5JHW

Crystal Structure of the GDF11:Follistatin 288 complex

Summary for 5JHW

• Entry DOI: 10.2210/pdb5jhw/pdb
• Related: 5JI1
• Descriptor: Growth/differentiation factor 11, Follistatin, PHOSPHATE ION, ... (5 entities in total)
• Functional Keywords: gdf11, follistatin, tgfbeta, ligand, cytokine-signaling protein complex, cytokine/signaling protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 89735.64

Authors

Walker, R.G.,Thompson, T.B. (deposition date: 2016-04-21, release date: 2017-03-22, Last modification date: 2023-09-27)

• Primary citation: Walker, R.G.,Czepnik, M.,Goebel, E.J.,McCoy, J.C.,Vujic, A.,Cho, M.,Oh, J.,Aykul, S.,Walton, K.L.,Schang, G.,Bernard, D.J.,Hinck, A.P.,Harrison, C.A.,Martinez-Hackert, E.,Wagers, A.J.,Lee, R.T.,Thompson, T.B.; Structural basis for potency differences between GDF8 and GDF11.; BMC Biol., 15:19-19, 2017; PubMed: 28257634; DOI: 10.1186/s12915-017-0350-1

Experimental method

X-RAY DIFFRACTION (2.35 Å)