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4LNN	B. subtilis glutamine synthetase structures reveal large active site conformational changes and basis for isoenzyme specific regulation: structure of apo form of GS Descriptor: Glutamine synthetase, MAGNESIUM ION, SULFATE ION Authors: Schumacher, M.A, Chinnam, N, Tonthat, N, Fisher, S, Wray, L. Deposit date: 2013-07-11 Release date: 2013-11-13 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Structures of the Bacillus subtilis Glutamine Synthetase Dodecamer Reveal Large Intersubunit Catalytic Conformational Changes Linked to a Unique Feedback Inhibition Mechanism. J.Biol.Chem., 288, 2013
7TFD	P. polymyxa GS(12) - apo Descriptor: Glutamine synthetase, MAGNESIUM ION Authors: Travis, B.A, Peck, J, Schumacher, M.A. Deposit date: 2022-01-06 Release date: 2022-06-29 Last modified: 2024-02-28 Method: ELECTRON MICROSCOPY (3.16 Å) Cite: Molecular dissection of the glutamine synthetase-GlnR nitrogen regulatory circuitry in Gram-positive bacteria. Nat Commun, 13, 2022
6PEW	CryoEM Plasmodium falciparum glutamine synthetase Descriptor: Glutamine synthetase Authors: Ho, C.M, Lai, M, Zhou, Z.H. Deposit date: 2019-06-21 Release date: 2019-12-11 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Bottom-up structural proteomics: cryoEM of protein complexes enriched from the cellular milieu. Nat.Methods, 17, 2020
7V4I	Cryo-EM Structure of Camellia sinensis glutamine synthetase CsGSIb decamer assembly Descriptor: Glutamine synthetase Authors: Xu, W, Chen, Y, Xing, Q, Huang, C. Deposit date: 2021-08-13 Release date: 2022-05-18 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Assembly status transition offers an avenue for activity modulation of a supramolecular enzyme. Elife, 10, 2021
4XYC	NANOMOLAR INHIBITORS OF MYCOBACTERIUM TUBERCULOSIS GLUTAMINE SYNTHETASE 1: SYNTHESIS, BIOLOGICAL EVALUATION AND X-RAY CRYSTALLOGRAPHIC STUDIES Descriptor: 9-phenyl-4H-imidazo[1,2-a]indeno[1,2-e]pyrazin-4-one, Glutamine synthetase 1 Authors: Couturier, C, Silve, S, Morales, R, Ppessegue, B, Llopart, S, Nair, A, Bauer, A, Scheiper, B, poeverlein, c, Ganzhorn, A, Lagrange, S, Bacque, E. Deposit date: 2015-02-02 Release date: 2015-03-25 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Nanomolar inhibitors of Mycobacterium tuberculosis glutamine synthetase 1: Synthesis, biological evaluation and X-ray crystallographic studies. Bioorg.Med.Chem.Lett., 25, 2015
7V4L	Cryo-EM Structure of Camellia sinensis glutamine synthetase CsGSIb inactive Pentamer State III Descriptor: Glutamine synthetase Authors: Xu, W, Chen, Y, Xing, Q, Huang, C. Deposit date: 2021-08-13 Release date: 2022-05-18 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Assembly status transition offers an avenue for activity modulation of a supramolecular enzyme. Elife, 10, 2021
8PVG	Structure of E. coli glutamine synthetase determined by cryoEM at 100 keV Descriptor: Glutamine synthetase Authors: McMullan, G, Naydenova, K, Mihaylov, D, Peet, M.J, Wilson, H, Yamashita, K, Dickerson, J.L, Chen, S, Cannone, G, Lee, Y, Hutchings, K.A, Gittins, O, Sobhy, M, Wells, T, El-Gomati, M.M, Dalby, J, Meffert, M, Schulze-Briese, C, Henderson, R, Russo, C.J. Deposit date: 2023-07-17 Release date: 2023-11-29 Last modified: 2023-12-06 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Structure determination by cryoEM at 100 keV. Proc.Natl.Acad.Sci.USA, 120, 2023
7V4J	Cryo-EM Structure of Camellia sinensis glutamine synthetase CsGSIb inactive Pentamer State I Descriptor: Glutamine synthetase Authors: Xu, W, Chen, Y, Xing, Q, Huang, C. Deposit date: 2021-08-13 Release date: 2022-05-18 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Assembly status transition offers an avenue for activity modulation of a supramolecular enzyme. Elife, 10, 2021
