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3TV0
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STRUCTURE OF DYNACTIN P27 SUBUNIT
分子名称:Dynactin subunit 6
著者Derewenda, Z.S., Derewenda, U., Kowalska, A.
登録日2011-09-19
公開日2012-10-03
実験手法X-RAY DIFFRACTION (2.1492 Å)
主引用文献Dynactin targets Polo-like kinase 1 to kinetochores
To be Published
4TGL
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CATALYSIS AT THE INTERFACE: THE ANATOMY OF A CONFORMATIONAL CHANGE IN A TRIGLYCERIDE LIPASE
分子名称:TRIACYL-GLYCEROL ACYLHYDROLASE, DIETHYL PHOSPHONATE
著者Derewenda, U., Brzozowski, A.M., Lawson, D., Derewenda, Z.S.
登録日1991-07-29
公開日1993-07-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Catalysis at the interface: the anatomy of a conformational change in a triglyceride lipase.
Biochemistry, 31, 1992
1TIB
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CONFORMATIONAL LABILITY OF LIPASES OBSERVED IN THE ABSENCE OF AN OIL-WATER INTERFACE: CRYSTALLOGRAPHIC STUDIES OF ENZYMES FROM THE FUNGI HUMICOLA LANUGINOSA AND RHIZOPUS DELEMAR
分子名称:LIPASE
著者Derewenda, U., Swenson, L., Wei, Y., Derewenda, Z.S.
登録日1993-12-06
公開日1995-01-26
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Conformational lability of lipases observed in the absence of an oil-water interface: crystallographic studies of enzymes from the fungi Humicola lanuginosa and Rhizopus delemar.
J.Lipid Res., 35, 1994
1TIC
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CONFORMATIONAL LABILITY OF LIPASES OBSERVED IN THE ABSENCE OF AN OIL-WATER INTERFACE: CRYSTALLOGRAPHIC STUDIES OF ENZYMES FROM THE FUNGI HUMICOLA LANUGINOSA AND RHIZOPUS DELEMAR
分子名称:LIPASE
著者Derewenda, U., Swenson, L., Green, R., Joerger, R., Haas, M.J., Derewenda, Z.S.
登録日1993-12-06
公開日1995-01-26
最終更新日2016-11-09
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Conformational lability of lipases observed in the absence of an oil-water interface: crystallographic studies of enzymes from the fungi Humicola lanuginosa and Rhizopus delemar.
J.Lipid Res., 35, 1994
3TGL
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STRUCTURE AND MOLECULAR MODEL REFINEMENT OF RHIZOMUCOR MIEHEI TRIACYLGLYCERIDE LIPASE: A CASE STUDY OF THE USE OF SIMULATED ANNEALING IN PARTIAL MODEL REFINEMENT
分子名称:TRIACYL-GLYCEROL ACYLHYDROLASE
著者Brady, L., Brzozowski, A.M., Derewenda, Z.S., Dodson, E.J., Dodson, G.G., Tolley, S.P., Turkenburg, J.P., Christiansen, L., Huge-Jensen, B., Norskov, L., Thim, L.
登録日1991-07-29
公開日1993-07-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献STRUCTURE AND MOLECULAR-MODEL REFINEMENT OF RHIZOMUCOR-MIEHEI TRIACYLGLYCERIDE LIPASE - A CASE-STUDY OF THE USE OF SIMULATED ANNEALING IN PARTIAL MODEL REFINEMENT.
Acta Crystallogr.,Sect.B, 48, 1992
1CC0
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CRYSTAL STRUCTURE OF THE RHOA.GDP-RHOGDI COMPLEX
分子名称:transforming protein rhoA, rho GDP dissociation inhibitor alpha, MAGNESIUM ION, ...
著者Longenecker, K.L., Read, P., Derewenda, U., Dauter, Z., Garrard, S., Walker, L., Somlyo, A.V., Somlyo, A.P., Nakamoto, R.K., Derewenda, Z.S.
