8WYD
 
 | | Cryo-EM structure of DSR2-DSAD1 complex | | Descriptor: | Bacillus phage SPbeta DSAD1 protein, SIR2 family protein | | Authors: | Zhang, J.T, Jia, N, Liu, X.Y. | | Deposit date: | 2023-10-30 | | Release date: | 2024-04-10 | | Last modified: | 2024-04-17 | | Method: | ELECTRON MICROSCOPY (2.56 Å) | | Cite: | Structural basis for phage-mediated activation and repression of bacterial DSR2 anti-phage defense system.
Nat Commun, 15, 2024
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8WYE
 | | Cryo-EM structure of DSR2-DSAD1 (partial) complex | | Descriptor: | Bacillus phage SPbeta DSAD1 protein, SIR2 family protein | | Authors: | Zhang, J.T, Jia, N, Liu, X.Y. | | Deposit date: | 2023-10-30 | | Release date: | 2024-04-10 | | Last modified: | 2024-04-17 | | Method: | ELECTRON MICROSCOPY (2.49 Å) | | Cite: | Structural basis for phage-mediated activation and repression of bacterial DSR2 anti-phage defense system.
Nat Commun, 15, 2024
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8WY9
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8WYA
 | | Cryo-EM structure of DSR2-tube complex | | Descriptor: | Bacillus phage SPbeta tube protein, SIR2 family protein | | Authors: | Zhang, J.T, Jia, N, Liu, X.Y. | | Deposit date: | 2023-10-30 | | Release date: | 2024-04-10 | | Last modified: | 2024-04-17 | | Method: | ELECTRON MICROSCOPY (3.62 Å) | | Cite: | Structural basis for phage-mediated activation and repression of bacterial DSR2 anti-phage defense system.
Nat Commun, 15, 2024
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8WYB
 | | Cryo-EM structure of DSR2 (H171A)-tube-NAD+ complex | | Descriptor: | Bacillus phage SPR Tube protein, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SIR2-like domain-containing protein | | Authors: | Zhang, J.T, Jia, N, Liu, X.Y. | | Deposit date: | 2023-10-30 | | Release date: | 2024-04-10 | | Last modified: | 2024-04-17 | | Method: | ELECTRON MICROSCOPY (3.37 Å) | | Cite: | Structural basis for phage-mediated activation and repression of bacterial DSR2 anti-phage defense system.
Nat Commun, 15, 2024
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8WY8
 | | Cryo-EM structure of DSR2 apo complex | | Descriptor: | SIR2 family protein | | Authors: | Zhang, J.T, Jia, N, Liu, X.Y. | | Deposit date: | 2023-10-30 | | Release date: | 2024-04-10 | | Last modified: | 2024-04-17 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Structural basis for phage-mediated activation and repression of bacterial DSR2 anti-phage defense system.
Nat Commun, 15, 2024
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8WYF
 | | Cryo-EM structure of DSR2-DSAD1-NAD+ (partial) complex | | Descriptor: | Bacillus phage SPbeta DSAD1 protein, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SIR2 family protein | | Authors: | Zhang, J.T, Jia, N, Liu, X.Y. | | Deposit date: | 2023-10-30 | | Release date: | 2024-04-10 | | Last modified: | 2024-04-17 | | Method: | ELECTRON MICROSCOPY (2.85 Å) | | Cite: | Structural basis for phage-mediated activation and repression of bacterial DSR2 anti-phage defense system.
Nat Commun, 15, 2024
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8WYC
 | | Cryo-EM structure of DSR2 (H171A)-tube-NAD+ (partial) complex | | Descriptor: | Bacillus phage SPR Tube protein, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SIR2-like domain-containing protein | | Authors: | Zhang, J.T, Jia, N, Liu, X.Y. | | Deposit date: | 2023-10-30 | | Release date: | 2024-04-10 | | Last modified: | 2024-04-17 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Structural basis for phage-mediated activation and repression of bacterial DSR2 anti-phage defense system.
