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6E67
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STRUCTURE OF BETA2 ADRENERGIC RECEPTOR FUSED TO A GS PEPTIDE
Descriptor:Beta-2 adrenergic receptor,Endolysin,Guanine nucleotide-binding protein G(s) subunit alpha isoforms short,Beta-2 adrenergic receptor chimera, 8-[(1R)-2-{[1,1-dimethyl-2-(2-methylphenyl)ethyl]amino}-1-hydroxyethyl]-5-hydroxy-2H-1,4-benzoxazin-3(4H)-one
Authors:Liu, X., Xu, X., Hilger, D., Tiemann, J., Liu, H., Du, Y., Hirata, K., Sun, X., Guixa-Gonzalez, R., Mathiesen, J., Hildebrand, P., Kobilka, B.
Deposit date:2018-07-24
Release date:2019-06-05
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Structural Insights into the Process of GPCR-G Protein Complex Formation.
Cell, 177, 2019
6EG8
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STRUCTURE OF THE GDP-BOUND GS HETEROTRIMER
Descriptor:Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ...
Authors:Hilger, D., Liu, X., Aschauer, P., Kobilka, B.K.
Deposit date:2018-08-19
Release date:2019-06-05
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Insights into the Process of GPCR-G Protein Complex Formation.
Cell, 177, 2019
6HTB
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YEAST 20S PROTEASOME WITH HUMAN BETA2C (S171G)
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, Proteasome subunit alpha type-4, ...
Authors:Huber, E.M., Groll, M.
Deposit date:2018-10-03
Release date:2019-01-30
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure-Based Design of Inhibitors Selective for Human Proteasome beta 2c or beta 2i Subunits.
J.Med.Chem., 62, 2019
6HTC
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YEAST 20S PROTEASOME WITH HUMAN BETA2C (S171G) IN COMPLEX WITH ONX 0914
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, Proteasome subunit alpha type-4, ...
Authors:Huber, E.M., Groll, M.
Deposit date:2018-10-03
Release date:2019-01-30
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure-Based Design of Inhibitors Selective for Human Proteasome beta 2c or beta 2i Subunits.
J.Med.Chem., 62, 2019
6HTD
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YEAST 20S PROTEASOME WITH HUMAN BETA2C (S171G) IN COMPLEX WITH 4
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, Proteasome subunit alpha type-4, ...
Authors:Huber, E.M., Groll, M.
Deposit date:2018-10-03
Release date:2019-01-30
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure-Based Design of Inhibitors Selective for Human Proteasome beta 2c or beta 2i Subunits.
J.Med.Chem., 62, 2019
6HTP
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YEAST 20S PROTEASOME WITH HUMAN BETA2C (S171G) IN COMPLEX WITH 7
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, Proteasome subunit alpha type-4, ...
Authors:Huber, E.M., Groll, M.
Deposit date:2018-10-04
Release date:2019-01-30
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure-Based Design of Inhibitors Selective for Human Proteasome beta 2c or beta 2i Subunits.
J.Med.Chem., 62, 2019
6HTR
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YEAST 20S PROTEASOME WITH HUMAN BETA2C (S171G) IN COMPLEX WITH 13
Descriptor:PROTEASOME SUBUNIT ALPHA TYPE-2, Proteasome subunit alpha type-3, PROTEASOME SUBUNIT ALPHA TYPE-4, ...
Authors:Huber, E.M., Groll, M.
Deposit date:2018-10-04
Release date:2019-01-30
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure-Based Design of Inhibitors Selective for Human Proteasome beta 2c or beta 2i Subunits.
J.Med.Chem., 62, 2019
6HUB
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YEAST 20S PROTEASOME WITH HUMAN BETA2C (S171G) IN COMPLEX WITH 16
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, Proteasome subunit alpha type-4, ...
Authors:Huber, E.M., Groll, M.
Deposit date:2018-10-05
Release date:2019-01-30
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure-Based Design of Inhibitors Selective for Human Proteasome beta 2c or beta 2i Subunits.
J.Med.Chem., 62, 2019
6HUC
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YEAST 20S PROTEASOME WITH HUMAN BETA2C (S171G) IN COMPLEX WITH 18
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, Proteasome subunit alpha type-4, ...
Authors:Huber, E.M., Groll, M.
Deposit date:2018-10-05
Release date:2019-01-30
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure-Based Design of Inhibitors Selective for Human Proteasome beta 2c or beta 2i Subunits.
J.Med.Chem., 62, 2019
6HUQ
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YEAST 20S PROTEASOME WITH HUMAN BETA2C (S171G) IN COMPLEX WITH 20
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, Proteasome subunit alpha type-4, ...
Authors:Huber, E.M., Groll, M.
Deposit date:2018-10-09
Release date:2019-01-30
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure-Based Design of Inhibitors Selective for Human Proteasome beta 2c or beta 2i Subunits.
J.Med.Chem., 62, 2019
6HUU
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YEAST 20S PROTEASOME WITH HUMAN BETA2C (S171G) IN COMPLEX WITH 29
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, Proteasome subunit alpha type-4, ...
Authors:Huber, E.M., Groll, M.
Deposit date:2018-10-09
Release date:2019-01-30
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure-Based Design of Inhibitors Selective for Human Proteasome beta 2c or beta 2i Subunits.
J.Med.Chem., 62, 2019
6HUV
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YEAST 20S PROTEASOME WITH HUMAN BETA2C (S171G) IN COMPLEX WITH 39
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, Proteasome subunit alpha type-4, ...
Authors:Huber, E.M., Groll, M.
Deposit date:2018-10-09
Release date:2019-01-30
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure-Based Design of Inhibitors Selective for Human Proteasome beta 2c or beta 2i Subunits.
