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4C9K
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STRUCTURE OF CAMPHOR AND HYDROXYCAMPHOR BOUND WILD TYPE CYP101D1
Descriptor:CYTOCHROME P450, PROTOPORPHYRIN IX CONTAINING FE, 5-EXO-HYDROXYCAMPHOR, ...
Authors:Batabyal, D., L Poulos, T.
Deposit date:2013-10-02
Release date:2013-12-04
Last modified:2014-02-19
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Crystal Structures and Functional Characterization of Wild-Type Cyp101D1 and its Active Site Mutants.
Biochemistry, 52, 2013
4C9L
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STRUCTURE OF CYANIDE AND CAMPHOR BOUND WILD TYPE CYP101D1
Descriptor:CYTOCHROME P450, PROTOPORPHYRIN IX CONTAINING FE, CAMPHOR, ...
Authors:Batabyal, D., L Poulos, T.
Deposit date:2013-10-02
Release date:2013-12-04
Last modified:2014-02-19
Method:X-RAY DIFFRACTION (1.801 Å)
Cite:Crystal Structures and Functional Characterization of Wild Type and Active Sites Mutants of Cyp101D1.
Biochemistry, 52, 2013
4C9M
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STRUCTURE OF SUBSTRATE FREE, GLYCEROL BOUND WILD TYPE CYP101D1
Descriptor:CYTOCHROME P450, PROTOPORPHYRIN IX CONTAINING FE, GLYCEROL
Authors:Batabyal, D., L Poulos, T.
Deposit date:2013-10-02
Release date:2013-12-04
Last modified:2014-02-19
Method:X-RAY DIFFRACTION (1.801 Å)
Cite:Crystal Structures and Functional Characterization of Wild Type and Active Sites Mutants of Cyp101D1.
Biochemistry, 52, 2013
4C9N
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STRUCTURE OF CAMPHOR AND HYDROXYCAMPHOR BOUND D259N MUTANT OF CYP101D1
Descriptor:CYTOCHROME P450, PROTOPORPHYRIN IX CONTAINING FE, CAMPHOR, ...
Authors:Batabyal, D., L Poulos, T.
Deposit date:2013-10-02
Release date:2013-12-04
Last modified:2014-02-19
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structures and Functional Characterization of Wild Type and Active Sites Mutants of Cyp101D1.
Biochemistry, 52, 2013
4C9O
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STRUCTURE OF CYANIDE AND CAMPHOR BOUND D259N MUTANT OF CYP101D1
Descriptor:CYTOCHROME P450, PROTOPORPHYRIN IX CONTAINING FE, CAMPHOR, ...
Authors:Batabyal, D., L Poulos, T.
Deposit date:2013-10-02
Release date:2013-12-04
Last modified:2015-09-23
Method:X-RAY DIFFRACTION (1.977 Å)
Cite:Crystal Structures and Functional Characterization of Wild-Type Cyp101D1 and its Active Site Mutants.
Biochemistry, 52, 2013
4C9P
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STRUCTURE OF CAMPHOR BOUND T260A MUTANT OF CYP101D1
Descriptor:CYTOCHROME P450, PROTOPORPHYRIN IX CONTAINING FE, CAMPHOR, ...
Authors:Batabyal, D., L Poulos, T.
Deposit date:2013-10-02
Release date:2013-12-04
Last modified:2014-02-19
Method:X-RAY DIFFRACTION (1.799 Å)
Cite:Crystal Structures and Functional Characterization of Wild Type and Active Sites Mutants of Cyp101D1.
Biochemistry, 52, 2013
4L49
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STRUCTURE OF L358A MUTANT OF P450CAM BOUND TO CAMPHOR
Descriptor:Camphor 5-monooxygenase, PROTOPORPHYRIN IX CONTAINING FE, CAMPHOR, ...
Authors:Batabyal, D., Li, H., Poulos, T.L.
