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3QQ8
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CRYSTAL STRUCTURE OF P97-N IN COMPLEX WITH FAF1-UBX
Descriptor:Transitional endoplasmic reticulum ATPase, FAS-associated factor 1, CHLORIDE ION
Authors:Haenzelmann, P., Schindelin, H.
Deposit date:2011-02-15
Release date:2011-06-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Hierarchical Binding of Cofactors to the AAA ATPase p97.
Structure, 19, 2011
3R3M
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CRYSTAL STRUCTURE OF THE FAF1 UBX DOMAIN
Descriptor:FAS-associated factor 1, PHOSPHATE ION
Authors:Haenzelmann, P., Schindelin, H.
Deposit date:2011-03-16
Release date:2011-06-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Hierarchical Binding of Cofactors to the AAA ATPase p97.
Structure, 19, 2011
3TIW
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CRYSTAL STRUCTURE OF P97N IN COMPLEX WITH THE C-TERMINUS OF GP78
Descriptor:Transitional endoplasmic reticulum ATPase, E3 ubiquitin-protein ligase AMFR, CHLORIDE ION
Authors:Haenzelmann, P., Schindelin, H.
Deposit date:2011-08-22
Release date:2011-09-14
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (1.802 Å)
Cite:The Structural and Functional Basis of the p97/Valosin-containing Protein (VCP)-interacting Motif (VIM): MUTUALLY EXCLUSIVE BINDING OF COFACTORS TO THE N-TERMINAL DOMAIN OF p97.
J.Biol.Chem., 286, 2011
4BKM
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CRYSTAL STRUCTURE OF THE MURINE AUM (PHOSPHOGLYCOLATE PHOSPHATASE) CAPPING DOMAIN AS A FUSION PROTEIN WITH THE CATALYTIC CORE DOMAIN OF MURINE CHRONOPHIN (PYRIDOXAL PHOSPHATE PHOSPHATASE)
Descriptor:PYRIDOXAL PHOSPHATE PHOSPHATASE, PHOSPHOGLYCOLATE PHOSPHATASE, MAGNESIUM ION, ...
Authors:Knobloch, G., Seifried, A., Gohla, A., Schindelin, H.
Deposit date:2013-04-26
Release date:2013-12-25
Last modified:2017-06-28
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Evolutionary and Structural Analyses of the Mammalian Haloacid Dehalogenase-Type Phosphatases Aum and Chronophin Provide Insight Into the Basis of Their Different Substrate Specificities.
J.Biol.Chem., 289, 2014
4BX0
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CRYSTAL STRUCTURE OF A MONOMERIC VARIANT OF MURINE CHRONOPHIN (PYRIDOXAL PHOSPHATE PHOSPHATASE)
Descriptor:PYRIDOXAL PHOSPHATE PHOSPHATASE, MAGNESIUM ION, GLYCEROL
Authors:Kestler, C., Knobloch, G., Gohla, A., Schindelin, H.
Deposit date:2013-07-08
Release date:2013-12-25
Last modified:2014-02-12
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Chronophin Dimerization is Required for Proper Positioning of its Substrate Specificity Loop
J.Biol.Chem., 289, 2014
4BX2
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CRYSTAL STRUCTURE OF MURINE CHRONOPHIN (PYRIDOXAL PHOSPHATE PHOSPHATASE) IN COMPLEX WITH BERYLLIUM TRIFLUORIDE
Descriptor:PYRIDOXAL PHOSPHATE PHOSPHATASE, MAGNESIUM ION, BERYLLIUM TRIFLUORIDE ION, ...
Authors:Knobloch, G., Gohla, A., Schindelin, H.
Deposit date:2013-07-08
Release date:2013-12-25
Last modified:2014-02-12
Method:X-RAY DIFFRACTION (2.193 Å)
Cite:Chronophin Dimerization is Required for Proper Positioning of its Substrate Specificity Loop.
J.Biol.Chem., 289, 2014
4BX3
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CRYSTAL STRUCTURE OF MURINE CHRONOPHIN (PYRIDOXAL PHOSPHATE PHOSPHATASE)
Descriptor:PYRIDOXAL PHOSPHATE PHOSPHATASE, MAGNESIUM ION, GLYCEROL
Authors:Knobloch, G., Gohla, A., Schindelin, H.
Deposit date:2013-07-08
Release date:2013-12-25
Last modified:2014-02-12
Method:X-RAY DIFFRACTION (2.193 Å)
Cite:Chronophin Dimerization is Required for Proper Positioning of its Substrate Specificity Loop.
J.Biol.Chem., 289, 2014
4F9Z
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CRYSTAL STRUCTURE OF HUMAN ERP27
Descriptor:Endoplasmic reticulum resident protein 27, ACETATE ION, 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL, ...
Authors:Kober, F.X., Koelmel, W., Kuper, J., Schindelin, H.