J.Med.Chem., 62, 2019
6HV3
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YEAST 20S PROTEASOME WITH HUMAN BETA2I (1-53)
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, Proteasome subunit alpha type-4, ...
Authors:Huber, E.M., Groll, M.
Deposit date:2018-10-10
Release date:2019-01-30
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure-Based Design of Inhibitors Selective for Human Proteasome beta 2c or beta 2i Subunits.
J.Med.Chem., 62, 2019
6HV4
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YEAST 20S PROTEASOME WITH HUMAN BETA2I (1-53) IN COMPLEX WITH ONX 0914
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, Proteasome subunit alpha type-4, ...
Authors:Huber, E.M., Groll, M.
Deposit date:2018-10-10
Release date:2019-01-30
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure-Based Design of Inhibitors Selective for Human Proteasome beta 2c or beta 2i Subunits.
J.Med.Chem., 62, 2019
6HV5
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YEAST 20S PROTEASOME WITH HUMAN BETA2I (1-53) IN COMPLEX WITH 4
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, Proteasome subunit alpha type-4, ...
Authors:Huber, E.M., Groll, M.
Deposit date:2018-10-10
Release date:2019-01-30
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure-Based Design of Inhibitors Selective for Human Proteasome beta 2c or beta 2i Subunits.
J.Med.Chem., 62, 2019
6HV7
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YEAST 20S PROTEASOME WITH HUMAN BETA2I (1-53) IN COMPLEX WITH 7
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, Proteasome subunit alpha type-4, ...
Authors:Huber, E.M., Groll, M.
Deposit date:2018-10-10
Release date:2019-01-30
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structure-Based Design of Inhibitors Selective for Human Proteasome beta 2c or beta 2i Subunits.
J.Med.Chem., 62, 2019
6HVA
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YEAST 20S PROTEASOME WITH HUMAN BETA2I (1-53) IN COMPLEX WITH 13
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, Proteasome subunit alpha type-4, ...
Authors:Huber, E.M., Groll, M.
Deposit date:2018-10-10
Release date:2019-01-30
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure-Based Design of Inhibitors Selective for Human Proteasome beta 2c or beta 2i Subunits.
J.Med.Chem., 62, 2019
6HVR
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YEAST 20S PROTEASOME WITH HUMAN BETA2I (1-53) IN COMPLEX WITH 16
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, Proteasome subunit alpha type-4, ...
Authors:Huber, E.M., Groll, M.
Deposit date:2018-10-11
Release date:2019-01-30
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure-Based Design of Inhibitors Selective for Human Proteasome beta 2c or beta 2i Subunits.
J.Med.Chem., 62, 2019
6HVS
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YEAST 20S PROTEASOME WITH HUMAN BETA2I (1-53) IN COMPLEX WITH 18
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, Proteasome subunit alpha type-4, ...
Authors:Huber, E.M., Groll, M.
Deposit date:2018-10-11
Release date:2019-01-30
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure-Based Design of Inhibitors Selective for Human Proteasome beta 2c or beta 2i Subunits.
J.Med.Chem., 62, 2019
6HVT
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YEAST 20S PROTEASOME WITH HUMAN BETA2I (1-53) IN COMPLEX WITH 20
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, Proteasome subunit alpha type-4, ...
Authors:Huber, E.M., Groll, M.
Deposit date:2018-10-11
Release date:2019-01-30
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure-Based Design of Inhibitors Selective for Human Proteasome beta 2c or beta 2i Subunits.
J.Med.Chem., 62, 2019
6HVU
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YEAST 20S PROTEASOME WITH HUMAN BETA2I (1-53) IN COMPLEX WITH 29
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, Proteasome subunit alpha type-4, ...
Authors:Huber, E.M., Groll, M.
Deposit date:2018-10-11
Release date:2019-01-30
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure-Based Design of Inhibitors Selective for Human Proteasome beta 2c or beta 2i Subunits.
J.Med.Chem., 62, 2019
6HVV
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YEAST 20S PROTEASOME WITH HUMAN BETA2I (1-53) IN COMPLEX WITH 39
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, Proteasome subunit alpha type-4, ...
Authors:Huber, E.M., Groll, M.
Deposit date:2018-10-11
Release date:2019-01-30
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure-Based Design of Inhibitors Selective for Human Proteasome beta 2c or beta 2i Subunits.
J.Med.Chem., 62, 2019
6HVW
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YEAST 20S PROTEASOME WITH HUMAN BETA2I (1-53) IN COMPLEX WITH 43
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, Proteasome subunit alpha type-4, ...
Authors:Huber, E.M., Groll, M.
Deposit date:2018-10-11
Release date:2019-01-30
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure-Based Design of Inhibitors Selective for Human Proteasome beta 2c or beta 2i Subunits.
J.Med.Chem., 62, 2019
6HVX
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YEAST 20S PROTEASOME IN COMPLEX WITH 4
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, Proteasome subunit alpha type-4, ...
Authors:Huber, E.M., Groll, M.
Deposit date:2018-10-11
Release date:2019-01-30
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure-Based Design of Inhibitors Selective for Human Proteasome beta 2c or beta 2i Subunits.
J.Med.Chem., 62, 2019
6HVY
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YEAST 20S PROTEASOME IN COMPLEX WITH 5 (7- AND 6-MEMBERED RING)
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, Proteasome subunit alpha type-4, ...
Authors:Huber, E.M., Groll, M.
Deposit date:2018-10-11
Release date:2019-01-30
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure-Based Design of Inhibitors Selective for Human Proteasome beta 2c or beta 2i Subunits.
J.Med.Chem., 62, 2019
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