3P91
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2IO4
| Crystal structure of PCNA12 dimer from Sulfolobus solfataricus. | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, DNA polymerase sliding clamp B, ... | 著者 | Hlinkova, V, Ling, H. | 登録日 | 2006-10-09 | 公開日 | 2008-04-08 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structures of monomeric, dimeric and trimeric PCNA: PCNA-ring assembly and opening. Acta Crystallogr.,Sect.D, 64, 2008
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3P87
| Structure of human PCNA bound to RNASEH2B PIP box peptide | 分子名称: | Proliferating cell nuclear antigen, Ribonuclease H2 subunit B | 著者 | Bubeck, D, Reijns, M.A, Graham, S.C, Astell, K.R, Jones, E.Y, Jackson, A.P. | 登録日 | 2010-10-13 | 公開日 | 2011-02-02 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.99 Å) | 主引用文献 | PCNA directs type 2 RNase H activity on DNA replication and repair substrates. Nucleic Acids Res., 39, 2011
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3P83
| Structure of the PCNA:RNase HII complex from Archaeoglobus fulgidus. | 分子名称: | DNA polymerase sliding clamp, Ribonuclease HII | 著者 | Bubeck, D, Reijns, M.A, Graham, S.C, Astell, K.R, Jones, E.Y, Jackson, A.P. | 登録日 | 2010-10-13 | 公開日 | 2011-02-02 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | 主引用文献 | PCNA directs type 2 RNase H activity on DNA replication and repair substrates. Nucleic Acids Res., 39, 2011
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2IJX
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3VKX
| Structure of PCNA | 分子名称: | 3,5,3'TRIIODOTHYRONINE, CHLORIDE ION, Proliferating cell nuclear antigen, ... | 著者 | Hashimoto, H, Hishiki, A, Shimizu, T, Sato, M, Punchihewa, C, Connelly, M, Actis, M, Waddell, B, Pagala, V, Fujii, N. | 登録日 | 2011-11-26 | 公開日 | 2012-03-14 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Identification of small molecule proliferating cell nuclear antigen (PCNA) inhibitor that disrupts interactions with PIP-box proteins and inhibits DNA replication J.Biol.Chem., 287, 2012
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2IX2
| Crystal structure of the heterotrimeric PCNA from Sulfolobus solfataricus | 分子名称: | DNA POLYMERASE SLIDING CLAMP A, DNA POLYMERASE SLIDING CLAMP B, DNA POLYMERASE SLIDING CLAMP C | 著者 | Williams, G.J, Johnson, K, McMahon, S.A, Carter, L, Oke, M, Liu, H, Taylor, G.L, White, M.F, Naismith, J.H. | 登録日 | 2006-07-05 | 公開日 | 2006-10-04 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure of the Heterotrimeric PCNA from Sulfolobus Solfataricus. Acta Crystallogr.,Sect.F, 62, 2006
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2IZO
| Structure of an Archaeal PCNA1-PCNA2-FEN1 Complex | 分子名称: | DNA POLYMERASE SLIDING CLAMP B, DNA POLYMERASE SLIDING CLAMP C, FLAP STRUCTURE-SPECIFIC ENDONUCLEASE, ... | 著者 | Dore, A.S, Kilkenny, M.L, Roe, S.M, Pearl, L.H. | 登録日 | 2006-07-25 | 公開日 | 2006-09-06 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structure of an Archaeal PCNA1-PCNA2-Fen1 Complex: Elucidating PCNA Subunit and Client Enzyme Specificity. Nucleic Acids Res., 34, 2006
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3WGW
| Structure of PCNA bound to a small molecule inhibitor | 分子名称: | 4-{4-[(2S)-2-amino-3-hydroxypropyl]-2,6-diiodophenoxy}phenol, Proliferating cell nuclear antigen, SULFATE ION | 著者 | Hashimoto, H. | 登録日 | 2013-08-12 | 公開日 | 2014-02-05 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | A small molecule inhibitor of monoubiquitinated Proliferating Cell Nuclear Antigen (PCNA) inhibits repair of interstrand DNA cross-link, enhances DNA double strand break, and sensitizes cancer cells to cisplatin. J.Biol.Chem., 289, 2014
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6CBI
