Loading
PDBj
メニューPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

3P91
DownloadVisualize
BU of 3p91 by Molmil
Crystal structure of Proliferating Cellular Nuclear Antigen from Entamoeba histolytica
分子名称: Proliferating cell nuclear antigen
著者Lara-Gonzalez, S, Cardona-Felix, C.S, Brieba, L.G.
登録日2010-10-15
公開日2011-06-01
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure and biochemical characterization of proliferating cellular nuclear antigen from a parasitic protozoon.
Acta Crystallogr.,Sect.D, 67, 2011
2IO4
DownloadVisualize
BU of 2io4 by Molmil
Crystal structure of PCNA12 dimer from Sulfolobus solfataricus.
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, DNA polymerase sliding clamp B, ...
著者Hlinkova, V, Ling, H.
登録日2006-10-09
公開日2008-04-08
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structures of monomeric, dimeric and trimeric PCNA: PCNA-ring assembly and opening.
Acta Crystallogr.,Sect.D, 64, 2008
3P87
DownloadVisualize
BU of 3p87 by Molmil
Structure of human PCNA bound to RNASEH2B PIP box peptide
分子名称: Proliferating cell nuclear antigen, Ribonuclease H2 subunit B
著者Bubeck, D, Reijns, M.A, Graham, S.C, Astell, K.R, Jones, E.Y, Jackson, A.P.
登録日2010-10-13
公開日2011-02-02
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.99 Å)
主引用文献PCNA directs type 2 RNase H activity on DNA replication and repair substrates.
Nucleic Acids Res., 39, 2011
3P83
DownloadVisualize
BU of 3p83 by Molmil
Structure of the PCNA:RNase HII complex from Archaeoglobus fulgidus.
分子名称: DNA polymerase sliding clamp, Ribonuclease HII
著者Bubeck, D, Reijns, M.A, Graham, S.C, Astell, K.R, Jones, E.Y, Jackson, A.P.
登録日2010-10-13
公開日2011-02-02
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献PCNA directs type 2 RNase H activity on DNA replication and repair substrates.
Nucleic Acids Res., 39, 2011
2IJX
DownloadVisualize
BU of 2ijx by Molmil
Crystal structure of PCNA3 monomer from Sulfolobus solfataricus.
分子名称: 1,2-ETHANEDIOL, DNA polymerase sliding clamp A
著者Hlinkova, V, Ling, H.
登録日2006-10-01
公開日2007-10-16
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structures of monomeric, dimeric and trimeric PCNA: PCNA-ring assembly and opening.
Acta Crystallogr.,Sect.D, 64, 2008
3VKX
DownloadVisualize
BU of 3vkx by Molmil
Structure of PCNA
分子名称: 3,5,3'TRIIODOTHYRONINE, CHLORIDE ION, Proliferating cell nuclear antigen, ...
著者Hashimoto, H, Hishiki, A, Shimizu, T, Sato, M, Punchihewa, C, Connelly, M, Actis, M, Waddell, B, Pagala, V, Fujii, N.
登録日2011-11-26
公開日2012-03-14
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Identification of small molecule proliferating cell nuclear antigen (PCNA) inhibitor that disrupts interactions with PIP-box proteins and inhibits DNA replication
J.Biol.Chem., 287, 2012
2IX2
DownloadVisualize
BU of 2ix2 by Molmil
Crystal structure of the heterotrimeric PCNA from Sulfolobus solfataricus
分子名称: DNA POLYMERASE SLIDING CLAMP A, DNA POLYMERASE SLIDING CLAMP B, DNA POLYMERASE SLIDING CLAMP C
著者Williams, G.J, Johnson, K, McMahon, S.A, Carter, L, Oke, M, Liu, H, Taylor, G.L, White, M.F, Naismith, J.H.
登録日2006-07-05
公開日2006-10-04
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of the Heterotrimeric PCNA from Sulfolobus Solfataricus.
Acta Crystallogr.,Sect.F, 62, 2006
2IZO
DownloadVisualize
BU of 2izo by Molmil
Structure of an Archaeal PCNA1-PCNA2-FEN1 Complex
分子名称: DNA POLYMERASE SLIDING CLAMP B, DNA POLYMERASE SLIDING CLAMP C, FLAP STRUCTURE-SPECIFIC ENDONUCLEASE, ...
著者Dore, A.S, Kilkenny, M.L, Roe, S.M, Pearl, L.H.
登録日2006-07-25
公開日2006-09-06
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structure of an Archaeal PCNA1-PCNA2-Fen1 Complex: Elucidating PCNA Subunit and Client Enzyme Specificity.
