Author results

3M7T
  • Download 3m7t
  • View 3m7t
Molmil generated image of 3m7t
CRYSTAL STRUCTURE OF ALPHA-LYTIC PROTEASE SB2+3 E8A/R105S MUTANT
Descriptor:Alpha-lytic protease, GLYCEROL, SULFATE ION
Authors:Agard, D.A., Erciyas Bailey, F.P., Waddling, C.A.
Deposit date:2010-03-17
Release date:2011-02-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Quantifying protein unfolding cooperativity with acid sensitive probes: Interdomain salt bridge contributions to unfolding cooperativity are combined efficiently in alpha-Lytic Protease
To be Published
3M7U
  • Download 3m7u
  • View 3m7u
Molmil generated image of 3m7u
CRYSTAL STRUCTURE OF ALPHA-LYTIC PROTEASE SB1+2 R64A/E182Q MUTANT
Descriptor:Alpha-lytic protease, SELF-PROTEOLYSIS PRODUCT (RESIDUES 184-187), SULFATE ION
Authors:Agard, D.A., Erciyas Bailey, F.P., Waddling, C.A.
Deposit date:2010-03-17
Release date:2011-02-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.05 Å)
Cite:Quantifying protein unfolding cooperativity with acid sensitive probes: Interdomain salt bridge contributions to unfolding cooperativity are combined efficiently in alpha-Lytic Protease
To be Published
3J4T
  • Download 3j4t
  • View 3j4t
Molmil generated image of 3j4t
HELICAL MODEL OF TUBZ-BT TWO-STRANDED FILAMENT
Descriptor:FtsZ/tubulin-related protein
Authors:Agard, D.A., Montabana, E.A.
Deposit date:2013-10-04
Release date:2014-02-19
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (10.8 Å)
Cite:Bacterial tubulin TubZ-Bt transitions between a two-stranded intermediate and a four-stranded filament upon GTP hydrolysis.
Proc.Natl.Acad.Sci.USA, 111, 2014
3R4V
  • Download 3r4v
  • View 3r4v
Molmil generated image of 3r4v
STRUCTURE OF THE PHAGE TUBULIN PHUZ-GDP
Descriptor:Putative uncharacterized protein, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
Authors:Agard, D.A., Pogliano, J., Kraemer, J.A., Erb, M.L., Waddling, C.A., Montabana, E.A., Wang, H., Nguyen, K., Pham, S.
Deposit date:2011-03-17
Release date:2012-07-04
Last modified:2013-01-23
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:A phage tubulin assembles dynamic filaments by an atypical mechanism to center viral DNA within the host cell.
Cell(Cambridge,Mass.), 149, 2012
3RB8
  • Download 3rb8
  • View 3rb8
Molmil generated image of 3rb8
STRUCTURE OF THE PHAGE TUBULIN PHUZ(SEMET)-GDP
Descriptor:Putative uncharacterized protein, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
Authors:Agard, D.A., Pogliano, J., Kraemer, J.A., Erb, M.L., Waddling, C.A., Montabana, E.A., Wang, H., Nguyen, K., Pham, S.
Deposit date:2011-03-28
Release date:2012-07-04
Last modified:2013-01-23
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A phage tubulin assembles dynamic filaments by an atypical mechanism to center viral DNA within the host cell.
Cell(Cambridge,Mass.), 149, 2012
2LPR
  • Download 2lpr
  • View 2lpr
Molmil generated image of 2lpr
STRUCTURAL BASIS FOR BROAD SPECIFICITY IN ALPHA-LYTIC PROTEASE MUTANTS
Descriptor:ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-VALINE BORONIC ACID INHIBITOR, SULFATE ION
Authors:Bone, R., Agard, D.A.
Deposit date:1991-08-05
Release date:1993-01-15
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural basis for broad specificity in alpha-lytic protease mutants.
