4U46
| Crystal structure of an avidin mutant | Descriptor: | Avidin, CHLORIDE ION | Authors: | Agrawal, N, Lehtonen, S, Kahkonen, N, Riihimaki, T, Hytonen, V.P, Kulomaa, M.S, Johnson, M.S, Airenne, T.T. | Deposit date: | 2014-07-23 | Release date: | 2015-08-05 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Artificial Avidin-Based Receptors for a Panel of Small Molecules. Acs Chem.Biol., 11, 2016
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2Y32
| Crystal structure of bradavidin | Descriptor: | BLR5658 PROTEIN | Authors: | Leppiniemi, J, Gronroos, T, Johnson, M.S, Kulomaa, M.S, Hytonen, V.P, Airenne, T.T. | Deposit date: | 2010-12-17 | Release date: | 2011-12-28 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Structure of Bradavidin - C-Terminal Residues Act as Intrinsic Ligands. Plos One, 7, 2012
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4BCS
| Crystal structure of an avidin mutant | Descriptor: | ACETATE ION, BIOTIN, CHIMERIC AVIDIN, ... | Authors: | Airenne, T.T, Niederhauser, B, Hytonen, V.P, Kulomaa, M.S, Johnson, M.S. | Deposit date: | 2012-10-03 | Release date: | 2013-10-16 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | A Novel Chimeric Avidin with Increased Thermal Stability Using DNA Shuffling. Plos One, 9, 2014
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4BBO
| Crystal structure of core-bradavidin | Descriptor: | ACETATE ION, BIOTIN, BLR5658 PROTEIN, ... | Authors: | Airenne, T.T, Johnson, M.S, Maatta, J.A.E, Hytonen, V.H, Kulomaa, M.S. | Deposit date: | 2012-09-27 | Release date: | 2013-10-16 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal Structure of Core-Bradavidin To be Published
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4BJ8
| Zebavidin | Descriptor: | BIOTIN, GLYCEROL, ZEBAVIDIN | Authors: | Airenne, T.T, Parthiban, M, Niederhauser, B, Zmurko, J, Kulomaa, M.S, Hytonen, V.P, Johnson, M.S. | Deposit date: | 2013-04-17 | Release date: | 2013-11-20 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Zebavidin Plos One, 8, 2013
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5LUR
| An avidin mutant | Descriptor: | Avidin, CHLORIDE ION, PROGESTERONE | Authors: | Agrawal, N, Lehtonen, S.I, Riihimaki, T.A, Kulomaa, M.S, Hytonen, V.P, Johnson, M.S, Airenne, T.T. | Deposit date: | 2016-09-09 | Release date: | 2017-09-20 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | An avidin mutant TO BE PUBLISHED
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2C1S
| X-ray structure of biotin binding protein from chicken | Descriptor: | BIOTIN BINDING PROTEIN A, BIOTIN-D-SULFOXIDE | Authors: | Hytonen, V.P, Niskanen, E.A, Maatta, J.A.E, Huuskonen, J, Helttunen, K.J, Halling, K.K, Slotte, J.P, Nordlund, H.R, Rissanen, K, Johnson, M.S, Salminen, T.A, Kulomaa, M.S, Laitinen, O.H, Airenne, T.T. | Deposit date: | 2005-09-19 | Release date: | 2007-02-13 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structure and Characterization of a Novel Chicken Biotin-Binding Protein a (Bbp-A). Bmc Struct.Biol., 7, 2007
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2C1Q
| X-ray structure of biotin binding protein from chicken | Descriptor: | BIOTIN, BIOTIN BINDING PROTEIN A, GLYCEROL | Authors: | Hytonen, V.P, Niskanen, E.A, Maatta, J.A.E, Huuskonen, J, Helttunen, K.J, Halling, K.K, Slotte, J.P, Nordlund, H.R, Rissanen, K, Johnson, M.S, Salminen, T.A, Kulomaa, M.S, Laitinen, O.H, Airenne, T.T. | Deposit date: | 2005-09-19 | Release date: | 2007-02-20 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure and Characterization of a Novel Chicken Biotin-Binding Protein a (Bbp-A). Bmc Struct.Biol., 7, 2007
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2C4I
