., Deak, M., Alessi, D.R., Van Aalten, D.M.F. | | Deposit date: | 2001-07-17 | | Release date: | 2002-07-11 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Crystal Structure of the Phosphatidylinositol 3,4-Bisphosphate-Binding Pleckstrin Homology (Ph) Domain of Tandem Ph-Domain-Containing Protein 1 (Tapp1): Molecular Basis of Lipid Specificity
Biochem.J., 358, 2001
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1GUV | | STRUCTURE OF HUMAN CHITOTRIOSIDASE | | Descriptor: | CHITOTRIOSIDASE, 1,2-ETHANEDIOL | | Authors: | Von Moeller, H., Houston, D., Boot, R.G., Aerts, J.M.F.G., Van Aalten, D.M.F. | | Deposit date: | 2002-01-31 | | Release date: | 2003-03-30 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Structure of Human Chitotriosidase - Implications for Specific Inhibitor Design and Function of Mammalian Chitinase-Like Lectins
J.Biol.Chem., 277, 2002
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1H10 | | HIGH RESOLUTION STRUCTURE OF THE PLECKSTRIN HOMOLOGY DOMAIN OF PROTEIN KINASE B/AKT BOUND TO INS(1,3,4,5)-TETRAKISPHOPHATE | | Descriptor: | RAC-ALPHA SERINE/THREONINE KINASE, INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE | | Authors: | Thomas, C.C., Deak, M., Alessi, D.R., Van Aalten, D.M.F. | | Deposit date: | 2002-07-01 | | Release date: | 2003-06-27 | | Last modified: | 2019-05-22 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | High Resolution Structure of the Pleckstrin Homology Domain of Protein Kinase B/Akt Bound to Phosphatidylinositol (3,4,5)-Trisphosphate
Curr.Biol., 12, 2002
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1H1W | | HIGH RESOLUTION CRYSTAL STRUCTURE OF THE HUMAN PDK1 CATALYTIC DOMAIN | | Descriptor: | 3-PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE-1, GLYCEROL, SULFATE ION, ... | | Authors: | Biondi, R.M., Komander, D., Thomas, C.C., Lizcano, J.M., Deak, M., Alessi, D.R., Van Aalten, D.M.F. | | Deposit date: | 2002-07-23 | | Release date: | 2003-07-17 | | Last modified: | 2011-09-14 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | High Resolution Crystal Structure of the Human Pdk1 Catalytic Domain Defines the Regulatory Phosphopeptide Docking Site
Embo J., 21, 2003
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1HJV | | CRYSTAL STRUCTURE OF HCGP-39 IN COMPLEX WITH CHITIN TETRAMER | | Descriptor: | CHITINASE-3 LIKE PROTEIN 1, N-ACETYL-D-GLUCOSAMINE, SULFATE ION | | Authors: | Houston, D.R., Recklies, A.D., Krupa, J.C., Van Aalten, D.M.F. | | Deposit date: | 2003-02-28 | | Release date: | 2003-03-11 | | Last modified: | 2019-07-24 | | Method: | X-RAY DIFFRACTION (2.75 Å) | | Cite: | Structure and Ligand-Induced Conformational Change of the 39-kDa Glycoprotein from Human Articular Chondrocytes.
J.Biol.Chem., 278, 2003
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