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3WTZ
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BU of 3wtz by Molmil
Crystal structure of ETS-1 DNA binding and autoinhibitory domains (276-441)
Descriptor: Protein C-ets-1
Authors:Shiina, M, Hamada, K, Ogata, K.
Deposit date:2014-04-21
Release date:2014-08-20
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:A novel allosteric mechanism on protein-DNA interactions underlying the phosphorylation-dependent regulation of Ets1 target gene expressions.
J.Mol.Biol., 427, 2015
3WU0
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Crystal structure of phosphorylated ETS-1 DNA binding and autoinhibitory domains (276-441)
Descriptor: Protein C-ets-1
Authors:Shiina, M, Hamada, K, Ogata, K.
Deposit date:2014-04-21
Release date:2014-08-20
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A novel allosteric mechanism on protein-DNA interactions underlying the phosphorylation-dependent regulation of Ets1 target gene expressions.
J.Mol.Biol., 427, 2015
1E50
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BU of 1e50 by Molmil
AML1/CBFbeta complex
Descriptor: CORE-BINDING FACTOR ALPHA SUBUNIT, CORE-BINDING FACTOR CBF-BETA
Authors:Warren, A.J, Bravo, J, Williams, R.L, Rabbits, T.H.
Deposit date:2000-07-13
Release date:2001-07-12
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Basis for the Heterodimeric Interaction between the Acute Leukaemia-Associated Transcription Factors Aml1 and Cbfbeta
Embo J., 19, 2000
2X47
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BU of 2x47 by Molmil
Crystal structure of human MACROD1
Descriptor: MACRO DOMAIN-CONTAINING PROTEIN 1, SULFATE ION
Authors:Vollmar, M, Phillips, C, Mehrotra, P.V, Ahel, I, Krojer, T, Yue, W, Ugochukwu, E, von Delft, F, Bountra, C, Arrowsmith, C.H, Weigelt, J, Edwards, A, Gileadi, O.
Deposit date:2010-01-28
Release date:2010-03-02
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Identification of Macro Domain Proteins as Novel O-Acetyl-Adp-Ribose Deacetylases.
J.Biol.Chem., 286, 2011
6LH4
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BU of 6lh4 by Molmil
Crystal structural of MacroD1-ADPr complex
Descriptor: ADP-ribose glycohydrolase MACROD1, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE
Authors:Yang, X, Ma, Y, Li, Y.
Deposit date:2019-12-06
Release date:2020-12-09
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.999 Å)
Cite:Molecular basis for the MacroD1-mediated hydrolysis of ADP-ribosylation.
DNA Repair (Amst), 94, 2020
3RI4
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BU of 3ri4 by Molmil
Ets1 cooperative binding to widely separated sites on promoter DNA
Descriptor: Isoform Ets-1 p27 of Protein C-ets-1, TCR alpha promoter DNA
Authors:Babayeva, N.D, Mino, K, Tahirov, T.H.
Deposit date:2011-04-12
Release date:2012-04-04
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis of ets1 cooperative binding to widely separated sites on promoter DNA.
Plos One, 7, 2012
2PP4
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BU of 2pp4 by Molmil
Solution Structure of ETO-TAFH refined in explicit solvent
Descriptor: Protein ETO
Authors:Wei, Y, Liu, S, Lausen, J, Woodrell, C, Cho, S, Biris, N, Kobayashi, N, Yokoyama, S, Werner, M.H.
Deposit date:2007-04-27
Release date:2007-06-19
Last modified:2021-10-20
Method:SOLUTION NMR
Cite:A TAF4-homology domain from the corepressor ETO is a docking platform for positive and negative regulators of transcription
Nat.Struct.Mol.Biol., 14, 2007
2RRC
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BU of 2rrc by Molmil
Solution Structure of RNA aptamer against AML1 Runt domain
Descriptor: 5'-R(P*GP*GP*AP*CP*CP*CP*(AP7)P*CP*CP*AP*CP*GP*GP*CP*GP*AP*GP*GP*UP*CP*CP*A)-3'
Authors:Nomura, Y, Fujiwara, K, Chiba, M, Fukunaga, J, Tanaka, Y, Iibuchi, H, Tanaka, T, Nakamura, Y, Kawai, G, Kozu, T, Sakamoto, T.
Deposit date:2010-06-23
Release date:2011-06-29
Last modified:2020-02-26
Method:SOLUTION NMR
Cite:A novel high affinity RNA motif that mimics DNA in AML1 Runt domain binding
To be Published
1MD0
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CRYSTAL STRUCTURE OF AN INHIBITED FRAGMENT OF Ets-1
Descriptor: C-ets-1 protein
Authors:Garvie, C.W, Pufall, M.A, Graves, B.J, Wolberger, C.
Deposit date:2002-08-06
Release date:2002-12-11
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Analysis of the Autoinhibition of Ets-1 and Its Role in Protein Partnerships
J.Biol.Chem., 277, 2002
1MDM
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INHIBITED FRAGMENT OF ETS-1 AND PAIRED DOMAIN OF PAX5 BOUND TO DNA
Descriptor: C-ETS-1 PROTEIN, PAIRED BOX PROTEIN PAX-5, PAX5/ETS BINDING SITE ON THE MB-1 PROMOTER
Authors:Garvie, C.W, Pufall, M.A, Graves, B.J, Wolberger, C.
Deposit date:2002-08-07
Release date:2002-12-11
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:STRUCTURAL ANALYSIS OF THE AUTOINHIBITION OF ETS-1 AND ITS ROLE IN PROTEIN PARTNERSHIPS
J.Biol.Chem., 277, 2002
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