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1EAA
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ATOMIC STRUCTURE OF THE CUBIC CORE OF THE PYRUVATE DEHYDROGENASE MULTIENZYME COMPLEX
Descriptor:DIHYDROLIPOYL-TRANSACETYLASE
Authors:Mattevi, A., Hol, W.G.J.
Deposit date:1992-12-16
Release date:1993-10-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystallographic analysis of substrate binding and catalysis in dihydrolipoyl transacetylase (E2p).
Biochemistry, 32, 1993
1EAB
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ATOMIC STRUCTURE OF THE CUBIC CORE OF THE PYRUVATE DEHYDROGENASE MULTIENZYME COMPLEX
Descriptor:DIHYDROLIPOYL-TRANSACETYLASE, COENZYME A, 6,8-DIMERCAPTO-OCTANOIC ACID AMIDE
Authors:Mattevi, A., Hol, W.G.J.
Deposit date:1992-12-16
Release date:1993-10-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystallographic analysis of substrate binding and catalysis in dihydrolipoyl transacetylase (E2p).
Biochemistry, 32, 1993
1EAC
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ATOMIC STRUCTURE OF THE CUBIC CORE OF THE PYRUVATE DEHYDROGENASE MULTIENZYME COMPLEX
Descriptor:DIHYDROLIPOYL-TRANSACETYLASE, OXIDIZED COENZYME A, 2,3-DIHYDROXY-1,4-DITHIOBUTANE
Authors:Mattevi, A., Hol, W.G.J.
Deposit date:1992-12-16
Release date:1993-10-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystallographic analysis of substrate binding and catalysis in dihydrolipoyl transacetylase (E2p).
Biochemistry, 32, 1993
1EAD
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ATOMIC STRUCTURE OF THE CUBIC CORE OF THE PYRUVATE DEHYDROGENASE MULTIENZYME COMPLEX
Descriptor:DIHYDROLIPOYL-TRANSACETYLASE, OXIDIZED COENZYME A
Authors:Mattevi, A., Hol, W.G.J.
Deposit date:1992-12-16
Release date:1993-10-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystallographic analysis of substrate binding and catalysis in dihydrolipoyl transacetylase (E2p).
Biochemistry, 32, 1993
1EAE
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ATOMIC STRUCTURE OF THE CUBIC CORE OF THE PYRUVATE DEHYDROGENASE MULTIENZYME COMPLEX
Descriptor:DIHYDROLIPOYL-TRANSACETYLASE, 6,8-DIMERCAPTO-OCTANOIC ACID AMIDE
Authors:Mattevi, A., Hol, W.G.J.
Deposit date:1992-12-16
Release date:1993-10-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystallographic analysis of substrate binding and catalysis in dihydrolipoyl transacetylase (E2p).
Biochemistry, 32, 1993
1EAF
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ATOMIC STRUCTURE OF THE CUBIC CORE OF THE PYRUVATE DEHYDROGENASE MULTIENZYME COMPLEX
Descriptor:DIHYDROLIPOYL-TRANSACETYLASE, SULFITE ION
Authors:Mattevi, A., Hol, W.G.J.
Deposit date:1992-12-16
Release date:1993-10-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystallographic analysis of substrate binding and catalysis in dihydrolipoyl transacetylase (E2p).
Biochemistry, 32, 1993
1LPF
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THREE-DIMENSIONAL STRUCTURE OF LIPOAMIDE DEHYDROGENASE FROM PSEUDOMONAS FLUORESCENS AT 2.8 ANGSTROMS RESOLUTION. ANALYSIS OF REDOX AND THERMOSTABILITY PROPERTIES
Descriptor:DIHYDROLIPOAMIDE DEHYDROGENASE, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Mattevi, A., Hol, W.
Deposit date:1992-10-26
Release date:1994-01-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Three-dimensional structure of lipoamide dehydrogenase from Pseudomonas fluorescens at 2.8 A resolution. Analysis of redox and thermostability properties.
J.Mol.Biol., 230, 1993
1PKY
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PYRUVATE KINASE FROM E. COLI IN THE T-STATE
Descriptor:PYRUVATE KINASE
Authors:Mattevi, A.
Deposit date:1995-04-27
Release date:1995-12-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of Escherichia coli pyruvate kinase type I: molecular basis of the allosteric transition.
Structure, 3, 1995
1LVL
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THE REFINED STRUCTURE OF PSEUDOMONAS PUTIDA LIPOAMIDE DEHYDROGENASE COMPLEXED WITH NAD+ AT 2.45 ANGSTROMS RESOLUTION
Descriptor:DIHYDROLIPOAMIDE DEHYDROGENASE, FLAVIN-ADENINE DINUCLEOTIDE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Mattevi, A., Hol, W.G.J.
Deposit date:1992-12-16
Release date:1994-01-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:The refined crystal structure of Pseudomonas putida lipoamide dehydrogenase complexed with NAD+ at 2.45 A resolution.
