Author results

1CF4
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CDC42/ACK GTPASE-BINDING DOMAIN COMPLEX
Descriptor:PROTEIN (CDC42 HOMOLOG), PROTEIN (ACTIVATED P21CDC42HS KINASE), MAGNESIUM ION, ...
Authors:Mott, H.R., Owen, D., Nietlispach, D., Lowe, P.N., Lim, L., Laue, E.D.
Deposit date:1999-03-23
Release date:1999-06-18
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of the small G protein Cdc42 bound to the GTPase-binding domain of ACK.
Nature, 399, 1999
1E0A
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CDC42 COMPLEXED WITH THE GTPASE BINDING DOMAIN OF P21 ACTIVATED KINASE
Descriptor:G25K GTP-BINDING PROTEIN, PLACENTAL ISOFORM (GP), CDC42 HOMOLOG, ...
Authors:Morreale, A., Venkatesan, M., Mott, H.R., Owen, D., Nietlispach, D., Lowe, P.N., Laue, E.D.
Deposit date:2000-03-16
Release date:2000-04-18
Last modified:2014-02-05
Method:SOLUTION NMR
Cite:Solution Structure of Cdc42 Bound to the Gtpase Binding Domian of Pak
Nat.Struct.Biol., 7, 2000
1HK6
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RAL BINDING DOMAIN FROM SEC5
Descriptor:EXOCYST COMPLEX COMPONENT SEC5
Authors:Mott, H.R., Nietlispach, D., Hopkins, L.J., Mirey, G., Camonis, J.H., Owen, D.
Deposit date:2003-03-05
Release date:2003-03-13
Last modified:2018-03-28
Method:SOLUTION NMR
Cite:Structure of the GTPase-binding domain of Sec5 and elucidation of its Ral binding site.
J. Biol. Chem., 278, 2003
1S4Z
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HP1 CHROMO SHADOW DOMAIN IN COMPLEX WITH PXVXL MOTIF OF CAF-1
Descriptor:Chromobox protein homolog 1, Chromatin assembly factor 1 subunit A
Authors:Thiru, A., Nietlispach, D., Mott, H.R., Okuwaki, M., Lyon, D., Nielsen, P.R., Hirshberg, M., Verreault, A., Murzina, N.V., Laue, E.D.
Deposit date:2004-01-19
Release date:2004-03-23
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural basis of HP1/PXVXL motif peptide interactions and HP1 localisation to heterochromatin.
Embo J., 23, 2004
1UQV
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SAM DOMAIN FROM STE50P
Descriptor:STE50 PROTEIN
Authors:Grimshaw, S.J., Mott, H.R., Stott, K.M., Nielsen, P.R., Evetts, K.A., Hopkins, L.J., Nietlispach, D., Owen, D.
Deposit date:2003-10-20
Release date:2003-10-30
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of the Sterile {Alpha} Motif (Sam) Domain of the Saccharomyces Cerevisiae Mitogen-Activated Protein Kinase Pathway-Modulating Protein Ste50 and Analysis of its Interaction with the Ste11 Sam
J.Biol.Chem., 279, 2004
1URF
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HR1B DOMAIN FROM PRK1
Descriptor:PROTEIN KINASE C-LIKE 1
Authors:Owen, D., Lowe, P.N., Nietlispach, D., Brosnan, C.E., Chirgadze, D.Y., Parker, P.J., Blundell, T.L., Mott, H.R.
Deposit date:2003-10-29
Release date:2003-11-06
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Molecular Dissection of the Interaction between the Small G Proteins Rac1 and Rhoa and Protein Kinase C-Related Kinase 1 (Prk1)
J.Biol.Chem., 278, 2003
1ZSG
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BETA PIX-SH3 COMPLEXED WITH AN ATYPICAL PEPTIDE FROM ALPHA-PAK
Descriptor:Rho guanine nucleotide exchange factor 7, Serine/threonine-protein kinase PAK 1
Authors:Mott, H.R., Nietlispach, D., Evetts, K.A., Owen, D.
Deposit date:2005-05-24
Release date:2005-08-30
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural Analysis of the SH3 Domain of beta-PIX and Its Interaction with alpha-p21 Activated Kinase (PAK)
Biochemistry, 44, 2005
2K9A
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THE SOLUTION STRUCTURE OF THE ARL2 EFFECTOR, BART
Descriptor:ADP-ribosylation factor-like protein 2-binding protein
Authors:Bailey, L.K., Campbell, L.J., Evetts, K.A., Littlefield, K., Rajendra, E., Nietlispach, D., Owen, D., Mott, H.R.
Deposit date:2008-10-06
Release date:2008-11-11
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The Structure of Binder of Arl2 (BART) Reveals a Novel G Protein Binding Domain: IMPLICATIONS FOR FUNCTION.
J.Biol.Chem., 284, 2009
2KE5
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SOLUTION STRUCTURE AND DYNAMICS OF THE SMALL GTPASE RALB IN ITS ACTIVE CONFORMATION: SIGNIFICANCE FOR EFFECTOR PROTEIN BINDING
Descriptor:Ras-related protein Ral-B, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, MAGNESIUM ION
Authors:Fenwick, R., Prasannan, S., Campbell, L.J., Nietlispach, D., Evetts, K.A., Camonis, J., Mott, H.R., Owen, D.
