Author results

6IN7
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CRYSTAL STRUCTURE OF ALGU IN COMPLEX WITH MUCA(CYTO)
Descriptor:Sigma factor AlgU negative regulatory protein, RNA polymerase sigma-H factor, NICOTINAMIDE
Authors:Li, S., Zhang, Q., Bartlam, M.
Deposit date:2018-10-24
Release date:2019-07-24
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Structural basis for the recognition of MucA by MucB and AlgU in Pseudomonas aeruginosa.
Febs J., 2019
4ZHY
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CRYSTAL STRUCTURE OF A BACTERIAL SIGNALLING COMPLEX
Descriptor:YfiR, YfiB, SULFATE ION, ...
Authors:Li, S., Li, T., Wang, Y., Bartlam, M.
Deposit date:2015-04-27
Release date:2016-04-27
Method:X-RAY DIFFRACTION (1.969 Å)
Cite:Structural insights into YfiR sequestering by YfiB in Pseudomonas aeruginosa PAO1
Sci Rep, 5, 2015
6MYQ
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AVIAN MITOCHONDRIAL COMPLEX II WITH FERULENOL BOUND
Descriptor:Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial, Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, ...
Authors:Berry, E.A., Huang, L.-S.
Deposit date:2018-11-02
Release date:2019-11-06
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Crystallographic studies of the binding of ligands to the ubiquinone site of mitochondrial respiratory Complex II
To be published
6MYU
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AVIAN MITOCHONDRIAL COMPLEX II CRYSTALLIZED IN THE PRESENCE OF HQNO
Descriptor:Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial, Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, ...
Authors:Berry, E.A., Huang, L.-S.
Deposit date:2018-11-02
Release date:2019-11-06
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Crystallographic studies of the binding of ligands to the Ubiquinone site of Mitochondrial Respiratory Complex II
To be published
1NH9
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CRYSTAL STRUCTURE OF A DNA BINDING PROTEIN MJA10B FROM THE HYPERTHERMOPHILE METHANOCOCCUS JANNASCHII
Descriptor:DNA-binding protein Alba
Authors:Wang, G., Bartlam, M., Guo, R., Yang, H., Xue, H., Liu, Y., Huang, L., Rao, Z.
Deposit date:2002-12-19
Release date:2003-12-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of a DNA binding protein from the hyperthermophilic euryarchaeon Methanococcus jannaschii
Protein Sci., 12, 2003
1WOF
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CRYSTAL STRUCTURE OF SARS-COV MPRO IN COMPLEX WITH AN INHIBITOR N1
Descriptor:3C-like proteinase, N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]-L-ALANYL-L-VALYL-N~1~-((1S)-4-ETHOXY-4-OXO-1-{[(3S)-2-OXOPYRROLIDIN-3-YL]METHYL}BUT-2-ENYL)-L-LEUCINAMIDE
Authors:Yang, H., Bartlam, M., Xue, X., Yang, K., Liang, W., Rao, Z.
Deposit date:2004-08-18
Release date:2005-08-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Design of Wide-Spectrum Inhibitors Targeting Coronavirus Main Proteases.
Plos Biol., 3, 2005
2HU5
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BINDING OF INHIBITORS BY ACYLAMINOACYL-PEPTIDASE
Descriptor:Acylamino-acid-releasing enzyme, GLYCINE, PHENYLALANINE, ...
Authors:Kiss, A.L., Hornung, B., Radi, K., Gengeliczki, Z., Sztaray, B., Harmat, V., Polgar, L.
Deposit date:2006-07-26
Release date:2007-05-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Acylaminoacyl Peptidase from Aeropyrum pernix K1 Thought to Be an Exopeptidase Displays Endopeptidase Activity
J.Mol.Biol., 368, 2007
2Q6F
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CRYSTAL STRUCTURE OF INFECTIOUS BRONCHITIS VIRUS (IBV) MAIN PROTEASE IN COMPLEX WITH A MICHAEL ACCEPTOR INHIBITOR N3
Descriptor:Infectious bronchitis virus (IBV) main protease, N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]ALANYL-L-VALYL-N~1~-((1R,2Z)-4-(BENZYLOXY)-4-OXO-1-{[(3R)-2-OXOPYRROLIDIN-3-YL]METHYL}BUT-2-ENYL)-L-LEUCINAMIDE
Authors:Xue, X.Y., Yang, H.T., Xue, F., Bartlam, M., Rao, Z.H.
Deposit date:2007-06-05
Release date:2008-02-12
Last modified:2015-12-02
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of two coronavirus main proteases: implications for substrate binding and antiviral drug design.
J.Virol., 82, 2008
3EWP
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COMPLEX OF SUBSTRATE ADP-RIBOSE WITH IBV NSP3 ADRP DOMAIN
Descriptor:Non-structural protein 3, ADENOSINE-5-DIPHOSPHORIBOSE
Authors:Xu, Y., Cong, L., Chen, C., Wei, L., Zhao, Q., Xu, X., Ma, Y., Bartlam, M., Rao, Z.
