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4L43
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CRYSTAL STRUCTURES OF HUMAN P70S6K1-T389A (FORM I)
分子名称:RPS6KB1 protein, 2-{[4-(5-ethylpyrimidin-4-yl)piperazin-1-yl]methyl}-5-(trifluoromethyl)-1H-benzimidazole
著者Wang, J., Zhong, C., Ding, J.
登録日2013-06-07
公開日2013-07-24
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structures of S6K1 provide insights into the regulation mechanism of S6K1 by the hydrophobic motif
Biochem.J., 454, 2013
4L44
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CRYSTAL STRUCTURES OF HUMAN P70S6K1-T389A (FORM II)
分子名称:RPS6KB1 protein, SULFATE ION, 2-{[4-(5-ethylpyrimidin-4-yl)piperazin-1-yl]methyl}-5-(trifluoromethyl)-1H-benzimidazole, ...
著者Wang, J., Zhong, C., Ding, J.
登録日2013-06-07
公開日2013-07-24
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structures of S6K1 provide insights into the regulation mechanism of S6K1 by the hydrophobic motif
Biochem.J., 454, 2013
4L45
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CRYSTAL STRUCTURES OF HUMAN P70S6K1-T389E
分子名称:RPS6KB1 protein, 2-{[4-(5-ethylpyrimidin-4-yl)piperazin-1-yl]methyl}-5-(trifluoromethyl)-1H-benzimidazole
著者Wang, J., Zhong, C., Ding, J.
登録日2013-06-07
公開日2013-07-24
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structures of S6K1 provide insights into the regulation mechanism of S6K1 by the hydrophobic motif
Biochem.J., 454, 2013
4L46
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CRYSTAL STRUCTURES OF HUMAN P70S6K1-WT
分子名称:RPS6KB1 protein, 2-{[4-(5-ethylpyrimidin-4-yl)piperazin-1-yl]methyl}-5-(trifluoromethyl)-1H-benzimidazole, SULFATE ION, ...
著者Wang, J., Zhong, C., Ding, J.
登録日2013-06-07
公開日2013-07-24
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (3.01 Å)
主引用文献Crystal structures of S6K1 provide insights into the regulation mechanism of S6K1 by the hydrophobic motif
Biochem.J., 454, 2013
4LAK
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CRYSTAL STRUCTURE OF CORDYCEPS MILITARIS IDCASE D323N MUTANT IN APO FORM
分子名称:Uracil-5-carboxylate decarboxylase, ZINC ION
著者Xu, S., Li, W., Zhu, J., Wang, R., Li, Z., Xu, G.L., Ding, J.
登録日2013-06-20
公開日2013-10-02
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献Crystal structures of isoorotate decarboxylases reveal a novel catalytic mechanism of 5-carboxyl-uracil decarboxylation and shed light on the search for DNA decarboxylase.
Cell Res., 23, 2013
4LAL
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CRYSTAL STRUCTURE OF CORDYCEPS MILITARIS IDCASE D323A MUTANT IN COMPLEX WITH 5-CARBOXYL-URACIL
分子名称:Uracil-5-carboxylate decarboxylase, ZINC ION, 2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid, ...
著者Xu, S., Li, W., Zhu, J., Ding, J.
登録日2013-06-20
公開日2013-10-02
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structures of isoorotate decarboxylases reveal a novel catalytic mechanism of 5-carboxyl-uracil decarboxylation and shed light on the search for DNA decarboxylase.
Cell Res., 23, 2013
4LAM
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CRYSTAL STRUCTURE OF CORDYCEPS MILITARIS IDCASE D323N MUTANT IN COMPLEX WITH 5-CARBOXYL-URACIL
分子名称:Uracil-5-carboxylate decarboxylase, ZINC ION, 2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid, ...
著者Xu, S., Li, W., Zhu, J., Ding, J.
登録日2013-06-20
公開日2013-10-02
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structures of isoorotate decarboxylases reveal a novel catalytic mechanism of 5-carboxyl-uracil decarboxylation and shed light on the search for DNA decarboxylase.
Cell Res., 23, 2013
4LAN
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CRYSTAL STRUCTURE OF CORDYCEPS MILITARIS IDCASE H195A MUTANT
分子名称:Uracil-5-carboxylate decarboxylase, ZINC ION
著者Xu, S., Li, W., Zhu, J., Ding, J.
登録日2013-06-20
公開日2013-10-02
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Crystal structures of isoorotate decarboxylases reveal a novel catalytic mechanism of 5-carboxyl-uracil decarboxylation and shed light on the search for DNA decarboxylase.
Cell Res., 23, 2013
4LAO
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CRYSTAL STRUCTURE OF CORDYCEPS MILITARIS IDCASE H195A MUTANT (ZN)
分子名称:Cordyceps militaris IDCase, ZINC ION, DI(HYDROXYETHYL)ETHER
著者Xu, S., Li, W., Zhu, J., Ding, J.
