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6LU8
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BU of 6lu8 by Molmil
Cryo-EM structure of a human pre-60S ribosomal subunit - state A
Descriptor: 28S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Liang, X, Zuo, M, Zhang, Y, Li, N, Ma, C, Dong, M, Gao, N.
Deposit date:2020-01-26
Release date:2020-08-26
Method:ELECTRON MICROSCOPY (3.13 Å)
Cite:Structural snapshots of human pre-60S ribosomal particles before and after nuclear export.
Nat Commun, 11, 2020
6MTB
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BU of 6mtb by Molmil
Rabbit 80S ribosome with P- and Z-site tRNAs (unrotated state)
Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ...
Authors:Brown, A, Baird, M.R, Yip, M.C.J, Murray, J, Shao, S.
Deposit date:2018-10-19
Release date:2018-11-21
Last modified:2019-05-15
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structures of translationally inactive mammalian ribosomes.
Elife, 7, 2018
6MTC
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BU of 6mtc by Molmil
Rabbit 80S ribosome with Z-site tRNA and IFRD2 (unrotated state)
Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ...
Authors:Brown, A, Baird, M.R, Yip, M.C.J, Murray, J, Shao, S.
Deposit date:2018-10-19
Release date:2018-11-21
Last modified:2019-05-15
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structures of translationally inactive mammalian ribosomes.
Elife, 7, 2018
6MTD
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BU of 6mtd by Molmil
Rabbit 80S ribosome with eEF2 and SERBP1 (unrotated state with 40S head swivel)
Descriptor: 18S rRNA, 28S rRNA, 5.8S rRNA, ...
Authors:Brown, A, Baird, M.R, Yip, M.C.J, Murray, J, Shao, S.
Deposit date:2018-10-19
Release date:2018-11-21
Last modified:2019-05-15
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structures of translationally inactive mammalian ribosomes.
Elife, 7, 2018
6MTE
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BU of 6mte by Molmil
Rabbit 80S ribosome with eEF2 and SERBP1 (rotated state)
Descriptor: 18S rRNA, 28S rRNA, 5.8S rRNA, ...
Authors:Brown, A, Baird, M.R, Yip, M.C.J, Murray, J, Shao, S.
Deposit date:2018-10-19
Release date:2018-11-21
Last modified:2019-05-15
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structures of translationally inactive mammalian ribosomes.
Elife, 7, 2018
6OLE
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BU of 6ole by Molmil
Human ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AP and PE tRNAs
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
Authors:Li, W, Cate, J.H.D.
Deposit date:2019-04-16
Release date:2019-06-19
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule.
Nat.Struct.Mol.Biol., 26, 2019
6OLF
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BU of 6olf by Molmil
Human ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AA and PE tRNAs
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
Authors:Li, W, Cate, J.H.D.
Deposit date:2019-04-16
Release date:2019-06-19
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule.
Nat.Struct.Mol.Biol., 26, 2019
6OLG
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BU of 6olg by Molmil
Human ribosome nascent chain complex stalled by a drug-like small molecule (CDH1_RNC with PP tRNA)
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
Authors:Li, W, Cate, J.H.D.
Deposit date:2019-04-16
Release date:2019-06-19
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule.
Nat.Struct.Mol.Biol., 26, 2019
6OLI
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BU of 6oli by Molmil
Structure of human ribosome nascent chain complex selectively stalled by a drug-like small molecule (USO1-RNC)
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
Authors:Li, W, Cate, J.H.D.
Deposit date:2019-04-16
Release date:2019-06-19
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule.
Nat.Struct.Mol.Biol., 26, 2019
6OLZ
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BU of 6olz by Molmil
Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like molecule with PP tRNA
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
Authors:Li, W, Cate, J.H.D.
Deposit date:2019-04-17
Release date:2019-06-19
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule.
Nat.Struct.Mol.Biol., 26, 2019
6OM0
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BU of 6om0 by Molmil
Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like molecule with AP and PE tRNAs
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
Authors:Li, W, Cate, J.H.D.
Deposit date:2019-04-17
Release date:2019-06-19
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule.
Nat.Struct.Mol.Biol., 26, 2019
6OM7
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BU of 6om7 by Molmil
Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like small molecule with AA and PE tRNAs
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
Authors:Li, W, Cate, J.H.D.
Deposit date:2019-04-18
Release date:2019-06-19
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule.
Nat.Struct.Mol.Biol., 26, 2019
6P5I
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BU of 6p5i by Molmil
Structure of a mammalian 80S ribosome in complex with the Israeli Acute Paralysis Virus IRES (Class 1)
Descriptor: 18S rRNA, 28S rRNA, 5.8S rRNA, ...
Authors:Acosta-Reyes, F.J, Neupane, R, Frank, J, Fernandez, I.S.
Deposit date:2019-05-30
Release date:2019-09-18
Last modified:2020-02-26
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:The Israeli acute paralysis virus IRES captures host ribosomes by mimicking a ribosomal state with hybrid tRNAs.
Embo J., 38, 2019
6P5J
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BU of 6p5j by Molmil
Structure of a mammalian 80S ribosome in complex with the Israeli Acute Paralysis Virus IRES (Class 2)
Descriptor: 18S rRNA, 28S rRNA, 5.8S rRNA, ...
Authors:Acosta-Reyes, F.J, Neupane, R, Frank, J, Fernandez, I.S.
Deposit date:2019-05-30
Release date:2019-09-18
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:The Israeli acute paralysis virus IRES captures host ribosomes by mimicking a ribosomal state with hybrid tRNAs.