Deposit date:2008-10-16
Release date:2009-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structures of two coronavirus ADP-ribose-1''-monophosphatases and their complexes with ADP-Ribose: a systematic structural analysis of the viral ADRP domain.
J.Virol., 83, 2009
3VC8
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CRYSTAL STRUCTURE OF THE C-TERMINAL CYTOPLASMIC DOMAIN OF NON-STRUCTURAL PROTEIN 4 FROM MOUSE HEPATITIS VIRUS A59
Descriptor:RNA-directed RNA polymerase
Authors:Xu, X., Lou, Z., Ma, Y., Chen, X., Yang, Z., Tong, X., Zhao, Q., Xu, Y., Deng, H., Bartlam, M., Rao, Z.
Deposit date:2012-01-03
Release date:2012-01-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of the C-terminal cytoplasmic domain of non-structural protein 4 from mouse hepatitis virus A59.
Plos One, 4, 2009
5WQN
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CRYSTAL STRUCTURE OF A CARBONYL REDUCTASE FROM PSEUDOMONAS AERUGINOSA PAO1 (CONDITION II)
Descriptor:Probable dehydrogenase
Authors:Li, S., Wang, Y., Bartlam, M.
Deposit date:2016-11-27
Release date:2017-10-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure and characterization of a NAD(P)H-dependent carbonyl reductase from Pseudomonas aeruginosa PAO1.
FEBS Lett., 591, 2017
2ESW
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ATOMIC STRUCTURE OF THE N-TERMINAL SH3 DOMAIN OF MOUSE BETA PIX,P21-ACTIVATED KINASE (PAK)-INTERACTING EXCHANGE FACTOR
Descriptor:Rho guanine nucleotide exchange factor 7, MERCURY (II) ION, CHLORIDE ION
Authors:Rao, Z.
Deposit date:2005-10-27
Release date:2006-04-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Crystal structure of the N-terminal SH3 domain of mouse betaPIX, p21-activated kinase-interacting exchange factor
Biochem.Biophys.Res.Commun., 339, 2006
2FR7
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CRYSTAL STRUCTURE OF CYTOCHROME P450 CYP199A2
Descriptor:putative cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE
Authors:Rao, Z., Wong, L.L., Xu, F., Bell, S.G.
Deposit date:2006-01-19
Release date:2007-01-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Crystal structure of CYP199A2, a para-substituted benzoic acid oxidizing cytochrome P450 from Rhodopseudomonas palustris
J.Mol.Biol., 383, 2008
2HU7
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BINDING OF INHIBITORS BY ACYLAMINOACYL PEPTIDASE
Descriptor:Acylamino-acid-releasing enzyme, ACETYL GROUP, PHENYLALANINE, ...
Authors:Kiss, A.L., Hornung, B., Radi, K., Gengeliczki, Z., Sztaray, B., Harmat, V., Polgar, L.
Deposit date:2006-07-26
Release date:2007-05-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:The Acylaminoacyl Peptidase from Aeropyrum pernix K1 Thought to Be an Exopeptidase Displays Endopeptidase Activity
J.Mol.Biol., 368, 2007
3EWR
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COMPLEX OF SUBSTRATE ADP-RIBOSE WITH HCOV-229E NSP3 ADRP DOMAIN
Descriptor:Non-structural protein 3, ADENOSINE-5-DIPHOSPHORIBOSE
Authors:Xu, Y., Cong, L., Chen, C., Wei, L., Zhao, Q., Xu, X., Ma, Y., Bartlam, M., Rao, Z.
Deposit date:2008-10-16
Release date:2009-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Crystal structures of two coronavirus ADP-ribose-1''-monophosphatases and their complexes with ADP-Ribose: a systematic structural analysis of the viral ADRP domain.
J.Virol., 83, 2009
3FAO
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CRYSTAL STRUCTURE OF S118A MUTANT 3CLSP OF PRRSV
Descriptor:Non-structural protein, PHOSPHATE ION
Authors:Gao, F., Peng, H., Tian, X., Lu, G., Liu, Y., Gao, G.F.
Deposit date:2008-11-17
Release date:2009-10-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Structure and cleavage specificity of the chymotrypsin-like serine protease (3CLSP/nsp4) of Porcine Reproductive and Respiratory Syndrome Virus (PRRSV).
J.Mol.Biol., 392, 2009
3HUI
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CRYSTAL STRUCTURE OF THE MUTANT A105R OF [2FE-2S] FERREDOXIN IN THE CLASS I CYP199A2 SYSTEM FROM RHODOPSEUDOMONAS PALUSTRIS
Descriptor:Ferredoxin, FE2/S2 (INORGANIC) CLUSTER
Authors:Bell, S.G., Xu, F., Rao, Z., Wong, L.-L.
