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2RAP
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BU of 2rap by Molmil
THE SMALL G PROTEIN RAP2A IN COMPLEX WITH GTP
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, RAP2A
Authors:Cherfils, J, Menetrey, J, Lebras, G.
Deposit date:1998-05-06
Release date:1998-06-17
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structures of the small G protein Rap2A in complex with its substrate GTP, with GDP and with GTPgammaS.
EMBO J., 16, 1997
1KAO
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BU of 1kao by Molmil
CRYSTAL STRUCTURE OF THE SMALL G PROTEIN RAP2A WITH GDP
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, RAP2A
Authors:Cherfils, J, Menetrey, J, Le Bras, G.
Deposit date:1997-08-01
Release date:1997-12-24
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structures of the small G protein Rap2A in complex with its substrate GTP, with GDP and with GTPgammaS.
EMBO J., 16, 1997
1NDC
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BU of 1ndc by Molmil
X-RAY STRUCTURE OF NUCLEOSIDE DIPHOSPHATE KINASE COMPLEXED WITH DTDP AND MG2+ AT 2 A RESOLUTION
Descriptor: MAGNESIUM ION, NUCLEOSIDE DIPHOSPHATE KINASE, THYMIDINE-5'-DIPHOSPHATE
Authors:Cherfils, J, Morera, S, Janin, J.
Deposit date:1994-04-27
Release date:1994-06-22
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:X-ray structure of nucleoside diphosphate kinase complexed with thymidine diphosphate and Mg2+ at 2-A resolution.
Biochemistry, 33, 1994
1PBV
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BU of 1pbv by Molmil
SEC7 DOMAIN OF THE EXCHANGE FACTOR ARNO
Descriptor: ARNO
Authors:Cherfils, J, Menetrey, J, Mathieu, M, Le Bras, G, Robineau, S, Beraud-Dufour, S, Antonny, B, Chardin, P.
Deposit date:1998-01-15
Release date:1999-03-09
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the Sec7 domain of the Arf exchange factor ARNO.
Nature, 392, 1998
1KDN
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BU of 1kdn by Molmil
STRUCTURE OF NUCLEOSIDE DIPHOSPHATE KINASE
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, MAGNESIUM ION, ...
Authors:Cherfils, J, Xu, Y.W, Morera, S, Janin, J.
Deposit date:1996-09-10
Release date:1997-04-21
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:AlF3 mimics the transition state of protein phosphorylation in the crystal structure of nucleoside diphosphate kinase and MgADP.
Proc.Natl.Acad.Sci.USA, 94, 1997
5N6O
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BU of 5n6o by Molmil
Wild type human Rac1-GDP
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ras-related C3 botulinum toxin substrate 1
Authors:Cherfils, J, Ferrandez, Y.
Deposit date:2017-02-15
Release date:2017-12-27
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Allosteric inhibition of the guanine nucleotide exchange factor DOCK5 by a small molecule.
Sci Rep, 7, 2017
2ANB
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BU of 2anb by Molmil
Crystal Structure Of Oligomeric E.coli Guanylate Kinase In Complex With GMP
Descriptor: GUANOSINE-5'-MONOPHOSPHATE, Guanylate kinase, SULFATE ION
Authors:Hible, G, Renault, L, Schaeffer, F, Christova, P, Radulescu, A.Z, Evrin, C, Gilles, A.M, Cherfils, J.
Deposit date:2005-08-11
Release date:2005-08-30
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Calorimetric and crystallographic analysis of the oligomeric structure of Escherichia coli GMP kinase
J.Mol.Biol., 352, 2005
4D7R
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BU of 4d7r by Molmil
Crystal structure of a chimeric protein with the Sec7 domain of Rickettsia prowazekii RalF and the capping domain of Legionella pneumophila RalF
Descriptor: PROLINE/BETAINE TRANSPORTER, RALF
Authors:Folly-Klan, M, Sancerne, B, Alix, E, Roy, C.R, Cherfils, J, Campanacci, V.
Deposit date:2014-11-27
Release date:2015-01-14
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:On the Use of Legionella/Rickettsia Chimeras to Investigate the Structure and Regulation of Rickettsia Effector Ralf.
J.Struct.Biol., 189, 2015
3RAP
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BU of 3rap by Molmil
The small G protein Rap2 in a non catalytic complex with GTP
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PROTEIN (G protein RAP2A)
Authors:Menetrey, J, Cherfils, J.
