Author results

6HCP
  • Download 6hcp
  • View 6hcp
Molmil generated image of 6hcp
CRYSTAL STRUCTURE OF BAUA, THE FERRIC PREACINETOBACTIN RECEPTOR FROM ACINETOBACTER BAUMANNII
Descriptor:BauA, 1,2-ETHANEDIOL, (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, ...
Authors:Moynie, L., Naismith, J.H.
Deposit date:2018-08-16
Release date:2018-10-10
Last modified:2019-01-16
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Preacinetobactin not acinetobactin is essential for iron uptake by the BauA transporter of the pathogenAcinetobacter baumannii.
Elife, 7, 2018
6I2J
  • Download 6i2j
  • View 6i2j
Molmil generated image of 6i2j
CRYSTAL STRUCTURE OF THE FERRIC ENTEROBACTIN RECEPTOR MUTANT (Q482A) FROM PSEUDOMONAS AERUGINOSA (PFEA) IN COMPLEX WITH ENTEROBACTIN
Descriptor:Ferric enterobactin receptor, FE (III) ION, N,N',N''-[(3S,7S,11S)-2,6,10-trioxo-1,5,9-trioxacyclododecane-3,7,11-triyl]tris(2,3-dihydroxybenzamide)
Authors:Moynie, L., Naismith, J.H.
Deposit date:2018-11-01
Release date:2019-01-16
Method:X-RAY DIFFRACTION (2.96 Å)
Cite:Crystal structure of the ferric enterobactin receptor (PfeA) mutant from Pseudomonas aeruginosa
To Be Published
6Q5E
  • Download 6q5e
  • View 6q5e
Molmil generated image of 6q5e
CRYSTAL STRUCTURE OF THE FERRIC ENTEROBACTIN RECEPTOR FROM PSEUDOMONAS AERUGINOSA (PFEA) IN COMPLEX WITH ENTEROBACTIN
Descriptor:Ferric enterobactin receptor, FE (III) ION, N,N',N''-[(3S,7S,11S)-2,6,10-trioxo-1,5,9-trioxacyclododecane-3,7,11-triyl]tris(2,3-dihydroxybenzamide), ...
Authors:Moynie, L., Naismith, J.H.
Deposit date:2018-12-07
Release date:2019-01-16
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of the ferric enterobactin receptor (PfeA) mutant from Pseudomonas aeruginosa
To Be Published
6R1F
  • Download 6r1f
  • View 6r1f
Molmil generated image of 6r1f
CRYSTAL STRUCTURE OF THE FERRIC ENTEROBACTIN RECEPTOR MUTANT R480A FROM PSEUDOMONAS AERUGINOSA (PFEA) IN COMPLEX WITH ENTEROBACTIN
Descriptor:Ferric enterobactin receptor, FE (III) ION, N,N',N''-[(3S,7S,11S)-2,6,10-trioxo-1,5,9-trioxacyclododecane-3,7,11-triyl]tris(2,3-dihydroxybenzamide)
Authors:Moynie, L., Naismith, J.H.
Deposit date:2019-03-14
Release date:2019-04-10
Last modified:2019-07-10
Method:X-RAY DIFFRACTION (3.11 Å)
Cite:Crystal structure of the ferric enterobactin receptor (PfeA) mutant from Pseudomonas aeruginosa
To Be Published
5NEC
  • Download 5nec
  • View 5nec
Molmil generated image of 5nec
CRYSTAL STRUCTURE OF THE SIDEROPHORE RECEPTOR PIUD FROM PSEUDOMONAS AERUGINOSA
Descriptor:TonB-dependent siderophore receptor, (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE
Authors:Moynie, L., Naismith, J.H.
Deposit date:2017-03-10
Release date:2018-02-07
Last modified:2018-08-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:TonB-Dependent Receptor Repertoire of Pseudomonas aeruginosa for Uptake of Siderophore-Drug Conjugates.
