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Crystal structure of KPT276 in complex with CRM1-Ran-RanBP1
Descriptor:	(2E)-3-{3-[3,5-bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl}-1-(3,3-difluoroazetidin-1-yl)prop-2-en-1-one, 1,2-ETHANEDIOL, CHLORIDE ION, ...
Authors:	Sun, Q, Chook, Y.
Deposit date:	2014-11-05
Release date:	2015-07-15
Last modified:	2023-12-27
Method:	X-RAY DIFFRACTION (1.8 Å)
Cite:	Nuclear export inhibitors avert progression in preclinical models of inflammatory demyelination. Nat.Neurosci., 18, 2015

Crystal structure of KAP beta2-PY-NLS
Descriptor:	RNA-binding protein FUS, Transportin-1
Authors:	Zhang, Z.C, Chook, Y.M.
Deposit date:	2012-05-28
Release date:	2012-07-18
Last modified:	2024-02-28
Method:	X-RAY DIFFRACTION (2.3 Å)
Cite:	Structural and energetic basis of ALS-causing mutations in the atypical proline-tyrosine nuclear localization signal of the Fused in Sarcoma protein (FUS). Proc.Natl.Acad.Sci.USA, 109, 2012