Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
2V6E
DownloadVisualize
BU of 2v6e by Molmil
protelomerase TelK complexed with substrate DNA
Descriptor: PROTELEMORASE, TELRL, VANADATE ION
Authors:Aihara, H, Huang, W.M, Ellenberger, T.
Deposit date:2007-07-17
Release date:2007-10-02
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:An Interlocked Dimer of the Protelomerase Telk Distorts DNA Structure for the Formation of Hairpin Telomeres
Mol.Cell, 27, 2007
1P7D
DownloadVisualize
BU of 1p7d by Molmil
Crystal structure of the Lambda Integrase (residues 75-356) bound to DNA
Descriptor: 26-MER, 5'-D(*CP*AP*AP*TP*GP*CP*CP*AP*AP*CP*TP*TP*T)-3', Integrase
Authors:Aihara, H, Kwon, H.J, Nunes-Duby, S.E, Landy, A, Ellenberger, T.
Deposit date:2003-05-01
Release date:2003-08-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:A Conformational Switch Controls the DNA Cleavage Activity of Lambda Integrase
Mol.Cell, 12, 2003
1B22
DownloadVisualize
BU of 1b22 by Molmil
RAD51 (N-TERMINAL DOMAIN)
Descriptor: DNA REPAIR PROTEIN RAD51
Authors:Aihara, H, Ito, Y, Kurumizaka, H, Yokoyama, S, Shibata, T, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:1998-12-04
Release date:1999-12-03
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:The N-terminal domain of the human Rad51 protein binds DNA: structure and a DNA binding surface as revealed by NMR.
J.Mol.Biol., 290, 1999
1AA3
DownloadVisualize
BU of 1aa3 by Molmil
C-TERMINAL DOMAIN OF THE E. COLI RECA, NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor: RECA
Authors:Aihara, H, Ito, Y, Kurumizaka, H, Terada, T, Yokoyama, S, Shibata, T, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:1997-01-22
Release date:1997-07-23
Last modified:2024-04-10
Method:SOLUTION NMR
Cite:An interaction between a specified surface of the C-terminal domain of RecA protein and double-stranded DNA for homologous pairing.
J.Mol.Biol., 274, 1997
6DFY
DownloadVisualize
BU of 6dfy by Molmil
Remodeled crystal structure of DNA-bound DUX4-HD2
Descriptor: DNA (5'-D(*AP*AP*GP*AP*TP*TP*AP*GP*AP*TP*TP*AP*GP*T)-3'), DNA (5'-D(*TP*TP*CP*TP*AP*AP*TP*CP*TP*AP*AP*TP*CP*A)-3'), Double homeobox protein 4
Authors:Aihara, H, Shi, K.
Deposit date:2018-05-15
Release date:2018-09-05
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.623 Å)
Cite:Comment on structural basis of DUX4/IGH-driven transactivation.
Leukemia, 32, 2018
8VJW
DownloadVisualize
BU of 8vjw by Molmil
Structure of Human Neurolysin in complex with angiotensin I peptide
Descriptor: Angiotensin-1 peptide C-terminal end, Angiotensin-1 peptide N-terminal end, Neurolysin, ...
Authors:Shi, K, Aihara, H.
Deposit date:2024-01-08
Release date:2024-08-21
Method:X-RAY DIFFRACTION (2.491 Å)
Cite:Structural basis of divergent substrate recognition and inhibition of human neurolysin
To Be Published
6P7A
DownloadVisualize
BU of 6p7a by Molmil
CRYSTAL STRUCTURE OF THE FOWLPOX VIRUS HOLLIDAY JUNCTION RESOLVASE
Descriptor: CADMIUM ION, Holliday junction resolvase
Authors:Li, N, Shi, K, Banerjee, S, Rao, T, Aihara, H.
Deposit date:2019-06-05
Release date:2020-04-29
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3.081 Å)
Cite:Structural insights into the promiscuous DNA binding and broad substrate selectivity of fowlpox virus resolvase.
Sci Rep, 10, 2020
6P7B
DownloadVisualize
BU of 6p7b by Molmil
Crystal structure of Fowlpox virus resolvase and substrate Holliday junction DNA complex
Descriptor: DNA (29-MER), Holliday junction resolvase
Authors:Li, N, Shi, K, Rao, T, Banerjee, S, Aihara, H.