Antimicrob. Agents Chemother., 62, 2018
2XU8
  • Download 2xu8
  • View 2xu8
Molmil generated image of 2xu8
STRUCTURE OF PA1645
Descriptor:PA1645, SULFATE ION
Authors:Abdelli, W.B., Moynie, L., McMahon, S.A., Liu, H., Alphey, M.S., Naismith, J.H.
Deposit date:2010-10-15
Release date:2010-12-29
Last modified:2015-08-19
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:The Aeropath Project Targeting Pseudomonas Aeruginosa: Crystallographic Studies for Assessment of Potential Targets in Early-Stage Drug Discovery
Acta Crystallogr.,Sect.F, 69, 2013
4AVF
  • Download 4avf
  • View 4avf
Molmil generated image of 4avf
CRYSTAL STRUCTURE OF PSEUDOMONAS AERUGINOSA INOSINE 5'-MONOPHOSPHATE DEHYDROGENASE
Descriptor:INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE
Authors:McMahon, S.A., Moynie, L., Liu, H., Duthie, F., Naismith, J.H.
Deposit date:2012-05-25
Release date:2013-01-09
Last modified:2013-01-23
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:The Aeropath Project Targeting Pseudomonas Aeruginosa: Crystallographic Studies for Assessment of Potential Targets in Early-Stage Drug Discovery
Acta Crystallogr.,Sect.F, 69, 2013
4AVR
  • Download 4avr
  • View 4avr
Molmil generated image of 4avr
CRYSTAL STRUCTURE OF THE HYPOTHETICAL PROTEIN PA4485 FROM PSEUDOMONAS AERUGINOSA
Descriptor:PA4485
Authors:McMahon, S.A., Moynie, L., Liu, H., Duthie, F., Alphey, M.S., Naismith, J.H.
Deposit date:2012-05-29
Release date:2013-01-09
Last modified:2013-01-23
Method:X-RAY DIFFRACTION (1.08 Å)
Cite:The Aeropath Project Targeting Pseudomonas Aeruginosa: Crystallographic Studies for Assessment of Potential Targets in Early-Stage Drug Discovery.
Acta Crystallogr.,Sect.F, 69, 2013
5FLG
  • Download 5flg
  • View 5flg
Molmil generated image of 5flg
CRYSTAL STRUCTURE OF THE 6-CARBOXYHEXANOATE-COA LIGASE (BIOW)FROM BACILLUS SUBTILIS IN COMPLEX WITH AMPPNP
Descriptor:6-CARBOXYHEXANOATE--COA LIGASE, PIMELIC ACID, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Moynie, L., Wang, M., Campopiano, D.J., Naismith, J.H.
Deposit date:2015-10-26
Release date:2016-11-16
Last modified:2017-05-24
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Using the pimeloyl-CoA synthetase adenylation fold to synthesize fatty acid thioesters.
Nat. Chem. Biol., 13, 2017
5FLL
  • Download 5fll
  • View 5fll
Molmil generated image of 5fll
CRYSTAL STRUCTURE OF THE 6-CARBOXYHEXANOATE-COA LIGASE (BIOW) FROM BACILLUS SUBTILIS IN COMPLEX WITH A PIMELOYL-ADENYLATE
Descriptor:6-CARBOXYHEXANOATE-COA LIGASE, PIMELOYL-AMP, PYROPHOSPHATE, ...
Authors:Moynie, L., Wang, M., Campopiano, D.J., Naismith, J.H.
Deposit date:2015-10-26
Release date:2016-11-16
Last modified:2018-06-13
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Using the pimeloyl-CoA synthetase adenylation fold to synthesize fatty acid thioesters.
Nat. Chem. Biol., 13, 2017
5FM0
  • Download 5fm0
  • View 5fm0
Molmil generated image of 5fm0
CRYSTAL STRUCTURE OF THE 6-CARBOXYHEXANOATE-COA LIGASE (BIOW)FROM BACILLUS SUBTILIS (PTCL4 DERIVATIVE)
Descriptor:6-CARBOXYHEXANOATE--COA LIGASE, PIMELOYL-AMP, PYROPHOSPHATE, ...
Authors:Moynie, L., Wang, M., Campopiano, D.J., Naismith, J.H.