Deposit date:2012-05-21
Release date:2012-12-05
Last modified:2013-02-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The Crystal Structure of the Protein-Disulfide Isomerase Family Member ERp27 Provides Insights into Its Substrate Binding Capabilities.
J.Biol.Chem., 288, 2013
4MT6
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CRYSTAL STRUCTURE OF CLOSED INACTIVE COLLYBISTIN
Descriptor:Rho guanine nucleotide exchange factor 9
Authors:Schneeberger, D., Schindelin, H.
Deposit date:2013-09-19
Release date:2014-08-13
Last modified:2014-10-01
Method:X-RAY DIFFRACTION (5.501 Å)
Cite:A conformational switch in collybistin determines the differentiation of inhibitory postsynapses.
Embo J., 33, 2014
4MT7
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CRYSTAL STRUCTURE OF COLLYBISTIN I
Descriptor:Rho guanine nucleotide exchange factor 9
Authors:Schneeberger, D., Schindelin, H.
Deposit date:2013-09-19
Release date:2014-08-13
Last modified:2014-10-01
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:A conformational switch in collybistin determines the differentiation of inhibitory postsynapses.
Embo J., 33, 2014
4NNJ
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CRYSTAL STRUCTURE OF UBA1 IN COMPLEX WITH UBIQUITIN-AMP AND THIOESTERIFIED UBIQUITIN
Descriptor:Ubiquitin-activating enzyme E1 1, Uba1, SULFATE ION, ...
Authors:Schaefer, A., Schindelin, H.
Deposit date:2013-11-18
Release date:2014-05-07
Last modified:2014-09-24
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of the ubiquitin-activating enzyme loaded with two ubiquitin molecules.
Acta Crystallogr.,Sect.D, 70, 2014
4OYU
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CRYSTAL STRUCTURE OF THE N-TERMINAL DOMAINS OF MUSKELIN
Descriptor:Muskelin, 1,2-ETHANEDIOL, GLYCEROL
Authors:Delto, C., Kuper, J., Schindelin, H.
Deposit date:2014-02-13
Release date:2015-02-11
Last modified:2015-03-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The LisH Motif of Muskelin Is Crucial for Oligomerization and Governs Intracellular Localization.
Structure, 23, 2015
4PD0
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1.7 A RESOLUTION STRUCTURE OF GEPHYRIN'S E-DOMAIN
Descriptor:Gephyrin
Authors:Kasaragod, V.B., Maric, H.M., Schindelin, H.
Deposit date:2014-04-17
Release date:2014-08-27
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Modulation of gephyrin-glycine receptor affinity by multivalency.
Acs Chem.Biol., 9, 2014
4PD1
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STRUCTURE OF GEPHYRIN E DOMAIN WITH GLYCINE-BETA RECEPTOR PEPTIDE
Descriptor:Gephyrin, Glycine receptor subunit beta, GLYCEROL, ...
Authors:Kasaragod, V.B., Maric, H.M., Schindelin, H.
Deposit date:2014-04-17
Release date:2014-08-27
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (1.975 Å)
Cite:Modulation of gephyrin-glycine receptor affinity by multivalency.
Acs Chem.Biol., 9, 2014
4TK1
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GEPH E IN COMPLEX WITH A GABA RECEPTOR ALPHA3 SUBUNIT DERIVED PEPTIDE IN SPACE GROUP P21212
Descriptor:Gephyrin, Gamma-aminobutyric acid receptor subunit alpha-3, GLYCEROL, ...
Authors:Kasaragod, V.B., Maric, H.M., Schindelin, H.
Deposit date:2014-05-25
Release date:2014-12-24
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Molecular basis of the alternative recruitment of GABAA versus glycine receptors through gephyrin.
Nat Commun, 5, 2014
4TK2
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GEPH E IN COMPLEX WITH A GABA RECEPTOR ALPHA3 SUBUNIT DERIVED PEPTIDE IN SPACE GROUP P61
Descriptor:Gephyrin, Gamma-aminobutyric acid receptor subunit alpha-3
Authors:Kasaragod, V.B., Maric, H.M., Schindelin, H.
Deposit date:2014-05-25
Release date:2014-12-24
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (4.1 Å)
Cite:Molecular basis of the alternative recruitment of GABAA versus glycine receptors through gephyrin.
Nat Commun, 5, 2014
4TK3
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GEPH E IN COMPLEX WITH A GABA RECEPTOR ALPHA3 DERIVED DOUBLE MUTANT PEPTIDE IN SPACEGROUP P21212
Descriptor:Gephyrin, Gamma-aminobutyric acid receptor subunit alpha-3
Authors:Kasaragod, V.B., Maric, H.M., Schindelin, H.
Deposit date:2014-05-25
Release date:2014-12-24
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Molecular basis of the alternative recruitment of GABAA versus glycine receptors through gephyrin.
