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The crystal structure of Corynebacterium glutamicum dihydrodipicolinate synthase to 2.2 A resolution
Descriptor:	Dihydrodipicolinate synthetase
Authors:	Rydel, T.J, Sturman, E.J, Rice, E.A.
Deposit date:	2008-04-01
Release date:	2008-11-18
Last modified:	2023-11-29
Method:	X-RAY DIFFRACTION (2.2 Å)
Cite:	Characterization and crystal structure of lysine insensitive Corynebacterium glutamicum dihydrodipicolinate synthase (cDHDPS) protein. Arch.Biochem.Biophys., 480, 2008

Crystal Structure of Human Beta Secretase Complexed with inhibitor
Descriptor:	3-({[(1R)-1-(4-FLUOROPHENYL)ETHYL]AMINO}CARBONYL)-5-[METHYL(METHYLSULFONYL)AMINO]BENZYL ALPHA-METHYL-D-PHENYLALANINATE, Beta-secretase 1, SULFATE ION
Authors:	Munshi, S.
Deposit date:	2007-04-10
Release date:	2007-06-05
Last modified:	2023-08-30
Method:	X-RAY DIFFRACTION (2 Å)
Cite:	Design, synthesis, and SAR of macrocyclic tertiary carbinamine BACE-1 inhibitors. Bioorg.Med.Chem.Lett., 17, 2007

Crystal Structure of Human Beta Secretase Complexed with inhibitor
Descriptor:	Beta-secretase 1, N-[(5R,14R)-5-AMINO-5,14-DIMETHYL-4-OXO-3-OXA-18-AZATRICYCLO[15.3.1.1~7,11~]DOCOSA-1(21),7(22),8,10,17,19-HEXAEN-19-YL]-N-METHYLMETHANESULFONAMIDE, SULFATE ION
Authors:	Munshi, S.
Deposit date:	2007-04-10
Release date:	2008-04-22
Last modified:	2023-08-30
Method:	X-RAY DIFFRACTION (1.7 Å)
Cite:	Strategies toward improving the brain penetration of macrocyclic tertiary carbinamine BACE-1 inhibitors. Bioorg.Med.Chem.Lett., 17, 2007

Crystal structure of human Beta Secretase complexed with I21
Descriptor:	2-[(5R)-5-amino-5-methyl-4,16-dioxo-14-phenyl-3-oxa-15-azatricyclo[15.3.1.1~7,11~]docosa-1(21),7(22),8,10,12,14,17,19-octaen-19-yl]benzonitrile, Beta-secretase 1
Authors:	Munshi, S.
Deposit date:	2007-08-16
Release date:	2008-04-29
Last modified:	2023-08-30
Method:	X-RAY DIFFRACTION (1.8 Å)
Cite:	Strategies toward improving the brain penetration of macrocyclic tertiary carbinamine BACE-1 inhibitors. Bioorg.Med.Chem.Lett., 17, 2007