| Crystal structure of engineered avidin | Descriptor: | AVIDIN, BIOTIN, SULFATE ION | Authors: | Hytonen, V.P, Horha, J, Airenne, T.T, Niskanen, E.A, Helttunen, K, Johnson, M.S, Salminen, T.A, Kulomaa, M.S, Nordlund, H.R. | Deposit date: | 2005-10-19 | Release date: | 2006-07-05 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Controlling Quaternary Structure Assembly: Subunit Interface Engineering and Crystal Structure of Dual Chain Avidin. J.Mol.Biol., 359, 2006
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2UZ2
| Crystal structure of Xenavidin | Descriptor: | ACETATE ION, BIOTIN, XENAVIDIN | Authors: | Helppolainen, S.H, Maatta, J.A.E, Airenne, T.T, Johnson, M.S, Kulomaa, M.S, Nordlund, H.R. | Deposit date: | 2007-04-24 | Release date: | 2008-06-03 | Last modified: | 2017-06-28 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural and Functional Characteristics of Xenavidin, the First Frog Avidin from Xenopus Tropicalis. Bmc Struct.Biol., 9, 2009
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2UYW
| Crystal structure of Xenavidin | Descriptor: | BIOTIN, FORMIC ACID, XENAVIDIN | Authors: | Helppolainen, S.H, Maatta, J.A.E, Airenne, T.T, Johnson, M.S, Kulomaa, M.S, Nordlund, H.R. | Deposit date: | 2007-04-20 | Release date: | 2008-05-27 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural and Functional Characteristics of Xenavidin, the First Frog Avidin from Xenopus Tropicalis. Bmc Struct.Biol., 9, 2009
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1US1
| Crystal structure of human vascular adhesion protein-1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Airenne, T.T, Nymalm, Y, Kidron, H, Soderholm, A, Johnson, M.S, Salminen, T.A. | Deposit date: | 2003-11-17 | Release date: | 2005-02-16 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal Structure of the Human Vascular Adhesion Protein-1: Unique Structural Features with Functional Implications. Protein Sci., 14, 2005
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1F6L
| VARIABLE LIGHT CHAIN DIMER OF ANTI-FERRITIN ANTIBODY | Descriptor: | ANTI-FERRITIN IMMUNOGLOBULIN LIGHT CHAIN | Authors: | Nymalm, Y, Kravchuk, Z, Salminen, T, Chumanevich, A.A, Dubnovitsky, A.P, Kankare, J, Pentikainen, O, Lehtonen, J, Arosio, P, Martsev, S, Johnson, M.S. | Deposit date: | 2000-06-22 | Release date: | 2002-10-23 | Last modified: | 2018-04-04 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Antiferritin VL homodimer binds human spleen ferritin with high specificity J.STRUCT.BIOL., 138, 2002
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1WBI
| AVR2 | Descriptor: | AVIDIN-RELATED PROTEIN 2, BIOTIN, GLYCEROL, ... | Authors: | Airenne, T.T, Hytonen, V.P, Maatta, J.H, Kidron, H, Halling, K.K, Horha, J, Kulomaa, T, Nyholm, T.K.M, Johnson, M.S, Salminen, T.A, Kulomaa, M.S. | Deposit date: | 2004-11-01 | Release date: | 2005-10-12 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Avidin Related Protein 2 Shows Unique Structural and Functional Features Among the Avidin Protein Family. Bmc Biotechnol., 5, 2005
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1PT6
| I domain from human integrin alpha1-beta1 | Descriptor: | GLYCEROL, Integrin alpha-1, MAGNESIUM ION | Authors: | Nymalm, Y, Puranen, J.S, Nyholm, T.K.M, Kapyla, J, Kidron, H, Pentikainen, O, Airenne, T.T, Heino, J, Slotte, J.P, Johnson, M.S, Salminen, T.A. | Deposit date: | 2003-06-23 | Release date: | 2004-04-13 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | Jararhagin-derived RKKH peptides induce structural changes in alpha1I domain of human integrin alpha1beta1. J.Biol.Chem., 279, 2004
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1QCY
| THE CRYSTAL STRUCTURE OF THE I-DOMAIN OF HUMAN INTEGRIN ALPHA1BETA1 | Descriptor: | I-DOMAIN OF INTEGRIN ALPHA1BETA1, MAGNESIUM ION | Authors: | Kankare, J.A, Salminen, T.A, Nymalm, Y, Kaepylae, J, Heino, J, Johnson, M.S. | Deposit date: | 1999-05-12 | Release date: | 2003-09-02 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Jararhagin-derived RKKH Peptides Induce Structural Changes in a1I Domain of Human Integrin a1b1 J.Biol.Chem., 279, 2004