登録日1999-03-03
公開日2000-01-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (5 Å)
主引用文献How RhoGDI binds Rho.
Acta Crystallogr.,Sect.D, 55, 1999
1E0V
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XYLANASE 10A FROM SREPTOMYCES LIVIDANS. CELLOBIOSYL-ENZYME INTERMEDIATE AT 1.7 A
分子名称:ENDO-1,4-BETA-XYLANASE A, 2-DEOXY-2-FLUORO-B-D-CELLOBIOSIDE
著者Ducros, V., Charnock, S.J., Derewenda, U., Derewenda, Z.S., Dauter, Z., Dupont, C., Shareck, F., Morosoli, R., Kluepfel, D., Davies, G.J.
登録日2000-04-10
公開日2001-04-05
最終更新日2014-02-05
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Substrate Specificity in Glycoside Hydrolase Family 10. Structural and Kinetic Analysis of the Streptomyces Lividans Xylanase 10A
J.Biol.Chem., 275, 2000
1E0W
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XYLANASE 10A FROM SREPTOMYCES LIVIDANS. NATIVE STRUCTURE AT 1.2 ANGSTROM RESOLUTION
分子名称:ENDO-1,4-BETA-XYLANASE A
著者Ducros, V., Charnock, S.J., Derewenda, U., Derewenda, Z.S., Dauter, Z., Dupont, C., Shareck, F., Morosoli, R., Kluepfel, D., Davies, G.J.
登録日2000-04-10
公開日2001-04-05
最終更新日2014-02-05
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Substrate Specificity in Glycoside Hydrolase Family 10. Structural and Kinetic Analysis of the Streptomyces Lividans Xylanase 10A
J.Biol.Chem., 275, 2000
1E0X
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XYLANASE 10A FROM SREPTOMYCES LIVIDANS. XYLOBIOSYL-ENZYME INTERMEDIATE AT 1.65 A
分子名称:ENDO-1,4-BETA-XYLANASE A, GLYCEROL, 2-DEOXY-2-FLUORO XYLOPYRANOSE, ...
著者Ducros, V., Charnock, S.J., Derewenda, U., Derewenda, Z.S., Dauter, Z., Dupont, C., Shareck, F., Morosoli, R., Kluepfel, D., Davies, G.J.
登録日2000-04-10
公開日2001-04-05
最終更新日2011-08-31
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Substrate Specificity in Glycoside Hydrolase Family 10. Structural and Kinetic Analysis of the Streptomyces Lividans Xylanase 10A
J.Biol.Chem., 275, 2000
1ESC
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THE MOLECULAR MECHANISM OF ENANTIORECOGNITION BY ESTERASES
分子名称:ESTERASE
著者Wei, Y., Schottel, J.L., Derewenda, U., Swenson, L., Patkar, S., Derewenda, Z.S.
登録日1994-10-07
公開日1995-10-15
最終更新日2019-07-17
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献A novel variant of the catalytic triad in the Streptomyces scabies esterase.
Nat.Struct.Biol., 2, 1995
1F7C
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CRYSTAL STRUCTURE OF THE BH DOMAIN FROM GRAF, THE GTPASE REGULATOR ASSOCIATED WITH FOCAL ADHESION KINASE
分子名称:RHOGAP PROTEIN
著者Longenecker, K.L., Derewenda, U., Sheffield, P.J., Zheng, Y., Derewenda, Z.S.
登録日2000-06-26
公開日2000-12-20
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of the BH domain from graf and its implications for Rho GTPase recognition.
J.Biol.Chem., 275, 2000
1TIA
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AN UNUSUAL BURIED POLAR CLUSTER IN A FAMILY OF FUNGAL LIPASES
分子名称:LIPASE
著者Derewenda, U., Swenson, L., Yamaguchi, S., Wei, Y., Derewenda, Z.S.
