Author results

3INK
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UNRAVELING THE STRUCTURE OF INTERLEUKIN-2: REPLY
Descriptor:INTERLEUKIN-2
Authors:Mckay, D.B., Brandhuber, B.J.
Deposit date:1992-12-09
Release date:1993-10-31
Last modified:2013-09-04
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Response.
Science, 257, 1992
4NBO
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HUMAN STEROID RECEPTOR RNA ACTIVATOR PROTEIN CARBOXY-TERMINAL DOMAIN
Descriptor:Steroid receptor RNA activator 1
Authors:Mckay, D.B., Xi, L., Barthel, K.K.B., Cech, T.C.
Deposit date:2013-10-23
Release date:2014-02-05
Last modified:2014-10-08
Method:X-RAY DIFFRACTION (2.807 Å)
Cite:Structure and function of steroid receptor RNA activator protein, the proposed partner of SRA noncoding RNA.
J.Mol.Biol., 426, 2014
1IKP
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PSEUDOMONAS AERUGINOSA EXOTOXIN A, P201Q, W281A MUTANT
Descriptor:EXOTOXIN A, CHLORIDE ION, SODIUM ION
Authors:McKay, D.B., Wedekind, J.E., Trame, C.B.
Deposit date:2001-05-04
Release date:2001-12-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Refined Crystallographic Structure of Pseudomonas aeruginosa Exotoxin A and its Implications for the Molecular Mechanism of Toxicity
J.Mol.Biol., 314, 2001
1IKQ
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PSEUDOMONAS AERUGINOSA EXOTOXIN A, WILD TYPE
Descriptor:EXOTOXIN A, CHLORIDE ION, SODIUM ION
Authors:McKay, D.B., Wedekind, J.E., Trame, C.B.
Deposit date:2001-05-04
Release date:2001-12-12
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Refined Crystallographic Structure of Pseudomonas aeruginosa Exotoxin A and its Implications for the Molecular Mechanism of Toxicity
J.Mol.Biol., 314, 2001
3DBK
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PSEUDOMONAS AERUGINOSA ELASTASE WITH PHOSPHORAMIDON
Descriptor:Elastase, ZINC ION, CALCIUM ION, ...
Authors:McKay, D.B., Overgaard, M.T.
Deposit date:2008-06-01
Release date:2009-07-07
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structure of the Elastase of Pseudomonas aeruginosa Complexed with Phosphoramidon
To be Published
2G0C
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STRUCTURE OF THE RNA BINDING DOMAIN (RESIDUES 404-479) OF THE BACILLUS SUBTILIS YXIN PROTEIN
Descriptor:ATP-dependent RNA helicase dbpA, SULFATE ION
Authors:McKay, D.B.
Deposit date:2006-02-11
Release date:2006-04-18
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The domain of the Bacillus subtilis DEAD-box helicase YxiN that is responsible for specific binding of 23S rRNA has an RNA recognition motif fold.
RNA, 12, 2006
2HJV
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STRUCTURE OF THE SECOND DOMAIN (RESIDUES 207-368) OF THE BACILLUS SUBTILIS YXIN PROTEIN
Descriptor:ATP-dependent RNA helicase dbpA
Authors:McKay, D.B., Caruthers, J.M.
Deposit date:2006-07-02
Release date:2006-12-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structure of the second domain of the Bacillus subtilis DEAD-box RNA helicase YxiN.
Acta Crystallogr.,Sect.F, 62, 2006
2BUP
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T13G MUTANT OF THE ATPASE FRAGMENT OF BOVINE HSC70
Descriptor:Heat shock cognate 71 kDa protein, PHOSPHATE ION, MAGNESIUM ION, ...
Authors:Sousa, M.C., Mckay, D.B.
Deposit date:1998-09-08
Release date:1998-09-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The hydroxyl of threonine 13 of the bovine 70-kDa heat shock cognate protein is essential for transducing the ATP-induced conformational change.
Biochemistry, 37, 1998
1HPM
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HOW POTASSIUM AFFECTS THE ACTIVITY OF THE MOLECULAR CHAPERONE HSC70. II. POTASSIUM BINDS SPECIFICALLY IN THE ATPASE ACTIVE SITE
Descriptor:44K ATPASE FRAGMENT (N-TERMINAL) OF 7O kD HEAT-SHOCK COGNATE PROTEIN, MAGNESIUM ION, PHOSPHATE ION, ...
Authors:Wilbanks, S.M., Mckay, D.B.
Deposit date:1995-03-24
Release date:1995-07-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:How potassium affects the activity of the molecular chaperone Hsc70. II. Potassium binds specifically in the ATPase active site.