登録日2013-06-20
公開日2013-10-02
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structures of isoorotate decarboxylases reveal a novel catalytic mechanism of 5-carboxyl-uracil decarboxylation and shed light on the search for DNA decarboxylase.
Cell Res., 23, 2013
4N3X
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CRYSTAL STRUCTURE OF RABEX-5 CC DOMAIN
分子名称:Rab5 GDP/GTP exchange factor
著者Zhang, Z., Zhang, T., Ding, J.
登録日2013-10-08
公開日2014-07-23
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Molecular mechanism for Rabex-5 GEF activation by Rabaptin-5
Elife, 3, 2014
4N3Y
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CRYSTAL STRUCTURE OF RABEX-5CC AND RABAPTIN-5C21 COMPLEX
分子名称:Rab5 GDP/GTP exchange factor, Rab GTPase-binding effector protein 1
著者Zhang, Z., Zhang, T., Ding, J.
登録日2013-10-08
公開日2014-07-23
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Molecular mechanism for Rabex-5 GEF activation by Rabaptin-5
Elife, 3, 2014
4N3Z
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CRYSTAL STRUCTURE OF RABEX-5DELTA AND RABAPTIN-5C21 COMPLEX
分子名称:Rab5 GDP/GTP exchange factor, Rab GTPase-binding effector protein 1, PHOSPHATE ION
著者Zhang, Z., Zhang, T., Ding, J.
登録日2013-10-08
公開日2014-07-23
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Molecular mechanism for Rabex-5 GEF activation by Rabaptin-5
Elife, 3, 2014
4O0S
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CRYSTAL STRUCTURES OF HUMAN KINASE AURORA A
分子名称:Aurora kinase A, ADENOSINE
著者Wang, J., Zhang, L., Ding, J.
登録日2013-12-14
公開日2014-12-17
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Functional Role of Conserved HxD-histidine in the Catalytic Core of Protein Kinases
To be Published
4O0U
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CRYSTAL STRUCTURES OF HUMAN KINASE AURORA A
分子名称:Aurora kinase A, ADENOSINE
著者Wang, J., Zhang, L., Ding, J.
登録日2013-12-14
公開日2014-12-17
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Functional Role of Conserved HxD-histidine in the Catalytic Core of Protein Kinases
To be Published
4O0W
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CRYSTAL STRUCTURES OF HUMAN KINASE AURORA A
分子名称:Aurora kinase A, ADENOSINE
著者Wang, J., Zhang, L., Ding, J.
登録日2013-12-14
公開日2014-12-17
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Functional Role of Conserved HxD-histidine in the Catalytic Core of Protein Kinase
To be Published
4Q9U
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CRYSTAL STRUCTURE OF THE RAB5, RABEX-5DELTA AND RABAPTIN-5C21 COMPLEX
分子名称:Rab5 GDP/GTP exchange factor, Ras-related protein Rab-5A, Rab GTPase-binding effector protein 1
著者Zhang, Z., Zhang, T., Ding, J.
登録日2014-05-01
公開日2014-07-23
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (4.618 Å)
主引用文献Molecular mechanism for Rabex-5 GEF activation by Rabaptin-5
Elife, 3, 2014
4QTJ
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COMPLEX OF WOPR DOMAIN OF WOR1 IN CANDIDA ALBICANS WITH THE 13BP DSDNA
分子名称:White-opaque regulator 1, DNA (5'-D(*AP*AP*AP*AP*GP*TP*TP*TP*AP*AP*CP*TP*T)-3'), DNA (5'-D(*AP*AP*GP*TP*TP*AP*AP*AP*CP*TP*TP*TP*T)-3')
著者Zhang, S., Zhang, T., Ding, J.
登録日2014-07-08
公開日2014-08-13
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of the WOPR-DNA complex and implications for Wor1 function in white-opaque switching of Candida albicans.
Cell Res., 2014
4QTK
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COMPLEX OF WOPR DOMAIN OF WOR1 IN CANDIDA ALBICANS WITH THE 17BP DSDNA
分子名称:White-opaque regulator 1, DNA (5'-D(*TP*CP*AP*AP*AP*AP*AP*AP*GP*TP*TP*TP*AP*AP*CP*TP*T)-3'), DNA (5'-D(*AP*AP*GP*TP*TP*AP*AP*AP*CP*TP*TP*TP*TP*TP*TP*GP*A)-3')
著者Zhang, S., Zhang, T., Ding, J.
登録日2014-07-08
公開日2014-08-13
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (2.99 Å)
主引用文献Crystal structure of the WOPR-DNA complex and implications for Wor1 function in white-opaque switching of Candida albicans.
Cell Res., 2014
4QXA
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CRYSTAL STRUCTURE OF THE RAB9A-RUTBC2 RBD COMPLEX
分子名称:Ras-related protein Rab-9A, Small G protein signaling modulator 1, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Zhang, Z., Wang, S., Ding, J.
