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5HED
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BU of 5hed by Molmil
The third PDZ domain from the synaptic protein PSD-95 in complex with a mutant C-terminal peptide derived from CRIPT (T-2F)
Descriptor: Cysteine-rich PDZ-binding protein, Disks large homolog 4
Authors:White, K.I, Raman, A.S, Ranganathan, R.
Deposit date:2016-01-05
Release date:2016-11-16
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Origins of Allostery and Evolvability in Proteins: A Case Study.
Cell(Cambridge,Mass.), 166, 2016
5FB8
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BU of 5fb8 by Molmil
Structure of Interleukin-16 bound to the 14.1 antibody
Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Anti-IL-16 antibody 14.1 Fab domain Heavy Chain, ...
Authors:Hall, G, Cowan, R, Bayliss, R, Carr, M.
Deposit date:2015-12-14
Release date:2016-06-08
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Structure of a Potential Therapeutic Antibody Bound to Interleukin-16 (IL-16): MECHANISTIC INSIGHTS AND NEW THERAPEUTIC OPPORTUNITIES.
J.Biol.Chem., 291, 2016
5F67
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BU of 5f67 by Molmil
An exquisitely specific PDZ/target recognition revealed by the structure of INAD PDZ3 in complex with TRP channel tail
Descriptor: Inactivation-no-after-potential D protein, TRP C terminal Tail
Authors:Ye, F, Shang, Y, Liu, W, Zhang, M.
Deposit date:2015-12-05
Release date:2016-02-24
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:An Exquisitely Specific PDZ/Target Recognition Revealed by the Structure of INAD PDZ3 in Complex with TRP Channel Tail
Structure, 24, 2016
5F3X
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BU of 5f3x by Molmil
Crystal structure of Harmonin NPDZ1 in complex with ANKS4B SAM-PBM
Descriptor: Ankyrin repeat and SAM domain-containing protein 4B, CHLORIDE ION, Harmonin
Authors:Li, J, He, Y, Lu, Q, Zhang, M.
Deposit date:2015-12-03
Release date:2016-03-16
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.649 Å)
Cite:Mechanistic Basis of Organization of the Harmonin/USH1C-Mediated Brush Border Microvilli Tip-Link Complex
Dev.Cell, 36, 2016
5EYZ
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BU of 5eyz by Molmil
CRYSTAL STRUCTURE OF THE PTPN4 PDZ DOMAIN COMPLEXED WITH THE TAILORED PEPTIDE CYTO8-RETEV
Descriptor: CHLORIDE ION, CYTO8-RETEV, Tyrosine-protein phosphatase non-receptor type 4
Authors:Maisonneuve, P, Vaney, M.C, Babault, B, Caillet-Saguy, C, Lafon, M, Delepierre, M, Cordier, F, Wolff, N.
Deposit date:2015-11-26
Release date:2016-06-08
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Molecular Basis of the Interaction of the Human Protein Tyrosine Phosphatase Non-receptor Type 4 (PTPN4) with the Mitogen-activated Protein Kinase p38 gamma.
J.Biol.Chem., 291, 2016
5EZ0
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BU of 5ez0 by Molmil
CRYSTAL STRUCTURE OF THE PTPN4 PDZ DOMAIN COMPLEXED WITH THE PDZ BINDING MOTIF OF THE MITOGEN ACTIVATED PROTEIN KINASE P38GAMMA.
Descriptor: Mitogen-activated protein kinase 12, SULFATE ION, Tyrosine-protein phosphatase non-receptor type 4
Authors:Maisonneuve, P, Vaney, M.C, Caillet-Saguy, C, Lafon, M, Delepierre, M, Cordier, F, Wolff, N.
Deposit date:2015-11-26
Release date:2016-06-08
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Molecular Basis of the Interaction of the Human Protein Tyrosine Phosphatase Non-receptor Type 4 (PTPN4) with the Mitogen-activated Protein Kinase p38 gamma.
J.Biol.Chem., 291, 2016
5EM9
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BU of 5em9 by Molmil
Crystal structure of the SNX27 PDZ domain bound to the phosphorylated C-terminal 5HT4(a)R PDZ binding motif
Descriptor: SEP-LEU-GLU-SER-CYS-PHE, Sorting nexin-27
Authors:Collins, B.M, Clairfeuille, T.
Deposit date:2015-11-06
Release date:2016-09-07
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:A molecular code for endosomal recycling of phosphorylated cargos by the SNX27-retromer complex.
Nat.Struct.Mol.Biol., 23, 2016
5EMB
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BU of 5emb by Molmil
Crystal structure of the SNX27 PDZ domain bound to the C-terminal phosphorylated PTHR PDZ binding motif
Descriptor: GLU-GLU-TRP-SEP-THR-VAL-MET, Sorting nexin-27
Authors:Collins, B.M, Clairfeuille, T.