Deposit date:2009-01-23
Release date:2009-02-17
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure and dynamics of the small GTPase RalB in its active conformation: significance for effector protein binding
Biochemistry, 48, 2009
2KWH
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RAL BINDING DOMAIN OF RLIP76 (RALBP1)
Descriptor:RalA-binding protein 1
Authors:Fenwick, R.B., Campbell, L.J., Rajasekar, K., Prasannan, S., Nietlispach, D., Camonis, J., Owen, D., Mott, H.R.
Deposit date:2010-04-12
Release date:2010-09-01
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The RalB-RLIP76 complex reveals a novel mode of ral-effector interaction
Structure, 18, 2010
2KWI
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RALB-RLIP76 (RALBP1) COMPLEX
Descriptor:Ras-related protein Ral-B, RalA-binding protein 1, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Fenwick, R.B., Campbell, L.J., Rajasekar, K., Prasannan, S., Nietlispach, D., Camonis, J., Owen, D., Mott, H.R.
Deposit date:2010-04-12
Release date:2010-09-01
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The RalB-RLIP76 complex reveals a novel mode of ral-effector interaction
Structure, 18, 2010
2MBG
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RLIP76 (GAP-GBD)
Descriptor:RalA-binding protein 1
Authors:Rajasekar, K.V., Campbell, L.J., Nietlispach, D., Owen, D., Mott, H.R.
Deposit date:2013-07-30
Release date:2013-12-04
Last modified:2013-12-25
Method:SOLUTION NMR
Cite:The Structure of the RLIP76 RhoGAP-Ral Binding Domain Dyad: Fixed Position of the Domains Leads to Dual Engagement of Small G Proteins at the Membrane.
Structure, 21, 2013
2RMK
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RAC1/PRK1 COMPLEX
Descriptor:Ras-related C3 botulinum toxin substrate 1, Serine/threonine-protein kinase N1, MAGNESIUM ION, ...
Authors:Modha, R., Campbell, L.J., Nietlispach, D., Buhecha, H.R., Owen, D., Mott, H.R.
Deposit date:2007-10-25
Release date:2007-11-13
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The Rac1 Polybasic Region Is Required for Interaction with Its Effector PRK1
J.Biol.Chem., 283, 2008
5FRG
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THE NMR STRUCTURE OF THE CDC42-INTERACTING REGION OF TOCA1
Descriptor:FORMIN-BINDING PROTEIN 1-LIKE
Authors:Watson, J.R., Nietlispach, D., Owen, D., Mott, H.R.
Deposit date:2015-12-17
Release date:2016-05-04
Last modified:2016-07-06
Method:SOLUTION NMR
Cite:Investigation of the Interaction between Cdc42 and its Effector Toca1: Handover of Cdc42 to the Actin Regulator N-Wasp is Facilitated by Differential Binding Affinities.
J.Biol.Chem., 291, 2016
1DZ1
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MOUSE HP1 (M31) C TERMINAL (SHADOW CHROMO) DOMAIN
Descriptor:MODIFIER 1 PROTEIN
Authors:Brasher, S.V., Smith, B.O., Fogh, R.H., Nietlispach, D., Thiru, A., Nielsen, P.R., Broadhurst, R.W., Ball, L.J., Murzina, N., Laue, E.D.
Deposit date:2000-02-11
Release date:2000-04-09
Last modified:2018-03-07
Method:SOLUTION NMR
Cite:The Structure of Mouse Hp1 Suggests a Unique Mode of Single Peptide Recognition by the Shadow Chromo Domain Dimer
Embo J., 19, 2000
1GUW
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STRUCTURE OF THE CHROMODOMAIN FROM MOUSE HP1BETA IN COMPLEX WITH THE LYSINE 9-METHYL HISTONE H3 N-TERMINAL PEPTIDE, NMR, 25 STRUCTURES
Descriptor:CHROMOBOX PROTEIN HOMOLOG 1, HISTONE H3.1
Authors:Nielsen, P.R., Nietlispach, D., Mott, H.R., Callaghan, J.M., Bannister, A., Kouzarides, T., Murzin, A.G., Murzina, N.V., Laue, E.D.
Deposit date:2002-02-01
Release date:2002-03-12
Last modified:2018-01-17
Method:SOLUTION NMR
Cite:Structure of the Hp1 Chromodomain Bound to Histone H3 Methylated at Lysine 9
Nature, 416, 2002
1H8B
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EF-HANDS 3,4 FROM ALPHA-ACTININ / Z-REPEAT 7 FROM TITIN
Descriptor:ALPHA-ACTININ 2, SKELETAL MUSCLE ISOFORM, TITIN
Authors:Atkinson, R.A., Joseph, C., Kelly, G., Muskett, F.W., Frenkiel, T.A., Nietlispach, D., Pastore, A.