登録日1993-12-06
公開日1995-01-26
最終更新日2019-07-17
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献An unusual buried polar cluster in a family of fungal lipases.
Nat.Struct.Biol., 1, 1994
5DSD
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THE CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF EBOLA (BUNDIBUGYO) NUCLEOPROTEIN
分子名称:Nucleoprotein, GLYCEROL, CHLORIDE ION
著者Baker, L., Handing, K.B., Utepbergenov, D., Derewenda, U., Derewenda, Z.S.
登録日2015-09-17
公開日2015-09-30
最終更新日2018-01-17
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Molecular architecture of the nucleoprotein C-terminal domain from the Ebola and Marburg viruses.
Acta Crystallogr D Struct Biol, 72, 2016
5E2X
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THE CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF EBOLA (TAI FOREST) NUCLEOPROTEIN
分子名称:NP, NONAETHYLENE GLYCOL
著者Baker, L.E., Handing, K.B., Derewenda, U., Utepbergenov, D., Derewenda, Z.S.
登録日2015-10-01
公開日2015-10-21
最終更新日2018-01-17
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Molecular architecture of the nucleoprotein C-terminal domain from the Ebola and Marburg viruses.
Acta Crystallogr D Struct Biol, 72, 2016
1MJD
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STRUCTURE OF N-TERMINAL DOMAIN OF HUMAN DOUBLECORTIN
分子名称:DOUBLECORTIN
著者Kim, M.H., Cierpicki, T., Derewenda, U., Krowarsch, D., Feng, Y., Devedjiev, Y., Dauter, Z., Walsh, C.A., Otlewski, J., Bushweller, J.H., Derewenda, Z.S.
登録日2002-08-27
公開日2003-04-29
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献The DCX-domain Tandems of Doublecortin and Doublecortin-like Kinase
Nat.Struct.Biol., 10, 2003
5TGL
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A MODEL FOR INTERFACIAL ACTIVATION IN LIPASES FROM THE STRUCTURE OF A FUNGAL LIPASE-INHIBITOR COMPLEX
分子名称:LIPASE, N-HEXYLPHOSPHONATE ETHYL ESTER
著者Brzozowski, A.M., Derewenda, U., Derewenda, Z.S., Dodson, G.G., Lawson, D., Turkenburg, J.P., Bjorkling, F., Huge-Jensen, B., Patkar, S.R., Thim, L.
登録日1991-10-30
公開日1994-01-31
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献A model for interfacial activation in lipases from the structure of a fungal lipase-inhibitor complex.
Nature, 351, 1991
1C8U
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CRYSTAL STRUCTURE OF THE E.COLI THIOESTERASE II, A HOMOLOGUE OF THE HUMAN NEF-BINDING ENZYME
分子名称:ACYL-COA THIOESTERASE II, LAURYL DIMETHYLAMINE-N-OXIDE
著者Li, J., Derewenda, Z.S.
登録日1999-07-29
公開日2000-07-14
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of the Escherichia coli thioesterase II, a homolog of the human Nef binding enzyme.
Nat.Struct.Biol., 7, 2000
1ZNJ
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INSULIN, MONOCLINIC CRYSTAL FORM
分子名称:INSULIN, PHENOL, ZINC ION, ...
著者Turkenburg, M.G.W., Whittingham, J.L., Turkenburg, J.P., Dodson, G.G., Derewenda, U., Smith, G.D., Dodson, E.J., Derewenda, Z.S., Xiao, B.
登録日1997-09-23
公開日1998-01-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure Determination and Refinement of Two Crystal Forms of Native Insulins
To be Published
1ES9
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X-RAY CRYSTAL STRUCTURE OF R22K MUTANT OF THE MAMMALIAN BRAIN PLATELET-ACTIVATING FACTOR ACETYLHYDROLASES (PAF-AH)
分子名称:PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE IB GAMMA SUBUNIT
著者McMullen, T.W.P., Li, J., Sheffield, P.J., Aoki, J., Martin, T.W., Arai, H., Inoue, K., Derewenda, Z.S.
