Author results

8RNT
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STRUCTURE OF RIBONUCLEASE T1 COMPLEXED WITH ZINC(II) AT 1.8 ANGSTROMS RESOLUTION: A ZN2+.6H2O.CARBOXYLATE CLATHRATE
分子名称:RIBONUCLEASE T1, ZINC ION
著者Ding, J., Choe, H.-W., Granzin, J., Saenger, W.
登録日1991-09-23
公開日1993-01-15
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of ribonuclease T1 complexed with zinc(II) at 1.8 A resolution: a Zn2+.6H2O.carboxylate clathrate.
Acta Crystallogr.,Sect.B, 48, 1992
7RNT
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CRYSTAL STRUCTURE OF THE TYR45TRP MUTANT OF RIBONUCLEASE T1 IN A COMPLEX WITH 2'-ADENYLIC ACID
分子名称:RIBONUCLEASE T1, CALCIUM ION, ADENOSINE-2'-MONOPHOSPHATE
著者Koellner, G., Grunert, H.-P., Landt, O., Saenger, W.
登録日1991-08-20
公開日1993-01-15
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of the Tyr45Trp mutant of ribonuclease T1 in a complex with 2'-adenylic acid.
Eur.J.Biochem., 201, 1991
6RNT
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CRYSTAL STRUCTURE OF RIBONUCLEASE T1 COMPLEXED WITH ADENOSINE 2'-MONOPHOSPHATE AT 1.8-ANGSTROMS RESOLUTION
分子名称:RIBONUCLEASE T1, CALCIUM ION, ADENOSINE-2'-MONOPHOSPHATE
著者Ding, J., Koellner, G., Grunert, H.-P., Saenger, W.
登録日1991-08-20
公開日1993-01-15
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of ribonuclease T1 complexed with adenosine 2'-monophosphate at 1.8-A resolution.
J.Biol.Chem., 266, 1991
6JLQ
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CRYSTAL STRUCTURE OF HUMAN USP46-WDR48-WDR20 COMPLEX
分子名称:Ubiquitin carboxyl-terminal hydrolase 46, WD repeat-containing protein 48, WD repeat-containing protein 20,highly similar to WD repeat protein 20,WD repeat-containing protein 20, ...
著者Zhu, H., Zhang, T., Ding, J.
登録日2019-03-06
公開日2019-07-10
実験手法X-RAY DIFFRACTION (3.101 Å)
主引用文献Crystal structure of human USP46-WDR48-WDR20 complex
To Be Published
6E66
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CRYSTAL STRUCTURE OF BACTERIAL N-ACETYLGLUCOSAMINE TRANSFERASE NLEB
分子名称:NleB, 1,2-ETHANEDIOL
著者Yao, Q., Zheng, Y.Q., Shao, F.
登録日2018-07-23
公開日2019-06-05
最終更新日2019-06-19
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural and Functional Insights into Host Death Domains Inactivation by the Bacterial Arginine GlcNAcyltransferase Effector.
Mol.Cell, 74, 2019
6ACI
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CRYSTAL STRUCTURE OF EPEC EFFECTOR NLEB IN COMPLEX WITH FADD DEATH DOMAIN
分子名称:T3SS secreted effector NleB homolog, FAS-associated death domain protein, URIDINE-5'-DIPHOSPHATE, ...
著者Ding, J., Shao, F.
登録日2018-07-26
公開日2019-05-01
最終更新日2019-06-26
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Structural and Functional Insights into Host Death Domains Inactivation by the Bacterial Arginine GlcNAcyltransferase Effector.
Mol.Cell, 74, 2019
6AC5
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CRYSTAL STRUCTURE OF RIPK1 DEATH DOMAIN GLCNACYLATED BY EPEC EFFECTOR NLEB
分子名称:Receptor-interacting serine/threonine-protein kinase 1, N-ACETYL-D-GLUCOSAMINE, SULFATE ION
著者Ding, J., Shao, F.
登録日2018-07-25
公開日2019-05-01
最終更新日2019-06-26
実験手法X-RAY DIFFRACTION (1.451 Å)
主引用文献Structural and Functional Insights into Host Death Domains Inactivation by the Bacterial Arginine GlcNAcyltransferase Effector.
Mol.Cell, 74, 2019
6AC0
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CRYSTAL STRUCTURE OF TRADD DEATH DOMAIN GLCNACYLATED BY EPEC EFFECTOR NLEB
分子名称:Tumor necrosis factor receptor type 1-associated DEATH domain protein, N-ACETYL-D-GLUCOSAMINE
著者Ding, J., Shao, F.
登録日2018-07-24
公開日2019-05-01
最終更新日2019-06-26
実験手法X-RAY DIFFRACTION (1.449 Å)
主引用文献Structural and Functional Insights into Host Death Domains Inactivation by the Bacterial Arginine GlcNAcyltransferase Effector.
Mol.Cell, 74, 2019
5ZVB
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APOBEC3F CHIMERIC CATALYTIC DOMAIN IN COMPLEX WITH DNA(DT9)
分子名称:APEBEC3F/ssDNA-T9, DNA (5'-D(*AP*TP*TP*TP*TP*CP*AP*AP*T)-3'), ZINC ION, ...
