Author results

1AMU
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PHENYLALANINE ACTIVATING DOMAIN OF GRAMICIDIN SYNTHETASE 1 IN A COMPLEX WITH AMP AND PHENYLALANINE
分子名称:GRAMICIDIN SYNTHETASE 1, MAGNESIUM ION, SULFATE ION, ...
著者Conti, E., Stachelhaus, T., Marahiel, M.A., Brick, P.
登録日1997-06-18
公開日1998-07-01
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis for the activation of phenylalanine in the non-ribosomal biosynthesis of gramicidin S.
EMBO J., 16, 1997
1DNY
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SOLUTION STRUCTURE OF PCP, A PROTOTYPE FOR THE PEPTIDYL CARRIER DOMAINS OF MODULAR PEPTIDE SYNTHETASES
分子名称:NON-RIBOSOMAL PEPTIDE SYNTHETASE PEPTIDYL CARRIER PROTEIN
著者Weber, T., Baumgartner, R., Renner, C., Marahiel, M.A., Holak, T.A.
登録日1999-12-17
公開日2000-05-17
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Solution structure of PCP, a prototype for the peptidyl carrier domains of modular peptide synthetases.
Structure Fold.Des., 8, 2000
1JMK
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STRUCTURAL BASIS FOR THE CYCLIZATION OF THE LIPOPEPTIDE ANTIBIOTIC SURFACTIN BY THE THIOESTERASE DOMAIN SRFTE
分子名称:Surfactin Synthetase, SULFATE ION
著者Bruner, S.D., Weber, T., Kohli, R.M., Schwarzer, D., Marahiel, M.A., Walsh, C.T., Stubbs, M.T.
登録日2001-07-18
公開日2002-03-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献Structural basis for the cyclization of the lipopeptide antibiotic surfactin by the thioesterase domain SrfTE.
Structure, 10, 2002
1MD9
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CRYSTAL STRUCTURE OF DHBE IN COMPLEX WITH DHB AND AMP
分子名称:2,3-dihydroxybenzoate-AMP ligase, ADENOSINE MONOPHOSPHATE, 2,3-DIHYDROXY-BENZOIC ACID
著者May, J.J., Kessler, N., Marahiel, M.A., Stubbs, M.T.
登録日2002-08-07
公開日2002-09-11
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of DhbE, an archetype for aryl acid activating domains of modular nonribosomal peptide synthetases.
Proc.Natl.Acad.Sci.USA, 99, 2002
1MDB
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CRYSTAL STRUCTURE OF DHBE IN COMPLEX WITH DHB-ADENYLATE
分子名称:2,3-dihydroxybenzoate-AMP ligase, SULFATE ION, ADENOSINE MONOPHOSPHATE, ...
著者May, J.J., Kessler, N., Marahiel, M.A., Stubbs, M.T.
登録日2002-08-07
公開日2002-09-11
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Crystal structure of DhbE, an archetype for aryl acid activating domains of modular nonribosomal peptide synthetases.
Proc.Natl.Acad.Sci.USA, 99, 2002
1MDF
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CRYSTAL STRUCTURE OF DHBE IN ABSENCE OF SUBSTRATE
分子名称:2,3-dihydroxybenzoate-AMP ligase, SULFATE ION
著者May, J.J., Kessler, N., Marahiel, M.A., Stubbs, M.T.
登録日2002-08-07
公開日2002-09-11
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of DhbE, an archetype for aryl acid activating domains of modular nonribosomal peptide synthetases.
Proc.Natl.Acad.Sci.USA, 99, 2002
2CB9
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CRYSTAL STRUCTURE OF THE THIOESTERASE DOMAIN OF THE FENGYCIN BIOSYNTHESIS CLUSTER
分子名称:FENGYCIN SYNTHETASE, ACETIC ACID
著者Samel, S., Marahiel, M.A., Essen, L.-O.
登録日2006-01-03
公開日2007-03-06
最終更新日2017-07-05
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The Thioesterase Domain of the Fengycin Biosynthesis Cluster: A Structural Base for the Macrocyclization of a Non-Ribosomal Lipopeptide
J.Mol.Biol., 359, 2006
2CBG
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CRYSTAL STRUCTURE OF THE PMSF-INHIBITED THIOESTERASE DOMAIN OF THE FENGYCIN BIOSYNTHESIS CLUSTER
分子名称:FENGYCIN SYNTHETASE, phenylmethanesulfonic acid
著者Samel, S., Marahiel, M.A., Essen, L.-O.
登録日2006-01-03
公開日2007-03-06
最終更新日2017-07-05
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The Thioesterase Domain of the Fengycin Biosynthesis Cluster: A Structural Base for the Macrocyclization of a Non-Ribosomal Lipopeptide
J.Mol.Biol., 359, 2006
2GDW
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SOLUTION STRUCTURE OF THE B. BREVIS TYCC3-PCP IN A/H-STATE
分子名称:Tyrocidine synthetase III
著者Koglin, A., Loehr, F., Rogov, V.V., Marahiel, M.A., Bernhard, F., Doetsch, V.