Nucleic Acids Res., 34, 2006
3WGW
DownloadVisualize
BU of 3wgw by Molmil
Structure of PCNA bound to a small molecule inhibitor
分子名称: 4-{4-[(2S)-2-amino-3-hydroxypropyl]-2,6-diiodophenoxy}phenol, Proliferating cell nuclear antigen, SULFATE ION
著者Hashimoto, H.
登録日2013-08-12
公開日2014-02-05
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A small molecule inhibitor of monoubiquitinated Proliferating Cell Nuclear Antigen (PCNA) inhibits repair of interstrand DNA cross-link, enhances DNA double strand break, and sensitizes cancer cells to cisplatin.
J.Biol.Chem., 289, 2014
6CBI
DownloadVisualize
BU of 6cbi by Molmil
PCNA in complex with inhibitor
分子名称: GLY-ARG-LYS-ARG-ARG-GLN-DAB-SER-MET-THR-GLU-PHE-TYR-HIS, Proliferating cell nuclear antigen, SULFATE ION
著者Bruning, J.B, Wegener, K.L.
登録日2018-02-03
公開日2018-07-04
最終更新日2020-01-29
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Rational Design of a 310-Helical PIP-Box Mimetic Targeting PCNA, the Human Sliding Clamp.
Chemistry, 24, 2018
6CX2
DownloadVisualize
BU of 6cx2 by Molmil
S177G Mutant of Yeast PCNA
分子名称: Proliferating cell nuclear antigen
著者Powers, K.T.
登録日2018-04-02
公開日2018-04-11
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.101 Å)
主引用文献Identification of New Mutations at the PCNA Subunit Interface that Block Translesion Synthesis.
PLoS ONE, 11, 2016
7EP8
DownloadVisualize
BU of 7ep8 by Molmil
Crystal structure of PCNA from Neurospora crassa
分子名称: Proliferating cell nuclear antigen
著者Sundaram, R, Vasudevan, D.
登録日2021-04-26
公開日2021-06-30
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Interdomain connecting loop and J loop structures determine cross-species compatibility of PCNA.
J.Biol.Chem., 297, 2021
5AUJ
DownloadVisualize
BU of 5auj by Molmil
Pyrococcus furiosus proliferating cell nuclear antigen (PCNA) SeMet derivative
分子名称: DNA polymerase sliding clamp
著者Watanabe, Y, Oyama, T.
登録日2015-04-21
公開日2016-04-27
最終更新日2020-02-19
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Pyrococcus furiosus proliferating cell nuclear antigen (PCNA) SeMet derivative
To Be Published
5CFK
DownloadVisualize
BU of 5cfk by Molmil
Crystal structure of Proliferating Cell Nuclear Antigen from Leishmania donovani at 3.2 A resolution
分子名称: Proliferating cell nuclear antigen,Proliferating cell nuclear antigen
著者Shukla, P.K, Yadav, S.P, Sharma, P, Kaur, P, Sharma, S, Singh, T.P.
登録日2015-07-08
公開日2015-10-07
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Crystal structure of Proliferating Cell Nuclear Antigen from Leishmania donovani at 3.2 A resolution
To Be Published
5DAI
DownloadVisualize
BU of 5dai by Molmil
Proliferating cell nuclear antigen homolog 1 bound to FEN-1 peptide
分子名称: C-terminus of FEN-1 protein, DNA polymerase sliding clamp 1, SULFATE ION
著者Ladner, J.E, Altieri, A.S, Kelman, Z.
登録日2015-08-20
公開日2016-05-11
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A small protein inhibits proliferating cell nuclear antigen by breaking the DNA clamp.
Nucleic Acids Res., 44, 2016
5DA7
DownloadVisualize
BU of 5da7 by Molmil
monomeric PCNA bound to a small protein inhibitor
分子名称: DNA polymerase sliding clamp 1, Proliferating cell nuclear antigen, SULFATE ION, ...
著者Ladner, J.E, Altieri, A.S, Kelman, Z.
登録日2015-08-19
公開日2016-05-11
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.802 Å)
主引用文献A small protein inhibits proliferating cell nuclear antigen by breaking the DNA clamp.
Nucleic Acids Res., 44, 2016
5E0U
DownloadVisualize
BU of 5e0u by Molmil
Human PCNA variant (S228I) complexed with p21 at 1.9 Angstroms
分子名称: Cyclin-dependent kinase inhibitor 1, Proliferating cell nuclear antigen
著者Duffy, C.M, Hilbert, B.J, Kelch, B.A.
