Author results

1G55
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STRUCTURE OF HUMAN DNMT2, AN ENIGMATIC DNA METHYLTRANSFERASE HOMOLOGUE
Descriptor:DNA CYTOSINE METHYLTRANSFERASE DNMT2, SULFATE ION, S-ADENOSYL-L-HOMOCYSTEINE, ...
Authors:Dong, A., Yoder, J.A., Zhang, X., Zhou, L., Bestor, T.H., Cheng, X.
Deposit date:2000-10-30
Release date:2001-01-17
Last modified:2018-06-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of human DNMT2, an enigmatic DNA methyltransferase homolog that displays denaturant-resistant binding to DNA.
Nucleic Acids Res., 29, 2001
1Q0S
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BINARY STRUCTURE OF T4DAM WITH ADOHCY
Descriptor:DNA adenine methylase, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Yang, Z., Horton, J.R., Zhou, L., Zhang, X.J., Dong, A., Zhang, X., Schlagman, S.L., Kossykh, V., Hattman, S., Cheng, X.
Deposit date:2003-07-17
Release date:2003-09-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of the bacteriophage T4 DNA adenine methyltransferase
Nat.Struct.Biol., 10, 2003
1Q0T
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TERNARY STRUCTURE OF T4DAM WITH ADOHCY AND DNA
Descriptor:5'-D(*AP*CP*AP*GP*GP*AP*TP*CP*CP*TP*GP*T)-3', DNA adenine methylase, IODIDE ION, ...
Authors:Yang, Z., Horton, J.R., Zhou, L., Zhang, X.J., Dong, A., Zhang, X., Schlagman, S.L., Kossykh, V., Hattman, S., Cheng, X.
Deposit date:2003-07-17
Release date:2003-09-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure of the bacteriophage T4 DNA adenine methyltransferase
Nat.Struct.Biol., 10, 2003
1SVU
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STRUCTURE OF THE Q237W MUTANT OF HHAI DNA METHYLTRANSFERASE: AN INSIGHT INTO PROTEIN-PROTEIN INTERACTIONS
Descriptor:Modification methylase HhaI, SULFATE ION, S-ADENOSYL-L-HOMOCYSTEINE, ...
Authors:Dong, A., Zhou, L., Zhang, X., Stickel, S., Roberts, R.J., Cheng, X.
Deposit date:2004-03-30
Release date:2004-06-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.66 Å)
Cite:Structure of the Q237W mutant of HhaI DNA methyltransferase: an insight into protein-protein interactions
Biol.Chem., 385, 2004
1VS1
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CRYSTAL STRUCTURE OF 3-DEOXY-D-ARABINO-HEPTULOSONATE-7-PHOSPHATE SYNTHASE (DAHP SYNTHASE) FROM AEROPYRUM PERNIX IN COMPLEX WITH MN2+ AND PEP
Descriptor:3-deoxy-7-phosphoheptulonate synthase, MANGANESE (II) ION, PHOSPHOENOLPYRUVATE
Authors:Shumilin, I.A., Zhou, L., Wu, J., Woodard, R.W., Bauerle, R., Kretsinger, R.H.
Deposit date:2006-03-09
Release date:2006-05-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (DAHP synthase) from Aeropyrum pernix in complex with Mn2+ and PEP
TO BE PUBLISHED
2BW3
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THREE-DIMENSIONAL STRUCTURE OF THE HERMES DNA TRANSPOSASE
Descriptor:TRANSPOSASE
Authors:Hickman, A.B., Perez, Z.N., Zhou, L., Musingarimi, P., Ghirlando, R., Hinshaw, J.E., Craig, N.L., Dyda, F.
Deposit date:2005-07-11
Release date:2005-07-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Molecular Architecture of a Eukaryotic DNA Transposase
Nat.Struct.Mol.Biol., 12, 2005
3I9Z
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CRYSTAL STRUCTURE OF A METALLOCHAPERONE WITH A TRINUCLEAR CU(I) CLUSTER
Descriptor:Copper chaperone copZ, COPPER (I) ION
Authors:Hearnshaw, S.J., Zhou, L., Le Brun, N.E., Hemmings, A.M.
Deposit date:2009-07-13
Release date:2009-11-17
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Mechanistic insights into Cu(I) cluster transfer between the chaperone CopZ and its cognate Cu(I)-transporting P-type ATPase, CopA.
Biochem.J., 424, 2009
3L1L
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STRUCTURE OF ARG-BOUND ESCHERICHIA COLI ADIC
Descriptor:Arginine/agmatine antiporter, ARGININE, B-NONYLGLUCOSIDE
Authors:Gao, X., Zhou, L., Shi, Y.
