1DM3
 
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8BNU
 | | Escherichia coli anaerobic fatty acid beta oxidation trifunctional enzyme (anEcTFE) tetrameric complex | | 分子名称: | 3-ketoacyl-CoA thiolase FadI, Fatty acid oxidation complex subunit alpha | | 著者 | Sah-Teli, S.K, Pinkas, M, Novacek, J, Venkatesan, R. | | 登録日 | 2022-11-14 | | 公開日 | 2023-05-17 | | 最終更新日 | 2023-07-19 | | 実験手法 | ELECTRON MICROSCOPY (3.55 Å) | | 主引用文献 | Structural basis for different membrane-binding properties of E. coli anaerobic and human mitochondrial beta-oxidation trifunctional enzymes.
Structure, 31, 2023
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8BRJ
 | | Escherichia coli anaerobic fatty acid beta oxidation trifunctional enzyme (anEcTFE) trimeric complex | | 分子名称: | 3-ketoacyl-CoA thiolase FadI, Fatty acid oxidation complex subunit alpha | | 著者 | Sah-Teli, S.K, Pinkas, M, Novacek, J, Venkatesan, R. | | 登録日 | 2022-11-23 | | 公開日 | 2023-05-17 | | 最終更新日 | 2023-07-19 | | 実験手法 | ELECTRON MICROSCOPY (4.08 Å) | | 主引用文献 | Structural basis for different membrane-binding properties of E. coli anaerobic and human mitochondrial beta-oxidation trifunctional enzymes.
Structure, 31, 2023
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1M3Z
 | | Biosynthetic thiolase, C89A mutant, complexed with acetyl coenzyme A | | 分子名称: | ACETYL COENZYME *A, Acetyl-CoA acetyltransferase, SULFATE ION | | 著者 | Kursula, P, Ojala, J, Lambeir, A.-M, Wierenga, R.K. | | 登録日 | 2002-07-03 | | 公開日 | 2002-11-29 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | | 主引用文献 | The catalytic cycle of biosynthetic thiolase: A conformational
journey of an acetyl group through four binding modes and two oxyanion holes
Biochemistry, 41, 2002
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1M1T
 | | Biosynthetic thiolase, Q64A mutant | | 分子名称: | Acetyl-CoA acetyltransferase, GLYCEROL, SULFATE ION | | 著者 | Kursula, P, Ojala, J, Lambeir, A.-M, Wierenga, R.K. | | 登録日 | 2002-06-20 | | 公開日 | 2002-11-29 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | The catalytic cycle of biosynthetic thiolase: A conformational
journey of an acetyl group through four binding modes and two oxyanion holes
Biochemistry, 41, 2002
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8BNR
 | | Escherichia coli anaerobic fatty acid beta oxidation trifunctional enzyme (anEcTFE) octameric complex | | 分子名称: | 3-ketoacyl-CoA thiolase FadI, Fatty acid oxidation complex subunit alpha | | 著者 | Sah-Teli, S.K, Pinkas, M, Novacek, J, Venkatesan, R. | | 登録日 | 2022-11-14 | | 公開日 | 2023-05-17 | | 最終更新日 | 2023-11-29 | | 実験手法 | ELECTRON MICROSCOPY (10.3 Å) | | 主引用文献 | Structural basis for different membrane-binding properties of E. coli anaerobic and human mitochondrial beta-oxidation trifunctional enzymes.
Structure, 31, 2023
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1M4S
 | | Biosynthetic thiolase, Cys89 acetylated, unliganded form | | 分子名称: | Acetyl-CoA acetyltransferase, GLYCEROL, SULFATE ION | | 著者 | Kursula, P, Ojala, J, Lambeir, A.-M, Wierenga, R.K. | | 登録日 | 2002-07-03 | | 公開日 | 2002-11-29 | | 最終更新日 | 2018-03-07 | | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | | 主引用文献 | The catalytic cycle of biosynthetic thiolase: A conformational
journey of an acetyl group through four binding modes and two oxyanion holes
Biochemistry, 41, 2002
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5LOT
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5LP7
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6ESQ
 | | Structure of the acetoacetyl-CoA thiolase/HMG-CoA synthase complex from Methanothermococcus thermolithotrophicus soaked with acetyl-CoA | | 分子名称: | CHLORIDE ION, COENZYME A, HydroxyMethylGlutaryl-CoA synthase, ... | | 著者 | Voegeli, B, Engilberge, S, Girard, E, Riobe, F, Maury, O, Erb, J.T, Shima, S, Wagner, T. | | 登録日 | 2017-10-24 | | 公開日 | 2018-03-14 | | 最終更新日 | 2018-04-11 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | Archaeal acetoacetyl-CoA thiolase/HMG-CoA synthase complex channels the intermediate via a fused CoA-binding site.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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1DLV
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7YXM
 | | Benzoylsuccinyl-CoA thiolase with coenzyme A | | 分子名称: | 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Benzoylsuccinyl-CoA thiolase subunit, ... | | 著者 | Ermler, U, Heider, J, Weidenweber, S. | | 登録日 | 2022-02-16 | | 公開日 | 2022-04-06 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Finis tolueni: a new type of thiolase with an integrated Zn-finger subunit catalyzes the final step of anaerobic toluene metabolism.
