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6RNT
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CRYSTAL STRUCTURE OF RIBONUCLEASE T1 COMPLEXED WITH ADENOSINE 2'-MONOPHOSPHATE AT 1.8-ANGSTROMS RESOLUTION
分子名称:RIBONUCLEASE T1, CALCIUM ION, ADENOSINE-2'-MONOPHOSPHATE
著者Ding, J., Koellner, G., Grunert, H.-P., Saenger, W.
登録日1991-08-20
公開日1993-01-15
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of ribonuclease T1 complexed with adenosine 2'-monophosphate at 1.8-A resolution.
J.Biol.Chem., 266, 1991
7RNT
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CRYSTAL STRUCTURE OF THE TYR45TRP MUTANT OF RIBONUCLEASE T1 IN A COMPLEX WITH 2'-ADENYLIC ACID
分子名称:RIBONUCLEASE T1, CALCIUM ION, ADENOSINE-2'-MONOPHOSPHATE
著者Koellner, G., Grunert, H.-P., Landt, O., Saenger, W.
登録日1991-08-20
公開日1993-01-15
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of the Tyr45Trp mutant of ribonuclease T1 in a complex with 2'-adenylic acid.
Eur.J.Biochem., 201, 1991
8RNT
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STRUCTURE OF RIBONUCLEASE T1 COMPLEXED WITH ZINC(II) AT 1.8 ANGSTROMS RESOLUTION: A ZN2+.6H2O.CARBOXYLATE CLATHRATE
分子名称:RIBONUCLEASE T1, ZINC ION
著者Ding, J., Choe, H.-W., Granzin, J., Saenger, W.
登録日1991-09-23
公開日1993-01-15
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of ribonuclease T1 complexed with zinc(II) at 1.8 A resolution: a Zn2+.6H2O.carboxylate clathrate.
Acta Crystallogr.,Sect.B, 48, 1992
1HNI
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STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN A COMPLEX WITH THE NONNUCLEOSIDE INHIBITOR ALPHA-APA R 95845 AT 2.8 ANGSTROMS RESOLUTION
分子名称:HIV-1 REVERSE TRANSCRIPTASE (SUBUNIT P66), HIV-1 REVERSE TRANSCRIPTASE (SUBUNIT P51), (2-ACETYL-5-METHYLANILINO)(2,6-DIBROMOPHENYL)ACETAMIDE
著者Ding, J., Das, K., Arnold, E.
登録日1995-02-28
公開日1995-06-03
最終更新日2012-02-22
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of HIV-1 reverse transcriptase in a complex with the non-nucleoside inhibitor alpha-APA R 95845 at 2.8 A resolution.
Structure, 3, 1995
1HNV
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STRUCTURE OF HIV-1 RT(SLASH)TIBO R 86183 COMPLEX REVEALS SIMILARITY IN THE BINDING OF DIVERSE NONNUCLEOSIDE INHIBITORS
分子名称:HIV-1 REVERSE TRANSCRIPTASE (SUBUNIT P66), HIV-1 REVERSE TRANSCRIPTASE (SUBUNIT P51), 5-CHLORO-8-METHYL-7-(3-METHYL-BUT-2-ENYL)-6,7,8,9-TETRAHYDRO-2H-2,7,9A-TRIAZA-BENZO[CD]AZULENE-1-THIONE
著者Das, K., Ding, J., Arnold, E.
登録日1995-03-30
公開日1995-07-10
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure of HIV-1 RT/TIBO R 86183 complex reveals similarity in the binding of diverse nonnucleoside inhibitors.
Nat.Struct.Biol., 2, 1995
1WAV
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CRYSTAL STRUCTURE OF FORM B MONOCLINIC CRYSTAL OF INSULIN
分子名称:INSULIN, PHENOL, ZINC ION
著者Liang, D.-C., Ding, J.-H., Chang, W.-R., Wan, Z.-L.
登録日1996-02-28
公開日1997-02-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Molecular replacement study on form-B monoclinic crystal of insulin.
Sci.China, Ser.C: Life Sci., 39, 1996
1AVP
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STRUCTURE OF HUMAN ADENOVIRUS 2 PROTEINASE WITH ITS 11 AMINO ACID COFACTOR
分子名称:ADENOVIRAL PROTEINASE
著者Ding, J., Mcgrath, W.J., Sweet, R.M., Mangel, W.F.
