Author results

3DZW
  • Download 3dzw
  • View 3dzw
Molmil generated image of 3dzw
STRUCTURE OF NARCISSUS PSEUDONARCISSUS LECTIN COMPLEX WITH MANNOBIOSE AT 1.7 A RESOLUTION, FORM II
Descriptor:Agglutinin, ALPHA-D-MANNOSE, PHOSPHATE ION
Authors:Rizkallah, P.J., Ozbey, S., Sauerborn, M.K.
Deposit date:2008-07-30
Release date:2009-08-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of Narcissus pseudonarcissus lectin complex with Mannobiose at 1.7 A resolution, form II
To be Published
4Z77
  • Download 4z77
  • View 4z77
Molmil generated image of 4z77
WEAK TCR BINDING TO AN UNSTABLE INSULIN EPITOPE DRIVES TYPE 1 DIABETES
Descriptor:H-2 class I histocompatibility antigen, K-D alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Cole, D.K.
Deposit date:2015-04-06
Release date:2015-06-24
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Weak TCR binding to an unstable insulin epitope drives type 1 diabetes
To Be Published
5NPZ
  • Download 5npz
  • View 5npz
Molmil generated image of 5npz
PORCINE (SUS SCROFA) MAJOR HISTOCOMPATIBILITY COMPLEX, CLASS I, PRESENTING EFEDLTFLA
Descriptor:MHC class I antigen, Beta-2-microglobulin, GLU-PHE-GLU-ASP-LEU-THR-PHE-LEU-ALA, ...
Authors:Rizkallah, P.J., Tungatt, K., Sewell, A.K.
Deposit date:2017-04-19
Release date:2018-05-02
Method:X-RAY DIFFRACTION (1.43 Å)
Cite:human T-cell Receptor
To Be Published
5NQ0
  • Download 5nq0
  • View 5nq0
Molmil generated image of 5nq0
PORCINE (SUS SCROFA) MAJOR HISTOCOMPATIBILITY COMPLEX, CLASS I, PRESENTING DFEREGYSL
Descriptor:MHC class I antigen, Beta-2-microglobulin, ASP-PHE-GLU-ARG-GLU-GLY-TYR-SER-LEU, ...
Authors:Rizkallah, P.J., Tungatt, K., Sewell, A.K.
Deposit date:2017-04-19
Release date:2018-04-25
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:SLA
To Be Published
5NQ1
  • Download 5nq1
  • View 5nq1
Molmil generated image of 5nq1
PORCINE (SUS SCROFA) MAJOR HISTOCOMPATIBILITY COMPLEX, CLASS I, WITH HUMAN BETA2 MICRO GLOBULIN, PRESENTING DFEREGYSL
Descriptor:MHC class I antigen, Beta-2-microglobulin, ASP-PHE-GLU-ARG-GLU-GLY-TYR-SER-LEU, ...
Authors:Rizkallah, P.J., Tungatt, K., Sewell, A.K.
Deposit date:2017-04-19
Release date:2018-04-25
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:MHC class I antigen
To Be Published
5NQ2
  • Download 5nq2
  • View 5nq2
Molmil generated image of 5nq2
'PORCINE (SUS SCROFA) MAJOR HISTOCOMPATIBILITY COMPLEX, CLASS I, PRESENTING IAYERMCNI
Descriptor:MHC class I antigen, Beta-2-microglobulin, ILE-ALA-TYR-GLU-ARG-MET-CYS-ASN-ILE, ...
Authors:Rizkallah, P.J., Tungatt, K., Sewell, A.K.
Deposit date:2017-04-19
Release date:2018-04-25
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:human T-cell Receptor
To Be Published
5NQ3
  • Download 5nq3
  • View 5nq3
Molmil generated image of 5nq3
'PORCINE (SUS SCROFA) MAJOR HISTOCOMPATIBILITY COMPLEX, CLASS I, WITH HUMAN BETA2 MICRO GLOBULIN, PRESENTING EFEDLTFLA
Descriptor:MHC class I antigen, Beta-2-microglobulin, GLU-PHE-GLU-ASP-LEU-THR-PHE-LEU-ALA, ...
Authors:Rizkallah, P.J., Tungatt, K., Sewell, A.K.
Deposit date:2017-04-19
Release date:2018-04-25
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:human T-cell Receptor
To Be Published
6EQA
  • Download 6eqa
  • View 6eqa
Molmil generated image of 6eqa
HLA CLASS I HISTOCOMPATIBILITY ANTIGEN
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Cole, D.K.
Deposit date:2017-10-12
Release date:2018-10-10
Method:X-RAY DIFFRACTION (3.16 Å)
Cite:HLA class I histocompatibility antigen
To Be Published
6EQB
  • Download 6eqb
  • View 6eqb
Molmil generated image of 6eqb
HLA CLASS I HISTOCOMPATIBILITY ANTIGEN
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Cole, D.K.
