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3FMS
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CRYSTAL STRUCTURE OF TM0439, A GNTR TRANSCRIPTIONAL REGULATOR
Descriptor:Transcriptional regulator, GntR family, NICKEL (II) ION, ...
Authors:Zheng, M., Cooper, D.R., Yu, M., Hung, L.-W., Derewenda, U., Derewenda, Z.S., Integrated Center for Structure and Function Innovation (ISFI)
Deposit date:2008-12-22
Release date:2009-02-10
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of Thermotoga maritima TM0439: implications for the mechanism of bacterial GntR transcription regulators with Zn2+-binding FCD domains.
Acta Crystallogr.,Sect.D, 65, 2009
3HD0
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CRYSTAL STRUCTURE OF TM1865, AN ENDONUCLEASE V FROM THERMOTOGA MARITIMA
Descriptor:Endonuclease V
Authors:Utepbergenov, D., Cooper, D.R., Derewenda, U., Derewenda, Z.S., Integrated Center for Structure and Function Innovation (ISFI)
Deposit date:2009-05-06
Release date:2009-07-14
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of Tm1865, an Endonuclease V from Thermotoga Maritima
To be Published
3MSX
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CRYSTAL STRUCTURE OF RHOA.GDP.MGF3 IN COMPLEX WITH GAP DOMAIN OF ARHGAP20
Descriptor:Transforming protein RhoA, Rho GTPase-activating protein 20, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Utepbergenov, D., Cooper, D.R., Derewenda, U., Derewenda, Z.S.
Deposit date:2010-04-29
Release date:2011-03-16
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Mechanism of molecular specificity of RhoGAP domains towards small GTPases of RhoA family.
To be Published
3N77
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CRYSTAL STRUCTURE OF IDP01880, PUTATIVE NTP PYROPHOSPHOHYDROLASE OF SALMONELLA TYPHIMURIUM LT2
Descriptor:Nucleoside triphosphatase nudI
Authors:Frydrysiak, J., Cooper, D.R., Derewenda, U., Anderson, W.F., Derewenda, Z.S., Integrated Center for Structure and Function Innovation (ISFI), Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2010-05-26
Release date:2010-08-18
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Crystal structure of Idp01880, putative NTP pyrophosphohydrolase of Salmonella typhimurium LT2
To be Published
3SXK
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ZN2+-BOUND FCD DOMAIN OF TM0439, A PUTATIVE TRANSCRIPTIONAL REGULATOR
Descriptor:Transcriptional regulator, GntR family, SULFATE ION, ...
Authors:Czelakowski, G.P., Derewenda, Z.S., Integrated Center for Structure and Function Innovation (ISFI)
Deposit date:2011-07-15
Release date:2011-11-16
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Zn2+-bound FCD domain of TM0439, a putative transcriptional regulator
To be Published
3SXM
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METAL-FREE FCD DOMAIN OF TM0439 A PUTATIVE TRANSCRIPTIONAL REGULATOR
Descriptor:Transcriptional regulator, GntR family, BICARBONATE ION
Authors:Czelakowski, G.P., Derewenda, Z.S., Integrated Center for Structure and Function Innovation (ISFI)
Deposit date:2011-07-15
Release date:2011-11-16
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Metal-free FCD domain of TM0439 a putative transcriptional regulator
To be Published
3SXY
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METAL-FREE FULL-LENGTH STRUCTURE OF TM0439, A METAL-BINDING FCD FAMILY TRANSCRIPTIONAL REGULATOR
Descriptor:Transcriptional regulator, GntR family
Authors:Czelakowski, G.P., Derewenda, Z.S., Integrated Center for Structure and Function Innovation (ISFI)
Deposit date:2011-07-15
Release date:2011-11-16
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.647 Å)
Cite:Metal-free full-length structure of Tm0439, a metal-binding FCD family transcriptional regulator
To be Published
3SXZ
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METAL-FREE FCD DOMAIN OF TM0439 A PUTATIVE TRANSCRIPTIONAL REGULATOR
Descriptor:Transcriptional regulator, GntR family
Authors:Czelakowski, G.P., Derewenda, Z.S., Integrated Center for Structure and Function Innovation (ISFI)
Deposit date:2011-07-15
Release date:2011-11-16
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.322 Å)
Cite:Metal-free FCD domain of TM0439 a putative transcriptional regulator
To be Published
3T06
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CRYSTAL STRUCTURE OF THE DH/PH FRAGMENT OF PDZRHOGEF WITH N-TERMINAL REGULATORY ELEMENTS IN COMPLEX WITH HUMAN RHOA
Descriptor:Rho guanine nucleotide exchange factor 11, Transforming protein RhoA
Authors:Bielnicki, J.A., Derewenda, U., Derewenda, Z.S.
Deposit date:2011-07-19
Release date:2011-08-03
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.84 Å)
Cite:Insights into the Molecular Activation Mechanism of the RhoA-specific Guanine Nucleotide Exchange Factor, PDZRhoGEF.