登録日2006-03-17
公開日2006-08-01
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Conformational switches modulate protein interactions in peptide antibiotic synthetases
Science, 312, 2006
2GDX
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SOLUTION STRUCTURE OF THE B. BREVIS TYCC3-PCP IN H-STATE
分子名称:Tyrocidine synthetase III
著者Koglin, A., Loehr, F., Rogov, V.V., Marahiel, M.A., Bernhard, F., Doetsch, V.
登録日2006-03-17
公開日2006-08-01
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Conformational switches modulate protein interactions in peptide antibiotic synthetases
Science, 312, 2006
2GDY
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SOLUTION STRUCTURE OF THE B. BREVIS TYCC3-PCP IN A-STATE
分子名称:Tyrocidine synthetase III
著者Koglin, A., Loehr, F., Rogov, V.V., Marahiel, M.A., Bernhard, F., Doetsch, V.
登録日2006-03-17
公開日2006-08-01
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Conformational switches modulate protein interactions in peptide antibiotic synthetases
Science, 312, 2006
2JGP
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STRUCTURE OF THE TYCC5-6 PCP-C BIDOMAIN OF THE TYROCIDINE SYNTHETASE TYCC
分子名称:TYROCIDINE SYNTHETASE 3, SULFATE ION, 1,4-DIETHYLENE DIOXIDE, ...
著者Samel, S.A., Schoenafinger, G., Knappe, T.A., Marahiel, M.A., Essen, L.-O.
登録日2007-02-13
公開日2007-10-30
最終更新日2019-07-24
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural and Functional Insights Into a Peptide Bond-Forming Bidomain from a Nonribosomal Peptide Synthetase.
Structure, 15, 2007
2K2Q
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COMPLEX STRUCTURE OF THE EXTERNAL THIOESTERASE OF THE SURFACTIN-SYNTHETASE WITH A CARRIER DOMAIN
分子名称:Tyrocidine synthetase 3 (Tyrocidine synthetase III), Surfactin synthetase thioesterase subunit
著者Koglin, A., Lohr, F., Bernhard, F., Rogov, V.V., Frueh, D.P., Strieter, E.R., Mofid, M.R., Guntert, P., Wagner, G., Walsh, C.T., Marahiel, M.A., Dotsch, V.
登録日2008-04-10
公開日2008-12-09
最終更新日2018-01-24
実験手法SOLUTION NMR
主引用文献Structural basis for the selectivity of the external thioesterase of the surfactin synthetase.
Nature, 454, 2008
2LX6
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STRUCTURE OF LASSO PEPTIDE CAULOSEGNIN I
分子名称:Putative uncharacterized protein
著者Hegemann, J.D., Zimmermann, M., Xie, X., Marahiel, M.A.
登録日2012-08-15
公開日2012-12-26
最終更新日2013-01-23
実験手法SOLUTION NMR
主引用文献Caulosegnins I-III: A Highly Diverse Group of Lasso Peptides Derived from a Single Biosynthetic Gene Cluster.
J.Am.Chem.Soc., 135, 2013
2M37
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STRUCTURE OF LASSO PEPTIDE ASTEXIN-1
分子名称:ASTEXIN-1
著者Zimmermann, M., Hegemann, J.D., Xie, X., Marahiel, M.A.
登録日2013-01-14
公開日2013-05-01
実験手法SOLUTION NMR
主引用文献The astexin-1 lasso peptides: biosynthesis, stability, and structural studies.
Chem.Biol., 20, 2013
2MD9
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SOLUTION STRUCTURE OF AN ACTIVE SITE MUTANT PEPITDYL CARRIER PROTEIN
分子名称:Tyrocidine synthase 3
著者Tufar, P., Rahighi, S., Kraas, F.I., Kirchner, D.K., Loehr, F., Henrich, E., Koepke, J., Dikic, I., Guentert, P., Marahiel, M.A., Doetsch, V.
登録日2013-09-06
公開日2014-04-23
最終更新日2017-11-29
実験手法SOLUTION NMR
主引用文献Crystal Structure of a PCP/Sfp Complex Reveals the Structural Basis for Carrier Protein Posttranslational Modification.
Chem.Biol., 21, 2014
2MFV
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STRUCTURE OF LASSO PEPTIDE XANTHOMONIN II
分子名称:Xanthomonin II
著者Hegemann, J.D., Zimmermann, M., Harms, K., Xie, X., Marahiel, M.A.