Proteins, 13, 1992
1AHU
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STRUCTURE OF THE OCTAMERIC FLAVOENZYME VANILLYL-ALCOHOL OXIDASE IN COMPLEX WITH P-CRESOL
Descriptor:VANILLYL-ALCOHOL OXIDASE, N5-(4-HYDROXYBENZYL)FLAVIN-ADENINE DINUCLEOTIDE
Authors:Mattevi, A.
Deposit date:1997-04-10
Release date:1997-10-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structures and inhibitor binding in the octameric flavoenzyme vanillyl-alcohol oxidase: the shape of the active-site cavity controls substrate specificity.
Structure, 5, 1997
1AHV
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STRUCTURE OF THE OCTAMERIC FLAVOENZYME VANILLYL-ALCOHOL OXIDASE IN COMPLEX WITH 2-NITRO-P-CRESOL
Descriptor:VANILLYL-ALCOHOL OXIDASE, FLAVIN-ADENINE DINUCLEOTIDE, 2-NITRO-P-CRESOL
Authors:Mattevi, A.
Deposit date:1997-04-10
Release date:1997-10-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal structures and inhibitor binding in the octameric flavoenzyme vanillyl-alcohol oxidase: the shape of the active-site cavity controls substrate specificity.
Structure, 5, 1997
1AHZ
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STRUCTURE OF THE OCTAMERIC FLAVOENZYME VANILLYL-ALCOHOL OXIDASE IN COMPLEX WITH 4-(1-HEPTENYL)PHENOL
Descriptor:VANILLYL-ALCOHOL OXIDASE, CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Mattevi, A.
Deposit date:1997-04-10
Release date:1997-10-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Crystal structures and inhibitor binding in the octameric flavoenzyme vanillyl-alcohol oxidase: the shape of the active-site cavity controls substrate specificity.
Structure, 5, 1997
1CHU
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STRUCTURE OF L-ASPARTATE OXIDASE: IMPLICATIONS FOR THE SUCCINATE DEHYDROGENASE/ FUMARATE REDUCATSE FAMILY
Descriptor:PROTEIN (L-ASPARTATE OXIDASE)
Authors:Mattevi, A.
Deposit date:1999-03-29
Release date:1999-06-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of L-aspartate oxidase: implications for the succinate dehydrogenase/fumarate reductase oxidoreductase family.
Structure Fold.Des., 7, 1999
1VAO
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STRUCTURE OF THE OCTAMERIC FLAVOENZYME VANILLYL-ALCOHOL OXIDASE
Descriptor:VANILLYL-ALCOHOL OXIDASE, ACETATE ION, CHLORIDE ION, ...
Authors:Mattevi, A.
Deposit date:1997-04-10
Release date:1997-10-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structures and inhibitor binding in the octameric flavoenzyme vanillyl-alcohol oxidase: the shape of the active-site cavity controls substrate specificity.
Structure, 5, 1997
2VAO
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STRUCTURE OF THE OCTAMERIC FLAVOENZYME VANILLYL-ALCOHOL OXIDASE IN COMPLEX WITH ISOEUGENOL
Descriptor:VANILLYL-ALCOHOL OXIDASE, FLAVIN-ADENINE DINUCLEOTIDE, 2-methoxy-4-[(1E)-prop-1-en-1-yl]phenol
Authors:Mattevi, A.
Deposit date:1997-04-10
Release date:1997-10-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structures and inhibitor binding in the octameric flavoenzyme vanillyl-alcohol oxidase: the shape of the active-site cavity controls substrate specificity.
Structure, 5, 1997
3LAD
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REFINED CRYSTAL STRUCTURE OF LIPOAMIDE DEHYDROGENASE FROM AZOTOBACTER VINELANDII AT 2.2 ANGSTROMS RESOLUTION. A COMPARISON WITH THE STRUCTURE OF GLUTATHIONE REDUCTASE
Descriptor:DIHYDROLIPOAMIDE DEHYDROGENASE, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Mattevi, A., Schierbeek, A.J., Hol, W.G.J.
Deposit date:1991-12-11
Release date:1994-01-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Refined crystal structure of lipoamide dehydrogenase from Azotobacter vinelandii at 2.2 A resolution. A comparison with the structure of glutathione reductase.
J.Mol.Biol., 220, 1991
1QLT
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STRUCTURE OF THE H422A MUTANT OF THE FLAVOENZYME VANILLYL-ALCOHOL OXIDASE
Descriptor:VANILLYL-ALCOHOL OXIDASE, FLAVIN-ADENINE DINUCLEOTIDE, ACETATE ION
Authors:Mattevi, A., Fraaije, M.
Deposit date:1999-09-16
Release date:1999-09-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Covalent Flavinylation is Essential for Efficient Redox Catalysis in Vanillyl-Alcohol Oxidase.