Deposit date:2019-06-05
Release date:2020-04-29
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3.317 Å)
Cite:Structural insights into the promiscuous DNA binding and broad substrate selectivity of fowlpox virus resolvase.
Sci Rep, 10, 2020
6VK4
DownloadVisualize
BU of 6vk4 by Molmil
Crystal Structure of Methylosinus trichosporium OB3b Soluble Methane Monooxygenase Hydroxylase and Regulatory Component Complex
Descriptor: 1,2-ETHANEDIOL, BENZOIC ACID, FE (II) ION, ...
Authors:Jones, J.C, Banerjee, R, Shi, K, Aihara, H, Lipscomb, J.D.
Deposit date:2020-01-18
Release date:2020-08-05
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural Studies of theMethylosinus trichosporiumOB3b Soluble Methane Monooxygenase Hydroxylase and Regulatory Component Complex Reveal a Transient Substrate Tunnel.
Biochemistry, 59, 2020
6VK5
DownloadVisualize
BU of 6vk5 by Molmil
Crystal Structure of Methylosinus trichosporium OB3b Soluble Methane Monooxygenase Hydroxylase and Regulatory Component Complex
Descriptor: 1,2-ETHANEDIOL, BENZOIC ACID, CHLORIDE ION, ...
Authors:Jones, J.C, Banerjee, R, Shi, K, Aihara, H, Lipscomb, J.D.
Deposit date:2020-01-18
Release date:2020-08-05
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Structural Studies of theMethylosinus trichosporiumOB3b Soluble Methane Monooxygenase Hydroxylase and Regulatory Component Complex Reveal a Transient Substrate Tunnel.
Biochemistry, 59, 2020
6VK7
DownloadVisualize
BU of 6vk7 by Molmil
Crystal Structure of reduced Methylosinus trichosporium OB3b Soluble Methane Monooxygenase Hydroxylase
Descriptor: FE (III) ION, Methane monooxygenase, Methane monooxygenase component A alpha chain
Authors:Jones, J.C, Banerjee, R, Shi, K, Aihara, H, Lipscomb, J.D.
Deposit date:2020-01-18
Release date:2020-08-05
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:Structural Studies of theMethylosinus trichosporiumOB3b Soluble Methane Monooxygenase Hydroxylase and Regulatory Component Complex Reveal a Transient Substrate Tunnel.
Biochemistry, 59, 2020
6VK8
DownloadVisualize
BU of 6vk8 by Molmil
Crystal Structure of Methylosinus trichosporium OB3b Soluble Methane Monooxygenase Hydroxylase and Regulatory Component Complex with small organic carboxylate at active center
Descriptor: 1,2-ETHANEDIOL, BENZOIC ACID, FE (III) ION, ...
Authors:Jones, J.C, Banerjee, R, Shi, K, Aihara, H, Lipscomb, J.D.
Deposit date:2020-01-18
Release date:2020-08-05
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Structural Studies of theMethylosinus trichosporiumOB3b Soluble Methane Monooxygenase Hydroxylase and Regulatory Component Complex Reveal a Transient Substrate Tunnel.
Biochemistry, 59, 2020
6VK6
DownloadVisualize
BU of 6vk6 by Molmil
Crystal Structure of Methylosinus trichosporium OB3b Soluble Methane Monooxygenase Hydroxylase
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, FE (III) ION, ...
Authors:Jones, J.C, Banerjee, R, Shi, K, Aihara, H, Lipscomb, J.D.
Deposit date:2020-01-18
Release date:2020-08-05
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:Structural Studies of theMethylosinus trichosporiumOB3b Soluble Methane Monooxygenase Hydroxylase and Regulatory Component Complex Reveal a Transient Substrate Tunnel.
Biochemistry, 59, 2020
6VW1
DownloadVisualize
BU of 6vw1 by Molmil
Structure of SARS-CoV-2 chimeric receptor-binding domain complexed with its receptor human ACE2
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Shang, J, Ye, G, Shi, K, Wan, Y.S, Aihara, H, Li, F.
Deposit date:2020-02-18
Release date:2020-03-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:Structural basis of receptor recognition by SARS-CoV-2.
Nature, 581, 2020
6PAK
DownloadVisualize
BU of 6pak by Molmil
Insight into subtilisin E-S7 cleavage pattern based on crystal structure and hydrolysates peptide analysis
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, Subtilisin E
Authors:Tang, H, Shi, K, Aihara, H.