登録日2013-10-23
公開日2014-10-29
実験手法SOLUTION NMR
主引用文献Xanthomonin I-III are Lasso Peptides Featuring Macrolactam Rings Consisting of Only Seven Amino Acids
To be Published
2MLJ
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STRUCTURE OF LASSO PEPTIDE CAULONODIN V
分子名称:Caulonodin V
著者Zimmermann, M., Hegemann, J.D., Xie, X., Marahiel, M.A.
登録日2014-02-28
公開日2015-01-14
実験手法SOLUTION NMR
主引用文献Characterization of caulonodin lasso peptides revealed unprecedented N-terminal residues and a precursor motif essential for peptide maturation
CHEM SCI, 5, 2014
2MMT
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LASSO PEPTIDE-BASED INTEGRIN INHIBITOR: MICROCIN J25 VARIANT WITH RGDF SUBSTITUTION OF GLY12-ILE13-GLY14-THR15
分子名称:Microcin J25 RGDF mutant
著者Hegemann, J.D., Zimmermann, M., Knappe, T.A., Xie, X., Marahiel, M.A.
登録日2014-03-18
公開日2014-07-02
最終更新日2014-07-23
実験手法SOLUTION NMR
主引用文献Rational improvement of the affinity and selectivity of integrin binding of grafted lasso peptides.
J.Med.Chem., 57, 2014
2MMW
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LASSO PEPTIDE BASED INTEGRIN INHIBITOR: MICROCIN J25 VARIANT WITH RGD SUBSTITUTION OF GLY12-ILE13-GLY14
分子名称:Microcin J25
著者Knappe, T.A., Linne, U., Xie, X., Marahiel, M.A.
登録日2014-03-20
公開日2014-05-14
実験手法SOLUTION NMR
主引用文献Introducing lasso peptides as molecular scaffolds for drug design: engineering of an integrin antagonist.
Angew.Chem.Int.Ed.Engl., 50, 2011
2RON
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THE EXTERNAL THIOESTERASE OF THE SURFACTIN-SYNTHETASE
分子名称:Surfactin synthetase thioesterase subunit
著者Koglin, A., Lohr, F., Bernhard, F., Rogov, V.V., Frueh, D.P., Strieter, E.R., Mofid, M.R., Guentert, P., Wagner, G., Walsh, C.T., Marahiel, M.A., Doetsch, V.
登録日2008-04-04
公開日2008-08-12
最終更新日2016-10-26
実験手法SOLUTION NMR
主引用文献Structural basis for the selectivity of the external thioesterase of the surfactin synthetase
Nature, 454, 2008
2VSQ
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STRUCTURE OF SURFACTIN A SYNTHETASE C (SRFA-C), A NONRIBOSOMAL PEPTIDE SYNTHETASE TERMINATION MODULE
分子名称:SURFACTIN SYNTHETASE SUBUNIT 3, LEUCINE, SULFATE ION
著者Tanovic, A., Samel, S.A., Essen, L.-O., Marahiel, M.A.
登録日2008-04-29
公開日2008-07-08
最終更新日2019-01-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of the termination module of a nonribosomal peptide synthetase.
Science, 321, 2008
2WBO
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CRYSTAL STRUCTURE OF VIOC IN COMPLEX WITH L-ARGININE
分子名称:L-ARGININE BETA-HYDROXYLASE, ARGININE, FE (II) ION, ...
著者Helmetag, V., Samel, S.A., Thomas, M.G., Marahiel, M.A., Essen, L.-O.
登録日2009-03-02
公開日2009-06-23
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Structural Basis for the Erythro-Stereospecificity of the L-Arginine Oxygenase Vioc in Viomycin Biosynthesis.
FEBS J., 276, 2009
2WBP
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CRYSTAL STRUCTURE OF VIOC IN COMPLEX WITH FE(II), (2S,3S)- HYDROXYARGININE, AND SUCCINATE
分子名称:L-ARGININE BETA-HYDROXYLASE, ARGININE, FE (II) ION, ...
著者Helmetag, V., Samel, S.A., Thomas, M.G., Marahiel, M.A., Essen, L.-O.
登録日2009-03-02
公開日2009-06-23
最終更新日2013-05-08
実験手法X-RAY DIFFRACTION (1.16 Å)
主引用文献Structural Basis for the Erythro-Stereospecificity of the L-Arginine Oxygenase Vioc in Viomycin Biosynthesis.
FEBS J., 276, 2009
2WBQ
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CRYSTAL STRUCTURE OF VIOC IN COMPLEX WITH (2S,3S)-HYDROXYARGININE
分子名称:L-ARGININE BETA-HYDROXYLASE, ACETATE ION, (2S,3S)-3-HYDROXYARGININE
著者Helmetag, V., Samel, S.A., Thomas, M.G., Marahiel, M.A., Essen, L.-O.
登録日2009-03-02
公開日2009-06-23
最終更新日2013-05-08
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Structural Basis for the Erythro-Stereospecificity of the L-Arginine Oxygenase Vioc in Viomycin Biosynthesis.
FEBS J., 276, 2009
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