J.Biol.Chem., 270, 1995
1KYI
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HSLUV (H. INFLUENZAE)-NLVS VINYL SULFONE INHIBITOR COMPLEX
Descriptor:ATP-dependent hsl protease ATP-binding subunit hslU, ATP-dependent protease hslV, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Sousa, M.C., Kessler, B.M., Overkleeft, H.S., McKay, D.B.
Deposit date:2002-02-04
Release date:2002-05-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal Structure of HslUV Complexed with a Vinyl Sulfone Inhibitor: Corroboration of a Proposed Mechanism of Allosteric Activation of HslV by HslU
J.Mol.Biol., 318, 2002
3HSC
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THREE-DIMENSIONAL STRUCTURE OF THE ATPASE FRAGMENT OF A 70K HEAT-SHOCK COGNATE PROTEIN
Descriptor:HEAT-SHOCK COGNATE 7OKD PROTEIN, MAGNESIUM ION, PHOSPHATE ION, ...
Authors:Flaherty, K.M., Deluca-Flaherty, C.R., Mckay, D.B.
Deposit date:1995-03-24
Release date:1995-07-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Three-dimensional structure of the ATPase fragment of a 70K heat-shock cognate protein.
Nature, 346, 1990
1BA0
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HEAT-SHOCK COGNATE 70KD PROTEIN 44KD ATPASE N-TERMINAL 1NGE 3
Descriptor:HEAT-SHOCK COGNATE 70KD PROTEIN, MAGNESIUM ION, PHOSPHATE ION, ...
Authors:Wilbanks, S.M., Mckay, D.B.
Deposit date:1998-04-21
Release date:1998-07-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural replacement of active site monovalent cations by the epsilon-amino group of lysine in the ATPase fragment of bovine Hsc70.
Biochemistry, 37, 1998
1BA1
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HEAT-SHOCK COGNATE 70KD PROTEIN 44KD ATPASE N-TERMINAL MUTANT WITH CYS 17 REPLACED BY LYS
Descriptor:HEAT-SHOCK COGNATE 70KD PROTEIN, MAGNESIUM ION, SODIUM ION, ...
Authors:Wilbanks, S.M., Mckay, D.B.
Deposit date:1998-04-21
Release date:1998-07-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural replacement of active site monovalent cations by the epsilon-amino group of lysine in the ATPase fragment of bovine Hsc70.
Biochemistry, 37, 1998
1BUP
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T13S MUTANT OF BOVINE 70 KILODALTON HEAT SHOCK PROTEIN
Descriptor:PROTEIN (70 KILODALTON HEAT SHOCK PROTEIN), MAGNESIUM ION, POTASSIUM ION, ...
Authors:Sousa, M.C., Mckay, D.B.
Deposit date:1998-09-03
Release date:1998-09-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The hydroxyl of threonine 13 of the bovine 70-kDa heat shock cognate protein is essential for transducing the ATP-induced conformational change.
Biochemistry, 37, 1998
1HMH
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THREE-DIMENSIONAL STRUCTURE OF A HAMMERHEAD RIBOZYME
Descriptor:HAMMERHEAD RIBOZYME-RNA STRAND, HAMMERHEAD RIBOZYME-DNA STRAND
Authors:Pley, H.W., Flaherty, K.M., McKay, D.B.
Deposit date:1995-06-06
Release date:1995-12-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Three-dimensional structure of a hammerhead ribozyme.
Nature, 372, 1994
1KAX
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70KD HEAT SHOCK COGNATE PROTEIN ATPASE DOMAIN, K71M MUTANT
Descriptor:70KD HEAT SHOCK COGNATE PROTEIN, CHLORIDE ION, MAGNESIUM ION, ...
Authors:O'Brien, M.C., Flaherty, K.M., Mckay, D.B.
Deposit date:1996-04-15
Release date:1996-11-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Lysine 71 of the chaperone protein Hsc70 Is essential for ATP hydrolysis.
J.Biol.Chem., 271, 1996
1KAY
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70KD HEAT SHOCK COGNATE PROTEIN ATPASE DOMAIN, K71A MUTANT
Descriptor:70KD HEAT SHOCK COGNATE PROTEIN, MAGNESIUM ION, CHLORIDE ION, ...
Authors:O'Brien, M.C., Flaherty, K.M., Mckay, D.B.
Deposit date:1996-04-15
Release date:1996-11-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Lysine 71 of the chaperone protein Hsc70 Is essential for ATP hydrolysis.