Nat Commun, 15, 2024
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8K34
 | | Cryo-EM structure of SPARTA gRNA binary complex | | Descriptor: | MAGNESIUM ION, Piwi domain-containing protein, RNA (5'-R(P*AP*AP*AP*CP*GP*GP*CP*UP*CP*UP*AP*AP*UP*CP*UP*AP*UP*UP*AP*GP*U)-3'), ... | | Authors: | Zhang, J.T, Jia, N. | | Deposit date: | 2023-07-14 | | Release date: | 2024-01-17 | | Last modified: | 2024-04-10 | | Method: | ELECTRON MICROSCOPY (2.81 Å) | | Cite: | Target ssDNA activates the NADase activity of prokaryotic SPARTA immune system.
Nat.Chem.Biol., 20, 2024
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7ETU
 | | The FK1 domain of FKBP51 in complex with peptide-inhibitor hit SFPFT | | Descriptor: | Peptidyl-prolyl cis-trans isomerase FKBP5, peptide-inhibitor hit | | Authors: | Han, J.T, Zhu, Y.C, Pan, D.B, Xue, H.X, Wang, S, Liu, H.X, He, Y.X, Yao, X.J. | | Deposit date: | 2021-05-14 | | Release date: | 2022-02-23 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.39 Å) | | Cite: | Discovery of pentapeptide-inhibitor hits targeting FKBP51 by combining computational modeling and X-ray crystallography.
Comput Struct Biotechnol J, 19, 2021
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7ETT
 | | The FK1 domain of FKBP51 in complex with peptide-inhibitor hit QFPFV | | Descriptor: | Peptidyl-prolyl cis-trans isomerase FKBP5, peptide-inhibitor hit | | Authors: | Han, J.T, Zhu, Y.C, Pan, D.B, Xue, H.X, Wang, S, Liu, H.X, He, Y.X, Yao, X.J. | | Deposit date: | 2021-05-14 | | Release date: | 2022-02-23 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Discovery of pentapeptide-inhibitor hits targeting FKBP51 by combining computational modeling and X-ray crystallography.
Comput Struct Biotechnol J, 19, 2021
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7ETV
 | | The FK1 domain of FKBP51 in complex with peptide-inhibitor hit DFPFV | | Descriptor: | Peptidyl-prolyl cis-trans isomerase FKBP5, peptide-inhibitor hit | | Authors: | Han, J.T, Zhu, Y.C, Pan, D.B, Xue, H.X, Wang, S, Liu, H.X, He, Y.X, Yao, X.J. | | Deposit date: | 2021-05-14 | | Release date: | 2022-02-23 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.31 Å) | | Cite: | Discovery of pentapeptide-inhibitor hits targeting FKBP51 by combining computational modeling and X-ray crystallography.
Comput Struct Biotechnol J, 19, 2021
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8J6M
 | | SIDT1 protein | | Descriptor: | CHOLESTEROL, Green fluorescent protein,SID1 transmembrane family member 1, OLEIC ACID, ... | | Authors: | Zhang, J.T, Jiang, D.H. | | Deposit date: | 2023-04-26 | | Release date: | 2024-05-01 | | Method: | ELECTRON MICROSCOPY (2.77 Å) | | Cite: | SIDT1 protein
To Be Published
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8IFM
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8IFL
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8IFK
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7EEA
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7EEQ
 | | Cyanophage Pam1 tail machine | | Descriptor: | Needle head proteins, Tailspike head-binding domain | | Authors: | Zhang, J.T, Jiang, Y.L, Zhou, C.Z. | | Deposit date: | 2021-03-19 | | Release date: | 2021-10-20 | | Last modified: | 2022-05-04 | | Method: | ELECTRON MICROSCOPY (3.96 Å) | | Cite: | Structure and assembly pattern of a freshwater short-tailed cyanophage Pam1.
