1OYE
| Structural Basis of Multiple Binding Capacity of the AcrB multidrug Efflux Pump | Descriptor: | 1-CYCLOPROPYL-6-FLUORO-4-OXO-7-PIPERAZIN-1-YL-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID, Acriflavine resistance protein B | Authors: | Yu, E.W, McDermott, G, Zgurskaya, H.I, Nikaido, H, Koshland Jr, D.E. | Deposit date: | 2003-04-03 | Release date: | 2003-05-13 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3.48 Å) | Cite: | Structural basis of multiple drug-binding capacity of the AcrB multidrug efflux pump. Science, 300, 2003
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1OY9
| Structural Basis of Multiple Drug Binding Capacity of the AcrB Multidrug Efflux Pump | Descriptor: | Acriflavine resistance protein B, ETHIDIUM | Authors: | Yu, E.W, McDermott, G, Zgurskaya, H.I, Nikaido, H, Koshland Jr, D.E. | Deposit date: | 2003-04-03 | Release date: | 2003-05-13 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3.8 Å) | Cite: | Structural basis of multiple drug-binding capacity of the AcrB multidrug efflux pump. Science, 300, 2003
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1OYD
| Structural Basis of Multiple Binding Capacity of the AcrB multidrug Efflux Pump | Descriptor: | Acriflavine resistance protein B, DEQUALINIUM | Authors: | Yu, E.W, MeDermott, G, Zgurskaya, H.I, Nikaido, H, Koshland Jr, D.E. | Deposit date: | 2003-04-03 | Release date: | 2003-05-13 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3.8 Å) | Cite: | Structural basis of multiple drug-binding capacity of the AcrB multidrug efflux pump. Science, 300, 2003
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1OY6
| Structural Basis of the Multiple Binding Capacity of the AcrB Multidrug Efflux Pump | Descriptor: | Acriflavine resistance protein B | Authors: | Yu, E.W, McDermott, G, Zgurskaya, H.I, Nikaido, H, Koshland Jr, D.E. | Deposit date: | 2003-04-03 | Release date: | 2003-05-13 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3.68 Å) | Cite: | Structural basis of multiple drug-binding capacity of the AcrB multidrug efflux pump. Science, 300, 2003
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1OY8
| Structural Basis of Multiple Drug Binding Capacity of the AcrB Multidrug Efflux Pump | Descriptor: | Acriflavine resistance protein B, RHODAMINE 6G | Authors: | Yu, E.W, McDermott, G, Zgurskaya, H.I, Nikaido, H, Koshland Jr, D.E. | Deposit date: | 2003-04-03 | Release date: | 2003-05-13 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3.63 Å) | Cite: | Structural basis of multiple drug-binding capacity of the AcrB multidrug efflux pump. Science, 300, 2003
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1T9U
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1T9V
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1T9X
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1T9W
| Structural Basis of Multidrug Transport by the AcrB Multidrug Efflux Pump | Descriptor: | 6-[[(2-ETHOXY-1-NAPHTHALENYL)CARBONYL]AMINO]-3,3-DIMETHYL-7-OXO-4-THIA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLATE, Acriflavine resistance protein B | Authors: | Yu, E.W, McDermott, G, Nikaido, H. | Deposit date: | 2004-05-18 | Release date: | 2005-10-04 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3.23 Å) | Cite: | A Periplasmic Drug-Binding Site of the AcrB Multidrug Efflux Pump: a Crystallographic and Site-Directed Mutagenesis Study J.Bacteriol., 187, 2005
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1T9T
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1T9Y
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7MXY
| Cryo-EM structure of PfFNT-inhibitor complex | Descriptor: | (Z)-4,4,5,5,5-pentakis(fluoranyl)-1-(4-methoxy-2-oxidanyl-phenyl)-3-oxidanyl-pent-2-en-1-one, Formate-nitrite transporter | Authors: | Yu, E.W, Su, C, Lyu, M. | Deposit date: | 2021-05-19 | Release date: | 2021-12-08 | Method: | ELECTRON MICROSCOPY (2.18 Å) | Cite: | Structural basis of transport and inhibition of the Plasmodium falciparum transporter PfFNT EMBO Rep, 22, 2021
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1JMW
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6E5F
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6E5D
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7RYF
