1E50

AML1/CBFbeta complex

Summary for 1E50

• Entry DOI: 10.2210/pdb1e50/pdb
• Descriptor: CORE-BINDING FACTOR ALPHA SUBUNIT, CORE-BINDING FACTOR CBF-BETA (3 entities in total)
• Functional Keywords: transcription factor, transcription
• Biological source: HOMO SAPIENS (HUMAN); More
• Cellular location: Nucleus: Q01196 Q13951
• Total number of polymer chains: 10
• Total formula weight: 152717.52

Authors

Warren, A.J.,Bravo, J.,Williams, R.L.,Rabbits, T.H. (deposition date: 2000-07-13, release date: 2001-07-12, Last modification date: 2018-01-24)

• Primary citation: Warren, A.J.,Bravo, J.,Williams, R.L.,Rabbits, T.H.; Structural Basis for the Heterodimeric Interaction between the Acute Leukaemia-Associated Transcription Factors Aml1 and Cbfbeta; Embo J., 19:3004-, 2000; PubMed: 10856244; DOI: 10.1093/EMBOJ/19.12.3004

Experimental method

X-RAY DIFFRACTION (2.6 Å)