Deposit date:2001-02-01
Release date:2001-08-30
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Ca2+-Independent Binding of an EF-Hand Domain to a Novel Motif in the Alpha-Actinin-Titin Complex
Nat.Struct.Biol., 8, 2001
1PZQ
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STRUCTURE OF FUSED DOCKING DOMAINS FROM THE ERYTHROMYCIN POLYKETIDE SYNTHASE (DEBS), A MODEL FOR THE INTERACTION BETWEEN DEBS 2 AND DEBS 3: THE A DOMAIN
Descriptor:Erythronolide synthase
Authors:Broadhurst, R.W., Nietlispach, D., Wheatcroft, M.P., Leadlay, P.F., Weissman, K.J.
Deposit date:2003-07-14
Release date:2004-02-24
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The structure of docking domains in modular polyketide synthases.
Chem.Biol., 10, 2003
1PZR
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STRUCTURE OF FUSED DOCKING DOMAINS FROM THE ERYTHROMYCIN POLYKETIDE SYNTHASE (DEBS), A MODEL FOR THE INTERACTION BETWEEN DEBS2 AND DEBS3: THE B DOMAIN
Descriptor:Erythronolide synthase
Authors:Broadhurst, R.W., Nietlispach, D., Wheatcroft, M.P., Leadlay, P.F., Weissman, K.J.
Deposit date:2003-07-14
Release date:2004-02-24
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The structure of docking domains in modular polyketide synthases.
Chem.Biol., 10, 2003
1XU6
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STRUCTURE OF THE C-TERMINAL DOMAIN FROM TRYPANOSOMA BRUCEI VARIANT SURFACE GLYCOPROTEIN MITAT1.2
Descriptor:Variant surface glycoprotein MITAT 1.2
Authors:Chattopadhyay, A., Jones, N.G., Nietlispach, D., Nielsen, P.R., Voorheis, H.P., Mott, H.R., Carrington, M.
Deposit date:2004-10-25
Release date:2004-11-30
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of the C-terminal domain from Trypanosoma brucei variant surface glycoprotein MITat1.2
J.Biol.Chem., 280, 2004
2BL5
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SOLUTION STRUCTURE OF THE KH-QUA2 REGION OF THE XENOPUS STAR-GSG QUAKING PROTEIN.
Descriptor:MGC83862 PROTEIN
Authors:Maguire, M.L., Guler-Gane, G., Nietlispach, D., Raine, A.R.C., Zorn, A.M., Standart, N., Broadhurst, R.W.
Deposit date:2005-03-01
Release date:2005-04-14
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution Structure and Backbone Dynamics of the Kh-Qua2 Region of the Xenopus Star/Gsg Quaking Protein
J.Mol.Biol., 348, 2005
2BUD
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THE SOLUTION STRUCTURE OF THE CHROMO BARREL DOMAIN FROM THE MALES- ABSENT ON THE FIRST (MOF) PROTEIN
Descriptor:MALES-ABSENT ON THE FIRST PROTEIN
Authors:Nielsen, P.R., Nietlispach, D., Buscaino, A., Warner, R.J., Akhtar, A., Murzin, A.G., Murzina, N.V., Laue, E.D.
Deposit date:2005-06-09
Release date:2005-06-24
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of the Chromo Barrel Domain from the Mof Acetyltransferase
J.Biol.Chem., 280, 2005
2JUG
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MULTIENZYME DOCKING IN HYBRID MEGASYNTHETASES
Descriptor:TubC protein
Authors:Richter, C.D., Nietlispach, D., Broadhurst, R.W., Weissman, K.J.
Deposit date:2007-08-24
Release date:2007-12-11
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Multienzyme docking in hybrid megasynthetases
Nat.Chem.Biol., 4, 2008
2JWG
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STRUCTURE OF A GLYCOSYLPHOSPHATIDYLINOSITOL-ANCHORED DOMAIN FROM A TRYPANOSOME VARIANT SURFACE GLYCOPROTEIN
Descriptor:Variant surface glycoprotein ILTAT 1.24
Authors:Jones, N.G., Nietlispach, D., Sharma, R., Burke, D.F., Eyres, I., Mues, M., Mott, H.R., Carrington, M.
Deposit date:2007-10-12
Release date:2007-11-13
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of a Glycosylphosphatidylinositol-anchored Domain from a Trypanosome Variant Surface Glycoprotein
J.Biol.Chem., 283, 2008
2JWH
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STRUCTURE OF A GLYCOSYLPHOSPHATIDYLINOSITOL-ANCHORED DOMAIN FROM A TRYPANOSOME VARIANT SURFACE GLYCOPROTEIN
Descriptor:Variant surface glycoprotein ILTAT 1.24
Authors:Jones, N.G., Nietlispach, D., Sharma, R., Burke, D.F., Eyres, I., Mues, M., Mott, H.R., Carrington, M.
Deposit date:2007-10-12
Release date:2007-11-13
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of a Glycosylphosphatidylinositol-anchored Domain from a Trypanosome Variant Surface Glycoprotein
J.Biol.Chem., 283, 2008
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