Deposit date:1999-05-31
Release date:1999-12-08
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of the small G protein Rap2 in a non-catalytic complex with GTP.
Proteins, 37, 1999
4Z68
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BU of 4z68 by Molmil
Hybrid structural analysis of the Arp2/3 regulator Arpin identifies its acidic tail as a primary binding epitope
Descriptor: GLU-ILE-ARG-GLU-GLN-GLY-ASP-GLY-ALA-GLU-ASP-GLU, SULFATE ION, Tankyrase-2
Authors:Fetics, S.K, Campanacci, V, Dang, I, Gautreau, A, Cherfils, J.
Deposit date:2015-04-04
Release date:2015-12-30
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.859 Å)
Cite:Hybrid Structural Analysis of the Arp2/3 Regulator Arpin Identifies Its Acidic Tail as a Primary Binding Epitope.
Structure, 24, 2016
3LTL
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BU of 3ltl by Molmil
Crystal structure of human BIG1 Sec7 domain
Descriptor: ACETIC ACID, Brefeldin A-inhibited guanine nucleotide-exchange protein 1, CALCIUM ION
Authors:Simister, P.C, Joubert, A, Cherfils, J, Biou, V.
Deposit date:2010-02-16
Release date:2011-04-13
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The Sec7 domain structures of human BIG1 and Cytohesin1 Arf nucleotide exchange factors
To be Published
2J5X
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BU of 2j5x by Molmil
STRUCTURE OF THE SMALL G PROTEIN ARF6 IN COMPLEX WITH GTPGAMMAS
Descriptor: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, ADP-RIBOSYLATION FACTOR 6, MAGNESIUM ION
Authors:Pasqualato, S, Menetrey, J, Franco, M, Cherfils, J.
Deposit date:2006-09-20
Release date:2006-09-21
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The Structural Gdp-GTP Cycle of Human Arf6.
Embo Rep., 2, 2001
4D7Q
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BU of 4d7q by Molmil
Crystal structure of a chimeric protein with the Sec7 domain of Legionella pneumophila RalF and the capping domain of Rickettsia prowazekii RalF
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
Authors:Folly-Klan, M, Sancerne, B, Alix, E, Roy, C.R, Cherfils, J, Campanacci, V.
Deposit date:2014-11-27
Release date:2015-01-14
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:On the Use of Legionella/Rickettsia Chimeras to Investigate the Structure and Regulation of Rickettsia Effector Ralf.
J.Struct.Biol., 189, 2015
3N5C
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BU of 3n5c by Molmil
Crystal Structure of Arf6DELTA13 complexed with GDP
Descriptor: ADP-ribosylation factor 6, CHLORIDE ION, GUANOSINE-5'-DIPHOSPHATE
Authors:Aizel, K, Biou, V, Cherfils, J.
Deposit date:2010-05-25
Release date:2010-08-18
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:SAXS and X-ray crystallography suggest an unfolding model for the GDP/GTP conformational switch of the small GTPase Arf6.
J.Mol.Biol., 402, 2010
1OIX
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BU of 1oix by Molmil
X-ray structure of the small G protein Rab11a in complex with GDP and Pi
Descriptor: CHLORIDE ION, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Pasqualato, S, Senic-Matuglia, F, Renault, L, Goud, B, Salamero, J, Cherfils, J.
Deposit date:2003-06-26
Release date:2005-01-25
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystallographic Evidence for Substrate-Assisted GTP Hydrolysis by a Small GTP Binding Protein
Structure, 13, 2005
2BEF
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BU of 2bef by Molmil
CRYSTAL STRUCTURE OF NDP KINASE COMPLEXED WITH MG, ADP, AND BEF3
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ...
Authors:Xu, Y.W, Cherfils, J.
Deposit date:1998-05-26
Release date:1998-08-12
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:AlF3 mimics the transition state of protein phosphorylation in the crystal structure of nucleoside diphosphate kinase and MgADP.
Proc.Natl.Acad.Sci.USA, 94, 1997
1KU1
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BU of 1ku1 by Molmil
Crystal Structure of the Sec7 Domain of Yeast GEA2
Descriptor: ARF guanine-nucleotide exchange factor 2
Authors:Renault, L, Christova, P, Guibert, B, Pasqualato, S, Cherfils, J.
Deposit date:2002-01-20
Release date:2002-03-27
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Mechanism of domain closure of Sec7 domains and role in BFA sensitivity.
