3HRA
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3I75
| Antibody Structure | Descriptor: | Antibody heavy chain, Antibody light chain, CHLORIDE ION, ... | Authors: | Isaacs, N.W, Riboldi-Tunnicliffe, A. | Deposit date: | 2009-07-08 | Release date: | 2010-07-21 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Antibody Structure To be Published
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4INS
| THE STRUCTURE OF 2ZN PIG INSULIN CRYSTALS AT 1.5 ANGSTROMS RESOLUTION | Descriptor: | INSULIN (CHAIN A), INSULIN (CHAIN B), ZINC ION | Authors: | Dodson, G.G, Dodson, E.J, Hodgkin, D.C, Isaacs, N.W, Vijayan, M. | Deposit date: | 1989-07-10 | Release date: | 1990-04-15 | Last modified: | 2017-11-29 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | The structure of 2Zn pig insulin crystals at 1.5 A resolution. Philos.Trans.R.Soc.London,Ser.B, 319, 1988
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1KZU
| INTEGRAL MEMBRANE PERIPHERAL LIGHT HARVESTING COMPLEX FROM RHODOPSEUDOMONAS ACIDOPHILA STRAIN 10050 | Descriptor: | BACTERIOCHLOROPHYLL A, LIGHT HARVESTING PROTEIN B-800/850, Rhodopin b-D-glucoside | Authors: | Cogdell, R.J, Freer, A.A, Isaacs, N.W, Hawthornthwaite-Lawless, A.M, Mcdermott, G, Papiz, M.Z, Prince, S.M. | Deposit date: | 1996-08-31 | Release date: | 1997-04-01 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Apoprotein structure in the LH2 complex from Rhodopseudomonas acidophila strain 10050: modular assembly and protein pigment interactions. J.Mol.Biol., 268, 1997
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1UMX
| PHOTOSYNTHETIC REACTION CENTER MUTANT WITH ARG M267 REPLACED WITH LEU (CHAIN M, R267L) | Descriptor: | BACTERIOCHLOROPHYLL A, BACTERIOPHEOPHYTIN B, FE (III) ION, ... | Authors: | Fyfe, P.K, Isaacs, N.W, Cogdell, R.J, Jones, M.R. | Deposit date: | 2003-09-02 | Release date: | 2004-06-29 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Disruption of a specific molecular interaction with a bound lipid affects the thermal stability of the purple bacterial reaction centre. Biochim.Biophys.Acta, 1608, 2004
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1NKZ
| Crystal structure of LH2 B800-850 from Rps. acidophila at 2.0 Angstrom resolution | Descriptor: | BACTERIOCHLOROPHYLL A, BENZAMIDINE, Light-harvesting protein B-800/850, ... | Authors: | Papiz, M.Z, Prince, S.M, Howard, T, Cogdell, R.J, Isaacs, N.W. | Deposit date: | 2003-01-06 | Release date: | 2003-02-25 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The structure and thermal motion of the B800-850 LH2 complex from Rps. acidophila at 2.0 A resolution and 100K : new structural features and functionally relevant motions. J.Mol.Biol., 326, 2003
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1E6D
| PHOTOSYNTHETIC REACTION CENTER MUTANT WITH TRP M115 REPLACED WITH PHE (CHAIN M, WM115F) PHE M197 REPLACED WITH ARG (CHAIN M, FM197R) | Descriptor: | BACTERIOCHLOROPHYLL A, BACTERIOPHEOPHYTIN A, FE (III) ION, ... | Authors: | Ridge, J.P, Fyfe, P.K, McAuley, K.E, Van Brederode, M.E, Robert, B, Van Grondelle, R, Isaacs, N.W, Cogdell, R.J, Jones, M.R. | Deposit date: | 2000-08-11 | Release date: | 2000-10-30 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | An Examination of How Structural Changes Can Affect the Rate of Electron Transfer in a Mutated Bacterial Photoreaction Centre Biochem.J., 351, 2000
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1E14
| PHOTOSYNTHETIC REACTION CENTER MUTANT WITH PHE M197 REPLACED WITH ARG (CHAIN M, FM197R) AND GLY M203 REPLACED WITH ASP (CHAIN M, GM203D) | Descriptor: | BACTERIOCHLOROPHYLL A, BACTERIOPHEOPHYTIN A, CARDIOLIPIN, ... | Authors: | Fyfe, P.K, Ridge, J.P, McAuley, K.E, Cogdell, R.J, Isaacs, N.W, Jones, M.R. | Deposit date: | 2000-04-18 | Release date: | 2000-06-02 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural Consequences of the Replacement of Glycine M203 with Aspartic Acid in the Reaction Center from Rhodobacter Sphaeroides. Biochemistry, 39, 2000
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1LSP
| THE CRYSTAL STRUCTURE OF A BULGECIN-INHIBITED G-TYPE LYSOZYME FROM THE EGG-WHITE OF THE AUSTRALIAN BLACK SWAN. A COMPARISON OF THE BINDING OF BULGECIN TO THREE MURAMIDASES | Descriptor: | BULGECIN A, LYSOZYME | Authors: | Karlsen, S, Rao, Z.H, Hough, E, Isaacs, N.W. | Deposit date: | 1995-02-09 | Release date: | 1996-01-01 | Last modified: | 2014-03-19 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Structure of a bulgecin-inhibited g-type lysozyme from the egg white of the Australian black swan. A comparison of the binding of bulgecin to three muramidases. Acta Crystallogr.,Sect.D, 52, 1996