Deposit date:2015-11-06
Release date:2016-09-07
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (0.85 Å)
Cite:A molecular code for endosomal recycling of phosphorylated cargos by the SNX27-retromer complex.
Nat.Struct.Mol.Biol., 23, 2016
5EMA
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BU of 5ema by Molmil
Crystal structure of the SNX27 PDZ domain bound to the phosphorylated C-terminal LRRC3B PDZ binding motif
Descriptor: ASP-ASP-ILE-SEP-THR-VAL-VAL, GLYCEROL, Sorting nexin-27
Authors:Collins, B.M, Clairfeuille, T.
Deposit date:2015-11-06
Release date:2016-09-07
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.32 Å)
Cite:A molecular code for endosomal recycling of phosphorylated cargos by the SNX27-retromer complex.
Nat.Struct.Mol.Biol., 23, 2016
5ELQ
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BU of 5elq by Molmil
Crystal structure of the SNX27 PDZ domain bound to the C-terminal DGKzeta PDZ binding motif
Descriptor: GLU-ASP-GLN-GLU-THR-ALA-VAL, Sorting nexin-27, TETRAETHYLENE GLYCOL
Authors:Collins, B.M, Clairfeuille, T.
Deposit date:2015-11-05
Release date:2016-09-07
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:A molecular code for endosomal recycling of phosphorylated cargos by the SNX27-retromer complex.
Nat.Struct.Mol.Biol., 23, 2016
5E6P
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BU of 5e6p by Molmil
PlexinB2 cytoplasmic region/PDZ-RhoGEF PDZ domain complex
Descriptor: Plexin-B2, Rho guanine nucleotide exchange factor 11
Authors:Pascoe, H.G, Zhang, X.
Deposit date:2015-10-10
Release date:2015-11-18
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.215 Å)
Cite:Secondary PDZ domain-binding site on class B plexins enhances the affinity for PDZ-RhoGEF.
Proc.Natl.Acad.Sci.USA, 112, 2015
5E21
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BU of 5e21 by Molmil
PDZ2 of LNX2 at 277K,single conformer model
Descriptor: Ligand of Numb protein X 2
Authors:Hekstra, D.R, White, K.I, Socolich, M.A, Ranganathan, R.
Deposit date:2015-09-30
Release date:2016-12-07
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.011 Å)
Cite:Electric-field-stimulated protein mechanics.
Nature, 540, 2016
5E22
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BU of 5e22 by Molmil
The second PDZ domain of Ligand of Numb protein X 2 in the presence of an electric field of ~1 MV/cm along the crystallographic x axis, with eightfold extrapolation of structure factor differences.
Descriptor: GLYCEROL, Ligand of Numb protein X 2
Authors:Hekstra, D.R, White, K.I, Socolich, M.A, Henning, R.W, Srajer, V, Ranganathan, R.
Deposit date:2015-09-30
Release date:2016-12-07
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.797 Å)
Cite:Electric-field-stimulated protein mechanics.
Nature, 540, 2016
5E1Y
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BU of 5e1y by Molmil
PDZ2 of LNX2 at 277K, model with alternate conformations
Descriptor: Ligand of Numb protein X 2
Authors:Hekstra, D.R, White, K.I, Socolich, M.A, Ranganathan, R.
Deposit date:2015-09-30
Release date:2016-12-07
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.011 Å)
Cite:Electric-field-stimulated protein mechanics.
Nature, 540, 2016
5E11
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BU of 5e11 by Molmil
Second PDZ domain of Ligand of Numb protein X 2 by Laue crystallography (no electric field)
Descriptor: Ligand of Numb protein X 2
Authors:Hekstra, D.R, White, K.I, Socolich, M.A, Henning, R.W, Srajer, V, Ranganathan, R.
Deposit date:2015-09-29
Release date:2016-12-07
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Electric-field-stimulated protein mechanics.
Nature, 540, 2016
5DTH
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BU of 5dth by Molmil
Crystal structure of MUPP1 PDZ8 domain from rattus norvegicus
Descriptor: Multiple PDZ domain protein
Authors:Li, J, Lv, Y, Zhu, H, Liu, W.
Deposit date:2015-09-18
Release date:2016-09-14
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structure and biochemical characteristics of MUPP1 PDZ8 domain from rattus norregicus
To Be Published
5D13
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BU of 5d13 by Molmil
Third PDZ domain (PDZ3) of PSD-95 complexed with CFMOC-KKETEV peptide
Descriptor: CFMOC-KKETEV peptide, Disks large homolog 4
Authors:De, S, Spaller, M.R, Olson, R.