Structure, 30, 2022
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7EEP
 | | Cyanophage Pam1 portal-adaptor complex | | Descriptor: | Pam1 adaptor proteins, Pam1 portal proteins | | Authors: | Zhang, J.T, Jiang, Y.L, Zhou, C.Z. | | Deposit date: | 2021-03-19 | | Release date: | 2021-10-20 | | Last modified: | 2022-05-04 | | Method: | ELECTRON MICROSCOPY (3.75 Å) | | Cite: | Structure and assembly pattern of a freshwater short-tailed cyanophage Pam1.
Structure, 30, 2022
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7EEL
 | | Cyanophage Pam1 capsid asymmetric unit | | Descriptor: | Cement (decoration) proteins, Major capsid proteins | | Authors: | Zhang, J.T, Jiang, Y.L, Zhou, C.Z. | | Deposit date: | 2021-03-19 | | Release date: | 2021-10-20 | | Last modified: | 2022-05-04 | | Method: | ELECTRON MICROSCOPY (3.26 Å) | | Cite: | Structure and assembly pattern of a freshwater short-tailed cyanophage Pam1.
Structure, 30, 2022
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5XEY
 | | Discovery and structural analysis of a phloretin hydrolase from the opportunistic pathogen Mycobacterium abscessus | | Descriptor: | 1-[2,4,6-tris(oxidanyl)phenyl]ethanone, phloretin hydrolase | | Authors: | He, Y.X, Han, J.T, Jia, W.J, Zhang, Z. | | Deposit date: | 2017-04-06 | | Release date: | 2018-05-02 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (1.82 Å) | | Cite: | Discovery and structural analysis of a phloretin hydrolase from the opportunistic human pathogen Mycobacterium abscessus.
FEBS J., 2019
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5XE5
 | | Discovery and structural analysis of a phloretin hydrolase from the opportunistic pathogen Mycobacterium abscessus | | Descriptor: | 1,2-ETHANEDIOL, MAGNESIUM ION, phloretin hydrolase | | Authors: | He, Y.X, Han, J.T, Jia, W.J, Zhang, Z. | | Deposit date: | 2017-04-01 | | Release date: | 2018-05-02 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.17 Å) | | Cite: | Discovery and structural analysis of a phloretin hydrolase from the opportunistic human pathogen Mycobacterium abscessus.
FEBS J., 2019
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7XEX
 | | Crystal strucutre of apoCasDinG | | Descriptor: | CasDinG | | Authors: | Zhang, J.T, Cui, N, Liu, Y.R, Huang, H.D, Jia, N. | | Deposit date: | 2022-03-31 | | Release date: | 2023-07-26 | | Last modified: | 2023-08-02 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Type IV-A CRISPR-Csf complex: Assembly, dsDNA targeting, and CasDinG recruitment.
Mol.Cell, 83, 2023
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7XF0
 | | Crystal strucutre of CasDinG in complex with ATP | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, CasDinG | | Authors: | Zhang, J.T, Cui, N, Liu, Y.R, Huang, H.D, Jia, N. | | Deposit date: | 2022-03-31 | | Release date: | 2023-07-26 | | Last modified: | 2023-08-02 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Type IV-A CRISPR-Csf complex: Assembly, dsDNA targeting, and CasDinG recruitment.
Mol.Cell, 83, 2023
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7XF1
 | | Crystal strucutre of apoCasDinG in complex with ssDNA | | Descriptor: | CasDinG, DNA (5'-D(*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3') | | Authors: | Zhang, J.T, Cui, N, Liu, Y.R, Huang, H.D, Jia, N. | | Deposit date: | 2022-03-31 | | Release date: | 2023-07-26 | | Last modified: | 2023-08-02 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Type IV-A CRISPR-Csf complex: Assembly, dsDNA targeting, and CasDinG recruitment.
Mol.Cell, 83, 2023
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