J.Biol.Chem., 271, 1996
1KAZ
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70KD HEAT SHOCK COGNATE PROTEIN ATPASE DOMAIN, K71E MUTANT
Descriptor:70KD HEAT SHOCK COGNATE PROTEIN, MAGNESIUM ION, POTASSIUM ION, ...
Authors:O'Brien, M.C., Flaherty, K.M., Mckay, D.B.
Deposit date:1996-04-15
Release date:1996-11-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Lysine 71 of the chaperone protein Hsc70 Is essential for ATP hydrolysis.
J.Biol.Chem., 271, 1996
1OFH
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ASYMMETRIC COMPLEX BETWEEN HSLV AND I-DOMAIN DELETED HSLU (H. INFLUENZAE)
Descriptor:ATP-DEPENDENT HSL PROTEASE ATP-BINDING SUBUNIT HSLU, ATP-DEPENDENT PROTEASE HSLV, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Kwon, A.R., Kessler, B.M., Overkleeft, H.S., McKay, D.B.
Deposit date:2003-04-14
Release date:2003-07-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure and Reactivity of an Asymmetric Complex between Hslv and I-Domain Deleted Hslu, a Prokaryotic Homolog of the Eukaryotic Proteasome
J.Mol.Biol., 330, 2003
1OFI
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ASYMMETRIC COMPLEX BETWEEN HSLV AND I-DOMAIN DELETED HSLU (H. INFLUENZAE)
Descriptor:ATP-DEPENDENT HSL PROTEASE ATP-BINDING SUBUNIT HSLU, ATP-DEPENDENT PROTEASE HSLV, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Kwon, A.R., Kessler, B.M., Overkleeft, H.S., McKay, D.B.
Deposit date:2003-04-14
Release date:2003-07-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structure and Reactivity of an Asymmetric Complex between Hslv and I-Domain Deleted Hslu, a Prokaryotic Homolog of the Eukaryotic Proteasome
J.Mol.Biol., 330, 2003
1QQM
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D199S MUTANT OF BOVINE 70 KILODALTON HEAT SHOCK PROTEIN
Descriptor:D199S MUTANT OF BOVINE 70 KILODALTON HEAT SHOCK PROTEIN, MAGNESIUM ION, POTASSIUM ION, ...
Authors:Johnson, E.R., Mckay, D.B.
Deposit date:1999-06-07
Release date:1999-09-15
Last modified:2018-03-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Mapping the role of active site residues for transducing an ATP-induced conformational change in the bovine 70-kDa heat shock cognate protein.
Biochemistry, 38, 1999
1QQN
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D206S MUTANT OF BOVINE 70 KILODALTON HEAT SHOCK PROTEIN
Descriptor:D206S MUTANT OF BOVINE 70 KILODALTON HEAT SHOCK PROTEIN, POTASSIUM ION, CHLORIDE ION, ...
Authors:Johnson, E.R., McKay, D.B.
Deposit date:1999-06-07
Release date:1999-09-15
Last modified:2018-03-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Mapping the role of active site residues for transducing an ATP-induced conformational change in the bovine 70-kDa heat shock cognate protein.
Biochemistry, 38, 1999
1QQO
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E175S MUTANT OF BOVINE 70 KILODALTON HEAT SHOCK PROTEIN
Descriptor:HYDROLASE (ACTING ON ACID ANHYDRIDES), MAGNESIUM ION, CHLORIDE ION, ...
Authors:Johnson, E.R., McKay, D.B.
Deposit date:1999-06-07
Release date:1999-09-15
Last modified:2018-03-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Mapping the role of active site residues for transducing an ATP-induced conformational change in the bovine 70-kDa heat shock cognate protein.
Biochemistry, 38, 1999
1U4G
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ELASTASE OF PSEUDOMONAS AERUGINOSA WITH AN INHIBITOR
Descriptor:Elastase, ZINC ION, CALCIUM ION, ...
Authors:Bitto, E., McKay, D.B.
Deposit date:2004-07-25
Release date:2004-08-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Elastase of Pseudomonas aeruginosa with an inhibitor
To be Published, 2004
1ATR
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THREONINE 204 OF THE CHAPERONE PROTEIN HSC70 INFLUENCES THE STRUCTURE OF THE ACTIVE SITE BUT IS NOT ESSENTIAL FOR ATP HYDROLYSIS
Descriptor:HEAT-SHOCK COGNATE 70 KD PROTEIN, MAGNESIUM ION, PHOSPHATE ION, ...
Authors:O'Brien, M.C., Mckay, D.B.
Deposit date:1993-08-09
Release date:1993-10-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Threonine 204 of the chaperone protein Hsc70 influences the structure of the active site, but is not essential for ATP hydrolysis.
J.Biol.Chem., 268, 1993