Deposit date:2015-10-29
Release date:2016-11-16
Last modified:2017-05-24
Method:X-RAY DIFFRACTION (2.44 Å)
Cite:Using the pimeloyl-CoA synthetase adenylation fold to synthesize fatty acid thioesters.
Nat. Chem. Biol., 13, 2017
5G1F
  • Download 5g1f
  • View 5g1f
Molmil generated image of 5g1f
CRYSTAL STRUCTURE OF THE 6-CARBOXYHEXANOATE-COA LIGASE (BIOW)FROM BACILLUS SUBTILIS IN COMPLEX WITH COENZYME A
Descriptor:6-CARBOXYHEXANOATE-COA LIGASE, PIMELIC ACID, NONAETHYLENE GLYCOL, ...
Authors:Moynie, L., Wang, M., Campopiano, D.J., Naismith, J.H.
Deposit date:2016-03-25
Release date:2017-03-08
Last modified:2017-06-21
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:The Structure of the 6-Carboxyhexanoate-Coa Ligase from Bacillus Subtilis
To be Published
6GI0
  • Download 6gi0
  • View 6gi0
Molmil generated image of 6gi0
CRYSTAL STRUCTURE OF THE FERRIC ENTEROBACTIN ESTERASE (PFEE) FROM PSEUDOMONAS AERUGINOSA
Descriptor:Ferric enterobactin esterase, NITRATE ION
Authors:Moynie, L., Naismith, J.H.
Deposit date:2018-05-09
Release date:2018-06-20
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:A Key Role for the Periplasmic PfeE Esterase in Iron Acquisition via the Siderophore Enterobactin in Pseudomonas aeruginosa.
ACS Chem. Biol., 13, 2018
6GI1
  • Download 6gi1
  • View 6gi1
Molmil generated image of 6gi1
CRYSTAL STRUCTURE OF THE FERRIC ENTEROBACTIN ESTERASE (PFEE) MUTANT(S157A) FROM PSEUDOMONAS AERUGINOSA IN PRESENCE OF ENTEROBACTIN
Descriptor:Ferric enterobactin esterase, FE (III) ION, 2-(2,3-DIHYDROXY-BENZOYLAMINO)-3-HYDROXY-PROPIONIC ACID, ...
Authors:Moynie, L., Naismith, J.H.
Deposit date:2018-05-09
Release date:2018-06-20
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:A Key Role for the Periplasmic PfeE Esterase in Iron Acquisition via the Siderophore Enterobactin in Pseudomonas aeruginosa.
ACS Chem. Biol., 13, 2018
6GI2
  • Download 6gi2
  • View 6gi2
Molmil generated image of 6gi2
CRYSTAL STRUCTURE OF THE FERRIC ENTEROBACTIN ESTERASE (PFEE) MUTANT(S157A) FROM PSEUDOMONAS AERUGINOSA IN COMPLEX WITH TRIS-CATECHOL VECTOR
Descriptor:Ferric enterobactin esterase, FE (III) ION, ~{N}-[2-[[(2~{S})-2-[[2,3-bis(oxidanyl)phenyl]carbonylamino]-3-[[(2~{S})-2-[[2,3-bis(oxidanyl)phenyl]carbonylamino]-3-oxidanylidene-3-(prop-2-ynylamino)propyl]amino]-3-oxidanylidene-propyl]amino]-2-oxidanylidene-ethyl]-2,3-bis(oxidanyl)benzamide, ...
Authors:Moynie, L., Naismith, J.H.
Deposit date:2018-05-09
Release date:2018-06-20
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:A Key Role for the Periplasmic PfeE Esterase in Iron Acquisition via the Siderophore Enterobactin in Pseudomonas aeruginosa.