Nat Commun, 5, 2014
4TK4
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GEPHE IN COMPLEX WITH A GABA RECEPTOR ALPHA3 SUBUNIT DERIVED DOUBLE MUTANT PEPTIDE IN SPACE GROUP P61
Descriptor:Gephyrin, Gamma-aminobutyric acid receptor subunit alpha-3
Authors:Kasaragod, V.B., Maric, H.M., Schindelin, H.
Deposit date:2014-05-25
Release date:2014-12-24
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (3.601 Å)
Cite:Molecular basis of the alternative recruitment of GABAA versus glycine receptors through gephyrin.
Nat Commun, 5, 2014
4U90
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GEPHE IN COMPLEX WITH PEG CROSSLINKED GABA RECEPTOR ALPHA3 SUBUNIT DERIVED DIMERIC PEPTIDE
Descriptor:Gephyrin, Gamma-aminobutyric acid receptor subunit alpha-3, 1,4-BUTANEDIOL, ...
Authors:Kasaragod, V.B., Maric, H.M., Schindelin, H.
Deposit date:2014-08-05
Release date:2014-12-10
Last modified:2015-02-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Design and Synthesis of High-Affinity Dimeric Inhibitors Targeting the Interactions between Gephyrin and Inhibitory Neurotransmitter Receptors.
Angew.Chem.Int.Ed.Engl., 54, 2015
4U91
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GEPHE IN COMPLEX WITH PARA-PHENYL CROSSLINKED GLYCINE RECEPTOR BETA SUBUNIT DERIVED DIMERIC PEPTIDE
Descriptor:Gephyrin, Glycine receptor subunit beta, ACETATE ION, ...
Authors:Kasaragod, V.B., Maric, H.M., Schindelin, H.
Deposit date:2014-08-05
Release date:2014-12-10
Last modified:2015-02-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Design and Synthesis of High-Affinity Dimeric Inhibitors Targeting the Interactions between Gephyrin and Inhibitory Neurotransmitter Receptors.
Angew.Chem.Int.Ed.Engl., 54, 2015
5AES
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CRYSTAL STRUCTURE OF MURINE CHRONOPHIN (PYRIDOXAL PHOSPHATE PHOSPHATASE) IN COMPLEX WITH A PNP-DERIVED INHIBITOR
Descriptor:PYRIDOXAL PHOSPHATE PHOSPHATASE, MAGNESIUM ION, {2-[5-hydroxy-4-(hydroxymethyl)-6-methylpyridin-3-yl]ethyl}phosphonic acid, ...
Authors:Knobloch, G., Jabari, N., Koehn, M., Gohla, A., Schindelin, H.
Deposit date:2015-01-09
Release date:2015-04-01
Last modified:2017-06-28
Method:X-RAY DIFFRACTION (2.751 Å)
Cite:Synthesis of Hydrolysis-Resistant Pyridoxal 5'-Phosphate Analogs and Their Biochemical and X-Ray Crystallographic Characterization with the Pyridoxal Phosphatase Chronophin.
Bioorg.Med.Chem., 23, 2015
5C18
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P97-DELTA709-728 IN COMPLEX WITH ATP-GAMMA-S
Descriptor:Transitional endoplasmic reticulum ATPase, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, MAGNESIUM ION, ...
Authors:Haenzelmann, P., Schindelin, H.
Deposit date:2015-06-13
Release date:2016-01-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural Basis of ATP Hydrolysis and Intersubunit Signaling in the AAA+ ATPase p97.
Structure, 24, 2016
5C19
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P97 VARIANT 2 IN THE APO STATE
Descriptor:Transitional endoplasmic reticulum ATPase, SULFATE ION
Authors:Haenzelmann, P., Schindelin, H.
Deposit date:2015-06-13
Release date:2016-01-13
Last modified:2016-01-20
Method:X-RAY DIFFRACTION (4.2 Å)
Cite:Structural Basis of ATP Hydrolysis and Intersubunit Signaling in the AAA+ ATPase p97.
Structure, 24, 2016
5C1A
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P97-N750D/R753D/M757D/Q760D IN COMPLEX WITH ATP-GAMMA-S
Descriptor:Transitional endoplasmic reticulum ATPase, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, MAGNESIUM ION
Authors:Haenzelmann, P., Schindelin, H.
Deposit date:2015-06-13
Release date:2016-01-13
Last modified:2016-01-20
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Structural Basis of ATP Hydrolysis and Intersubunit Signaling in the AAA+ ATPase p97.
Structure, 24, 2016
5C1B
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P97-DELTA709-728 IN COMPLEX WITH A UFD1-SHP PEPTIDE
Descriptor:Transitional endoplasmic reticulum ATPase, Ubiquitin fusion degradation protein 1 homolog, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
Authors:Haenzelmann, P., Schindelin, H.
Deposit date:2015-06-13
Release date:2016-01-13
Last modified:2016-01-20
Method:X-RAY DIFFRACTION (3.08 Å)
Cite:Characterization of an Additional Binding Surface on the p97 N-Terminal Domain Involved in Bipartite Cofactor Interactions.
Structure, 24, 2016