3HH2
Crystal structure of the myostatin:follistatin 288 complex
Summary for 3HH2
Entry DOI | 10.2210/pdb3hh2/pdb |
Descriptor | Growth/differentiation factor 8, Follistatin, PHOSPHATE ION, ... (5 entities in total) |
Functional Keywords | protein-protein complex, tb domain, cystine knot motif, tgf-beta fold, disulfide linked dimer, follistatin domain (fsd), cleavage on pair of basic residues, cytokine, disulfide bond, glycoprotein, growth factor, secreted, signaling protein-cytokine complex, signaling protein/cytokine |
Biological source | Mus musculus (mouse) More |
Cellular location | Secreted : O08689 P19883 |
Total number of polymer chains | 4 |
Total formula weight | 88698.00 |
Authors | Cash, J.N.,Thompson, T.B. (deposition date: 2009-05-14, release date: 2009-08-04, Last modification date: 2017-11-01) |
Primary citation | Cash, J.N.,Rejon, C.A.,McPherron, A.C.,Bernard, D.J.,Thompson, T.B. The structure of myostatin:follistatin 288: insights into receptor utilization and heparin binding Embo J., 28:2662-2676, 2009 Cited by PubMed: 19644449DOI: 10.1038/emboj.2009.205 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.15 Å) |
Structure validation
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