Biochemistry, 30, 1991
3LPR
  • Download 3lpr
  • View 3lpr
Molmil generated image of 3lpr
STRUCTURAL BASIS FOR BROAD SPECIFICITY IN ALPHA-LYTIC PROTEASE MUTANTS
Descriptor:ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-NORLEUCINE BORONIC ACID INHIBITOR, SULFATE ION
Authors:Bone, R., Agard, D.A.
Deposit date:1991-08-05
Release date:1993-01-15
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural basis for broad specificity in alpha-lytic protease mutants.
Biochemistry, 30, 1991
5LPR
  • Download 5lpr
  • View 5lpr
Molmil generated image of 5lpr
STRUCTURAL BASIS FOR BROAD SPECIFICITY IN ALPHA-LYTIC PROTEASE MUTANTS
Descriptor:ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-ALANINE BORONIC ACID INHIBITOR, SULFATE ION
Authors:Fujishige, A., Bone, R., Agard, D.A.
Deposit date:1991-08-05
Release date:1993-01-15
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Structural basis for broad specificity in alpha-lytic protease mutants.
Biochemistry, 30, 1991
6LPR
  • Download 6lpr
  • View 6lpr
Molmil generated image of 6lpr
STRUCTURAL BASIS FOR BROAD SPECIFICITY IN ALPHA-LYTIC PROTEASE MUTANTS
Descriptor:ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-NORLEUCINE BORONIC ACID INHIBITOR, SULFATE ION
Authors:Bone, R., Agard, D.A.
Deposit date:1991-08-05
Release date:1993-01-15
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis for broad specificity in alpha-lytic protease mutants.
Biochemistry, 30, 1991
7LPR
  • Download 7lpr
  • View 7lpr
Molmil generated image of 7lpr
STRUCTURAL BASIS FOR BROAD SPECIFICITY IN ALPHA-LYTIC PROTEASE MUTANTS
Descriptor:ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-LEUCINE BORONIC ACID INHIBITOR, SULFATE ION
Authors:Fujishige, A., Bone, R., Agard, D.A.
Deposit date:1991-08-05
Release date:1993-01-15
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural basis for broad specificity in alpha-lytic protease mutants.
Biochemistry, 30, 1991
8LPR
  • Download 8lpr
  • View 8lpr
Molmil generated image of 8lpr
STRUCTURAL BASIS FOR BROAD SPECIFICITY IN ALPHA-LYTIC PROTEASE MUTANTS
Descriptor:ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-PHENYLALANINE BORONIC ACID INHIBITOR, SULFATE ION
Authors:Fujishige, A., Bone, R., Agard, D.A.
Deposit date:1991-08-05
Release date:1993-01-15
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural basis for broad specificity in alpha-lytic protease mutants.
Biochemistry, 30, 1991
9LPR
  • Download 9lpr
  • View 9lpr
Molmil generated image of 9lpr
STRUCTURAL BASIS FOR BROAD SPECIFICITY IN ALPHA-LYTIC PROTEASE MUTANTS
Descriptor:ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-LEUCINE BORONIC ACID INHIBITOR, SULFATE ION
Authors:Bone, R., Agard, D.A.
Deposit date:1991-08-05
Release date:1993-01-15
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis for broad specificity in alpha-lytic protease mutants.
Biochemistry, 30, 1991
1BOQ
  • Download 1boq
  • View 1boq
Molmil generated image of 1boq
PRO REGION C-TERMINUS: PROTEASE ACTIVE SITE INTERACTIONS ARE CRITICAL IN CATALYZING THE FOLDING OF ALPHA-LYTIC PROTEASE
Descriptor:PROTEIN (ALPHA-LYTIC PROTEASE), SULFATE ION
Authors:Peters, R.J., Shiau, A.K., Sohl, J.L., Anderson, D.E., Tang, G., Silen, J.L., Agard, D.A.
Deposit date:1998-08-05
Release date:1998-08-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Pro region C-terminus:protease active site interactions are critical in catalyzing the folding of alpha-lytic protease.