Deposit date:2017-10-12
Release date:2018-10-10
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:HLA class I histocompatibility antigen
To Be Published
6G3J
  • Download 6g3j
  • View 6g3j
Molmil generated image of 6g3j
MHC A02 ALLELE PRESENTING MTSAIGILVP
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Sewell, A.K.
Deposit date:2018-03-26
Release date:2019-02-20
Last modified:2019-02-27
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Peptide Super-Agonist Enhances T-Cell Responses to Melanoma
Front Microbiol, 2019
6FR3
  • Download 6fr3
  • View 6fr3
Molmil generated image of 6fr3
003 TCR STUDY OF CDR LOOP FLEXIBILITY
Descriptor:003 TCR Alpha Chain, 003 TCR Beta Chain, 1,2-ETHANEDIOL, ...
Authors:Rizkallah, P.J., Cole, D.K.
Deposit date:2018-02-15
Release date:2018-04-18
Last modified:2018-05-09
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:In Silicoand Structural Analyses Demonstrate That Intrinsic Protein Motions Guide T Cell Receptor Complementarity Determining Region Loop Flexibility.
Front Immunol, 9, 2018
6FR4
  • Download 6fr4
  • View 6fr4
Molmil generated image of 6fr4
003 TCR STUDY OF CDR LOOP FLEXIBILITY
Descriptor:TCR 003 alpha chain, TCR 003 Beta Chain, GLYCEROL, ...
Authors:Rizkallah, P.J., Cole, D.K.
Deposit date:2018-02-15
Release date:2018-04-18
Last modified:2018-05-09
Method:X-RAY DIFFRACTION (1.28 Å)
Cite:In Silicoand Structural Analyses Demonstrate That Intrinsic Protein Motions Guide T Cell Receptor Complementarity Determining Region Loop Flexibility.
Front Immunol, 9, 2018
6FR5
  • Download 6fr5
  • View 6fr5
Molmil generated image of 6fr5
HA1.7 TCR STUDY OF CDR LOOP FLEXIBILITY
Descriptor:TCR HA1.7 specific for FLU epitope PKYVKQNTLKLAT, alpha chain, beta chain, ...
Authors:Rizkallah, P.J., Cole, D.K.
Deposit date:2018-02-15
Release date:2018-04-18
Last modified:2018-05-09
Method:X-RAY DIFFRACTION (1.37 Å)
Cite:In Silicoand Structural Analyses Demonstrate That Intrinsic Protein Motions Guide T Cell Receptor Complementarity Determining Region Loop Flexibility.
Front Immunol, 9, 2018
2BCK
  • Download 2bck
  • View 2bck
Molmil generated image of 2bck
CRYSTAL STRUCTURE OF HLA-A*2402 COMPLEXED WITH A TELOMERASE PEPTIDE
Descriptor:HLA class I histocompatibility antigen, A-24 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Jakobsen, B.K., Cole, D.K., Gao, G.F.
Deposit date:2005-10-19
Release date:2006-01-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of HLA-A*2402 complexed with a telomerase peptide.
Eur.J.Immunol., 36, 2006
2F53
  • Download 2f53
  • View 2f53
Molmil generated image of 2f53
DIRECTED EVOLUTION OF HUMAN T-CELL RECEPTOR CDR2 RESIDUES BY PHAGE DISPLAY DRAMATICALLY ENHANCES AFFINITY FOR COGNATE PEPTIDE-MHC WITHOUT APPARENT CROSS-REACTIVITY
Descriptor:HLA class I histocompatibility antigen, Beta-2-microglobulin, Cancer/testis antigen 1B, ...
Authors:Rizkallah, P.J., Jakobsen, B.K., Dunn, S.M., Sami, M.
Deposit date:2005-11-25
Release date:2006-04-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Directed evolution of human T cell receptor CDR2 residues by phage display dramatically enhances affinity for cognate peptide-MHC without increasing apparent cross-reactivity.
Protein Sci., 15, 2006
2F54
  • Download 2f54
  • View 2f54
Molmil generated image of 2f54
DIRECTED EVOLUTION OF HUMAN T CELL RECEPTOR CDR2 RESIDUES BY PHAGE DISPLAY DRAMATICALLY ENHANCES AFFINITY FOR COGNATE PEPTIDE-MHC WITHOUT INCREASING APPARENT CROSS-REACTIVITY
Descriptor:HLA class I histocompatibility antigen, Beta-2-microglobulin, Cancer/testis antigen 1B, ...
Authors:Rizkallah, P.J., Jakobsen, B.K., Dunn, S.M., Sami, M.
Deposit date:2005-11-25
Release date:2006-04-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Directed evolution of human T cell receptor CDR2 residues by phage display dramatically enhances affinity for cognate peptide-MHC without increasing apparent cross-reactivity.