登録日1996-04-04
公開日1997-11-19
最終更新日2018-04-18
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of the human adenovirus proteinase with its 11 amino acid cofactor.
EMBO J., 15, 1996
1TVR
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HIV-1 RT/9-CL TIBO
分子名称:REVERSE TRANSCRIPTASE, 4-CHLORO-8-METHYL-7-(3-METHYL-BUT-2-ENYL)-6,7,8,9-TETRAHYDRO-2H-2,7,9A-TRIAZA-BENZO[CD]AZULENE-1-THIONE
著者Das, K., Ding, J., Hsiou, Y., Arnold, E.
登録日1996-04-16
公開日1997-03-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structures of 8-Cl and 9-Cl TIBO complexed with wild-type HIV-1 RT and 8-Cl TIBO complexed with the Tyr181Cys HIV-1 RT drug-resistant mutant.
J.Mol.Biol., 264, 1996
1DLO
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HUMAN IMMUNODEFICIENCY VIRUS TYPE 1
分子名称:HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 REVERSE TRANSCRIPTASE
著者Hsiou, Y., Ding, J., Das, K., Hughes, S., Arnold, E.
登録日1996-04-17
公開日1996-08-01
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure of unliganded HIV-1 reverse transcriptase at 2.7 A resolution: implications of conformational changes for polymerization and inhibition mechanisms.
Structure, 4, 1996
1UWB
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TYR 181 CYS HIV-1 RT/8-CL TIBO
分子名称:REVERSE TRANSCRIPTASE, 5-CHLORO-8-METHYL-7-(3-METHYL-BUT-2-ENYL)-6,7,8,9-TETRAHYDRO-2H-2,7,9A-TRIAZA-BENZO[CD]AZULENE-1-THIONE
著者Das, K., Ding, J., Hsiou, Y., Arnold, E.
登録日1996-11-21
公開日1997-05-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Crystal structures of 8-Cl and 9-Cl TIBO complexed with wild-type HIV-1 RT and 8-Cl TIBO complexed with the Tyr181Cys HIV-1 RT drug-resistant mutant.
J.Mol.Biol., 264, 1996
1HJA
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LYS 18 VARIANT OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH ALPHA-CHYMOTRYPSIN
分子名称:ALPHA-CHYMOTRYPSIN, OVOMUCOID INHIBITOR
著者Ding, J.-H., James, M.N.G.
登録日1997-07-09
公開日1998-01-14
最終更新日2018-04-04
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structure of Lys18 Variant of Turkey Ovomucoid Inhibitor Third Domain Complexed with Alpha-Chymotrypsin at 2.3 A
To be Published
2WEA
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ACID PROTEINASE (PENICILLOPEPSIN) (E.C.3.4.23.20) COMPLEX WITH PHOSPHONATE INHIBITOR: METHYL[CYCLO-7[(2R)-((N-VALYL) AMINO)-2-(HYDROXYL-(1S)-1-METHYOXYCARBONYL-2-PHENYLETHOXY) PHOSPHINYLOXY-ETHYL]-1-NAPHTHALENEACETAMIDE], SODIUM SALT
分子名称:PENICILLOPEPSIN, ALPHA-D-MANNOSE, SULFATE ION, ...
著者Ding, J., Fraser, M.E., James, M.N.G.
登録日1998-02-03
公開日1998-05-27
最終更新日2018-04-04
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Macrocyclic Inhibitors of Penicillopepsin. II. X-Ray Crystallographic Analyses of Penicillopepsin Complexed with a P3-P1 Macrocyclic Peptidyl Inhibitor and with its Two Acyclic Analogues
J.Am.Chem.Soc., 120, 1998
2WEB
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ACID PROTEINASE (PENICILLOPEPSIN) (E.C.3.4.23.20) COMPLEX WITH PHOSPHONATE INHIBITOR: METHYL(2S)-[1-(((N-FORMYL)-L-VALYL)AMINO-2-(2-NAPHTHYL)ETHYL)HYDROXYPHOSPHINYLOXY]-3-PHENYLPROPANOATE, SODIUM SALT
分子名称:PENICILLOPEPSIN, ALPHA-D-MANNOSE, SULFATE ION, ...
著者Ding, J., Fraser, M.E., James, M.N.G.