著者Cheng, C., Zhang, T.L., Wang, C.X., Lan, W.X., Ding, J.P., Cao, C.Y.
登録日2018-05-09
公開日2018-11-21
最終更新日2018-11-28
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of Cytidine Deaminase Human APOBEC3F Chimeric Catalytic Domain in Complex with DNA
Chin.J.Chem., 36, 2018
5ZVA
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APOBEC3F CHIMERIC CATALYTIC DOMAIN IN COMPLEX WITH DNA(DC9)
分子名称:APEBEC3F/ssDNA-C9, DNA (5'-D(*AP*TP*TP*TP*TP*CP*AP*AP*CP*T)-3'), ZINC ION, ...
著者Cheng, C., Zhang, T.L., Wang, C.X., Lan, W.X., Ding, J.P., Cao, C.Y.
登録日2018-05-09
公開日2018-11-21
最終更新日2018-11-28
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structure of Cytidine Deaminase Human APOBEC3F Chimeric Catalytic Domain in Complex with DNA
Chin.J.Chem., 36, 2018
5Z2C
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CRYSTAL STRUCTURE OF ALPK-1 N-TERMINAL DOMAIN IN COMPLEX WITH ADP-HEPTOSE
分子名称:Alpha-protein kinase 1, [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2S,3S,4S,5S,6R)-6-[(1S)-1,2-bis(oxidanyl)ethyl]-3,4,5-tris(oxidanyl)oxan-2-yl] hydrogen phosphate
著者Ding, J., She, Y., Shao, F.
登録日2018-01-02
公開日2018-08-22
最終更新日2018-09-19
実験手法X-RAY DIFFRACTION (2.594 Å)
主引用文献Alpha-kinase 1 is a cytosolic innate immune receptor for bacterial ADP-heptose.
Nature, 561, 2018
5Z0S
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CRYSTAL STRUCTURE OF FGFR1 KINASE DOMAIN IN COMPLEX WITH A NOVEL INHIBITOR
分子名称:Fibroblast growth factor receptor 1, 1-[(6-chloroimidazo[1,2-b]pyridazin-3-yl)sulfonyl]-6-(1-methyl-1H-pyrazol-4-yl)-1H-pyrazolo[4,3-b]pyridine
著者Liu, Q., Xu, Y.
登録日2017-12-20
公開日2018-12-26
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Structure-Based Discovery of a Series of 5H-Pyrrolo[2,3-b]pyrazine FGFR Kinase Inhibitors
Molecules, 23, 2018
5YVT
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CRYSTAL STRUCTURE OF THE ALPHA GAMMA HETERODIMER OF HUMAN IDH3 IN COMPLEX WITH MG(2+) AND NADH
分子名称:Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial, Isocitrate dehydrogenase [NAD] subunit gamma, ...
著者Ma, T., Ding, J.
登録日2017-11-27
公開日2018-03-14
最終更新日2018-03-28
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Insights into the inhibitory mechanisms of NADH on the alpha gamma heterodimer of human NAD-dependent isocitrate dehydrogenase.
Sci Rep, 8, 2018
5Y7L
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SOLUTION STRUCTURE OF HBETA4 EXTRACELLULAR LOOP OF BK POTASSIUM CHANNEL
分子名称:Calcium-activated potassium channel subunit beta-4
著者Wang, Y., Lan, W., Ding, J., Cao, C.
登録日2017-08-17
公開日2018-08-01
実験手法SOLUTION NMR
主引用文献Solution structure of extracellular loop of human beta 4 subunit of BK channel and its biological implication on ChTX sensitivity.
Sci Rep, 8, 2018
5Y3A
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CRYSTAL STRUCTURE OF RAGULATOR COMPLEX (P18 49-161)
分子名称:Ragulator complex protein LAMTOR1, Ragulator complex protein LAMTOR2, Ragulator complex protein LAMTOR3, ...
著者Zhang, T., Ding, J.
登録日2017-07-28
公開日2017-12-27
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural basis for Ragulator functioning as a scaffold in membrane-anchoring of Rag GTPases and mTORC1.
Nat Commun, 8, 2017
5Y39
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CRYSTAL STRUCTURE OF RAGULATOR COMPLEX (P18 76-145)
分子名称:Ragulator complex protein LAMTOR1, Ragulator complex protein LAMTOR2, Ragulator complex protein LAMTOR3, ...
著者Zhang, T., Ding, J.
登録日2017-07-28
公開日2017-12-06
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Structural basis for Ragulator functioning as a scaffold in membrane-anchoring of Rag GTPases and mTORC1
Nat Commun, 8, 2017
5Y38
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CRYSTAL STRUCTURE OF C7ORF59-HBXIP COMPLEX
分子名称:Ragulator complex protein LAMTOR5, Ragulator complex protein LAMTOR4, SULFATE ION
著者Zhang, T., Ding, J.
