PDB: 43 resultsInfo pagesStatus searchChemie searchBIRD

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7Q6C	complement C6 FIM1-2 bound to CP010 antibody Descriptor: ACETATE ION, CP010 heavy chain, CP010 light chain, ... Authors: Olesen, H.G, Andersen, G.R. Deposit date: 2021-11-06 Release date: 2022-05-25 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.29274 Å) Cite: Development, Characterization, and in vivo Validation of a Humanized C6 Monoclonal Antibody that Inhibits the Membrane Attack Complex. J Innate Immun, 2022
2N17	NMR structure of a Kazal-type serine protease inhibitor from the subterranean termite defense gland of Coptotermes formosanus Shiraki soldiers Descriptor: Lysozyme-Protease Inhibitor Protein Authors: Negulescu, H, Guo, Y, Garner, T.P, Goodwin, O.Y, Henderson, G, Laine, R.A, Macnaughtan, M.A. Deposit date: 2015-03-23 Release date: 2015-05-06 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: A Kazal-Type Serine Protease Inhibitor from the Defense Gland Secretion of the Subterranean Termite Coptotermes formosanus Shiraki. Plos One, 10, 2015
3PIS	Crystal Structure of Carcinoscorpius rotundicauda Serine Protease Inhibitor Domain 1 Descriptor: Kazal-type serine protease inhibitor SPI-1 Authors: Giri, P.K, Tang, X.H, Sivaraman, J. Deposit date: 2010-11-08 Release date: 2010-12-08 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2 Å) Cite: Modifying the Substrate Specificity of Carcinoscorpius rotundicauda Serine Protease Inhibitor Domain 1 to Target Thrombin To be Published
6JZA	Structure of Fstl1 Descriptor: Follistatin-related protein 1 Authors: Liu, X, Ning, W. Deposit date: 2019-04-30 Release date: 2019-08-21 Last modified: 2019-09-25 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structural and functional study of FK domain of Fstl1. Protein Sci., 28, 2019
7KBU	Structure of Hevin FS-EC Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ... Authors: Machius, M, Fan, S, Rudenko, G. Deposit date: 2020-10-03 Release date: 2021-02-10 Last modified: 2021-07-14 Method: X-RAY DIFFRACTION (2.27 Å) Cite: Interplay between hevin, SPARC, and MDGAs: Modulators of neurexin-neuroligin transsynaptic bridges. Structure, 29, 2021
2KCX	Solution NMR Structure of Kazal-1 Domain of Human Follistatin-related protein 3 (FSTL-3). Northeast Structural Genomics Target HR6186A. Descriptor: Follistatin-related protein 3 Authors: Rossi, P, Chiang, Y, Anderson, S, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) Deposit date: 2008-12-30 Release date: 2009-03-10 Last modified: 2022-03-16 Method: SOLUTION NMR Cite: Solution NMR Structure of Kazal-1 Domain of Human Follistatin-related protein 3 (FSTL-3). Northeast Structural Genomics Target HR6186A. To be Published
1LR7	Crystal structure of Fs1, the heparin-binding domain of follistatin, complexed with the heparin analogue sucrose octasulphate (SOS) Descriptor: SULFATE ION, follistatin Authors: Innis, C.A, Hyvonen, M. Deposit date: 2002-05-15 Release date: 2003-07-29 Last modified: 2022-12-21 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Crystal Structures of the Heparan Sulfate-binding Domain of Follistatin: Insights into ligand binding. J.Biol.Chem., 278, 2003
1LR9	STRUCTURE OF Fs1, THE HEPARIN-BINDING DOMAIN OF FOLLISTATIN Descriptor: Follistatin Authors: Innis, C.A, Hyvonen, M. Deposit date: 2002-05-15 Release date: 2003-07-29 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Crystal Structures of the Heparan Sulfate-binding Domain of Follistatin: Insights into ligand binding. J.Biol.Chem., 278, 2003
1LR8	Crystal structure of Fs1, the heparin-binding domain of follistatin, complexed with the heparin analogue D-myo-inositol hexasulphate (Ins6S) Descriptor: D-MYO-INOSITOL-HEXASULPHATE, Follistatin Authors: Innis, C.A, Hyvonen, M. Deposit date: 2002-05-15 Release date: 2003-07-29 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Crystal Structures of the Heparan Sulfate-binding Domain of Follistatin: Insights into ligand binding. J.Biol.Chem., 278, 2003
8K6L	Cryo-EM structure of human OATP1B1 in complex with DCF Descriptor: 2',7'-bis(chloranyl)-3',6'-bis(oxidanyl)spiro[2-benzofuran-3,9'-xanthene]-1-one, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Shan, Z, Yang, X, Zhang, Y. Deposit date: 2023-07-25 Release date: 2023-09-13 Last modified: 2023-12-20 Method: ELECTRON MICROSCOPY (2.92 Å) Cite: Cryo-EM structures of human organic anion transporting polypeptide OATP1B1. Cell Res., 33, 2023
3TJQ	N-domain of HtrA1 Descriptor: CHLORIDE ION, GLYCEROL, PLATINUM (II) ION, ... Authors: Eigenbrot, C, Ultsch, M. Deposit date: 2011-08-24 Release date: 2012-05-16 Last modified: 2012-06-27 Method: X-RAY DIFFRACTION (2.001 Å) Cite: Structural and Functional Analysis of HtrA1 and Its Subdomains. Structure, 20, 2012
3HH2	Crystal structure of the myostatin:follistatin 288 complex Descriptor: CITRIC ACID, Follistatin, Growth/differentiation factor 8, ... Authors: Cash, J.N, Thompson, T.B. Deposit date: 2009-05-14 Release date: 2009-08-04 Last modified: 2017-11-01 Method: X-RAY DIFFRACTION (2.15 Å) Cite: The structure of myostatin:follistatin 288: insights into receptor utilization and heparin binding Embo J., 28, 2009