Deposit date:2013-06-07
Release date:2013-07-31
Last modified:2013-08-28
Method:X-RAY DIFFRACTION (2.128 Å)
Cite:Synergistic Effects of Mutations in Cytochrome P450cam Designed To Mimic CYP101D1.
Biochemistry, 52, 2013
4L4A
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STRUCTURE OF L358A/K178G MUTANT OF P450CAM BOUND TO CAMPHOR
Descriptor:Camphor 5-monooxygenase, PROTOPORPHYRIN IX CONTAINING FE, CAMPHOR, ...
Authors:Batabyal, D., Li, H., Poulos, T.L.
Deposit date:2013-06-07
Release date:2013-07-31
Last modified:2013-08-28
Method:X-RAY DIFFRACTION (2.103 Å)
Cite:Synergistic Effects of Mutations in Cytochrome P450cam Designed To Mimic CYP101D1.
Biochemistry, 52, 2013
4L4B
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STRUCTURE OF L358A/K178G/D182N MUTANT OF P450CAM BOUND TO CAMPHOR
Descriptor:Camphor 5-monooxygenase, PROTOPORPHYRIN IX CONTAINING FE, CAMPHOR, ...
Authors:Batabyal, D., Li, H., Poulos, T.L.
Deposit date:2013-06-07
Release date:2013-07-31
Last modified:2013-08-28
Method:X-RAY DIFFRACTION (2.099 Å)
Cite:Synergistic Effects of Mutations in Cytochrome P450cam Designed To Mimic CYP101D1.
Biochemistry, 52, 2013
4L4C
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STRUCTURE OF L358P/K178G MUTANT OF P450CAM BOUND TO CAMPHOR
Descriptor:Camphor 5-monooxygenase, PROTOPORPHYRIN IX CONTAINING FE, CAMPHOR, ...
Authors:Batabyal, D., Li, H., Poulos, T.L.
Deposit date:2013-06-07
Release date:2013-07-31
Last modified:2013-08-28
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Synergistic Effects of Mutations in Cytochrome P450cam Designed To Mimic CYP101D1.
Biochemistry, 52, 2013
4L4D
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STRUCTURE OF CYANIDE AND CAMPHOR BOUND P450CAM MUTANT L358A
Descriptor:Camphor 5-monooxygenase, PROTOPORPHYRIN IX CONTAINING FE, CYANIDE ION, ...
Authors:Batabyal, D., Li, H., Poulos, T.L.
Deposit date:2013-06-07
Release date:2013-07-31
Last modified:2013-08-28
Method:X-RAY DIFFRACTION (2.104 Å)
Cite:Synergistic Effects of Mutations in Cytochrome P450cam Designed To Mimic CYP101D1.
Biochemistry, 52, 2013
4L4E
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STRUCTURE OF CYANIDE AND CAMPHOR BOUND P450CAM MUTANT L358A/K178G
Descriptor:Camphor 5-monooxygenase, PROTOPORPHYRIN IX CONTAINING FE, CYANIDE ION, ...
Authors:Batabyal, D., Li, H., Poulos, T.L.
Deposit date:2013-06-07
Release date:2013-07-31
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.261 Å)
Cite:Synergistic Effects of Mutations in Cytochrome P450cam Designed To Mimic CYP101D1.
Biochemistry, 52, 2013
4L4F
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STRUCTURE OF CYANIDE AND CAMPHOR BOUND P450CAM MUTANT L358A/K178G/D182N
Descriptor:Camphor 5-monooxygenase, PROTOPORPHYRIN IX CONTAINING FE, CYANIDE ION, ...
Authors:Batabyal, D., Li, H., Poulos, T.L.
Deposit date:2013-06-07
Release date:2013-07-31
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.294 Å)
Cite:Synergistic Effects of Mutations in Cytochrome P450cam Designed To Mimic CYP101D1.
Biochemistry, 52, 2013
4L4G
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STRUCTURE OF CYANIDE AND CAMPHOR BOUND P450CAM MUTANT L358P/K178G
Descriptor:Camphor 5-monooxygenase, PROTOPORPHYRIN IX CONTAINING FE, CYANIDE ION, ...