J.Biol.Chem., 274, 2000
1QLU
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STRUCTURE OF THE H422A MUTANT VANILLYL-ALCOHOL OXIDASE IN COMPLEX WITH ISOEUGENOL
Descriptor:VANILLYL-ALCOHOL OXIDASE, FLAVIN-ADENINE DINUCLEOTIDE, 2-methoxy-4-[(1E)-prop-1-en-1-yl]phenol
Authors:Mattevi, A.
Deposit date:1999-09-16
Release date:1999-09-20
Last modified:2012-09-05
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Covalent Flavinylation is Essential for Efficient Redox Catalysis in Vanillyl-Alcohol Oxidase
J.Biol.Chem., 274, 1999
6GOU
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DEVELOPMENT OF ALKYL GLYCERONE PHOSPHATE SYNTHASE INHIBITORS: COMPLEX WITH INHIBITOR 2I
Descriptor:Alkyldihydroxyacetonephosphate synthase, peroxisomal, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Mattevi, A., Piano, V.
Deposit date:2018-06-04
Release date:2019-01-02
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Development of alkyl glycerone phosphate synthase inhibitors: Structure-activity relationship and effects on ether lipids and epithelial-mesenchymal transition in cancer cells.
Eur J Med Chem, 163, 2018
1KIF
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D-AMINO ACID OXIDASE FROM PIG KIDNEY
Descriptor:D-AMINO ACID OXIDASE, FLAVIN-ADENINE DINUCLEOTIDE, BENZOIC ACID
Authors:Todone, F., Mattevi, A.
Deposit date:1996-01-19
Release date:1996-07-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of D-amino acid oxidase: a case of active site mirror-image convergent evolution with flavocytochrome b2.
Proc.Natl.Acad.Sci.USA, 93, 1996
5LGN
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THIENO[3,2-B]PYRROLE-5-CARBOXAMIDES AS NOVEL REVERSIBLE INHIBITORS OF HISTONE LYSINE DEMETHYLASE KDM1A/LSD1: COMPOUND 19
Descriptor:Lysine-specific histone demethylase 1A, REST corepressor 1, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Mattevi, A., Ciossani, G.
Deposit date:2016-07-07
Release date:2017-02-22
Last modified:2017-03-22
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Thieno[3,2-b]pyrrole-5-carboxamides as New Reversible Inhibitors of Histone Lysine Demethylase KDM1A/LSD1. Part 1: High-Throughput Screening and Preliminary Exploration.
J. Med. Chem., 60, 2017
5LGT
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THIENO[3,2-B]PYRROLE-5-CARBOXAMIDES AS NOVEL REVERSIBLE INHIBITORS OF HISTONE LYSINE DEMETHYLASE KDM1A/LSD1: COMPOUND 15
Descriptor:Lysine-specific histone demethylase 1A, REST corepressor 1, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Mattevi, A., Ciossani, G.
Deposit date:2016-07-08
Release date:2017-02-22
Last modified:2017-03-22
Method:X-RAY DIFFRACTION (3 Å)
Cite:Thieno[3,2-b]pyrrole-5-carboxamides as New Reversible Inhibitors of Histone Lysine Demethylase KDM1A/LSD1. Part 2: Structure-Based Drug Design and Structure-Activity Relationship.
J. Med. Chem., 60, 2017
5LGU
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THIENO[3,2-B]PYRROLE-5-CARBOXAMIDES AS NOVEL REVERSIBLE INHIBITORS OF HISTONE LYSINE DEMETHYLASE KDM1A/LSD1: COMPOUND 34
Descriptor:Lysine-specific histone demethylase 1A, REST corepressor 1, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Mattevi, A., Ciossani, G.
Deposit date:2016-07-08
Release date:2017-02-22
Last modified:2017-03-22
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Thieno[3,2-b]pyrrole-5-carboxamides as New Reversible Inhibitors of Histone Lysine Demethylase KDM1A/LSD1. Part 2: Structure-Based Drug Design and Structure-Activity Relationship.
J. Med. Chem., 60, 2017
1E8F
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STRUCTURE OF THE H61T MUTANT OF THE FLAVOENZYME VANILLYL-ALCOHOL OXIDASE IN THE APO FORM
Descriptor:VANILLYL-ALCOHOL OXIDASE
Authors:Mattevi, A., Fraaije, M.W.
Deposit date:2000-09-20
Release date:2000-09-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural Analysis of Flavinylation in Vanillyl-Alcohol Oxidase
J.Biol.Chem., 275, 2001
1E8H
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STRUCTURE OF THE H61T MUTANT OF THE FLAVOENZYME VANILLYL-ALCOHOL OXIDASE IN THE APO FORM COMPLEXED BY ADP
Descriptor:VANILLYL-ALCOHOL OXIDASE, ADENOSINE-5'-DIPHOSPHATE
Authors:Mattevi, A., Fraaije, M.W.
Deposit date:2000-09-20
Release date:2000-09-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Analysis of Flavinylation in Vanillyl-Alcohol Oxidase
J.Biol.Chem., 275, 2001