Deposit date:2015-08-03
Release date:2016-08-17
Last modified:2024-04-24
Method:X-RAY DIFFRACTION (2.151 Å)
Cite:Chemically-modified peptides as inhibitors of PDZ3 of PSD-95
to be published
5A2P
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BU of 5a2p by Molmil
THE COMPLEX STRUCTURE OF PDZ DOMAINS IN SYNTENIN-1 WITH 4L PEPTIDE
Descriptor: SYNDECAN-4, SYNTENIN-1
Authors:Yoo, J.H, Yun, J.H, Cho, H.S, Lee, W.
Deposit date:2015-05-21
Release date:2016-06-01
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.496 Å)
Cite:Titl the Complex Structure of Pdz Domains in Syntenin-1 with 4L Peptide
To be Published
4Z8J
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BU of 4z8j by Molmil
Crystal structure of the SNX27 PDZ domain bound to the C-terminal PTHR PDZ binding motif
Descriptor: C-terminal PDZ binding motif from parathyroid hormone receptor (PTHR), Sorting nexin-27
Authors:Clairfeuille, T, Pavlos, N, Collins, B.M.
Deposit date:2015-04-09
Release date:2016-02-24
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (0.95 Å)
Cite:Role of SNX27-retromer in PTHR trafficking
To Be Published
4Z33
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BU of 4z33 by Molmil
Crystal structure of the syntenin PDZ1 and PDZ2 tandem in complex with the Frizzled 7 C-terminal fragment and PIP2
Descriptor: ACETATE ION, D-MYO-INOSITOL-4,5-BISPHOSPHATE, GLYCEROL, ...
Authors:Egea-Jimenez, A.L, Gallardo, R, Garcia-Pino, A, Ivarsson, Y, Wawrzyniak, A.M, Kashyap, R, Loris, R, Schymkowitz, J, Rousseau, F, Zimmermann, P.
Deposit date:2015-03-30
Release date:2016-06-29
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Crystal structure of the syntenin PDZ1 and PDZ2 tandem in complex with the Frizzled 7 C-terminal fragment and PIP2
To Be Published
4YYX
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BU of 4yyx by Molmil
Crystal structure of the ZO-1 PDZ1 domain in complex with the 7-mer Claudin2 C-terminal tail
Descriptor: FORMIC ACID, Tight junction protein ZO-1 fused with Claudin-2 C-terminal
Authors:Nomme, J, Lavie, A.
Deposit date:2015-03-24
Release date:2015-04-01
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Structural Basis of a Key Factor Regulating the Affinity between the Zonula Occludens First PDZ Domain and Claudins.
J.Biol.Chem., 290, 2015
4YDP
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BU of 4ydp by Molmil
Crystal structure of N-terminal PDZ domain of ZASP in complex with myotilin C-terminal peptide.
Descriptor: GLUTAMIC ACID, LEUCINE, LIM domain-binding protein 3
Authors:Grishkovskaya, I, Onipe, A, Kontaxis, G, Djinovic-Carugo, K.
Deposit date:2015-02-22
Release date:2016-06-29
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal structure of N-terminal PDZ domain of ZASP in complex with myotilin C-terminal peptide.
To Be Published
4XHV
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BU of 4xhv by Molmil
Crystal structure of Drosophila Spinophilin-PDZ and a C-terminal peptide of Neurexin
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, LP20995p, ...
Authors:Driller, J.H, Muhammad, K.G.H, Reddy, S, Rey, U, Boehme, M.A, Hollmann, C, Ramesh, N, Depner, H, Luetzkendorf, J, Matkovic, T, Bergeron, D, Quentin, C, Schmoranzer, J, Goettfert, F, Holt, M, Wahl, M.C, Hell, S.W, Walter, A, Sigrist, S.J, Loll, B.
Deposit date:2015-01-06
Release date:2015-07-01
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.23 Å)
Cite:Presynaptic spinophilin tunes neurexin signalling to control active zone architecture and function.
Nat Commun, 6, 2015
4XH7
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BU of 4xh7 by Molmil
Crystal structure of MUPP1 PDZ4
Descriptor: IMIDAZOLE, Multiple PDZ domain protein
Authors:Liu, Z, Zhu, H, Liu, W.
Deposit date:2015-01-05
Release date:2015-03-04
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Biochemical and structural characterization of MUPP1-PDZ4 domain from Mus musculus.
Acta Biochim.Biophys.Sin., 47, 2015
2MX6
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BU of 2mx6 by Molmil
Complex structure of Dvl PDZ domain with ligand
Descriptor: (PHQ)WV peptide, Segment polarity protein dishevelled homolog DVL-1
Authors:Zhang, X, Zheng, J.J.
Deposit date:2014-12-15
Release date:2015-12-30
Method:SOLUTION NMR
Cite:Protein-ligand interaction decoded by NMR chemical shift analysis
To be Published

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