| PCNA in complex with inhibitor | 分子名称: | GLY-ARG-LYS-ARG-ARG-GLN-DAB-SER-MET-THR-GLU-PHE-TYR-HIS, Proliferating cell nuclear antigen, SULFATE ION | 著者 | Bruning, J.B, Wegener, K.L. | 登録日 | 2018-02-03 | 公開日 | 2018-07-04 | 最終更新日 | 2020-01-29 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Rational Design of a 310-Helical PIP-Box Mimetic Targeting PCNA, the Human Sliding Clamp. Chemistry, 24, 2018
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6CX2
| S177G Mutant of Yeast PCNA | 分子名称: | Proliferating cell nuclear antigen | 著者 | Powers, K.T. | 登録日 | 2018-04-02 | 公開日 | 2018-04-11 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.101 Å) | 主引用文献 | Identification of New Mutations at the PCNA Subunit Interface that Block Translesion Synthesis. PLoS ONE, 11, 2016
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7EP8
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5AUJ
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5CFK
| Crystal structure of Proliferating Cell Nuclear Antigen from Leishmania donovani at 3.2 A resolution | 分子名称: | Proliferating cell nuclear antigen,Proliferating cell nuclear antigen | 著者 | Shukla, P.K, Yadav, S.P, Sharma, P, Kaur, P, Sharma, S, Singh, T.P. | 登録日 | 2015-07-08 | 公開日 | 2015-10-07 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Crystal structure of Proliferating Cell Nuclear Antigen from Leishmania donovani at 3.2 A resolution To Be Published
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5DAI
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5DA7
| monomeric PCNA bound to a small protein inhibitor | 分子名称: | DNA polymerase sliding clamp 1, Proliferating cell nuclear antigen, SULFATE ION, ... | 著者 | Ladner, J.E, Altieri, A.S, Kelman, Z. | 登録日 | 2015-08-19 | 公開日 | 2016-05-11 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.802 Å) | 主引用文献 | A small protein inhibits proliferating cell nuclear antigen by breaking the DNA clamp. Nucleic Acids Res., 44, 2016
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5E0U
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5E0V
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5E0T
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7KQ1
| PCNA bound to truncated peptide mimetic | 分子名称: | LYS-ARG-ARG-GLN-THR-SER-MET-THR-ASP-PHE-TYR-HIS-SER-LYS-ARG, Proliferating cell nuclear antigen | 著者 | Vandborg, B.A, Bruning, J.B. | 登録日 | 2020-11-13 | 公開日 | 2021-05-19 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Unlocking the PIP-box: A peptide library reveals interactions that drive high-affinity binding to human PCNA. J.Biol.Chem., 296, 2021
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7KQ0
| PCNA bound to peptide mimetic | 分子名称: | LYS-ARG-ARG-GLN-THR-SER-MET-THR-ASP-TYR-TYR-HIS-SER-LYS-ARG, Proliferating cell nuclear antigen | 著者 | Vandborg, B.A, Bruning, J.B. | 登録日 | 2020-11-13 | 公開日 | 2021-05-19 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Unlocking the PIP-box: A peptide library reveals interactions that drive high-affinity binding to human PCNA. J.Biol.Chem., 296, 2021
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7M5M
| PCNA bound to peptide mimetic | 分子名称: | N-BUTANE, Peptide mimetic (ACE)RQCSMTCFYHSK(NH2) with linker, Proliferating cell nuclear antigen | 著者 | Vandborg, B.A, Bruning, J.B. | 登録日 | 2021-03-24 | 公開日 | 2021-08-11 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | A cell permeable bimane-constrained PCNA-interacting peptide. Rsc Chem Biol, 2, 2021
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7M5L
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7M5N
| PCNA bound to peptide mimetic with linker | 分子名称: | 1,3-dimethylbenzene, Peptide mimetic (ACE)RQCSMTCFYHSK(NH2) with linker, Proliferating cell nuclear antigen | 著者 | Vandborg, B.A, Bruning, J.B. | 登録日 | 2021-03-24 | 公開日 | 2021-08-11 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.11 Å) | 主引用文献 | A cell permeable bimane-constrained PCNA-interacting peptide. Rsc Chem Biol, 2, 2021
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1U76
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