2EUY
| Solution structure of the internal loop of human U65 H/ACA snoRNA 3' hairpin | Descriptor: | U65 box H/ACA snoRNA | Authors: | Feigon, J, Khanna, M, Wu, H, Johansson, C, Caizergues-Ferrer, M. | Deposit date: | 2005-10-30 | Release date: | 2006-01-03 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structural study of the H/ACA snoRNP components Nop10p and the 3' hairpin of U65 snoRNA. Rna, 12, 2006
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2QH3
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2QH2
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2QH4
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7SLQ
| Cryo-EM structure of 7SK core RNP with circular RNA | Descriptor: | 7SK snRNA methylphosphate capping enzyme, La-related protein 7, Minimal circular 7SK RNA, ... | Authors: | Yang, Y, Liu, S, Zhou, Z.H, Feigon, J. | Deposit date: | 2021-10-24 | Release date: | 2022-03-30 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structural basis of RNA conformational switching in the transcriptional regulator 7SK RNP. Mol.Cell, 82, 2022
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7SLP
| Cryo-EM structure of 7SK core RNP with linear RNA | Descriptor: | 7SK snRNA methylphosphate capping enzyme, La-related protein 7, Linear 7SK RNA, ... | Authors: | Yang, Y, Liu, S, Zhou, Z.H, Feigon, J. | Deposit date: | 2021-10-24 | Release date: | 2022-03-30 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Structural basis of RNA conformational switching in the transcriptional regulator 7SK RNP. Mol.Cell, 82, 2022
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6D12
| Crystal structure of C-terminal xRRM domain of human Larp7 bound to 7SK stem-loop 4 RNA | Descriptor: | La-related protein 7, human 7SK RNA stem-loop 4 | Authors: | Eichhorn, C.D, Cascio, D, Sawaya, M.R, Feigon, J. | Deposit date: | 2018-04-11 | Release date: | 2018-06-27 | Last modified: | 2020-01-15 | Method: | X-RAY DIFFRACTION (2.205 Å) | Cite: | Structural basis for recognition of human 7SK long noncoding RNA by the La-related protein Larp7. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6TZN
| Structure of S. pombe telomerase accessory protein Pof8 C-terminal domain | Descriptor: | NITRATE ION, Protein pof8 | Authors: | Basu, R.S, Cascio, D, Eichhorn, C.D, Feigon, J. | Deposit date: | 2019-08-12 | Release date: | 2020-08-19 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Structure of S. pombe telomerase protein Pof8 C-terminal domain is an xRRM conserved among LARP7 proteins. Rna Biol., 18, 2021
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8GAP
| Structure of LARP7 protein p65-telomerase RNA complex in telomerase | Descriptor: | Telomerase La-related protein p65, Telomerase RNA, Telomerase associated protein p50, ... | Authors: | Wang, Y, He, Y, Wang, Y, Yang, Y, Singh, M, Eichhorn, C.D, Zhou, Z.H, Feigon, J. | Deposit date: | 2023-02-23 | Release date: | 2023-06-28 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structure of LARP7 Protein p65-telomerase RNA Complex in Telomerase Revealed by Cryo-EM and NMR. J.Mol.Biol., 435, 2023
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2DA8
| SOLUTION STRUCTURE OF A COMPLEX BETWEEN (N-MECYS3,N-MECYS7)TANDEM AND (D(GATATC))2 | Descriptor: | 2-CARBOXYQUINOXALINE, CysMeTANDEM quinoxaline antibiotic, DNA (5'-D(*GP*AP*TP*AP*TP*C)-3') | Authors: | Addess, K.J, Sinsheimer, J.S, Feigon, J. | Deposit date: | 1993-04-09 | Release date: | 1994-01-31 | Last modified: | 2024-08-14 | Method: | SOLUTION NMR | Cite: | Solution Structure of a Complex between [N-Mecys3,N-Mecys7]Tandem and [D(Gatatc)]2. Biochemistry, 32, 1993
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4PBD
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4PCK
| Crystal structure of the P22S mutant of N-terminal CS domain of human Shq1 | Descriptor: | GLYCEROL, Protein SHQ1 homolog | Authors: | Singh, M, Wang, Z, Cascio, D, Feigon, J. | Deposit date: | 2014-04-15 | Release date: | 2015-01-14 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.401 Å) | Cite: | Structure and Interactions of the CS Domain of Human H/ACA RNP Assembly Protein Shq1. J.Mol.Biol., 427, 2015
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1YMO
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5KMZ
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230D