Biochemistry, 37, 1998
1GBA
  • Download 1gba
  • View 1gba
Molmil generated image of 1gba
ALPHA-LYTIC PROTEASE WITH MET 190 REPLACED BY ALA AND GLY 216 REPLACED BY ALA
Descriptor:ALPHA-LYTIC PROTEASE, SULFATE ION
Authors:Mace, J.E., Agard, D.A.
Deposit date:1995-09-06
Release date:1996-01-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Kinetic and structural characterization of mutations of glycine 216 in alpha-lytic protease: a new target for engineering substrate specificity.
J.Mol.Biol., 254, 1995
1GBB
  • Download 1gbb
  • View 1gbb
Molmil generated image of 1gbb
ALPHA-LYTIC PROTEASE WITH MET 190 REPLACED BY ALA AND GLY 216 REPLACED BY ALA COMPLEX WITH METHOXYSUCCINYL-ALA-ALA-PRO-ALANINE BORONIC ACID
Descriptor:ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-ALANINE BORONIC ACID INHIBITOR, SULFATE ION
Authors:Mace, J.E., Agard, D.A.
Deposit date:1995-09-06
Release date:1996-01-29
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Kinetic and structural characterization of mutations of glycine 216 in alpha-lytic protease: a new target for engineering substrate specificity.
J.Mol.Biol., 254, 1995
1GBC
  • Download 1gbc
  • View 1gbc
Molmil generated image of 1gbc
ALPHA-LYTIC PROTEASE WITH MET 190 REPLACED BY ALA AND GLY 216 REPLACED BY ALA COMPLEX WITH METHOXYSUCCINYL-ALA-ALA-PRO-LEUCINE BORONIC ACID
Descriptor:ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-LEUCINE BORONIC ACID INHIBITOR, SULFATE ION
Authors:Mace, J.E., Agard, D.A.
Deposit date:1995-09-06
Release date:1996-01-29
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Kinetic and structural characterization of mutations of glycine 216 in alpha-lytic protease: a new target for engineering substrate specificity.
J.Mol.Biol., 254, 1995
1GBD
  • Download 1gbd
  • View 1gbd
Molmil generated image of 1gbd
ALPHA-LYTIC PROTEASE WITH MET 190 REPLACED BY ALA AND GLY 216 REPLACED BY ALA COMPLEX WITH METHOXYSUCCINYL-ALA-ALA-PRO-PHENYLALANINE BORONIC ACID
Descriptor:ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-PHENYLALANINE BORONIC ACID INHIBITOR, SULFATE ION
Authors:Mace, J.E., Agard, D.A.
Deposit date:1995-09-06
Release date:1996-01-29
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Kinetic and structural characterization of mutations of glycine 216 in alpha-lytic protease: a new target for engineering substrate specificity.
J.Mol.Biol., 254, 1995
1GBE
  • Download 1gbe
  • View 1gbe
Molmil generated image of 1gbe
ALPHA-LYTIC PROTEASE WITH MET 190 REPLACED BY ALA AND GLY 216 REPLACED BY LEU
Descriptor:ALPHA-LYTIC PROTEASE, SULFATE ION
Authors:Mace, J.E., Agard, D.A.
Deposit date:1995-09-06
Release date:1996-01-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Kinetic and structural characterization of mutations of glycine 216 in alpha-lytic protease: a new target for engineering substrate specificity.
J.Mol.Biol., 254, 1995
1GBF
  • Download 1gbf
  • View 1gbf
Molmil generated image of 1gbf
ALPHA-LYTIC PROTEASE WITH MET 190 REPLACED BY ALA AND GLY 216 REPLACED BY LEU COMPLEX WITH METHOXYSUCCINYL-ALA-ALA-PRO-ALANINE BORONIC ACID
Descriptor:ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-ALANINE BORONIC ACID INHIBITOR, SULFATE ION
Authors:Mace, J.E., Agard, D.A.
Deposit date:1995-09-06
Release date:1996-01-29
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Kinetic and structural characterization of mutations of glycine 216 in alpha-lytic protease: a new target for engineering substrate specificity.