ACS Chem. Biol., 13, 2018
6GI5
  • Download 6gi5
  • View 6gi5
Molmil generated image of 6gi5
CRYSTAL STRUCTURE OF THE FERRIC ENTEROBACTIN ESTERASE (PFEE) FROM PSEUDOMONAS AERUGINOSA IN COMPLEX WITH THE TRIS-CATECHOL VECTOR
Descriptor:Ferric enterobactin esterase, FE (III) ION, ~{N}-[2-[[(2~{S})-2-[[2,3-bis(oxidanyl)phenyl]carbonylamino]-3-[[(2~{S})-2-[[2,3-bis(oxidanyl)phenyl]carbonylamino]-3-oxidanylidene-3-(prop-2-ynylamino)propyl]amino]-3-oxidanylidene-propyl]amino]-2-oxidanylidene-ethyl]-2,3-bis(oxidanyl)benzamide
Authors:Moynie, L., Naismith, J.H.
Deposit date:2018-05-09
Release date:2018-06-20
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (3.11 Å)
Cite:A Key Role for the Periplasmic PfeE Esterase in Iron Acquisition via the Siderophore Enterobactin in Pseudomonas aeruginosa.
ACS Chem. Biol., 13, 2018
3ZTQ
  • Download 3ztq
  • View 3ztq
Molmil generated image of 3ztq
HEXAGONAL CRYSTAL FORM P61 OF THE AQUIFEX AEOLICUS NUCLEOSIDE DIPHOSPHATE KINASE
Descriptor:NUCLEOSIDE DIPHOSPHATE KINASE
Authors:Boissier, F., Georgescauld, F., Moynie, L., Dupuy, J.-W., Sarger, C., Podar, M., Lascu, I., Giraud, M.-F., Dautant, A.
Deposit date:2011-07-12
Release date:2012-02-29
Last modified:2012-05-23
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:An Inter-Subunit Disulphide Bridge Stabilizes the Tetrameric Nucleoside Diphosphate Kinase of Aquifex Aeolicus
Proteins, 80, 2012
3ZTR
  • Download 3ztr
  • View 3ztr
Molmil generated image of 3ztr
HEXAGONAL FORM P6122 OF THE AQUIFEX AEOLICUS NUCLEOSIDE DIPHOSPHATE KINASE (FIRST STAGE OF RADIATION DAMAGE)
Descriptor:NUCLEOSIDE DIPHOSPHATE KINASE
Authors:Boissier, F., Georgescauld, F., Moynie, L., Dupuy, J.-W., Sarger, C., Podar, M., Lascu, I., Giraud, M.-F., Dautant, A.
Deposit date:2011-07-12
Release date:2012-03-14
Last modified:2012-05-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:An Inter-Subunit Disulphide Bridge Stabilizes the Tetrameric Nucleoside Diphosphate Kinase of Aquifex Aeolicus
Proteins, 80, 2012
3ZTS
  • Download 3zts
  • View 3zts
Molmil generated image of 3zts
HEXAGONAL FORM P6122 OF THE AQUIFEX AEOLICUS NUCLEOSIDE DIPHOSPHATE KINASE (FINAL STAGE OF RADIATION DAMAGE)
Descriptor:NUCLEOSIDE DIPHOSPHATE KINASE
Authors:Boissier, F., Georgescauld, F., Moynie, L., Dupuy, J.-W., Sarger, C., Podar, M., Lascu, I., Giraud, M.-F., Dautant, A.
Deposit date:2011-07-12
Release date:2012-03-14
Last modified:2012-05-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:An Inter-Subunit Disulphide Bridge Stabilizes the Tetrameric Nucleoside Diphosphate Kinase of Aquifex Aeolicus
Proteins, 80, 2012
4ANE
  • Download 4ane
  • View 4ane
Molmil generated image of 4ane
R80N MUTANT OF NUCLEOSIDE DIPHOSPHATE KINASE FROM MYCOBACTERIUM TUBERCULOSIS
Descriptor:NUCLEOSIDE DIPHOSPHATE KINASE, CITRIC ACID
Authors:Georgescauld, F., Moynie, L., Habersetzer, J., Lascu, I., Dautant, A.