| A. baumannii Ribosome-TP-6076 complex: P-site tRNA 70S | Descriptor: | (4S,4aS,5aR,12aS)-4-(diethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-8-[(2S)-pyrrolidin-2-yl]-7-(trifluoromethyl)-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide, 16S Ribosomal RNA, 23S ribosomal RNA, ... | Authors: | Morgan, C.E, Yu, E.W. | Deposit date: | 2021-08-25 | Release date: | 2022-02-02 | Last modified: | 2022-12-07 | Method: | ELECTRON MICROSCOPY (2.65 Å) | Cite: | An Analysis of the Novel Fluorocycline TP-6076 Bound to Both the Ribosome and Multidrug Efflux Pump AdeJ from Acinetobacter baumannii. Mbio, 13, 2022
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7RYH
| A. baumannii Ribosome-TP-6076 complex: Empty 70S | Descriptor: | (4S,4aS,5aR,12aS)-4-(diethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-8-[(2S)-pyrrolidin-2-yl]-7-(trifluoromethyl)-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide, 16S Ribosomal RNA, 23S ribosomal RNA, ... | Authors: | Morgan, C.E, Yu, E.W. | Deposit date: | 2021-08-25 | Release date: | 2022-02-02 | Last modified: | 2022-12-07 | Method: | ELECTRON MICROSCOPY (2.43 Å) | Cite: | An Analysis of the Novel Fluorocycline TP-6076 Bound to Both the Ribosome and Multidrug Efflux Pump AdeJ from Acinetobacter baumannii. Mbio, 13, 2022
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7RYG
| A. baumannii Ribosome-TP-6076 complex: E-site tRNA 70S | Descriptor: | (4S,4aS,5aR,12aS)-4-(diethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-8-[(2S)-pyrrolidin-2-yl]-7-(trifluoromethyl)-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide, 16S Ribosomal RNA, 23S ribosomal RNA, ... | Authors: | Morgan, C.E, Yu, E.W. | Deposit date: | 2021-08-25 | Release date: | 2022-02-02 | Last modified: | 2022-12-07 | Method: | ELECTRON MICROSCOPY (2.38 Å) | Cite: | An Analysis of the Novel Fluorocycline TP-6076 Bound to Both the Ribosome and Multidrug Efflux Pump AdeJ from Acinetobacter baumannii. Mbio, 13, 2022
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5KHS
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5KHN
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3T6N
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3T53
| Crystal structures of the extrusion state of the CusBA adaptor-transporter complex | Descriptor: | COPPER (II) ION, Cation efflux system protein CusA, Cation efflux system protein CusB | Authors: | Su, C.-C, Long, F, Yu, E.W. | Deposit date: | 2011-07-26 | Release date: | 2012-06-20 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.37 Å) | Cite: | Charged Amino Acids (R83, E567, D617, E625, R669, and K678) of CusA Are Required for Metal Ion Transport in the Cus Efflux System. J.Mol.Biol., 422, 2012
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3T51
| Crystal structures of the pre-extrusion and extrusion states of the CusBA adaptor-transporter complex | Descriptor: | COPPER (II) ION, Cation efflux system protein CusA, Cation efflux system protein CusB | Authors: | Su, C.-C, Long, F, Yu, E.W. | Deposit date: | 2011-07-26 | Release date: | 2012-06-20 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.9 Å) | Cite: | Charged Amino Acids (R83, E567, D617, E625, R669, and K678) of CusA Are Required for Metal Ion Transport in the Cus Efflux System. J.Mol.Biol., 422, 2012
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3T56
| Crystal structure of the pre-extrusion state of the CusBA adaptor-transporter complex | Descriptor: | COPPER (II) ION, Cation efflux system protein CusA, Cation efflux system protein CusB | Authors: | Su, C.-C, Long, F, Yu, E.W. | Deposit date: | 2011-07-26 | Release date: | 2012-06-20 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.42 Å) | Cite: | Charged Amino Acids (R83, E567, D617, E625, R669, and K678) of CusA Are Required for Metal Ion Transport in the Cus Efflux System. J.Mol.Biol., 422, 2012
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3V78
| Crystal Structure of Transcriptional Regulator | Descriptor: | ETHIDIUM, PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY DEOR-FAMILY) | Authors: | Do, S.V, Bolla, J.R, Chen, X, Yu, E.W. | Deposit date: | 2011-12-20 | Release date: | 2012-12-26 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.299 Å) | Cite: | Structural and functional analysis of the transcriptional regulator Rv3066 of Mycobacterium tuberculosis. Nucleic Acids Res., 40, 2012
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