J.Biol.Chem., 286, 2011
3UBD
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STRUCTURE OF N-TERMINAL DOMAIN OF RSK2 KINASE IN COMPLEX WITH FLAVONOID GLYCOSIDE SL0101
Descriptor:Ribosomal protein S6 kinase alpha-3, 5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-3-yl 3,4-di-O-acetyl-6-deoxy-alpha-L-mannopyranoside
Authors:Utepbergenov, D., Derewenda, U., Derewenda, Z.S.
Deposit date:2011-10-24
Release date:2012-09-05
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:Insights into the Inhibition of the p90 Ribosomal S6 Kinase (RSK) by the Flavonol Glycoside SL0101 from the 1.5 A Crystal Structure of the N-Terminal Domain of RSK2 with Bound Inhibitor.
Biochemistry, 51, 2012
4EL9
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STRUCTURE OF N-TERMINAL KINASE DOMAIN OF RSK2 WITH AFZELIN
Descriptor:Ribosomal protein S6 kinase alpha-3, 5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-3-yl 6-deoxy-alpha-L-mannopyranoside
Authors:Utepbergenov, D., Derewenda, U., Derewenda, Z.S.
Deposit date:2012-04-10
Release date:2012-09-05
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Insights into the Inhibition of the p90 Ribosomal S6 Kinase (RSK) by the Flavonol Glycoside SL0101 from the 1.5 A Crystal Structure of the N-Terminal Domain of RSK2 with Bound Inhibitor.
Biochemistry, 51, 2012
4GUE
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STRUCTURE OF N-TERMINAL KINASE DOMAIN OF RSK2 WITH FLAVONOID GLYCOSIDE QUERCITRIN
Descriptor:Ribosomal protein S6 kinase alpha-3, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-3-yl 6-deoxy-alpha-L-mannopyranoside, MAGNESIUM ION, ...
Authors:Derewenda, U., Utepbergenov, D., Szukalska, G., Derewenda, Z.S.
Deposit date:2012-08-29
Release date:2013-01-30
Last modified:2013-03-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Identification of quercitrin as an inhibitor of the p90 S6 ribosomal kinase (RSK): structure of its complex with the N-terminal domain of RSK2 at 1.8 A resolution.
Acta Crystallogr.,Sect.D, 69, 2013
4QAZ
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THE CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF EBOLA (ZAIRE) NUCLEOPROTEIN
Descriptor:Nucleoprotein
Authors:Derewenda, U., Dziubanska, P.J., Derewenda, Z.S.
Deposit date:2014-05-06
Release date:2014-09-10
Last modified:2014-09-24
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:The structure of the C-terminal domain of the Zaire ebolavirus nucleoprotein.
Acta Crystallogr.,Sect.D, 70, 2014
4QB0
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THE CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF EBOLA (ZAIRE) NUCLEOPROTEIN
Descriptor:Nucleoprotein
Authors:Derewenda, U., Dziubanska, P.J., Derewenda, Z.S.
Deposit date:2014-05-06
Release date:2014-09-10
Last modified:2014-09-24
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:The structure of the C-terminal domain of the Zaire ebolavirus nucleoprotein.
Acta Crystallogr.,Sect.D, 70, 2014
5VI7
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CRYSTAL STRUCTURE OF THE ZIKA VIRUS NS3 HELICASE
Descriptor:helicase, SULFATE ION
Authors:Bukrejewska, M., Derewenda, U., Derewenda, Z.S.
Deposit date:2017-04-14
Release date:2017-09-06
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (2.005 Å)
Cite:Crystal structures of the methyltransferase and helicase from the ZIKA 1947 MR766 Uganda strain.
Acta Crystallogr D Struct Biol, 73, 2017
5VIM
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CRYSTAL STRUCTURE OF THE ZIKA VIRUS NS5 METHYLTRANSFERASE.
Descriptor:Methyltransferase, S-ADENOSYLMETHIONINE, SULFATE ION
Authors:Bukrejewska, M., Derewenda, Z.S., Derewenda, U.
Deposit date:2017-04-17
Release date:2017-09-06
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structures of the methyltransferase and helicase from the ZIKA 1947 MR766 Uganda strain.
Acta Crystallogr D Struct Biol, 73, 2017
5VKD
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CRYSTAL STRUCTURE OF C-TERMINAL DOMAIN OF EBOLA (BUNDIBUGYO) NUCLEOPROTEIN IN COMPLEX WITH FAB FRAGMENT
Descriptor:Nucleoprotein, Fab Heavy Chain, Fab light chain
Authors:Radwanska, M.J., Derewenda, U., Kossiakoff, A., Derewenda, Z.S.
Deposit date:2017-04-21
Release date:2018-04-25
Method:X-RAY DIFFRACTION (1.749 Å)
Cite:Crystal structure of C-terminal domain of Ebola (Bundibugyo) nucleoprotein in complex with Fab fragment
To Be Published
5VZ1
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CRYSTAL STRUCTURE OF THE APO ANTIBODY FRAGMENT (FAB) RAISED AGAINST C-TERMINAL DOMAIN OF EBOLA NUCLEOPROTEIN (EBOV, TAFV, BDBV STRAINS)
Descriptor:Apo Antibody Fab Light Chain, Apo Antibody Fab Heavy Chain, ZINC ION
Authors:Radwanska, M.J., Derewenda, U., Kossiakoff, A., Derewenda, Z.S.