登録日2000-04-07
公開日2000-05-31
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献The functional implications of the dimerization of the catalytic subunits of the mammalian brain platelet-activating factor acetylhydrolase (Ib).
Protein Eng., 13, 2000
1ESD
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THE MOLECULAR MECHANISM OF ENANTIORECOGNITION BY ESTERASES
分子名称:ESTERASE, METHYLPHOSPHONIC ACID ESTER GROUP
著者Wei, Y., Schottel, J.L., Derewenda, U., Swenson, L., Patkar, S., Derewenda, Z.S.
登録日1994-10-07
公開日1995-10-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A novel variant of the catalytic triad in the Streptomyces scabies esterase.
Nat.Struct.Biol., 2, 1995
1ESE
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THE MOLECULAR MECHANISM OF ENANTIORECOGNITION BY ESTERASES
分子名称:ESTERASE, DIETHYL PHOSPHONATE
著者Wei, Y., Schottel, J.L., Derewenda, U., Swenson, L., Patkar, S., Derewenda, Z.S.
登録日1994-10-07
公開日1995-10-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献A novel variant of the catalytic triad in the Streptomyces scabies esterase.
Nat.Struct.Biol., 2, 1995
1FTN
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CRYSTAL STRUCTURE OF THE HUMAN RHOA/GDP COMPLEX
分子名称:TRANSFORMING PROTEIN RHOA (H12), MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE
著者Wei, Y., Zhang, Y., Derewenda, U., Liu, X., Minor, W., Nakamoto, R.K., Somlyo, A.V., Somlyo, A.P., Derewenda, Z.S.
登録日1997-03-13
公開日1998-03-18
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of RhoA-GDP and its functional implications.
Nat.Struct.Biol., 4, 1997
1JKM
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BREFELDIN A ESTERASE, A BACTERIAL HOMOLOGUE OF HUMAN HORMONE SENSITIVE LIPASE
分子名称:BREFELDIN A ESTERASE
著者Wei, Y., Contreras, A.J., Sheffield, P., Osterlund, T., Derewenda, U., Matern, U.O., Derewenda, Z.S.
登録日1998-02-04
公開日1999-02-16
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal structure of brefeldin A esterase, a bacterial homolog of the mammalian hormone-sensitive lipase.
Nat.Struct.Biol., 6, 1999
1KLL
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MOLECULAR BASIS OF MITOMYCIN C RESICTANCE IN STREPTOMYCES: CRYSTAL STRUCTURES OF THE MRD PROTEIN WITH AND WITHOUT A DRUG DERIVATIVE
分子名称:mitomycin-binding protein, 1,2-CIS-1-HYDROXY-2,7-DIAMINO-MITOSENE
著者Martin, T.W., Dauter, Z., Devedjiev, Y., Sheffield, P., Jelen, F., He, M., Sherman, D., Otlewski, J., Derewenda, Z.S., Derewenda, U.
登録日2001-12-12
公開日2002-07-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Molecular basis of mitomycin C resistance in streptomyces: structure and function of the MRD protein.
Structure, 10, 2002
1KMZ
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MOLECULAR BASIS OF MITOMYCIN C RESICTANCE IN STREPTOMYCES: CRYSTAL STRUCTURES OF THE MRD PROTEIN WITH AND WITHOUT A DRUG DERIVATIVE
分子名称:mitomycin-binding protein
著者Martin, T.W., Dauter, Z., Devedjiev, Y., Sheffield, P., Jelen, F., He, M., Sherman, D., Otlewski, J., Derewenda, Z.S., Derewenda, U.
登録日2001-12-17
公開日2002-07-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Molecular basis of mitomycin C resistance in streptomyces: structure and function of the MRD protein.
Structure, 10, 2002