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2JGS
| Circular permutant of avidin | Descriptor: | BIOTIN, CIRCULAR PERMUTANT OF AVIDIN | Authors: | Maatta, J.A.E, Hytonen, V.P, Airenne, T.T, Niskanen, E, Johnson, M.S, Kulomaa, M.S, Nordlund, H.R. | Deposit date: | 2007-02-14 | Release date: | 2008-03-04 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Rational Modification of Ligand-Binding Preference of Avidin by Circular Permutation and Mutagenesis. Chembiochem, 9, 2008
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1VYO
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2JXR
| STRUCTURE OF YEAST PROTEINASE A | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, N-(morpholin-4-ylcarbonyl)-L-phenylalanyl-N-[(1R)-1-(cyclohexylmethyl)-3,3-difluoro-2,2-dihydroxy-4-(methylamino)-4-oxobutyl]-L-norleucinamide, PROTEINASE A, ... | Authors: | Aguilar, C.F, Badasso, M, Dreyer, T, Cronin, N.B, Newman, M.P, Cooper, J.B, Hoover, D.J, Wood, S.P, Johnson, M.S, Blundell, T.L. | Deposit date: | 1997-04-24 | Release date: | 1997-10-29 | Last modified: | 2021-11-03 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | The three-dimensional structure at 2.4 A resolution of glycosylated proteinase A from the lysosome-like vacuole of Saccharomyces cerevisiae. J.Mol.Biol., 267, 1997
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6Q0D
| CRYSTAL STRUCTURE OF LDHA IN COMPLEX WITH COMPOUND NCGC00384414-01 AT 2.05 A RESOLUTION | Descriptor: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 2-{3-[3-(cyclopentylethynyl)-4-fluorophenyl]-5-(cyclopropylmethyl)-4-[(3-fluoro-4-sulfamoylphenyl)methyl]-1H-pyrazol-1-yl}-1,3-thiazole-4-carboxylic acid, GLYCEROL, ... | Authors: | Dranow, D.M, Davies, D.R. | Deposit date: | 2019-08-01 | Release date: | 2020-09-23 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Pyrazole-Based Lactate Dehydrogenase Inhibitors with Optimized Cell Activity and Pharmacokinetic Properties. J.Med.Chem., 63, 2020
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6Q13
| CRYSTAL STRUCTURE OF LDHA IN COMPLEX WITH COMPOUND NCGC00420737-09 AT 2.00 A RESOLUTION | Descriptor: | 1,2-ETHANEDIOL, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 2-[5-(cyclopropylmethyl)-4-[(3-fluoro-4-sulfamoylphenyl)methyl]-3-{3-[(5-methylthiophen-2-yl)ethynyl]phenyl}-1H-pyrazol-1-yl]-1,3-thiazole-4-carboxylic acid, ... | Authors: | Davies, D.R, Dranow, D.M. | Deposit date: | 2019-08-02 | Release date: | 2020-09-23 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Pyrazole-Based Lactate Dehydrogenase Inhibitors with Optimized Cell Activity and Pharmacokinetic Properties. J.Med.Chem., 63, 2020
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5K7K
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6CEQ
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1PU4
| Crystal structure of human vascular adhesion protein-1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Salminen, T.A, Airenne, T.T. | Deposit date: | 2003-06-24 | Release date: | 2005-05-03 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Crystal structure of the human vascular adhesion protein-1: unique structural features with functional implications. Protein Sci., 14, 2005
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1DP5
| THE STRUCTURE OF PROTEINASE A COMPLEXED WITH A IA3 MUTANT INHIBITOR | Descriptor: | PROTEINASE A, PROTEINASE INHIBITOR IA3, beta-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Li, M, Phylip, H.L, Lees, W.E, Winther, J.R, Dunn, B.M, Wlodawer, A, Kay, J, Guschina, A. | Deposit date: | 1999-12-23 | Release date: | 2000-05-03 | Last modified: | 2021-11-03 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The aspartic proteinase from Saccharomyces cerevisiae folds its own inhibitor into a helix. Nat.Struct.Biol., 7, 2000
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