Deposit date:2017-05-26
Release date:2018-06-27
Method:X-RAY DIFFRACTION (2.112 Å)
Cite:Crystal structure of the Apo Antibody fragment (Fab) raised against C-terminal domain of Ebola nucleoprotein (EBOV, TAFV, BDBV strains)
To Be Published
5W2B
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CRYSTAL STRUCTURE OF C-TERMINAL DOMAIN OF EBOLA (RESTON) NUCLEOPROTEIN IN COMPLEX WITH FAB FRAGMENT
Descriptor:Fab Heavy Chain, Fab Light Chain, Nucleoprotein
Authors:Radwanska, M.J., Derewenda, U., Kossiakoff, A.A., Derewenda, Z.S.
Deposit date:2017-06-06
Release date:2018-06-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystal structure of C-terminal domain of Ebola (Reston) nucleoprotein in complex with Fab fragment
To Be Published
6B6Z
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CRYSTAL STRUCTURE OF THE APO ANTIBODY FRAGMENT (FAB) RAISED AGAINST C-TERMINAL DOMAIN OF EBOLA NUCLEOPROTEIN (EBOV, TAFV, BDBV STRAINS)
Descriptor:Apo Fab Light Chain, Apo Fab Heavy Chain, ZINC ION
Authors:Radwanska, M.J., Derewenda, U., Kossiakoff, A.A., Derewenda, Z.S.
Deposit date:2017-10-03
Release date:2018-12-19
Method:X-RAY DIFFRACTION (2.112 Å)
Cite:Crystal structure of the Apo Antibody fragment (Fab) raised against C-terminal domain of Ebola nucleoprotein (EBOV, TAFV, BDBV strains)
To Be Published
1H4R
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CRYSTAL STRUCTURE OF THE FERM DOMAIN OF MERLIN, THE NEUROFIBROMATOSIS 2 TUMOR SUPPRESSOR PROTEIN.
Descriptor:MERLIN, SULFATE ION
Authors:Cooper, D.R., Kang, B.S., Sheffield, P., Devedjiev, Y., Derewenda, Z.S.
Deposit date:2001-05-14
Release date:2002-01-16
Last modified:2019-05-15
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The Structure of the Ferm Domain of Merlin, the Neurofibromatosis Type 2 Gene Product.
Acta Crystallogr.,Sect.D, 58, 2002
1JFR
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CRYSTAL STRUCTURE OF THE STREPTOMYCES EXFOLIATUS LIPASE AT 1.9A RESOLUTION: A MODEL FOR A FAMILY OF PLATELET-ACTIVATING FACTOR ACETYLHYDROLASES
Descriptor:LIPASE
Authors:Wei, Y., Derewenda, Z.S.
Deposit date:1997-07-11
Release date:1998-07-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of a microbial homologue of mammalian platelet-activating factor acetylhydrolases: Streptomyces exfoliatus lipase at 1.9 A resolution.
Structure, 6, 1998
1W9Q
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CRYSTAL STRUCTURE OF THE PDZ TANDEM OF HUMAN SYNTENIN IN COMPLEX WITH TNEFAF PEPTIDE
Descriptor:SYNTENIN 1, TNEFAF PEPTIDE, BENZOIC ACID
Authors:Grembecka, J., Cierpicki, T., Devedjiev, Y., Cooper, D.R., Derewenda, Z.S.
Deposit date:2004-10-15
Release date:2006-03-22
Last modified:2019-01-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The Binding of the Pdz Tandem of Syntenin to Target Proteins.
Biochemistry, 45, 2006
3H3E
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CRYSTAL STRUCTURE OF TM1679, A METAL-DEPENDENT HYDROLASE OF THE BETA-LACTAMASE SUPERFAMILY
Descriptor:uncharacterized protein Tm1679, ZINC ION
Authors:Cooper, D.R., Olekhnovitch, N., Derewenda, U., Derewenda, Z.S., Integrated Center for Structure and Function Innovation (ISFI)
Deposit date:2009-04-16
Release date:2009-07-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.749 Å)
Cite:Crystal structure of Tm1679, A METAL-DEPENDENT HYDROLASE OF THE BETA-LACTAMASE SUPERFAMILY
To be Published
6TAA
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STRUCTURE AND MOLECULAR MODEL REFINEMENT OF ASPERGILLUS ORYZAE (TAKA) ALPHA-AMYLASE: AN APPLICATION OF THE SIMULATED-ANNEALING METHOD
Descriptor:ALPHA-AMYLASE, CALCIUM ION
Authors:Swift, H.J., Brady, L., Derewenda, Z.S., Dodson, E.J., Turkenburg, J.P., Wilkinson, A.J.
Deposit date:1992-08-21
Release date:1993-10-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure and molecular model refinement of Aspergillus oryzae (TAKA) alpha-amylase: an application of the simulated-annealing method.
Acta Crystallogr.,Sect.B, 47, 1991