5JHW	Crystal Structure of the GDF11:Follistatin 288 complex Descriptor: CITRATE ANION, Follistatin, Growth/differentiation factor 11, ... Authors: Walker, R.G, Thompson, T.B. Deposit date: 2016-04-21 Release date: 2017-03-22 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Structural basis for potency differences between GDF8 and GDF11. BMC Biol., 15, 2017
7EEB	Structure of the CatSpermasome Descriptor: (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Wu, J.P, Ke, M. Deposit date: 2021-03-18 Release date: 2021-07-28 Last modified: 2021-08-11 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: Structure of a mammalian sperm cation channel complex. Nature, 595, 2021
8B0H	2C9, C5b9-CD59 cryoEM structure Descriptor: CD59 glycoprotein, Complement C5, Complement component C6, ... Authors: Couves, E.C, Gardner, S, Bubeck, D. Deposit date: 2022-09-07 Release date: 2023-02-22 Last modified: 2023-03-01 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Structural basis for membrane attack complex inhibition by CD59. Nat Commun, 14, 2023
3B4V	X-Ray structure of Activin in complex with FSTL3 Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Inhibin beta A chain, ... Authors: Thompson, T.B. Deposit date: 2007-10-24 Release date: 2008-09-02 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (2.48 Å) Cite: The structure of FSTL3.activin A complex. Differential binding of N-terminal domains influences follistatin-type antagonist specificity. J.Biol.Chem., 283, 2008
4E0S	Crystal Structure of C5b-6 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Complement C5, ... Authors: Aleshin, A.E, Stec, B, DiScipio, R, Liddington, R.C. Deposit date: 2012-03-05 Release date: 2012-04-18 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (4.21 Å) Cite: Crystal structure of c5b-6 suggests structural basis for priming assembly of the membrane attack complex. J.Biol.Chem., 287, 2012
4A5W	Crystal structure of C5b6 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, COMPLEMENT C5, ... Authors: Hadders, M.A, Bubeck, D, Forneris, F, Pangburn, M, Llorca, O, Lea, S.M, Gros, P. Deposit date: 2011-10-28 Release date: 2012-03-14 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (3.5 Å) Cite: Assembly and Regulation of the Membrane Attack Complex Based on Structures of C5B6 and Sc5B9. Cell Rep., 1, 2012
8B0F	CryoEM structure of C5b8-CD59 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... Authors: Bubeck, D, Couves, E.C, Gardner, S. Deposit date: 2022-09-07 Release date: 2023-02-22 Last modified: 2023-03-01 Method: ELECTRON MICROSCOPY (3 Å) Cite: Structural basis for membrane attack complex inhibition by CD59. Nat Commun, 14, 2023
8B0G	2C9, C5b9-CD59 structure Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CD59 glycoprotein, Complement C5, ... Authors: Couves, E.C, Gardner, S, Bubeck, D. Deposit date: 2022-09-07 Release date: 2023-02-22 Last modified: 2023-03-01 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Structural basis for membrane attack complex inhibition by CD59. Nat Commun, 14, 2023
6H03	OPEN CONFORMATION OF THE MEMBRANE ATTACK COMPLEX Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C5,Complement C5, ... Authors: Menny, A, Serna, M, Boyd, C.M, Gardner, S, Joseph, A.P, Topf, M, Bubeck, D. Deposit date: 2018-07-06 Release date: 2018-12-19 Last modified: 2020-07-29 Method: ELECTRON MICROSCOPY (5.6 Å) Cite: CryoEM reveals how the complement membrane attack complex ruptures lipid bilayers. Nat Commun, 9, 2018
6H04	Closed conformation of the Membrane Attack Complex Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C5,Complement C5, ... Authors: Menny, A, Serna, M, Boyd, C.M, Gardner, S, Joseph, A.P, Topf, M, Bubeck, D. Deposit date: 2018-07-06 Release date: 2018-12-19 Last modified: 2020-07-29 Method: ELECTRON MICROSCOPY (5.6 Å) Cite: CryoEM reveals how the complement membrane attack complex ruptures lipid bilayers. Nat Commun, 9, 2018
7NYC	cryoEM structure of 3C9-sMAC Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... Authors: Menny, A, Couves, E.C, Bubeck, D. Deposit date: 2021-03-22 Release date: 2021-10-06 Last modified: 2021-11-17 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Structural basis of soluble membrane attack complex packaging for clearance. Nat Commun, 12, 2021
7NYD	cryoEM structure of 2C9-sMAC Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... Authors: Menny, A, Couves, E.C, Bubeck, D. Deposit date: 2021-03-22 Release date: 2021-10-06 Last modified: 2021-11-17 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Structural basis of soluble membrane attack complex packaging for clearance. Nat Commun, 12, 2021
1TBQ	CRYSTAL STRUCTURE OF INSECT DERIVED DOUBLE DOMAIN KAZAL INHIBITOR RHODNIIN IN COMPLEX WITH THROMBIN Descriptor: RHODNIIN, THROMBIN Authors: Van De Locht, A, Lamba, D, Bode, W. Deposit date: 1995-03-02 Release date: 1996-10-14 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Two heads are better than one: crystal structure of the insect derived double domain Kazal inhibitor rhodniin in complex with thrombin. EMBO J., 14, 1995

 

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