Biochemistry, 41, 2002
5NLV
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BU of 5nlv by Molmil
Brag2 Sec7-PH (390-763)
Descriptor: IQ motif and SEC7 domain-containing protein 1
Authors:Nawrotek, A, Cherfils, J.
Deposit date:2017-04-05
Release date:2017-09-27
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Multiple interactions between an Arf/GEF complex and charged lipids determine activation kinetics on the membrane.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5NLY
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BU of 5nly by Molmil
Brag2 Sec7-PH (390-763), P212121
Descriptor: IQ motif and SEC7 domain-containing protein 1, PHOSPHATE ION
Authors:Nawrotek, A, Cherfils, J.
Deposit date:2017-04-05
Release date:2017-09-27
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2 Å)
Cite:Multiple interactions between an Arf/GEF complex and charged lipids determine activation kinetics on the membrane.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
1S9D
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BU of 1s9d by Molmil
ARF1[DELTA 1-17]-GDP-MG IN COMPLEX WITH BREFELDIN A AND A SEC7 DOMAIN
Descriptor: 1,6,7,8,9,11A,12,13,14,14A-DECAHYDRO-1,13-DIHYDROXY-6-METHYL-4H-CYCLOPENT[F]OXACYCLOTRIDECIN-4-ONE, ADP-Ribosylation Factor 1, Arno, ...
Authors:Renault, L, Guibert, B, Cherfils, J.
Deposit date:2004-02-04
Release date:2004-02-10
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Snapshots of the Mechanism and Inhibition of a Guanine Nucleotide Exchange Factor
Nature, 426, 2003
1R8S
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BU of 1r8s by Molmil
ARF1[DELTA1-17]-GDP IN COMPLEX WITH A SEC7 DOMAIN CARRYING THE MUTATION OF THE CATALYTIC GLUTAMATE TO LYSINE
Descriptor: ADP-ribosylation factor 1, Arno, BETA-MERCAPTOETHANOL, ...
Authors:Renault, L, Guibert, B, Cherfils, J.
Deposit date:2003-10-28
Release date:2004-01-20
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.46 Å)
Cite:Structural snapshots of the mechanism and inhibition of a guanine nucleotide exchange factor
Nature, 426, 2003
1ZNY
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BU of 1zny by Molmil
Crystal Structure Of Mycobacterium tuberculosis Guanylate Kinase In Complex With GDP
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Guanylate kinase
Authors:Hible, G, Christova, P, Renault, L, Seclaman, E, Thompson, A, Girard, E, Munier-Lehmann, H, Cherfils, J.
Deposit date:2005-05-12
Release date:2005-11-29
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Unique GMP-binding site in Mycobacterium tuberculosis guanosine monophosphate kinase
Proteins, 62, 2006
1ZNZ
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BU of 1znz by Molmil
Crystal Structure Of The Reduced Form Of Mycobacterium tuberculosis Guanylate Kinase In Complex With GDP
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Guanylate kinase
Authors:Hible, G, Christova, P, Renault, L, Seclaman, E, Thompson, A, Girard, E, Munier-Lehmann, H, Cherfils, J.
Deposit date:2005-05-12
Release date:2005-11-29
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Unique GMP-binding site in Mycobacterium tuberculosis guanosine monophosphate kinase
Proteins, 62, 2006
1ZNX
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BU of 1znx by Molmil
Crystal Structure Of Mycobacterium tuberculosis Guanylate Kinase In Complex With GMP
Descriptor: GUANOSINE-5'-MONOPHOSPHATE, Guanylate kinase
Authors:Hible, G, Christova, P, Renault, L, Seclaman, E, Thompson, A, Girard, E, Munier-Lehmann, H, Cherfils, J.
Deposit date:2005-05-12
Release date:2005-11-29
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Unique GMP-binding site in Mycobacterium tuberculosis guanosine monophosphate kinase
Proteins, 62, 2006
1ZNW
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Crystal Structure Of Unliganded Form Of Mycobacterium tuberculosis Guanylate Kinase
Descriptor: Guanylate kinase
Authors:Hible, G, Christova, P, Renault, L, Seclaman, E, Thompson, A, Girard, E, Munier-Lehmann, H, Cherfils, J.
Deposit date:2005-05-12
Release date:2005-11-29
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Unique GMP-binding site in Mycobacterium tuberculosis guanosine monophosphate kinase
Proteins, 62, 2006

 

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