Deposit date:2009-12-13
Release date:2010-02-02
Last modified:2014-02-12
Method:X-RAY DIFFRACTION (3.002 Å)
Cite:Mechanism of substrate recognition and transport by an amino acid antiporter
Nature, 463, 2010
3OTF
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STRUCTURAL BASIS FOR THE CAMP-DEPENDENT GATING IN HUMAN HCN4 CHANNEL
Descriptor:Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE
Authors:Xu, X., Vysotskaya, Z.V., Liu, Q., Zhou, L.
Deposit date:2010-09-11
Release date:2010-10-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis for the cAMP-dependent gating in the human HCN4 channel.
J.Biol.Chem., 285, 2010
4HBN
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CRYSTAL STRUCTURE OF THE HUMAN HCN4 CHANNEL C-TERMINUS CARRYING THE S672R MUTATION
Descriptor:Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, PHOSPHATE ION
Authors:Xu, X., Marni, F., Wu, X., Su, Z., Musayev, F., Shrestha, S., Xie, C., Gao, W., Liu, Q., Zhou, L.
Deposit date:2012-09-28
Release date:2013-01-16
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Local and Global Interpretations of a Disease-Causing Mutation near the Ligand Entry Path in Hyperpolarization-Activated cAMP-Gated Channel.
Structure, 20, 2012
4JN4
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ALLOSTERIC OPENING OF THE POLYPEPTIDE-BINDING SITE WHEN AN HSP70 BINDS ATP
Descriptor:Chaperone protein DnaK, MAGNESIUM ION, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Qi, R., Sarbeng, E.B., Liu, Q., Le, K.Q., Xu, X., Xu, H., Yang, J., Wong, J.L., Vorvis, C., Hendrickson, W.A., Zhou, L., Liu, Q.
Deposit date:2013-03-14
Release date:2013-05-29
Last modified:2013-08-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Allosteric opening of the polypeptide-binding site when an Hsp70 binds ATP.
Nat.Struct.Mol.Biol., 20, 2013
4JNE
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ALLOSTERIC OPENING OF THE POLYPEPTIDE-BINDING SITE WHEN AN HSP70 BINDS ATP
Descriptor:Hsp70 CHAPERONE DnaK, MAGNESIUM ION, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Qi, R., Sarbeng, E.B., Liu, Q., Le, K.Q., Xu, X., Xu, H., Yang, J., Wong, J.L., Vorvis, C., Hendrickson, W.A., Zhou, L., Liu, Q.
Deposit date:2013-03-15
Release date:2013-05-29
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Allosteric opening of the polypeptide-binding site when an Hsp70 binds ATP.
Nat.Struct.Mol.Biol., 20, 2013
4JNF
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ALLOSTERIC OPENING OF THE POLYPEPTIDE-BINDING SITE WHEN AN HSP70 BINDS ATP
Descriptor:Hsp70 CHAPERONE DnaK
Authors:Qi, R., Sarbeng, E.B., Liu, Q., Le, K.Q., Xu, X., Xu, H., Yang, J., Wong, J.L., Vorvis, C., Hendrickson, W.A., Zhou, L., Liu, Q.
Deposit date:2013-03-15
Release date:2013-05-29
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.621 Å)
Cite:Allosteric opening of the polypeptide-binding site when an Hsp70 binds ATP.
Nat.Struct.Mol.Biol., 20, 2013
5E84
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ATP-BOUND STATE OF BIP
Descriptor:78 kDa glucose-regulated protein, ADENOSINE-5'-TRIPHOSPHATE, ZINC ION, ...
Authors:Liu, Q., Yang, J., Nune, M., Zong, Y., Zhou, L.
Deposit date:2015-10-13
Release date:2016-01-27
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.99 Å)
Cite:Close and Allosteric Opening of the Polypeptide-Binding Site in a Human Hsp70 Chaperone BiP.
Structure, 23, 2015
5E85
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ISOLATED SBD OF BIP
Descriptor:78 kDa glucose-regulated protein, SULFATE ION
Authors:Liu, Q., Yang, J., Nune, M., Zong, Y., Zhou, L.
Deposit date:2015-10-13
Release date:2015-12-30
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.57 Å)
Cite:Close and Allosteric Opening of the Polypeptide-Binding Site in a Human Hsp70 Chaperone BiP.
Structure, 23, 2015
5E86
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ISOLATED SBD OF BIP WITH LOOP34 MODIFICATION
Descriptor:78 kDa glucose-regulated protein
Authors:Liu, Q., Yang, J., Nune, M., Zong, Y., Zhou, L.
Deposit date:2015-10-13
Release date:2015-12-30
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.681 Å)
Cite:Close and Allosteric Opening of the Polypeptide-Binding Site in a Human Hsp70 Chaperone BiP.
Structure, 23, 2015
5EAZ
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CRYSTAL FORM I OF YFIB BELONGING TO SPACE GROUPS P21
Descriptor:YfiB, SULFATE ION
Authors:Xu, M., Yang, X., Yang, X.-A., Zhou, L., Liu, T.-Z., Fan, Z., Jiang, T.