登録日2015-09-29
公開日2016-04-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献A Disease-Causing Variant in PCNA Disrupts a Promiscuous Protein Binding Site.
J.Mol.Biol., 428, 2016
5E0V
DownloadVisualize
BU of 5e0v by Molmil
Human PCNA variant (S228I) complexed with FEN1 at 2.1 Angstroms
分子名称: Flap endonuclease 1, Proliferating cell nuclear antigen
著者Duffy, C.M, Hilbert, B.J, Kelch, B.A.
登録日2015-09-29
公開日2016-04-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.074 Å)
主引用文献A Disease-Causing Variant in PCNA Disrupts a Promiscuous Protein Binding Site.
J.Mol.Biol., 428, 2016
5E0T
DownloadVisualize
BU of 5e0t by Molmil
Human PCNA mutant - S228I
分子名称: Proliferating cell nuclear antigen
著者Duffy, C.M, Hilbert, B.J, Kelch, B.A.
登録日2015-09-29
公開日2016-04-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.6653 Å)
主引用文献A Disease-Causing Variant in PCNA Disrupts a Promiscuous Protein Binding Site.
J.Mol.Biol., 428, 2016
7KQ1
DownloadVisualize
BU of 7kq1 by Molmil
PCNA bound to truncated peptide mimetic
分子名称: LYS-ARG-ARG-GLN-THR-SER-MET-THR-ASP-PHE-TYR-HIS-SER-LYS-ARG, Proliferating cell nuclear antigen
著者Vandborg, B.A, Bruning, J.B.
登録日2020-11-13
公開日2021-05-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Unlocking the PIP-box: A peptide library reveals interactions that drive high-affinity binding to human PCNA.
J.Biol.Chem., 296, 2021
7KQ0
DownloadVisualize
BU of 7kq0 by Molmil
PCNA bound to peptide mimetic
分子名称: LYS-ARG-ARG-GLN-THR-SER-MET-THR-ASP-TYR-TYR-HIS-SER-LYS-ARG, Proliferating cell nuclear antigen
著者Vandborg, B.A, Bruning, J.B.
登録日2020-11-13
公開日2021-05-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Unlocking the PIP-box: A peptide library reveals interactions that drive high-affinity binding to human PCNA.
J.Biol.Chem., 296, 2021
7M5M
DownloadVisualize
BU of 7m5m by Molmil
PCNA bound to peptide mimetic
分子名称: N-BUTANE, Peptide mimetic (ACE)RQCSMTCFYHSK(NH2) with linker, Proliferating cell nuclear antigen
著者Vandborg, B.A, Bruning, J.B.
登録日2021-03-24
公開日2021-08-11
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献A cell permeable bimane-constrained PCNA-interacting peptide.
Rsc Chem Biol, 2, 2021
7M5L
DownloadVisualize
BU of 7m5l by Molmil
PCNA bound to peptide mimetic with linker
分子名称: PROPANE, Peptide mimetic (ACE)RQCSMTCFYHSK(NH2) with linker, Proliferating cell nuclear antigen
著者Vandborg, B.A, Bruning, J.B.
登録日2021-03-24
公開日2021-08-11
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献A cell permeable bimane-constrained PCNA-interacting peptide.
Rsc Chem Biol, 2, 2021
7M5N
DownloadVisualize
BU of 7m5n by Molmil
PCNA bound to peptide mimetic with linker
分子名称: 1,3-dimethylbenzene, Peptide mimetic (ACE)RQCSMTCFYHSK(NH2) with linker, Proliferating cell nuclear antigen
著者Vandborg, B.A, Bruning, J.B.
登録日2021-03-24
公開日2021-08-11
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.11 Å)
主引用文献A cell permeable bimane-constrained PCNA-interacting peptide.
Rsc Chem Biol, 2, 2021
1U76
DownloadVisualize
BU of 1u76 by Molmil
Crystal structure of hPCNA bound to residues 452-466 of the DNA polymerase-delta-p66 subunit
分子名称: KANRQVSITGFFQRK peptide from DNA polymerase delta subunit 3, Proliferating cell nuclear antigen
著者Bruning, J.B, Shamoo, Y.
登録日2004-08-02
公開日2004-12-14
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural and Thermodynamic Analysis of Human PCNA with Peptides Derived from DNA Polymerase-delta p66 Subunit and Flap Endonuclease-1.
Structure, 12, 2004

218853

件を2024-04-24に公開中

PDB statisticsPDBj update infoContact PDBjnumon