J.Mol.Biol., 254, 1995
1GBH
  • Download 1gbh
  • View 1gbh
Molmil generated image of 1gbh
ALPHA-LYTIC PROTEASE WITH MET 190 REPLACED BY ALA AND GLY 216 REPLACED BY LEU COMPLEX WITH METHOXYSUCCINYL-ALA-ALA-PRO-LEUCINE BORONIC ACID
Descriptor:ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-LEUCINE BORONIC ACID INHIBITOR, SULFATE ION
Authors:Mace, J.E., Agard, D.A.
Deposit date:1995-09-06
Release date:1996-01-29
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Kinetic and structural characterization of mutations of glycine 216 in alpha-lytic protease: a new target for engineering substrate specificity.
J.Mol.Biol., 254, 1995
1GBI
  • Download 1gbi
  • View 1gbi
Molmil generated image of 1gbi
ALPHA-LYTIC PROTEASE WITH MET 190 REPLACED BY ALA AND GLY 216 REPLACED BY LEU COMPLEX WITH METHOXYSUCCINYL-ALA-ALA-PRO-PHENYLALANINE BORONIC ACID
Descriptor:ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-PHENYLALANINE BORONIC ACID INHIBITOR, SULFATE ION
Authors:Mace, J.E., Agard, D.A.
Deposit date:1995-09-06
Release date:1996-01-29
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Kinetic and structural characterization of mutations of glycine 216 in alpha-lytic protease: a new target for engineering substrate specificity.
J.Mol.Biol., 254, 1995
1GBJ
  • Download 1gbj
  • View 1gbj
Molmil generated image of 1gbj
ALPHA-LYTIC PROTEASE WITH MET 190 REPLACED BY ALA
Descriptor:ALPHA-LYTIC PROTEASE, SULFATE ION
Authors:Mace, J.E., Agard, D.A.
Deposit date:1995-09-06
Release date:1996-01-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Kinetic and structural characterization of mutations of glycine 216 in alpha-lytic protease: a new target for engineering substrate specificity.
J.Mol.Biol., 254, 1995
1GBK
  • Download 1gbk
  • View 1gbk
Molmil generated image of 1gbk
ALPHA-LYTIC PROTEASE WITH MET 190 REPLACED BY ALA COMPLEX WITH METHOXYSUCCINYL-ALA-ALA-PRO-ALANINE BORONIC ACID
Descriptor:ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-ALANINE BORONIC ACID INHIBITOR, SULFATE ION
Authors:Mace, J.E., Agard, D.A.
Deposit date:1995-09-06
Release date:1996-01-29
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Kinetic and structural characterization of mutations of glycine 216 in alpha-lytic protease: a new target for engineering substrate specificity.
J.Mol.Biol., 254, 1995
1GBL
  • Download 1gbl
  • View 1gbl
Molmil generated image of 1gbl
ALPHA-LYTIC PROTEASE WITH MET 190 REPLACED BY ALA COMPLEX WITH METHOXYSUCCINYL-ALA-ALA-PRO-LEUCINE BORONIC ACID
Descriptor:ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-LEUCINE BORONIC ACID INHIBITOR, SULFATE ION
Authors:Mace, J.E., Agard, D.A.
Deposit date:1995-09-06
Release date:1996-01-29
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Kinetic and structural characterization of mutations of glycine 216 in alpha-lytic protease: a new target for engineering substrate specificity.
J.Mol.Biol., 254, 1995
1GBM
  • Download 1gbm
  • View 1gbm
Molmil generated image of 1gbm
ALPHA-LYTIC PROTEASE WITH MET 190 REPLACED BY ALA COMPLEX WITH METHOXYSUCCINYL-ALA-ALA-PRO-PHENYLALANINE BORONIC ACID
Descriptor:ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-PHENYLALANINE BORONIC ACID INHIBITOR, SULFATE ION
Authors:Mace, J.E., Agard, D.A.
Deposit date:1995-09-06
Release date:1996-01-29
Last modified:2014-09-17
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Kinetic and structural characterization of mutations of glycine 216 in alpha-lytic protease: a new target for engineering substrate specificity.
J.Mol.Biol., 254, 1995