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3EUD
| Structure of the CS domain of the essential H/ACA RNP assembly protein Shq1p | Descriptor: | Protein SHQ1 | Authors: | Singh, M, Cascio, D, Gonzales, F.A, Heckmann, N, Chanfreau, G, Feigon, J. | Deposit date: | 2008-10-09 | Release date: | 2008-11-18 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure and Functional Studies of the CS Domain of the Essential H/ACA Ribonucleoparticle Assembly Protein SHQ1. J.Biol.Chem., 284, 2009
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5DFM
| Structure of Tetrahymena telomerase p19 fused to MBP | Descriptor: | GLYCEROL, Maltose-binding periplasmic protein,Telomerase-associated protein 19, SULFATE ION, ... | Authors: | Chan, H, Cascio, D, Sawaya, M.R, Feigon, J. | Deposit date: | 2015-08-27 | Release date: | 2015-10-28 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.301 Å) | Cite: | Structure of Tetrahymena telomerase reveals previously unknown subunits, functions, and interactions. Science, 350, 2015
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5DFN
| Structure of Tetrahymena Telomerase P45 C-terminal domain | Descriptor: | Telomerase associated protein p45 | Authors: | Chan, H, Cascio, D, Sawaya, M.R, Feigon, J. | Deposit date: | 2015-08-27 | Release date: | 2015-10-28 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.382 Å) | Cite: | Structure of Tetrahymena telomerase reveals previously unknown subunits, functions, and interactions. Science, 350, 2015
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1WAN
| DNA DTA TRIPLEX, NMR, 7 STRUCTURES | Descriptor: | DNA (5'-D(*AP*GP*AP*TP*AP*GP*AP*AP*CP*CP*CP*CP*TP*TP*CP*TP*AP*TP*CP*TP*TP*AP*TP*AP*TP*CP*TP*(D3)P*TP*CP*TP*T)-3') | Authors: | Wang, E, Koshlap, K.M, Gillespie, P, Dervan, P.B, Feigon, J. | Deposit date: | 1996-01-14 | Release date: | 1996-07-11 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of a pyrimidine-purine-pyrimidine triplex containing the sequence-specific intercalating non-natural base D3. J.Mol.Biol., 257, 1996
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6D6V
| CryoEM structure of Tetrahymena telomerase with telomeric DNA at 4.8 Angstrom resolution | Descriptor: | DNA (5'-D(P*GP*TP*TP*GP*GP*GP*GP*TP*TP*GP*GP*GP*GP*TP*TP*GP*GP*GP*G)-3'), RNA (159-MER), Telomerase associated protein p65, ... | Authors: | Jiang, J, Wang, Y, Susac, L, Chan, H, Basu, R, Zhou, Z.H, Feigon, J. | Deposit date: | 2018-04-22 | Release date: | 2018-05-30 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (4.8 Å) | Cite: | Structure of Telomerase with Telomeric DNA. Cell, 173, 2018
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7LMA
| Tetrahymena telomerase T3D2 structure at 3.3 Angstrom | Descriptor: | Telomerase La-related protein p65, Telomerase RNA, Telomerase associated protein p50, ... | Authors: | He, Y, Wang, Y, Liu, B, Helmling, C, Susac, L, Cheng, R, Zhou, Z.H, Feigon, J. | Deposit date: | 2021-02-05 | Release date: | 2021-05-12 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structures of telomerase at several steps of telomere repeat synthesis. Nature, 593, 2021
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7LMB
| Tetrahymena telomerase T5D5 structure at 3.8 Angstrom | Descriptor: | Telomerase La-related protein p65, Telomerase RNA, Telomerase associated protein p50, ... | Authors: | He, Y, Wang, Y, Liu, B, Helmling, C, Susac, L, Cheng, R, Zhou, Z.H, Feigon, J. | Deposit date: | 2021-02-05 | Release date: | 2021-05-12 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structures of telomerase at several steps of telomere repeat synthesis. Nature, 593, 2021
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5KQE
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5KNW
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4EYT
| Crystal structure of the C-terminal domain of Tetrahymena telomerase protein p65 | Descriptor: | SULFATE ION, Telomerase associated protein p65 | Authors: | Singh, M, Wang, Z, Koo, B.-K, Patel, A, Cascio, D, Collins, K, Feigon, J. | Deposit date: | 2012-05-01 | Release date: | 2012-06-20 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural Basis for Telomerase RNA Recognition and RNP Assembly by the Holoenzyme La Family Protein p65. Mol.Cell, 47, 2012
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