登録日1998-02-03
公開日1998-05-27
最終更新日2018-04-04
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Macrocyclic Inhibitors of Penicillopepsin. II. X-Ray Crystallographic Analyses of Penicillopepsin Complexed with a P3-P1 Macrocyclic Peptidyl Inhibitor and with its Two Acyclic Analogues
J.Am.Chem.Soc., 120, 1998
2WEC
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ACID PROTEINASE (PENICILLOPEPSIN) (E.C.3.4.23.20) COMPLEX WITH PHOSPHONATE INHIBITOR: METHYL(2S)-[1-(((N-(1-NAPHTHALENEACETYL))-L-VALYL)AMINOMETHYL)HYDROXY PHOSPHINYLOXY]-3-PHENYLPROPANOATE, SODIUM SALT
分子名称:PENICILLOPEPSIN, ALPHA-D-MANNOSE, SULFATE ION, ...
著者Ding, J., Fraser, M.E., James, M.N.G.
登録日1998-02-03
公開日1998-05-27
最終更新日2018-04-04
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Macrocyclic Inhibitors of Penicillopepsin. II. X-Ray Crystallographic Analyses of Penicillopepsin Complexed with a P3-P1 Macrocyclic Peptidyl Inhibitor and with its Two Acyclic Analogues
J.Am.Chem.Soc., 120, 1998
2WED
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ACID PROTEINASE (PENICILLOPEPSIN) (E.C.3.4.23.20) COMPLEX WITH PHOSPHONATE MACROCYCLIC INHIBITOR:METHYL[CYCLO-7[(2R)-((N-VALYL)AMINO)-2-(HYDROXYL-(1S)-1-METHYOXYCARBONYL-2-PHENYLETHOXY)PHOSPHINYLOXY-ETHYL]-1-NAPHTHALENEACETAMIDE], SODIUM SALT
分子名称:PENICILLOPEPSIN, ALPHA-D-MANNOSE, SULFATE ION, ...
著者Ding, J., Fraser, M.E., James, M.N.G.
登録日1998-02-03
公開日1998-05-27
最終更新日2018-04-04
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Macrocyclic Inhibitors of Penicillopepsin. II. X-Ray Crystallographic Analyses of Penicillopepsin Complexed with a P3-P1 Macrocyclic Peptidyl Inhibitor and with its Two Acyclic Analogues
J.Am.Chem.Soc., 120, 1998
2HMI
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HIV-1 REVERSE TRANSCRIPTASE/FRAGMENT OF FAB 28/DNA COMPLEX
分子名称:DNA (5'-D(*AP*TP*GP*GP*CP*GP*CP*CP*CP*GP*AP*AP*CP*AP*GP*GP*GP*AP*C)-3'), DNA (5'-D(*GP*TP*CP*CP*CP*TP*GP*TP*TP*CP*GP*GP*GP*CP*GP*CP*CP*A)-3'), SUBUNIT OF V-1 REVERSE TRANSCRIPTASE, ...
著者Ding, J., Arnold, E.
登録日1998-04-10
公開日1998-10-14
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure and functional implications of the polymerase active site region in a complex of HIV-1 RT with a double-stranded DNA template-primer and an antibody Fab fragment at 2.8 A resolution.
J.Mol.Biol., 284, 1998
2UP1
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STRUCTURE OF UP1-TELOMERIC DNA COMPLEX
分子名称:DNA (5'-D(P*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*G)-3'), PROTEIN (HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A1)
著者Ding, J., Hayashi, M.K., Krainer, A.R., Xu, R.-M.
登録日1998-07-10
公開日1999-11-10
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of the two-RRM domain of hnRNP A1 (UP1) complexed with single-stranded telomeric DNA.
Genes Dev., 13, 1999
1BQM
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HIV-1 RT/HBY 097
分子名称:REVERSE TRANSCRIPTASE, (S)-4-ISOPROPOXYCARBONYL-6-METHOXY-3-METHYLTHIOMETHYL-3,4-DIHYDROQUINOXALIN-2(1H)-THIONE
著者Hsiou, Y., Das, K., Ding, J., Arnold, E.
登録日1998-08-17
公開日1999-01-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structures of Tyr188Leu mutant and wild-type HIV-1 reverse transcriptase complexed with the non-nucleoside inhibitor HBY 097: inhibitor flexibility is a useful design feature for reducing drug resistance.