Authors:Batabyal, D., Li, H., Poulos, T.L.
Deposit date:2013-06-07
Release date:2013-07-31
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Synergistic Effects of Mutations in Cytochrome P450cam Designed To Mimic CYP101D1.
Biochemistry, 52, 2013
5WK7
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P450CAM MUTANT R186A
Descriptor:Camphor 5-monooxygenase, PROTOPORPHYRIN IX CONTAINING FE, 5-EXO-HYDROXYCAMPHOR, ...
Authors:Batabyal, D., Poulos, T.L.
Deposit date:2017-07-24
Release date:2017-09-06
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (1.983 Å)
Cite:Effect of Redox Partner Binding on Cytochrome P450 Conformational Dynamics.
J. Am. Chem. Soc., 139, 2017
5WK9
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R186AP450CAM WITH CN AND CAMPHOR
Descriptor:Camphor 5-monooxygenase, PROTOPORPHYRIN IX CONTAINING FE, CYANIDE ION, ...
Authors:Poulos, T.L., Batabyal, D.
Deposit date:2017-07-24
Release date:2017-09-06
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (1.983 Å)
Cite:Effect of Redox Partner Binding on Cytochrome P450 Conformational Dynamics.
J. Am. Chem. Soc., 139, 2017
5WMU
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STRUCTURAL INSIGHTS INTO SUBSTRATE AND INHIBITOR BINDING SITES IN HUMAN INDOLEAMINE 2,3-DIOXYGENASE I
Descriptor:Indoleamine 2,3-dioxygenase 1, PROTOPORPHYRIN IX CONTAINING FE, CYANIDE ION, ...
Authors:Lewis-Ballester, A., Yeh, S.R., Pham, K.N., Batabyal, D., Karkashon, S., Bonanno, J.B., Poulos, T.L.
Deposit date:2017-07-31
Release date:2017-12-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural insights into substrate and inhibitor binding sites in human indoleamine 2,3-dioxygenase 1.
Nat Commun, 8, 2017
5WMV
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STRUCTURAL INSIGHTS INTO SUBSTRATE AND INHIBITOR BINDING SITES IN HUMAN INDOLEAMINE 2,3-DIOXYGENASE 1
Descriptor:Indoleamine 2,3-dioxygenase 1, CYANIDE ION, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Lewis-Ballester, A., Yeh, S.R., Pham, K.N., Batabyal, D., Karkashon, S., Bonanno, J.B., Poulos, T.L.
Deposit date:2017-07-31
Release date:2017-12-06
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural insights into substrate and inhibitor binding sites in human indoleamine 2,3-dioxygenase 1.
Nat Commun, 8, 2017
5WMW
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STRUCTURAL INSIGHTS INTO SUBSTRATE AND INHIBITOR BINDING SITES IN HUMAN INDOLEAMINE 2,3-DIOXYGENASE 1
Descriptor:Indoleamine 2,3-dioxygenase 1, PROTOPORPHYRIN IX CONTAINING FE, CYANIDE ION, ...
Authors:Lewis-Ballester, A., Yeh, S.R., Pham, K.N., Batabyal, D., Karkashon, S., Bonanno, J.B., Poulos, T.L.
Deposit date:2017-07-31
Release date:2017-12-06
Method:X-RAY DIFFRACTION (3.03 Å)
Cite:Structural insights into substrate and inhibitor binding sites in human indoleamine 2,3-dioxygenase 1.
Nat Commun, 8, 2017
5WMX
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STRUCTURAL INSIGHTS INTO SUBSTRATE AND INHIBITOR BINDING SITES IN HUMAN INDOLEAMINE 2,3-DIOXYGENASE 1
Descriptor:Indoleamine 2,3-dioxygenase 1, CYANIDE ION, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Lewis-Ballester, A., Yeh, S.R., Pham, K.N., Batabyal, D., Karkashon, S., Bonanno, J.B., Poulos, T.M.
