Author results

5WY2
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HUMAN SNX5 PX DOMAIN IN COMPLEX WITH CHLAMYDIA INCE C TERMINUS
Descriptor:Sorting nexin-5, IncE
Authors:Sun, Q., Yong, X., Jia, D.
Deposit date:2017-01-10
Release date:2017-11-22
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and functional insights into sorting nexin 5/6 interaction with bacterial effector IncE
Signal Transduct Target Ther, 2, 2017
1AGK
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THE SOLUTION NMR STRUCTURE OF AN (R)-A-(N6-ADENYL)-STYRENE OXIDE-RAS61 OLIGODEOXYNUCLEOTIDE MODIFIED AT THE SECOND POSITION OF THE CODON 61 REGION, MINIMIZED AVERAGE STRUCTURE
Descriptor:DNA (5'-D(*CP*GP*GP*AP*CP*RP*AP*GP*AP*AP*G)-3'), DNA (5'-D(*CP*TP*TP*CP*TP*TP*GP*TP*CP*CP*G)-3')
Authors:Feng, B., Stone, M.P.
Deposit date:1997-03-25
Release date:1997-08-20
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Major groove (R)-alpha-(N6-adenyl)styrene oxide adducts in an oligodeoxynucleotide containing the human N-ras codon 61 sequence: conformations of the R(61,2) and R(61,3) sequence isomers from 1H NMR.
Biochemistry, 34, 1995
1AGO
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THE SOLUTION NMR STRUCTURE OF AN (S)-A-(N6-ADENYL)-STYRENE OXIDE-RAS61 OLIGODEOXYNUCLEOTIDE MODIFIED AT THE THIRD POSITION OF THE CODON 61 REGION, MINIMIZED AVERAGE STRUCTURE
Descriptor:DNA (5'-D(*CP*GP*GP*AP*CP*AP*YP*GP*AP*AP*G)-3'), DNA (5'-D(*CP*TP*TP*CP*TP*TP*GP*TP*CP*CP*G)-3')
Authors:Feng, B., Stone, M.P.
Deposit date:1997-03-25
Release date:1997-08-20
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Major groove (S)-alpha-(N6-adenyl)styrene oxide adducts in an oligodeoxynucleotide containing the human N-ras codon 61 sequence: conformations of the S(61,2) and S(61,3) sequence isomers from 1H NMR.
Biochemistry, 35, 1996
1AGZ
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THE SOLUTION NMR STRUCTURE OF AN (R)-A-(N6-ADENYL)-STYRENE OXIDE-RAS61 OLIGODEOXYNUCLEOTIDE MODIFIED AT THE THIRD POSITION OF THE CODON 61 REGION, MINIMIZED AVERAGE STRUCTURE
Descriptor:DNA (5'-D(*CP*GP*GP*AP*CP*AP*RP*GP*AP*AP*G)-3'), DNA (5'-D(*CP*TP*TP*CP*TP*TP*GP*TP*CP*CP*G)-3')
Authors:Feng, B., Stone, M.P.
Deposit date:1997-03-26
Release date:1997-08-20
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Major groove (R)-alpha-(N6-adenyl)styrene oxide adducts in an oligodeoxynucleotide containing the human N-ras codon 61 sequence: conformations of the R(61,2) and R(61,3) sequence isomers from 1H NMR.
Biochemistry, 34, 1995
2M0X
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SOLUTION STRUCTURE OF U14UB1, AN ENGINEERED UBIQUITIN VARIANT WITH INCREASED AFFINITY FOR USP14
Descriptor:engineered ubiquitin variant
Authors:Phillips, A.H., Fairbrother, W.J., Corn, J.E.
Deposit date:2012-11-08
Release date:2013-06-26
Last modified:2016-04-27
Method:SOLUTION NMR
Cite:Conformational dynamics control ubiquitin-deubiquitinase interactions and influence in vivo signaling.
Proc.Natl.Acad.Sci.USA, 110, 2013
2QIF
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CRYSTAL STRUCTURE OF A METALLOCHAPERONE WITH A TETRANUCLEAR CU(I) CLUSTER
Descriptor:Copper chaperone copZ, COPPER (I) ION, ACETATE ION, ...
Authors:West, C., Singleton, C., Kihlken, M.A., Le Brun, N.E., Hemmings, A.M.
Deposit date:2007-07-04
Release date:2008-07-08
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:A tetranuclear Cu(I) cluster in the metallochaperone protein CopZ.
Biochemistry, 48, 2009
3H42
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CRYSTAL STRUCTURE OF PCSK9 IN COMPLEX WITH FAB FROM LDLR COMPETITIVE ANTIBODY
Descriptor:Proprotein convertase subtilisin/kexin type 9, Fab from LDLR competitive antibody: Light chain, Fab from LDLR competitive antibody: Heavy chain, ...
Authors:Piper, D.E., Walker, N.P.C., Romanow, W.G., Thibault, S.T., Tsai, M.M., Yang, E.
Deposit date:2009-04-17
Release date:2009-05-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:From the Cover: A proprotein convertase subtilisin/kexin type 9 neutralizing antibody reduces serum cholesterol in mice and nonhuman primates.