Protein Sci., 15, 2006
2HP4
  • Download 2hp4
  • View 2hp4
Molmil generated image of 2hp4
COMPUTATIONAL DESIGN AND CRYSTAL STRUCTURE OF AN ENHANCED AFFINITY MUTANT HUMAN CD8-ALPHA-ALPHA CO-RECEPTOR
Descriptor:T-cell surface glycoprotein CD8 alpha chain, SULFATE ION, GLYCEROL
Authors:Rizkallah, P.J., Cole, D.K., Jakobsen, B.K., Boulter, J.M., Glick, M., Gao, G.F.
Deposit date:2006-07-17
Release date:2007-02-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Computational design and crystal structure of an enhanced affinity mutant human CD8 alphaalpha coreceptor
Proteins, 67, 2007
3UTP
  • Download 3utp
  • View 3utp
Molmil generated image of 3utp
1E6 TCR SPECIFIC FOR HLA-A*0201-ALWGPDPAAA
Descriptor:1E6 TCR alpha chain, 1E6 TCR beta chain, GLYCEROL, ...
Authors:Rizkallah, P.J., Cole, D.K., Sewell, A.K., Bulek, A.M.
Deposit date:2011-11-26
Release date:2012-01-25
Last modified:2012-03-07
Method:X-RAY DIFFRACTION (2.574 Å)
Cite:Structural basis for the killing of human beta cells by CD8(+) T cells in type 1 diabetes.
Nat.Immunol., 13, 2012
3UTQ
  • Download 3utq
  • View 3utq
Molmil generated image of 3utq
HUMAN HLA-A*0201-ALWGPDPAAA
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Cole, D.K., Sewell, A.K., Bulek, A.M.
Deposit date:2011-11-26
Release date:2012-01-25
Last modified:2012-03-07
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Structural basis for the killing of human beta cells by CD8(+) T cells in type 1 diabetes.
Nat.Immunol., 13, 2012
3UTS
  • Download 3uts
  • View 3uts
Molmil generated image of 3uts
1E6-A*0201-ALWGPDPAAA COMPLEX, MONOCLINIC
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Cole, D.K., Sewell, A.K., Bulek, A.M.
Deposit date:2011-11-26
Release date:2012-01-25
Last modified:2012-03-07
Method:X-RAY DIFFRACTION (2.712 Å)
Cite:Structural basis for the killing of human beta cells by CD8(+) T cells in type 1 diabetes.
Nat.Immunol., 13, 2012
3UTT
  • Download 3utt
  • View 3utt
Molmil generated image of 3utt
1E6-A*0201-ALWGPDPAAA COMPLEX, TRICLINIC
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Cole, D.K., Sewell, A.K., Bulek, A.M., Rossjohn, J., Gras, S.
Deposit date:2011-11-26
Release date:2012-01-25
Last modified:2012-03-07
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis for the killing of human beta cells by CD8(+) T cells in type 1 diabetes.
Nat.Immunol., 13, 2012
4I4W
  • Download 4i4w
  • View 4i4w
Molmil generated image of 4i4w
PEPTIDE LENGTH DETERMINES THE OUTCOME OF T CELL RECEPTOR/PEPTIDE-MHCI ENGAGEMENT
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Wooldridge, L., Cole, D.K.
Deposit date:2012-11-28
Release date:2013-01-02
Last modified:2015-11-25
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Peptide length determines the outcome of TCR/peptide-MHCI engagement.
Blood, 121, 2013
4JFD
  • Download 4jfd
  • View 4jfd
Molmil generated image of 4jfd
PRESERVATION OF PEPTIDE SPECIFICITY DURING TCR-MHC CONTACT DOMINATED AFFINITY ENHANCEMENT OF A MELANOMA-SPECIFIC TCR
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Cole, D.K., Madura, F., Sewell, A.K.
Deposit date:2013-02-28
Release date:2013-05-29
Last modified:2013-07-17
Method:X-RAY DIFFRACTION (2.46 Å)
Cite:T-cell receptor specificity maintained by altered thermodynamics.
J.Biol.Chem., 288, 2013
4JFE
  • Download 4jfe
  • View 4jfe
Molmil generated image of 4jfe
PRESERVATION OF PEPTIDE SPECIFICITY DURING TCR-MHC CONTACT DOMINATED AFFINITY ENHANCEMENT OF A MELANOMA-SPECIFIC TCR
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Cole, D.K., Madura, F., Sewell, A.K.
Deposit date:2013-02-28
Release date:2013-05-29
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:T-cell receptor specificity maintained by altered thermodynamics.
J.Biol.Chem., 288, 2013
4JFF
  • Download 4jff
  • View 4jff
Molmil generated image of 4jff
PRESERVATION OF PEPTIDE SPECIFICITY DURING TCR-MHC CONTACT DOMINATED AFFINITY ENHANCEMENT OF A MELANOMA-SPECIFIC TCR
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Cole, D.K., Madura, F., Sewell, A.K.
Deposit date:2013-02-28
Release date:2013-05-29
Last modified:2014-04-02
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:T-cell receptor specificity maintained by altered thermodynamics.
J.Biol.Chem., 288, 2013