J.Mol.Biol., 284, 1998
1BQN
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TYR 188 LEU HIV-1 RT/HBY 097
分子名称:REVERSE TRANSCRIPTASE, (S)-4-ISOPROPOXYCARBONYL-6-METHOXY-3-METHYLTHIOMETHYL-3,4-DIHYDROQUINOXALIN-2(1H)-THIONE
著者Hsiou, Y., Das, K., Ding, J., Arnold, E.
登録日1998-08-17
公開日1999-01-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structures of Tyr188Leu mutant and wild-type HIV-1 reverse transcriptase complexed with the non-nucleoside inhibitor HBY 097: inhibitor flexibility is a useful design feature for reducing drug resistance.
J.Mol.Biol., 284, 1998
1BXO
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ACID PROTEINASE (PENICILLOPEPSIN) (E.C.3.4.23.20) COMPLEX WITH PHOSPHONATE INHIBITOR: METHYL CYCLO[(2S)-2-[[(1R)-1-(N-(L-N-(3-METHYLBUTANOYL)VALYL-L-ASPARTYL)AMINO)-3-METHYLBUT YL] HYDROXYPHOSPHINYLOXY]-3-(3-AMINOMETHYL) PHENYLPROPANOATE
分子名称:PROTEIN (PENICILLOPEPSIN), ALPHA-D-MANNOSE, SULFATE ION, ...
著者Khan, A.R., Parrish, J.C., Fraser, M.E., Smith, W.W., Bartlett, P.A., James, M.N.G.
登録日1998-10-07
公開日1998-10-14
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (0.95 Å)
主引用文献Lowering the entropic barrier for binding conformationally flexible inhibitors to enzymes.
Biochemistry, 37, 1998
1BXQ
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ACID PROTEINASE (PENICILLOPEPSIN) COMPLEX WITH PHOSPHONATE INHIBITOR.
分子名称:PROTEIN (PENICILLOPEPSIN), ALPHA-D-MANNOSE, SULFATE ION, ...
著者Parrish, J.C., Khan, A.R., Fraser, M.E., Smith, W.W., Bartlett, P.A., James, M.N.G.
登録日1998-10-07
公開日1998-10-14
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (1.41 Å)
主引用文献Lowering the entropic barrier for binding conformationally flexible inhibitors to enzymes.
Biochemistry, 37, 1998
1QK6
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SOLUTION STRUCTURE OF HUWENTOXIN-I BY NMR
分子名称:HUWENTOXIN-I
著者Qu, Y., Liang, S., Ding, J., Liu, X., Zhang, R., Gu, X.
登録日1999-07-10
公開日1999-08-20
最終更新日2019-01-16
実験手法SOLUTION NMR
主引用文献Proton Nuclear Magnetic Resonance Studies on Huwentoxin-I from the Venom of the Spider Selenocosmia Huwena:2.Three-Dimensional Structure in Solution
J.Protein Chem., 16, 1997
1QE1
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CRYSTAL STRUCTURE OF 3TC-RESISTANT M184I MUTANT OF HIV-1 REVERSE TRANSCRIPTASE
分子名称:REVERSE TRANSCRIPTASE, SUBUNIT P66, SUBUNIT P51
著者Sarafianos, S.G., Das, K., Ding, J., Hughes, S.H., Arnold, E.
登録日1999-07-12
公開日1999-08-30
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Lamivudine (3TC) resistance in HIV-1 reverse transcriptase involves steric hindrance with beta-branched amino acids.
Proc.Natl.Acad.Sci.USA, 96, 1999
1HPZ
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HUMAN IMMUNODEFICIENCY VIRUS TYPE 1
分子名称:POL POLYPROTEIN, ALPHA-(2,6-DICHLOROPHENYL)-ALPHA-(2-ACETYL-5-METHYLANILINO)ACETAMIDE
著者Ding, J., Hsiou, Y., Arnold, E.
登録日2000-12-13
公開日2001-05-30
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The Lys103Asn mutation of HIV-1 RT: a novel mechanism of drug resistance.
J.Mol.Biol., 309, 2001
1HQE
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HUMAN IMMUNODEFICIENCY VIRUS TYPE 1
分子名称:POL POLYPROTEIN
著者Ding, J., Hsiou, Y., Arnold, E.
登録日2000-12-15
公開日2001-05-30
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The Lys103Asn mutation of HIV-1 RT: a novel mechanism of drug resistance.
J.Mol.Biol., 309, 2001