Proc.Natl.Acad.Sci.USA, 106, 2009
3TTK
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CRYSTAL STRUCTURE OF APO-SPUD
Descriptor:Polyamine transport protein
Authors:Wu, D.H., Lim, S.C., Song, H.W.
Deposit date:2011-09-14
Release date:2012-03-28
Method:X-RAY DIFFRACTION (2.97 Å)
Cite:Structural Basis of Substrate Binding Specificity Revealed by the Crystal Structures of Polyamine Receptors SpuD and SpuE from Pseudomonas aeruginosa
J.Mol.Biol., 416, 2012
3TTL
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CRYSTAL STRUCTURE OF APO-SPUE
Descriptor:Polyamine transport protein
Authors:Wu, D.H., Lim, S.C., Song, H.W.
Deposit date:2011-09-14
Release date:2012-03-28
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Basis of Substrate Binding Specificity Revealed by the Crystal Structures of Polyamine Receptors SpuD and SpuE from Pseudomonas aeruginosa
J.Mol.Biol., 416, 2012
3TTM
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CRYSTAL STRUCTURE OF SPUD IN COMPLEX WITH PUTRESCINE
Descriptor:Polyamine transport protein, 1,4-DIAMINOBUTANE
Authors:Wu, D.H., Lim, S.C., Song, H.W.
Deposit date:2011-09-15
Release date:2012-03-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Basis of Substrate Binding Specificity Revealed by the Crystal Structures of Polyamine Receptors SpuD and SpuE from Pseudomonas aeruginosa
J.Mol.Biol., 416, 2012
3TTN
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CRYSTAL STRUCTURES OF POLYAMINE RECEPTORS SPUD AND SPUE FROM PSEUDOMONAS AERUGINOSA
Descriptor:Polyamine transport protein, SPERMIDINE
Authors:Lim, S.C., Wu, D.H., Song, H.W.
Deposit date:2011-09-15
Release date:2012-03-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Basis of Substrate Binding Specificity Revealed by the Crystal Structures of Polyamine Receptors SpuD and SpuE from Pseudomonas aeruginosa
J.Mol.Biol., 416, 2012
4AIF
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AIP TPR DOMAIN IN COMPLEX WITH HUMAN HSP90 PEPTIDE
Descriptor:AH RECEPTOR-INTERACTING PROTEIN, HEAT SHOCK PROTEIN HSP 90-ALPHA, SULFATE ION
Authors:Morgan, R.M.L., Roe, S.M., Pearl, L.H., Prodromou, C.
Deposit date:2012-02-09
Release date:2013-01-23
Method:X-RAY DIFFRACTION (2.006 Å)
Cite:Structure of the Tpr Domain of Aip: Lack of Client Protein Interaction with the C-Terminal Alpha-7 Helix of the Tpr Domain of Aip is Sufficient for Pituitary Adenoma Predisposition.
Plos One, 7, 2012
4APO
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AIP TPR DOMAIN IN COMPLEX WITH HUMAN TOMM20 PEPTIDE
Descriptor:AH RECEPTOR-INTERACTING PROTEIN, MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM20 HOMOLOG, DODECAETHYLENE GLYCOL, ...
Authors:Morgan, R.M.L., Roe, S.M., Pearl, L.H., Prodromou, C.
Deposit date:2012-04-04
Release date:2013-01-23
Method:X-RAY DIFFRACTION (1.895 Å)
Cite:Structure of the Tpr Domain of Aip: Lack of Client Protein Interaction with the C-Terminal Alpha-7 Helix of the Tpr Domain of Aip is Sufficient for Pituitary Adenoma Predisposition.
Plos One, 7, 2012
4EJF
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ALLOSTERIC PEPTIDES THAT BIND TO A CASPASE ZYMOGEN AND MEDIATE CASPASE TETRAMERIZATION
Descriptor:Caspase-6, phage-derived peptide 419, PHOSPHATE ION
Authors:Murray, J.M.
Deposit date:2012-04-06
Release date:2012-06-20
Last modified:2012-09-05
Method:X-RAY DIFFRACTION (2.6465 Å)
Cite:Allosteric peptides bind a caspase zymogen and mediate caspase tetramerization.
Nat.Chem.Biol., 8, 2012
4NMX
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PCSK9(DELTACRD) IN COMPLEX WITH PHAGE-DERIVED INHIBITORY PEPTIDE 2-8
Descriptor:Proprotein convertase subtilisin/kexin type 9, peptide 2-8
Authors:Eigenbrot, C., Shia, S.
Deposit date:2013-11-15
Release date:2013-12-04
Last modified:2014-01-29
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Identification of a Small Peptide That Inhibits PCSK9 Protein Binding to the Low Density Lipoprotein Receptor.
J.Biol.Chem., 289, 2014
4YN7
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NON-OXIDIZED YFIR
Descriptor:YfiR, SULFATE ION
Authors:Yang, X., Jiang, T.