Deposit date:2019-06-11
Release date:2019-10-23
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Enhancing subtilisin thermostability through a modified normalized B-factor analysis and loop-grafting strategy.
J.Biol.Chem., 294, 2019
4NQ3
DownloadVisualize
BU of 4nq3 by Molmil
Crystal structure of cyanuic acid hydrolase from A. caulinodans
Descriptor: BARBITURIC ACID, Cyanuric acid amidohydrolase, MAGNESIUM ION, ...
Authors:Cho, S, Shi, K, Aihara, H.
Deposit date:2013-11-23
Release date:2014-09-10
Method:X-RAY DIFFRACTION (2.702 Å)
Cite:Cyanuric acid hydrolase from Azorhizobium caulinodans ORS 571: crystal structure and insights into a new class of Ser-Lys dyad proteins.
Plos One, 9, 2014
7RXS
DownloadVisualize
BU of 7rxs by Molmil
Crystal of BRD4(D1) with 2-[(3S)-3-{5-[2-(3,5-dimethylphenoxy)pyrimidin-4-yl]-4-(4-iodophenyl)-1H-imidazol-1-yl}pyrrolidin-1-yl]ethan-1-amine
Descriptor: 1,2-ETHANEDIOL, 2-[(3S)-3-{5-[2-(3,5-dimethylphenoxy)pyrimidin-4-yl]-4-(4-iodophenyl)-1H-imidazol-1-yl}pyrrolidin-1-yl]ethan-1-amine, Bromodomain-containing protein 4
Authors:Cui, H, Johnson, J.A, Shi, K, Aihara, H, Pomerantz, W.C.K.
Deposit date:2021-08-23
Release date:2022-01-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.43 Å)
Cite:A Structure-based Design Approach for Generating High Affinity BRD4 D1-Selective Chemical Probes.
J.Med.Chem., 65, 2022
7RXT
DownloadVisualize
BU of 7rxt by Molmil
Crystal of BRD4(D1) with 2-[(3R)-3-{5-[2-(3,5-dimethylphenoxy)pyrimidin-4-yl]-4-(4-iodophenyl)-1H-imidazol-1-yl}pyrrolidin-1-yl]ethan-1-amine
Descriptor: 2-[(3R)-3-{5-[2-(3,5-dimethylphenoxy)pyrimidin-4-yl]-4-(4-iodophenyl)-1H-imidazol-1-yl}pyrrolidin-1-yl]ethan-1-amine, Bromodomain-containing protein 4
Authors:Cui, H, Johnson, J.A, Shi, K, Aihara, H, Pomerantz, W.C.K.
Deposit date:2021-08-23
Release date:2022-01-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:A Structure-based Design Approach for Generating High Affinity BRD4 D1-Selective Chemical Probes.
J.Med.Chem., 65, 2022
7RXR
DownloadVisualize
BU of 7rxr by Molmil
Crystal Structure of BRD4(D1) with 4-[4-(4-bromophenyl)-1-(piperidin-4-yl)-1H-imidazol-5-yl]-N-(3,5-dimethylphenyl)pyrimidin-2-amine
Descriptor: 1,2-ETHANEDIOL, 4-[4-(4-bromophenyl)-1-(piperidin-4-yl)-1H-imidazol-5-yl]-N-(3,5-dimethylphenyl)pyrimidin-2-amine, Bromodomain-containing protein 4
Authors:Cui, H, Johnson, J.A, Shi, K, Aihara, H, Pomerantz, W.C.K.
Deposit date:2021-08-23
Release date:2022-01-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.41 Å)
Cite:A Structure-based Design Approach for Generating High Affinity BRD4 D1-Selective Chemical Probes.
J.Med.Chem., 65, 2022
6O44
DownloadVisualize
BU of 6o44 by Molmil
Insight into subtilisin E-S7 cleavage pattern based on crystal structure and hydrolysates peptide analysis
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, Nattokinase, ...
Authors:Tang, H, Shi, K, Aihara, H.
Deposit date:2019-02-28
Release date:2019-04-10
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Insight into subtilisin E-S7 cleavage pattern based on crystal structure and hydrolysates peptide analysis.