Febs J., 289, 2022
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6ET9
 | | Structure of the acetoacetyl-CoA-thiolase/HMG-CoA-synthase complex from Methanothermococcus thermolithotrophicus at 2.75 A | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Acetyl-CoA acetyltransferase thiolase, CHLORIDE ION, ... | | 著者 | Engilberge, S, Voegeli, B, Girard, E, Riobe, F, Maury, O, Erb, T.J, Shima, S, Wagner, T. | | 登録日 | 2017-10-25 | | 公開日 | 2018-03-14 | | 最終更新日 | 2018-04-11 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Archaeal acetoacetyl-CoA thiolase/HMG-CoA synthase complex channels the intermediate via a fused CoA-binding site.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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5LNQ
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6HRV
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7YVY
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6DV2
 | | Crystal Structure of Human Mitochondrial Trifunctional Protein | | 分子名称: | Trifunctional enzyme subunit alpha, mitochondrial, Trifunctional enzyme subunit beta | | 著者 | Fu, Z, Xia, C, Battaile, K.P, Kim, J.P. | | 登録日 | 2018-06-22 | | 公開日 | 2018-09-26 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | | 主引用文献 | Crystal structure of human mitochondrial trifunctional protein, a fatty acid beta-oxidation metabolon.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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6HSJ
 | | Crystal structure of the zebrafish peroxisomal SCP2-thiolase (type-1) in complex with CoA | | 分子名称: | ACETATE ION, COENZYME A, GLYCEROL, ... | | 著者 | Wierenga, R.K, Kiema, T.R, Thapa, C.J. | | 登録日 | 2018-10-01 | | 公開日 | 2019-01-02 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.46 Å) | | 主引用文献 | The peroxisomal zebrafish SCP2-thiolase (type-1) is a weak transient dimer as revealed by crystal structures and native mass spectrometry.
Biochem. J., 476, 2019
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7CW5
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6HSP
 | | Crystal structure of the zebrafish peroxisomal SCP2-thiolase (type-1) in complex with CoA and octanoyl-CoA | | 分子名称: | COENZYME A, GLYCEROL, OCTANOYL-COENZYME A, ... | | 著者 | Wierenga, R.K, Kiema, T.R, Thapa, C.J. | | 登録日 | 2018-10-01 | | 公開日 | 2019-01-02 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | | 主引用文献 | The peroxisomal zebrafish SCP2-thiolase (type-1) is a weak transient dimer as revealed by crystal structures and native mass spectrometry.
Biochem. J., 476, 2019
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7FEA
 | | PY14 in complex with Col-D | | 分子名称: | (6~{R},7~{R},9~{E})-6,7-bis(oxidanyl)hexadeca-9,15-dien-11,13-diynoic acid, Acetyl-CoA C-acyltransferase | | 著者 | Lin, C.C, Ko, T.P, Huang, K.F, Yang, Y.L. | | 登録日 | 2021-07-19 | | 公開日 | 2022-07-27 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Integrated omics approach to unveil antifungal bacterial polyynes as acetyl-CoA acetyltransferase inhibitors.
Commun Biol, 5, 2022
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4UBV
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4UBT
 | | Structure of the C93S variant of the 3-ketoacyl-CoA thiolase FadA5 from M. tuberculosis in complex with a steroid and CoA. | | 分子名称: | (2S)-2-[(8S,9S,10R,13S,14S,17R)-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]propanoic acid (non-preferred name), Acetyl-CoA acetyltransferase FadA5, CHLORIDE ION, ... | | 著者 | Schaefer, C.M, Kisker, C. | | 登録日 | 2014-08-13 | | 公開日 | 2014-12-17 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | FadA5 a Thiolase from Mycobacterium tuberculosis: A Steroid-Binding Pocket Reveals the Potential for Drug Development against Tuberculosis.
Structure, 23, 2015
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4UBU
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4UBW
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