2D3B	Crystal Structure of the Maize Glutamine Synthetase complexed with AMPPNP and Methionine sulfoximine Descriptor: (2S)-2-AMINO-4-(METHYLSULFONIMIDOYL)BUTANOIC ACID, MANGANESE (II) ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... Authors: Unno, H, Uchida, T, Sugawara, H, Kurisu, G, Sugiyama, T, Yamaya, T, Sakakibara, H, Hase, T, Kusunoki, M. Deposit date: 2005-09-26 Release date: 2006-07-18 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (3.5 Å) Cite: Atomic Structure of Plant Glutamine Synthetase: A KEY ENZYME FOR PLANT PRODUCTIVITY J.Biol.Chem., 281, 2006
7TEN	Crystal structure of the Listeria monocytogenes GS-Met-Sox-P- ADP complex to 3.5 Angstrom Descriptor: ADENOSINE-5'-DIPHOSPHATE, Glutamine synthetase, L-METHIONINE-S-SULFOXIMINE PHOSPHATE Authors: Schumacher, M.A. Deposit date: 2022-01-05 Release date: 2022-06-29 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (3.5 Å) Cite: Molecular dissection of the glutamine synthetase-GlnR nitrogen regulatory circuitry in Gram-positive bacteria. Nat Commun, 13, 2022
4S0R	Structure of GS-TnrA complex Descriptor: GLUTAMINE, Glutamine synthetase, MAGNESIUM ION, ... Authors: Schumacher, M.A, Chinnam, N.G, Cuthbert, B, Tonthat, N.K. Deposit date: 2015-01-04 Release date: 2015-03-04 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (3.5 Å) Cite: Structures of regulatory machinery reveal novel molecular mechanisms controlling B. subtilis nitrogen homeostasis. Genes Dev., 29, 2015
2GLS	REFINED ATOMIC MODEL OF GLUTAMINE SYNTHETASE AT 3.5 ANGSTROMS RESOLUTION Descriptor: GLUTAMINE SYNTHETASE, MANGANESE (II) ION Authors: Eisenberg, D, Almassy, R.J, Yamashita, M.M. Deposit date: 1989-05-19 Release date: 1989-10-15 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (3.5 Å) Cite: Refined atomic model of glutamine synthetase at 3.5 A resolution. J.Biol.Chem., 264, 1989
2D3C	Crystal Structure of the Maize Glutamine Synthetase complexed with ADP and Phosphinothricin Phosphate Descriptor: (2S)-2-AMINO-4-[METHYL(PHOSPHONOOXY)PHOSPHORYL]BUTANOIC ACID, ADENOSINE-5'-DIPHOSPHATE, MANGANESE (II) ION, ... Authors: Unno, H, Uchida, T, Sugawara, H, Kurisu, G, Sugiyama, T, Yamaya, T, Sakakibara, H, Hase, T, Kusunoki, M. Deposit date: 2005-09-26 Release date: 2006-07-18 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (3.81 Å) Cite: Atomic Structure of Plant Glutamine Synthetase: A KEY ENZYME FOR PLANT PRODUCTIVITY J.Biol.Chem., 281, 2006
5LDF	Maltose binding protein genetically fused to dodecameric glutamine synthetase Descriptor: Glutamine synthetase, Maltose-binding periplasmic protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose Authors: Coscia, F, Petosa, C, Schoehn, G. Deposit date: 2016-06-25 Release date: 2016-08-10 Last modified: 2024-05-15 Method: ELECTRON MICROSCOPY (6.2 Å) Cite: Fusion to a homo-oligomeric scaffold allows cryo-EM analysis of a small protein. Sci Rep, 6, 2016
8TFC	Cryo-EM structure of Methanosarcina mazie glutamine synthetase captured as partial oligomer Descriptor: Glutamine synthetase Authors: Schumacher, M.A. Deposit date: 2023-07-09 Release date: 2023-11-15 Last modified: 2023-11-29 Method: ELECTRON MICROSCOPY (6.9 Å) Cite: M. mazei glutamine synthetase and glutamine synthetase-GlnK1 structures reveal enzyme regulation by oligomer modulation. Nat Commun, 14, 2023
7V4K	Cryo-EM Structure of Camellia sinensis glutamine synthetase CsGSIb inactive Pentamer State II Descriptor: Glutamine synthetase Authors: Xu, W, Chen, Y, Xing, Q, Huang, C. Deposit date: 2021-08-13 Release date: 2022-05-18 Method: ELECTRON MICROSCOPY Cite: Assembly status transition offers an avenue for activity modulation of a supramolecular enzyme. Elife, 10, 2021

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