Deposit date:2015-03-09
Release date:2015-04-22
Last modified:2015-05-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structures of YfiR from Pseudomonas aeruginosa in two redox states
Biochem.Biophys.Res.Commun., 461, 2015
4YN9
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YFIR MUTANT-C110S
Descriptor:YfiR, SULFATE ION
Authors:Xu, M., Jiang, T.
Deposit date:2015-03-09
Release date:2015-04-22
Last modified:2015-05-20
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Crystal structures of YfiR from Pseudomonas aeruginosa in two redox states
Biochem.Biophys.Res.Commun., 461, 2015
4YNA
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OXIDIZED YFIR
Descriptor:YfiR, SULFATE ION
Authors:Xu, M., Jiang, T.
Deposit date:2015-03-09
Release date:2015-04-22
Last modified:2015-05-20
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structures of YfiR from Pseudomonas aeruginosa in two redox states
Biochem.Biophys.Res.Commun., 461, 2015
5H31
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STRUCTURAL BASIS FOR DIMERIZATION OF THE DEATH EFFECTOR DOMAINS OF CASPASE-8
Descriptor:Caspase-8
Authors:Shen, C., Pei, J., Guo, X., Quan, J.
Deposit date:2016-10-19
Release date:2017-10-25
Method:X-RAY DIFFRACTION (3.169535 Å)
Cite:Structural basis for dimerization of the death effector domains of Caspase-8
To Be Published
5H33
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STRUCTURAL BASIS FOR DIMERIZATION OF THE DEATH EFFECTOR DOMAINS OF CASPASE-8
Descriptor:Caspase-8
Authors:Shen, C., Pei, J., Guo, X., Quan, J.
Deposit date:2016-10-20
Release date:2017-10-25
Method:X-RAY DIFFRACTION (3.600138 Å)
Cite:Structural basis for dimerization of the death effector domains of Caspase-8
To Be Published
5IT3
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SWIRM DOMAIN OF HUMAN LSD1
Descriptor:Lysine-specific histone demethylase 1A, MAGNESIUM ION
Authors:Jeffrey, P.D., Yuan, P.
Deposit date:2016-03-16
Release date:2016-05-18
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:A Tlx-interacting peptide of Lsd1 inhibits the proliferation of brain tumor stem cells
To Be Published
5UX3
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RNA HAIRPIN STRUCTURE CONTAINING 2-MEIMPG MONOMER ANALOGUE AND 2-MEIMP-OLIGOMER ANALOGUE
Descriptor:RNA (25-MER), RNA (5'-D(*(RG))-R(P*CP*AP*CP*CP*UP*CP*A)-3'), 5'-O-[(S)-hydroxy(4-methyl-1H-imidazol-5-yl)phosphoryl]guanosine
Authors:Zhang, W., Oh, S.S., Szostak, J.W.
Deposit date:2017-02-21
Release date:2018-02-21
Last modified:2018-03-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Rationale for the Enhanced Catalysis of Nonenzymatic RNA Primer Extension by a Downstream Oligonucleotide.
J. Am. Chem. Soc., 140, 2018
5UZ6
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RNA HAIRPIN STRUCTURE CONTAINING 2-MEIMP-OLIGO ANALOGUE
Descriptor:RNA (25-MER), RNA (5'-D(*(8OS))-R(P*CP*AP*CP*CP*UP*CP*A)-3')
Authors:Zhang, W., Oh, S.S., Szostak, J.W.
Deposit date:2017-02-24
Release date:2018-02-21
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Rationale for the Enhanced Catalysis of Nonenzymatic RNA Primer Extension by a Downstream Oligonucleotide.
J. Am. Chem. Soc., 140, 2018
5V0H
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RNA DUPLEX WITH 2-MEIMPG ANALOGUE BOUND-ONE BINDING SITE
Descriptor:RNA (5'-R(*(LCC)P*(LCC)P*(LCC)P*(LCG)P*AP*CP*UP*UP*AP*AP*GP*UP*CP*GP*G)-3'), 5'-O-[(S)-hydroxy(4-methyl-1H-imidazol-5-yl)phosphoryl]guanosine, MAGNESIUM ION
Authors:Zhang, W., Tam, C.P., Szostak, J.W.
Deposit date:2017-02-28
Release date:2017-03-08
Last modified:2018-03-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Rationale for the Enhanced Catalysis of Nonenzymatic RNA Primer Extension by a Downstream Oligonucleotide.
J. Am. Chem. Soc., 140, 2018
5V0J
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RNA DUPLEX WITH 2-MEIMPG ANALOGUE BOUND-2 BINDING SITES
Descriptor:RNA (5'-R(*(LCC)P*(LCC)P*(LCA)P*(LCG)P*AP*CP*UP*UP*AP*AP*GP*UP*CP*U)-3'), 5'-O-[(S)-hydroxy(4-methyl-1H-imidazol-5-yl)phosphoryl]guanosine, MAGNESIUM ION
Authors:Zhang, W., Tam, C.P., Szostak, J.W.
Deposit date:2017-02-28
Release date:2017-03-08
Last modified:2018-03-14
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural Rationale for the Enhanced Catalysis of Nonenzymatic RNA Primer Extension by a Downstream Oligonucleotide.
J. Am. Chem. Soc., 140, 2018