登録日2017-07-28
公開日2017-12-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis for Ragulator functioning as a scaffold in membrane-anchoring of Rag GTPases and mTORC1
Nat Commun, 8, 2017
5XYN
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THE CRYSTAL STRUCTURE OF CSM2-PSY3-SHU1-SHU2 COMPLEX FROM BUDDING YEAST
分子名称:Platinum sensitivity protein 3, Chromosome segregation in meiosis protein 2, Suppressor of HU sensitivity involved in recombination protein 1, ...
著者Zhang, S., Zhang, T., Ding, J.
登録日2017-07-09
公開日2017-11-08
最終更新日2017-12-27
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structural basis for the functional role of the Shu complex in homologous recombination.
Nucleic Acids Res., 45, 2017
5XSU
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NOVEL ORALLY EFFICACIOUS INHIBITORS COMPLEXED WITH PARP1
分子名称:Poly [ADP-ribose] polymerase 1, SULFATE ION, 6-fluoranyl-2-(4,5,6,7-tetrahydrofuro[2,3-c]pyridin-2-yl)-1~{H}-benzimidazole-4-carboxamide
著者Liu, Q., Xu, Y.
登録日2017-06-15
公開日2018-04-25
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Design and synthesis of 2-(4,5,6,7-tetrahydrothienopyridin-2-yl)-benzoimidazole carboxamides as novel orally efficacious Poly(ADP-ribose)polymerase (PARP) inhibitors
Eur J Med Chem, 145, 2018
5XST
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NOVEL ORALLY EFFICACIOUS INHIBITORS COMPLEXED WITH PARP1
分子名称:Poly [ADP-ribose] polymerase 1, 6-fluoranyl-2-(4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl)-1~{H}-benzimidazole-4-carboxamide, SULFATE ION
著者Liu, Q., Xu, Y.
登録日2017-06-15
公開日2018-04-25
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Design and synthesis of 2-(4,5,6,7-tetrahydrothienopyridin-2-yl)-benzoimidazole carboxamides as novel orally efficacious Poly(ADP-ribose)polymerase (PARP) inhibitors
Eur J Med Chem, 145, 2018
5XSR
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NOVEL ORALLY EFFICACIOUS INHIBITORS COMPLEXED WITH PARP1
分子名称:Poly [ADP-ribose] polymerase 1, 6-fluoranyl-2-(4,5,6,7-tetrahydrothieno[2,3-c]pyridin-2-yl)-1~{H}-benzimidazole-4-carboxamide, SULFATE ION
著者Liu, Q., Xu, Y.
登録日2017-06-15
公開日2018-04-25
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Design and synthesis of 2-(4,5,6,7-tetrahydrothienopyridin-2-yl)-benzoimidazole carboxamides as novel orally efficacious Poly(ADP-ribose)polymerase (PARP) inhibitors
Eur J Med Chem, 145, 2018
5WYO
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SOLUTION STRUCTURE OF E.COLI HDEA
分子名称:Acid stress chaperone HdeA
著者Yang, C., Hu, Y., Jin, C.
登録日2017-01-14
公開日2017-11-22
実験手法SOLUTION NMR
主引用文献Characterizations of the Interactions between Escherichia coli Periplasmic Chaperone HdeA and Its Native Substrates during Acid Stress
Biochemistry, 56, 2017
5WTT
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STRUCTURE OF THE 093G9 FAB IN COMPLEX WITH THE EPITOPE PEPTIDE
分子名称:Heavy chain of 093G9 Fab, Light chain of 093G9 Fab, Epitope peptide of Cyr61
著者Zhong, C., Hu, K., Shen, J., Ding, J.
登録日2016-12-14
公開日2017-12-20
最終更新日2019-01-02
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Molecular basis for the recognition of CCN1 by monoclonal antibody 093G9.
J. Mol. Recognit., 30, 2017
5O2F
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CRYSTAL STRUCTURE OF NDM-1 IN COMPLEX WITH HYDROLYZED AMPICILLIN - NEW REFINEMENT
分子名称:Metallo-beta-lactamase type 2, ZINC ION, (2R,4S)-2-[(R)-{[(2R)-2-amino-2-phenylacetyl]amino}(carboxy)methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, ...
著者Raczynska, J.E., Shabalin, I.G., Jaskolski, M., Minor, W., Wlodawer, A.
登録日2017-05-20
公開日2018-12-26
最終更新日2019-10-16
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献A close look onto structural models and primary ligands of metallo-beta-lactamases.
Drug Resist. Updat., 40, 2018
5O2E
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CRYSTAL STRUCTURE OF NDM-1 IN COMPLEX WITH HYDROLYZED CEFUROXIME - NEW REFINEMENT
分子名称:Metallo-beta-lactamase type 2, ZINC ION, SULFATE ION, ...
著者Raczynska, J.E., Shabalin, I.G., Jaskolski, M., Minor, W., Wlodawer, A.
登録日2017-05-20
公開日2018-12-26
最終更新日2019-10-16
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献A close look onto structural models and primary ligands of metallo-beta-lactamases.
Drug Resist. Updat., 40, 2018