Deposit date:2017-07-31
Release date:2017-12-06
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:Structural insights into substrate and inhibitor binding sites in human indoleamine 2,3-dioxygenase 1.
Nat Commun, 8, 2017
5WN8
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STRUCTURAL INSIGHTS INTO SUBSTRATE AND INHIBITOR BINDING SITES IN HUMAN INDOLEAMINE 2,3-DIOXYGENASE 1
Descriptor:Indoleamine 2,3-dioxygenase 1, PROTOPORPHYRIN IX CONTAINING FE, N-(3-bromo-4-fluorophenyl)-N'-hydroxy-4-{[2-(sulfamoylamino)ethyl]amino}-1,2,5-oxadiazole-3-carboximidamide
Authors:Lewis-Ballester, A., Pham, K.N., Batabyal, D., Karkashon, S., Bonanno, J.B., Poulos, T.L., Yeh, S.R.
Deposit date:2017-07-31
Release date:2017-12-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural insights into substrate and inhibitor binding sites in human indoleamine 2,3-dioxygenase 1.
Nat Commun, 8, 2017
6CXU
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STRUCTURE OF THE S167H MUTANT OF HUMAN INDOLEAMINE 2,3 DIOXYGENASE IN COMPLEX WITH TRYPTOPHAN AND CYANIDE
Descriptor:Indoleamine 2,3-dioxygenase 1, PROTOPORPHYRIN IX CONTAINING FE, CYANIDE ION, ...
Authors:Lewis-Ballester, A., Yeh, S.-R., Karkashon, S., Batabyal, D., Poulos, T.L.
Deposit date:2018-04-04
Release date:2018-06-27
Last modified:2018-07-25
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Inhibition Mechanisms of Human Indoleamine 2,3 Dioxygenase 1.
J. Am. Chem. Soc., 140, 2018
6CXV
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STRUCTURE OF THE S167H MUTANT OF HUMAN INDOLEAMINE 2,3 DIOXYGENASE IN COMPLEX WITH TRYPTOPHAN AND CYANIDE
Descriptor:Indoleamine 2,3-dioxygenase 1, PROTOPORPHYRIN IX CONTAINING FE, CYANIDE ION, ...
Authors:Lewis-Ballester, A., Yeh, S.-R., Karkashon, S., Batabyal, D., Poulos, T.L.
Deposit date:2018-04-04
Release date:2018-06-27
Last modified:2018-07-25
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Inhibition Mechanisms of Human Indoleamine 2,3 Dioxygenase 1.
J. Am. Chem. Soc., 140, 2018
5TI9
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CRYSTAL STRUCTURE OF HUMAN TDO IN COMPLEX WITH TRP AND DIOXYGEN, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET HR6161
Descriptor:Tryptophan 2,3-dioxygenase, OXYGEN MOLECULE, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Forouhar, F., Lewis-Ballester, A., Lew, S., Karkashon, S., Seetharaman, J., Yeh, S.R., Tong, L.
Deposit date:2016-10-01
Release date:2016-10-26
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Molecular basis for catalysis and substrate-mediated cellular stabilization of human tryptophan 2,3-dioxygenase.
Sci Rep, 6, 2016
5TIA
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CRYSTAL STRUCTURE OF HUMAN TDO IN COMPLEX WITH TRP, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET HR6161
Descriptor:Tryptophan 2,3-dioxygenase, PROTOPORPHYRIN IX CONTAINING FE, TRYPTOPHAN
Authors:Forouhar, F., Lewis-Ballester, A., Lew, S., Karkashon, S., Seetharaman, J., Yeh, S.R., Tong, L.
Deposit date:2016-10-01
Release date:2016-10-26
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.441 Å)
Cite:Molecular basis for catalysis and substrate-mediated cellular stabilization of human tryptophan 2,3-dioxygenase.
Sci Rep, 6, 2016