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1SBS
| CRYSTAL STRUCTURE OF AN ANTI-HCG FAB | Descriptor: | MONOCLONAL ANTIBODY 3A2, SULFATE ION | Authors: | Fotinou, C, Beauchamp, J, Emsley, P, Dehaan, A, Schielen, W.J.G, Bos, E, Isaacs, N.W. | Deposit date: | 1998-04-08 | Release date: | 1999-04-13 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of an Fab fragment against a C-terminal peptide of hCG at 2.0 A resolution. J.Biol.Chem., 273, 1998
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1NXV
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1NXP
| MicArec pH4.5 | Descriptor: | DNA-binding response regulator, PHOSPHONIC ACID | Authors: | Bent, C.J, Isaacs, N.W, Mitchell, T.J, Riboldi-Tunnicliffe, A. | Deposit date: | 2003-02-11 | Release date: | 2004-02-17 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | Crystal structure of the response regulator 02 receiver domain, the essential YycF two-component system of Streptococcus pneumoniae in both complexed and native states. J.Bacteriol., 186, 2004
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1NXS
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1NXO
| MicArec pH7.0 | Descriptor: | DNA-binding response regulator | Authors: | Bent, C.J, Isaacs, N.W, Mitchell, T.J, Riboldi-Tunnicliffe, A. | Deposit date: | 2003-02-11 | Release date: | 2004-02-17 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Crystal structure of the response regulator 02 receiver domain, the essential YycF two-component system of Streptococcus pneumoniae in both complexed and native states. J.Bacteriol., 186, 2004
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1ZYE
| Crystal structure analysis of Bovine Mitochondrial Peroxiredoxin III | Descriptor: | Thioredoxin-dependent peroxide reductase | Authors: | Cao, Z, Roszak, A.W, Gourlay, L.J, Lindsay, J.G, Isaacs, N.W. | Deposit date: | 2005-06-10 | Release date: | 2005-09-20 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Bovine Mitochondrial Peroxiredoxin III Forms a Two-Ring Catenane Structure, 13, 2005
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2A9P
| Medium Resolution BeF3 bound RR02-rec | Descriptor: | BERYLLIUM TRIFLUORIDE ION, MANGANESE (II) ION, Response regulator | Authors: | Riboldi-Tunnicliffe, A, Isaacs, N.W, Mitchell, T.J. | Deposit date: | 2005-07-12 | Release date: | 2006-09-26 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | Crystal structures of an activated YycF homologue, the essential response regulator from S.pneumoniae in complex with BeF3 and the effect of pH on BeF3 binding, possible phosphate in the active site. TO BE PUBLISHED
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2A9O
| Crystal structures of an activated YycF homologue, the essential response regulator from S.pneumoniae in complex with BeF3 and the effect of pH on BeF3 binding, possible phosphate in the active site | Descriptor: | BERYLLIUM TRIFLUORIDE ION, MANGANESE (II) ION, Response regulator | Authors: | Riboldi-Tunnicliffe, A, Isaacs, N.W, Mitchell, T.J. | Deposit date: | 2005-07-12 | Release date: | 2006-09-26 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Crystal structures of an activated YycF homologue, the essential response regulator from S.pneumoniae in complex with BeF3 and the effect of pH on BeF3 binding, possible phosphate in the active site. TO BE PUBLISHED
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2XE4
| Structure of Oligopeptidase B from Leishmania major | Descriptor: | ANTIPAIN, CHLORIDE ION, GLYCEROL, ... | Authors: | McLuskey, K, Paterson, N.G, Bland, N.D, Mottram, J.C, Isaacs, N.W. | Deposit date: | 2010-05-11 | Release date: | 2010-10-06 | Last modified: | 2019-05-15 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Crystal Structure of Leishmania Major Oligopeptidase B Gives Insight Into the Enzymatic Properties of a Trypanosomatid Virulence Factor. J.Biol.Chem., 285, 2010
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1FV3