Embo J., 38, 2019
6P5K
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BU of 6p5k by Molmil
Structure of a mammalian 80S ribosome in complex with the Israeli Acute Paralysis Virus IRES (Class 3)
Descriptor: 18S rRNA, 28S rRNA, 5.8S rRNA, ...
Authors:Acosta-Reyes, F.J, Neupane, R, Frank, J, Fernandez, I.S.
Deposit date:2019-05-30
Release date:2019-09-18
Last modified:2020-01-08
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:The Israeli acute paralysis virus IRES captures host ribosomes by mimicking a ribosomal state with hybrid tRNAs.
Embo J., 38, 2019
6P5N
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BU of 6p5n by Molmil
Structure of a mammalian 80S ribosome in complex with a single translocated Israeli Acute Paralysis Virus IRES and eRF1
Descriptor: 18S rRNA, 28S rRNA, 5.8S rRNA, ...
Authors:Acosta-Reyes, F.J, Neupane, R, Frank, J, Fernandez, I.S.
Deposit date:2019-05-30
Release date:2019-09-25
Last modified:2020-01-08
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:The Israeli acute paralysis virus IRES captures host ribosomes by mimicking a ribosomal state with hybrid tRNAs.
Embo J., 38, 2019
6QZP
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BU of 6qzp by Molmil
High-resolution cryo-EM structure of the human 80S ribosome
Descriptor: (3beta)-O~3~-[(2R)-2,6-dihydroxy-2-(2-methoxy-2-oxoethyl)-6-methylheptanoyl]cephalotaxine, 18S rRNA (1740-MER), 28S rRNA (3773-MER), ...
Authors:Natchiar, S.K, Myasnikov, A.G, Kratzat, H, Hazemann, I, Klaholz, B.P.
Deposit date:2019-03-12
Release date:2019-04-24
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Visualization of chemical modifications in the human 80S ribosome structure.
Nature, 551, 2017
6R5Q
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BU of 6r5q by Molmil
Structure of XBP1u-paused ribosome nascent chain complex (post-state)
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ...
Authors:Shanmuganathan, V, Cheng, J, Berninghausen, O, Beckmann, R.
Deposit date:2019-03-25
Release date:2019-07-10
Last modified:2019-10-30
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural and mutational analysis of the ribosome-arresting human XBP1u.
Elife, 8, 2019
6R6G
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BU of 6r6g by Molmil
Structure of XBP1u-paused ribosome nascent chain complex with SRP.
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ...
Authors:Shanmuganathan, V, Cheng, J, Braunger, K, Berninghausen, O, Beatrix, B, Beckmann, R.
Deposit date:2019-03-27
Release date:2019-07-10
Last modified:2019-10-30
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural and mutational analysis of the ribosome-arresting human XBP1u.
Elife, 8, 2019
6R6P
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BU of 6r6p by Molmil
Structure of XBP1u-paused ribosome nascent chain complex (rotated state)
Descriptor: 18S rRNA, 28S ribosomal RNA, 40S ribosomal protein S12, ...
Authors:Shanmuganathan, V, Cheng, J, Berninghausen, O, Beckmann, R.
Deposit date:2019-03-27
Release date:2019-07-10
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural and mutational analysis of the ribosome-arresting human XBP1u.
Elife, 8, 2019
6R7Q
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BU of 6r7q by Molmil
Structure of XBP1u-paused ribosome nascent chain complex with Sec61.
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ...
Authors:Shanmuganathan, V, Cheng, J, Braunger, K, Berninghausen, O, Beatrix, B, Beckmann, R.
Deposit date:2019-03-29
Release date:2019-07-10
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural and mutational analysis of the ribosome-arresting human XBP1u.
Elife, 8, 2019
6SGC
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BU of 6sgc by Molmil
Rabbit 80S ribosome stalled on a poly(A) tail
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ...
Authors:Chandrasekaran, V, Juszkiewicz, S, Choi, J, Puglisi, J.D, Brown, A, Shao, S, Ramakrishnan, V, Hegde, R.S.
Deposit date:2019-08-03
Release date:2019-12-04
Last modified:2022-03-30
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Mechanism of ribosome stalling during translation of a poly(A) tail.
Nat.Struct.Mol.Biol., 26, 2019
6SWA
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BU of 6swa by Molmil
Mus musculus brain neocortex ribosome 60S bound to Ebp1
Descriptor: 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Kraushar, M.L, Sprink, T.
Deposit date:2019-09-20
Release date:2020-09-30
Last modified:2021-02-17
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Protein Synthesis in the Developing Neocortex at Near-Atomic Resolution Reveals Ebp1-Mediated Neuronal Proteostasis at the 60S Tunnel Exit.
Mol.Cell, 81, 2021
6T59
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BU of 6t59 by Molmil
Structure of rabbit 80S ribosome translating beta-tubulin in complex with tetratricopeptide protein 5 and nascent chain-associated complex
Descriptor: 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Lin, Z, Gasic, I, Chandrasekaran, V, Peters, N, Shao, S, Ramakrishnan, V, Mitchison, T.J, Hegde, R.S.
Deposit date:2019-10-15
Release date:2019-11-27
Last modified:2020-01-15
Method:ELECTRON MICROSCOPY (3.11 Å)
Cite:TTC5 mediates autoregulation of tubulin via mRNA degradation.
Science, 367, 2020
6W6L
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BU of 6w6l by Molmil
Cryo-EM structure of the human ribosome-TMCO1 translocon
Descriptor: 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Keenan, R.J, McGilvray, P.T.
Deposit date:2020-03-17
Release date:2020-09-02
Method:ELECTRON MICROSCOPY (3.84 Å)
Cite:An ER translocon for multi-pass membrane protein biogenesis.
Elife, 9, 2020

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