登録日2014-07-19
公開日2014-09-10
最終更新日2019-12-25
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of the Rab9A-RUTBC2 RBD complex reveals the molecular basis for the binding specificity of Rab9A with RUTBC2.
Structure, 22, 2014
5B7J
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STRUCTURE MODEL OF SAP1-DNA COMPLEX
分子名称:Switch-activating protein 1, DNA (5'-D(*CP*AP*AP*AP*AP*CP*AP*AP*TP*AP*TP*T)-3'), DNA (5'-D(*AP*AP*TP*AP*TP*TP*GP*TP*TP*TP*TP*G)-3')
著者Jin, C., Hu, Y., Ding, J., Zhang, Y.
登録日2016-06-07
公開日2017-02-22
最終更新日2017-05-24
実験手法SOLUTION NMR
主引用文献Sap1 is a replication-initiation factor essential for the assembly of pre-replicative complex in the fission yeast Schizosaccharomyces pombe
J. Biol. Chem., 292, 2017
5EUD
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S1P LYASE BACTERIAL SURROGATE BOUND TO N-(1-(4-(3-HYDROXYPROP-1-YN-1-YL)PHENYL)-2-((4-METHOXY-2,5-DIMETHYLBENZYL)AMINO)ETHYL)-5-METHYLISOXAZOLE-3-CARBOXAMIDE
分子名称:Putative sphingosine-1-phosphate lyase, PHOSPHATE ION, ~{N}-[(1~{S})-2-[(4-methoxy-2,5-dimethyl-phenyl)methylamino]-1-[4-(3-oxidanylprop-1-ynyl)phenyl]ethyl]-5-methyl-1,2-oxazole-3-carboxamide
著者Argiriadi, M.A., Banach, D., Radziejewska, E., Marchie, S., DiMauro, J., Dinges, J., Dominguez, E., Hutchins, C., Judge, R.A., Queeney, K., Wallace, G., Harris, C.M.
登録日2015-11-18
公開日2016-03-16
最終更新日2016-07-20
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献Creation of a S1P Lyase bacterial surrogate for structure-based drug design.
Bioorg.Med.Chem.Lett., 26, 2016
5EUE
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S1P LYASE BACTERIAL SURROGATE BOUND TO N-(2-((4-METHOXY-2,5-DIMETHYLBENZYL)AMINO)-1-PHENYLETHYL)-5-METHYLISOXAZOLE-3-CARBOXAMIDE
分子名称:Putative sphingosine-1-phosphate lyase, ~{N}-[(1~{S})-2-[(4-methoxy-2,5-dimethyl-phenyl)methylamino]-1-phenyl-ethyl]-5-methyl-1,2-oxazole-3-carboxamide, PHOSPHATE ION
著者Argiriadi, M.A., Banach, D., Radziejewska, E., Marchie, S., DiMauro, J., Dinges, J., Dominguez, E., Hutchins, C., Judge, R.A., Queeney, K., Wallace, G., Harris, C.M.
登録日2015-11-18
公開日2016-03-16
最終更新日2016-07-20
実験手法X-RAY DIFFRACTION (2.83 Å)
主引用文献Creation of a S1P Lyase bacterial surrogate for structure-based drug design.
Bioorg.Med.Chem.Lett., 26, 2016
5GJS
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CRYSTAL STRUCTURE OF H1 HEMAGGLUTININ FROM A/CALIFORNIA/04/2009 IN COMPLEX WITH A NEUTRALIZING ANTIBODY 3E1
分子名称:Hemagglutinin, light chain of human neutralizing antibody 3E1, heavy chain of human neutralizing antibody 3E1, ...
著者Wang, W., Zhang, T., Ding, J.
登録日2016-07-01
公開日2016-12-07
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Human antibody 3E1 targets the HA stem region of H1N1 and H5N6 influenza A viruses
Nat Commun, 7, 2016
5GJT
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CRYSTAL STRUCTURE OF H1 HEMAGGLUTININ FROM A/WASHINGTON/05/2011 IN COMPLEX WITH A NEUTRALIZING ANTIBODY 3E1
分子名称:Hemagglutinin, light chain of human neutralizing antibody 3E1, heavy chain of human neutralizing antibody 3E1, ...
著者Wang, W., Zhang, T., Ding, J.
登録日2016-07-01
公開日2016-12-07
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Human antibody 3E1 targets the HA stem region of H1N1 and H5N6 influenza A viruses
Nat Commun, 7, 2016
5GK9
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CRYSTAL STRUCTURE OF HUMAN HBO1 IN COMPLEX WITH BRPF2
分子名称:Histone acetyltransferase KAT7, BRD1 protein, ZINC ION, ...
著者Tao, Y., Zhu, J., Xu, S., Ding, J.
登録日2016-07-04
公開日2017-03-29
最終更新日2017-12-06
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural and mechanistic insights into regulation of HBO1 histone acetyltransferase activity by BRPF2.
Nucleic Acids Res., 45, 2017
167327
件を2020-08-05に公開中