Deposit date:2015-10-17
Release date:2016-05-18
Last modified:2016-06-15
Method:X-RAY DIFFRACTION (2.151 Å)
Cite:Structural insights into the regulatory mechanism of the Pseudomonas aeruginosa YfiBNR system
Protein Cell, 7, 2016
5EB0
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CRYSTAL FORM II OF YFIB BELONGING TO P41
Descriptor:YfiB, SULFATE ION
Authors:Xu, M., Yang, X., Yang, X.-A., Zhou, L., Liu, T.-Z., Fan, Z., Jiang, T.
Deposit date:2015-10-17
Release date:2016-05-18
Last modified:2016-06-15
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural insights into the regulatory mechanism of the Pseudomonas aeruginosa YfiBNR system
Protein Cell, 7, 2016
5EB1
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THE YFIB-YFIR COMPLEX
Descriptor:YfiR, YfiB, SULFATE ION
Authors:Xu, M., Yang, X., Yang, X.-A., Zhou, L., Liu, T.-Z., Fan, Z., Jiang, T.
Deposit date:2015-10-17
Release date:2016-05-18
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural insights into the regulatory mechanism of the Pseudomonas aeruginosa YfiBNR system
Protein Cell, 7, 2016
5EB2
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TRP-BOUND YFIR
Descriptor:YfiR, TRYPTOPHAN, SULFATE ION
Authors:Xu, M., Yang, X., Yang, X.-A., Zhou, L., Liu, T.-Z., Fan, Z., Jiang, T.
Deposit date:2015-10-17
Release date:2016-05-18
Last modified:2016-06-15
Method:X-RAY DIFFRACTION (2.709 Å)
Cite:Structural insights into the regulatory mechanism of the Pseudomonas aeruginosa YfiBNR system
Protein Cell, 7, 2016
5EB3
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VB6-BOUND PROTEIN
Descriptor:YfiR, SULFATE ION, 4,5-bis(hydroxymethyl)-2-methyl-pyridin-3-ol
Authors:Xu, M., Yang, X., Yang, X.-A., Zhou, L., Liu, T.-Z., Fan, Z., Jiang, T.
Deposit date:2015-10-17
Release date:2016-05-18
Last modified:2016-06-15
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural insights into the regulatory mechanism of the Pseudomonas aeruginosa YfiBNR system
Protein Cell, 7, 2016
5W96
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SOLUTION STRUCTURE OF PHAGE DERIVED PEPTIDE INHIBITOR OF FRIZZLED 7 RECEPTOR
Descriptor:Fz7 binding peptide
Authors:Nile, A.H., de Sousa e Melo, F., Mukund, S., Piskol, R., Hansen, S., Zhou, L., Zhang, Y., Fu, Y., Gogol, E.B., Komuves, L.G., Modrusan, Z., Angers, S., Franke, Y., Koth, C., Fairbrother, W.J., Wang, W., de Sauvage, F.J., Hannoush, R.N.
Deposit date:2017-06-22
Release date:2018-04-18
Last modified:2018-05-30
Method:SOLUTION NMR
Cite:A selective peptide inhibitor of Frizzled 7 receptors disrupts intestinal stem cells.
Nat. Chem. Biol., 14, 2018
5Y2Q
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X-RAY STRUCTURE OF ACETYLCHOLINE BINDING PROTEIN (ACHBP) COMPLEXED WITH A SMALL MOLECULE
Descriptor:Acetylcholine-binding protein, 3-[[4-[(3,4-dichlorophenyl)methyl]piperidin-4-yl]methoxy]pyridine
Authors:Jiang, L.L., Zhou, L.
Deposit date:2017-07-26
Release date:2018-08-08
Method:X-RAY DIFFRACTION (2.363 Å)
Cite:X-ray structure of acetylcholine binding protein (AChBP) complexed with a small molecule
To Be Published
5Y35
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PHOSPHOGLYCERATE MUTASE 1 COMPLEXED WITH A SMALL MOLECULE INHIBITOR KH1
Descriptor:Phosphoglycerate mutase 1, CHLORIDE ION, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ...
Authors:Jiang, L.L., Zhou, L.
Deposit date:2017-07-27
Release date:2018-08-08
Method:X-RAY DIFFRACTION (1.994 Å)
Cite:Phosphoglycerate mutase 1 complexed with a small molecule inhibitor KH1
To Be Published
5Y65
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PHOSPHOGLYCERATE MUTASE 1 COMPLEXED WITH A SMALL MOLECULE INHIBITOR KH2
Descriptor:Phosphoglycerate mutase 1, CHLORIDE ION, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ...
Authors:Jiang, L.L., Zhou, L.
Deposit date:2017-08-10
Release date:2018-12-05
Method:X-RAY DIFFRACTION (2.554 Å)
Cite:Phosphoglycerate mutase 1 complexed with a small molecule inhibitor KH2
To Be Published