Deposit date:2009-06-14
Release date:2010-02-09
Last modified:2014-02-12
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Protein recognition in ferredoxin-P450 electron transfer in the class I CYP199A2 system from Rhodopseudomonas palustris
J.Biol.Inorg.Chem., 15, 2010
4R0S
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CRYSTAL STRUCTURE OF P. AERUGINOSA TPBA
Descriptor:Protein tyrosine phosphatase TpbA, PHOSPHATE ION, GLYCEROL
Authors:Xu, K., Li, S., Wang, Y., Bartlam, M.
Deposit date:2014-08-01
Release date:2015-05-06
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Structural and Biochemical Analysis of Tyrosine Phosphatase Related to Biofilm Formation A (TpbA) from the Opportunistic Pathogen Pseudomonas aeruginosa PAO1
PLoS ONE, 10, 2015
5DV2
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CRYSTAL STRUCTURE OF HUMAN CNOT6L IN COMPLEX WITH CYTIDINE-5'-MONOPHOSPHATE
Descriptor:CCR4-NOT transcription complex subunit 6-like, CYTIDINE-5'-MONOPHOSPHATE
Authors:Zhang, Q., Bartlam, M.
Deposit date:2015-09-21
Release date:2016-05-18
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Structural basis for inhibition of the deadenylase activity of human CNOT6L
Febs Lett., 590, 2016
1J1L
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CRYSTAL STRUCTURE OF HUMAN PIRIN: A BCL-3 AND NUCLEAR FACTOR I INTERACTING PROTEIN AND A CUPIN SUPERFAMILY MEMBER
Descriptor:Pirin, FE (II) ION
Authors:Pang, H., Bartlam, M., Zeng, Q., Gao, G.F., Rao, Z.
Deposit date:2002-12-10
Release date:2003-12-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of human pirin: an iron-binding nuclear protein and transcription cofactor
J.Biol.Chem., 279, 2004
1VE6
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CRYSTAL STRUCTURE OF AN ACYLPEPTIDE HYDROLASE/ESTERASE FROM AEROPYRUM PERNIX K1
Descriptor:Acylamino-acid-releasing enzyme, B-OCTYLGLUCOSIDE, GLYCEROL
Authors:Bartlam, M., Wang, G., Gao, R., Yang, H., Zhao, X., Xie, G., Cao, S., Feng, Y., Rao, Z.
Deposit date:2004-03-27
Release date:2004-11-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of an acylpeptide hydrolase/esterase from Aeropyrum pernix K1
STRUCTURE, 12, 2004
2FBW
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AVIAN RESPIRATORY COMPLEX II WITH CARBOXIN BOUND
Descriptor:Succinate dehydrogenase flavoprotein subunit, succinate dehydrogenase Ip subunit, Succinate dehydrogenase cytochrome B, ...
Authors:Huang, L.S., Sun, G., Cobessi, D., Wang, A.C., Shen, J.T., Tung, E.Y., Anderson, V.E., Berry, E.A.
Deposit date:2005-12-10
Release date:2005-12-20
Last modified:2014-10-29
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:3-nitropropionic acid is a suicide inhibitor of mitochondrial respiration that, upon oxidation by complex II, forms a covalent adduct with a catalytic base arginine in the active site of the enzyme.
J.Biol.Chem., 281, 2006
2G9T
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CRYSTAL STRUCTURE OF THE SARS CORONAVIRUS NSP10 AT 2.1A
Descriptor:orf1a polyprotein, ZINC ION
Authors:Su, D., Lou, Z., Yang, H., Sun, F., Rao, Z.
Deposit date:2006-03-07
Release date:2006-08-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Dodecamer Structure of Severe Acute Respiratory Syndrome Coronavirus Nonstructural Protein nsp10
J.Virol., 80, 2006
3EWQ
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HCOV-229E NSP3 ADRP DOMAIN
Descriptor:Non-structural protein 3
Authors:Xu, Y., Cong, L., Chen, C., Wei, L., Zhao, Q., Xu, X., Ma, Y., Bartlam, M., Rao, Z.
Deposit date:2008-10-16
Release date:2009-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structures of two coronavirus ADP-ribose-1''-monophosphatases and their complexes with ADP-Ribose: a systematic structural analysis of the viral ADRP domain.
J.Virol., 83, 2009
6MYP
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AVIAN MITOCHONDRIAL COMPLEX II WITH TTFA (THENOYLTRIFLUOROACETONE) BOUND
Descriptor:Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial, Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, ...
Authors:Berry, E.A., Huang, L.-S.
Deposit date:2018-11-02
Release date:2019-11-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystallographic studies of the binding of ligands to the Ubiquinone-binding site of Mitochondrial Respiratory Complex II
To be published