Deposit date:2012-03-16
Release date:2013-03-13
Last modified:2014-01-22
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of Mycobacterium Tuberculosis Nucleoside Diphosphate Kinase R80N Mutant in Complex with Citrate
Acta Crystallogr.,Sect.D, 70, 2014
3ZTO
  • Download 3zto
  • View 3zto
Molmil generated image of 3zto
ORTHORHOMBIC CRYSTAL FORM C222 OF THE AQUIFEX AEOLICUS NUCLEOSIDE DIPHOSPHATE KINASE
Descriptor:NUCLEOSIDE DIPHOSPHATE KINASE, SULFATE ION
Authors:Boissier, F., Georgescauld, F., Moynie, L., Dupuy, J.-W., Sarger, C., Podar, M., Lascu, I., Giraud, M.-F., Dautant, A.
Deposit date:2011-07-12
Release date:2012-03-14
Last modified:2012-05-23
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:An Intersubunit Disulfide Bridge Stabilizes the Tetrameric Nucleoside Diphosphate Kinase of Aquifex Aeolicus.
Proteins, 80, 2012
3ZTP
  • Download 3ztp
  • View 3ztp
Molmil generated image of 3ztp
ORTHORHOMBIC CRYSTAL FORM P21212 OF THE AQUIFEX AEOLICUS NUCLEOSIDE DIPHOSPHATE KINASE
Descriptor:NUCLEOSIDE DIPHOSPHATE KINASE, GLYCEROL, SULFATE ION
Authors:Boissier, F., Georgescauld, F., Moynie, L., Dupuy, J.-W., Sarger, C., Podar, M., Lascu, I., Giraud, M.-F., Dautant, A.
Deposit date:2011-07-12
Release date:2012-03-14
Last modified:2012-05-23
Method:X-RAY DIFFRACTION (1.37 Å)
Cite:An Intersubunit Disulfide Bridge Stabilizes the Tetrameric Nucleoside Diphosphate Kinase of Aquifex Aeolicus.
Proteins, 80, 2012
4ANC
  • Download 4anc
  • View 4anc
Molmil generated image of 4anc
CRYSTAL FORM I OF THE D93N MUTANT OF NUCLEOSIDE DIPHOSPHATE KINASE FROM MYCOBACTERIUM TUBERCULOSIS
Descriptor:NUCLEOSIDE DIPHOSPHATE KINASE
Authors:Georgescauld, F., Moynie, L., Habersetzer, J., Lascu, I., Dautant, A.
Deposit date:2012-03-16
Release date:2013-03-13
Last modified:2013-04-03
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Intersubunit Ionic Interactions Stabilize the Nucleoside Diphosphate Kinase of Mycobacterium Tuberculosis.
Plos One, 8, 2013
4AND
  • Download 4and
  • View 4and
Molmil generated image of 4and
CRYSTAL FORM II OF THE D93N MUTANT OF NUCLEOSIDE DIPHOSPHATE KINASE FROM MYCOBACTERIUM TUBERCULOSIS
Descriptor:NUCLEOSIDE DIPHOSPHATE KINASE
Authors:Georgescauld, F., Moynie, L., Habersetzer, J., Lascu, I., Dautant, A.
Deposit date:2012-03-16
Release date:2013-03-13
Last modified:2013-04-03
Method:X-RAY DIFFRACTION (2.808 Å)
Cite:Intersubunit Ionic Interactions Stabilize the Nucleoside Diphosphate Kinase of Mycobacterium Tuberculosis.
Plos One, 8, 2013
5LDT
  • Download 5ldt
  • View 5ldt
Molmil generated image of 5ldt
CRYSTAL STRUCTURES OF MOMP FROM CAMPYLOBACTER JEJUNI
Descriptor:MOMP porin, CALCIUM ION, (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE
Authors:Ferrara, L.G.M., Wallat, G.D., Moynie, L., Naismith, J.H.
Deposit date:2016-06-27
Release date:2016-10-26
Last modified:2016-11-09
Method:X-RAY DIFFRACTION (2.88 Å)
Cite:MOMP from Campylobacter jejuni Is a Trimer of 18-Stranded beta-Barrel Monomers with a Ca(2+) Ion Bound at the Constriction Zone.
J.Mol.Biol., 428, 2016