| THE HC FRAGMENT OF TETANUS TOXIN COMPLEXED WITH AN ANALOGUE OF ITS GANGLIOSIDE RECEPTOR GT1B | Descriptor: | ETHYL-TRIMETHYL-SILANE, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)-[N-acetyl-alpha-neuraminic acid-(2-8)-N-acetyl-beta-neuraminic acid-(2-3)]beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, PHOSPHATE ION, ... | Authors: | Fotinou, C, Emsley, P, Black, I, Ando, H, Ishida, H, Kiso, M, Sinha, K.A, Fairweather, N.F, Isaacs, N.W. | Deposit date: | 2000-09-18 | Release date: | 2001-09-05 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The crystal structure of tetanus toxin Hc fragment complexed with a synthetic GT1b analogue suggests cross-linking between ganglioside receptors and the toxin. J.Biol.Chem., 276, 2001
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1HRP
| CRYSTAL STRUCTURE OF HUMAN CHORIONIC GONADOTROPIN | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HUMAN CHORIONIC GONADOTROPIN | Authors: | Lapthorn, A.J, Harris, D.C, Isaacs, N.W. | Deposit date: | 1994-08-15 | Release date: | 1994-11-01 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal structure of human chorionic gonadotropin. Nature, 369, 1994
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1FV2
| The Hc fragment of tetanus toxin complexed with an analogue of its ganglioside receptor GT1B | Descriptor: | ETHYL-TRIMETHYL-SILANE, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)-[N-acetyl-alpha-neuraminic acid-(2-8)-N-acetyl-beta-neuraminic acid-(2-3)]beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, PHOSPHATE ION, ... | Authors: | Fotinou, C, Emsley, P, Black, I, Ando, H, Ishida, H, Kiso, M, Sinha, K.A, Fairweather, N.F, Isaacs, N.W. | Deposit date: | 2000-09-18 | Release date: | 2001-09-05 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The crystal structure of tetanus toxin Hc fragment complexed with a synthetic GT1b analogue suggests cross-linking between ganglioside receptors and the toxin. J.Biol.Chem., 276, 2001
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1IJD
| Crystallographic Structure of the LH3 Complex from Rhodopseudomonas acidophila strain 7050 | Descriptor: | BACTERIOCHLOROPHYLL A, LIGHT-HARVESTING PROTEIN B-800/820, ALPHA CHAIN, ... | Authors: | McLuskey, K, Prince, S.M, Cogdell, R.J, Isaacs, N.W. | Deposit date: | 2001-04-25 | Release date: | 2001-10-17 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The crystallographic structure of the B800-820 LH3 light-harvesting complex from the purple bacteria Rhodopseudomonas acidophila strain 7050. Biochemistry, 40, 2001
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1QOV
| PHOTOSYNTHETIC REACTION CENTER MUTANT WITH ALA M260 REPLACED WITH TRP (CHAIN M, A260W) | Descriptor: | BACTERIOCHLOROPHYLL A, BACTERIOPHEOPHYTIN A, CARDIOLIPIN, ... | Authors: | McAuley, K.E, Fyfe, P.K, Ridge, J.P, Isaacs, N.W, Cogdell, R.J, Jones, M.R. | Deposit date: | 1999-11-17 | Release date: | 1999-12-13 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural Details of an Interaction between Cardiolipin and an Integral Membrane Protein Proc.Natl.Acad.Sci.USA, 96, 1999
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3I4D
| Photosynthetic reaction center from rhodobacter sphaeroides 2.4.1 | Descriptor: | (2R,3S)-heptane-1,2,3-triol, 1,4-DIETHYLENE DIOXIDE, BACTERIOCHLOROPHYLL A, ... | Authors: | Fujii, R, Adachi, S, Roszak, A.W, Gardiner, A.T, Cogdell, R.J, Isaacs, N.W, Koshihara, S, Hashimoto, H. | Deposit date: | 2009-07-01 | Release date: | 2010-12-01 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Structure of the carotenoid bound to the reaction centre from Rhodobacter sphaeroides 2.4.1 revealed by time-resolved X-ray crystallography To be Published
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1MPS
| PHOTOSYNTHETIC REACTION CENTER MUTANT WITH PHE M 197 REPLACED WITH ARG AND TYR M 177 REPLACED WITH PHE (CHAIN M, Y177F, F197R) | Descriptor: | BACTERIOCHLOROPHYLL A, BACTERIOPHEOPHYTIN A, FE (II) ION, ... | Authors: | Mcauley-Hecht, K.E, Fyfe, P.K, Ridge, J.P, Prince, S, Hunter, C.N, Isaacs, N.W, Cogdell, R.J, Jones, M.R. | Deposit date: | 1998-03-09 | Release date: | 1998-10-14 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Structural studies of wild-type and mutant reaction centers from an antenna-deficient strain of Rhodobacter sphaeroides: monitoring the optical properties of the complex from bacterial cell to crystal. Biochemistry, 37, 1998
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