Biochem. Biophys. Res. Commun., 512, 2019
7R9C
DownloadVisualize
BU of 7r9c by Molmil
Cocrystal of BRD4(D1) with N,N-dimethyl-2-[(3R)-3-(5-{2-[2-methyl-5-(propan-2-yl)phenoxy]pyrimidin-4-yl}-4-[4-(trifluoromethyl)phenyl]-1H-imidazol-1-yl)pyrrolidin-1-yl]ethan-1-amine
Descriptor: 1,2-ETHANEDIOL, Bromodomain-containing protein 4, CHLORIDE ION, ...
Authors:Cui, H, Shi, K, Aihara, H, Pomerantz, W.C.K.
Deposit date:2021-06-29
Release date:2022-01-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:A Structure-based Design Approach for Generating High Affinity BRD4 D1-Selective Chemical Probes.
J.Med.Chem., 65, 2022
7RWN
DownloadVisualize
BU of 7rwn by Molmil
Crystal Structure of BPTF bromodomain in complex with 4-chloro-5-{4-[(dimethylamino)methyl]anilino}-2-methylpyridazin-3(2H)-one
Descriptor: 1,2-ETHANEDIOL, 4-chloro-5-{4-[(dimethylamino)methyl]anilino}-2-methylpyridazin-3(2H)-one, Nucleosome-remodeling factor subunit BPTF
Authors:Zahid, H, Buchholz, C, Johnson, J.A, Shi, K, Aihara, H, Pomerantz, W.C.K.
Deposit date:2021-08-20
Release date:2022-08-24
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.39 Å)
Cite:New Design Rules for Developing Potent Cell-Active Inhibitors of the Nucleosome Remodeling Factor (NURF) via BPTF Bromodomain Inhibition.
J.Med.Chem., 64, 2021
7RWP
DownloadVisualize
BU of 7rwp by Molmil
Crystal Structure of BPTF bromodomain in complex with 5-[4-(aminomethyl)anilino]-4-chloro-2-methylpyridazin-3(2H)-one
Descriptor: 5-[4-(aminomethyl)anilino]-4-chloro-2-methylpyridazin-3(2H)-one, CALCIUM ION, Nucleosome-remodeling factor subunit BPTF
Authors:Zahid, H, Buchholz, C, Johnson, J.A, Shi, K, Aihara, H, Pomerantz, W.C.K.
Deposit date:2021-08-20
Release date:2022-08-24
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:New Design Rules for Developing Potent Cell-Active Inhibitors of the Nucleosome Remodeling Factor (NURF) via BPTF Bromodomain Inhibition.
J.Med.Chem., 64, 2021
7RWQ
DownloadVisualize
BU of 7rwq by Molmil
Crystal Structure of BPTF bromodomain in complex with 4-chloro-2-methyl-5-[(1,2,3,4-tetrahydroisoquinolin-6-yl)amino]pyridazin-3(2H)-one
Descriptor: 4-chloro-2-methyl-5-[(1,2,3,4-tetrahydroisoquinolin-6-yl)amino]pyridazin-3(2H)-one, CALCIUM ION, Nucleosome-remodeling factor subunit BPTF
Authors:Zahid, H, Buchholz, C, Johnson, J.A, Shi, K, Aihara, H, Pomerantz, W.C.K.
Deposit date:2021-08-20
Release date:2022-08-24
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:New Design Rules for Developing Potent Cell-Active Inhibitors of the Nucleosome Remodeling Factor (NURF) via BPTF Bromodomain Inhibition.
J.Med.Chem., 64, 2021
7RWO
DownloadVisualize
BU of 7rwo by Molmil
Crystal Structure of BPTF bromodomain in complex with 4-chloro-2-methyl-5-[(1,2,3,4-tetrahydroisoquinolin-7-yl)amino]pyridazin-3(2H)-one
Descriptor: 1,2-ETHANEDIOL, 4-chloro-2-methyl-5-[(1,2,3,4-tetrahydroisoquinolin-7-yl)amino]pyridazin-3(2H)-one, Nucleosome-remodeling factor subunit BPTF
Authors:Zahid, H, Buchholz, C, Johnson, J.A, Shi, K, Aihara, H, Pomerantz, W.C.K.
Deposit date:2021-08-20
Release date:2022-08-24
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:New Design Rules for Developing Potent Cell-Active Inhibitors of the Nucleosome Remodeling Factor (NURF) via BPTF Bromodomain Inhibition.
J.Med.Chem., 64, 2021

225158

PDB entries from 2024-09-18

PDB statisticsPDBj update infoContact PDBjnumon