4XHV

Crystal structure of Drosophila Spinophilin-PDZ and a C-terminal peptide of Neurexin

Summary for 4XHV

• Entry DOI: 10.2210/pdb4xhv/pdb
• Related: 3EGG
• Descriptor: LP20995p, Neurexin 1, 1,2-ETHANEDIOL, ... (6 entities in total)
• Functional Keywords: spinophilin, neurexin, praesynaptic density, synapse, signaling protein
• Biological source: Drosophila melanogaster (Fruit fly); More
• Total number of polymer chains: 2
• Total formula weight: 11124.50

Authors

Driller, J.H.,Muhammad, K.G.H.,Reddy, S.,Rey, U.,Boehme, M.A.,Hollmann, C.,Ramesh, N.,Depner, H.,Luetzkendorf, J.,Matkovic, T.,Bergeron, D.,Quentin, C.,Schmoranzer, J.,Goettfert, F.,Holt, M.,Wahl, M.C.,Hell, S.W.,Walter, A.,Sigrist, S.J.,Loll, B. (deposition date: 2015-01-06, release date: 2015-07-01, Last modification date: 2024-01-10)

• Primary citation: Muhammad, K.,Reddy-Alla, S.,Driller, J.H.,Schreiner, D.,Rey, U.,Bohme, M.A.,Hollmann, C.,Ramesh, N.,Depner, H.,Lutzkendorf, J.,Matkovic, T.,Gotz, T.,Bergeron, D.D.,Schmoranzer, J.,Goettfert, F.,Holt, M.,Wahl, M.C.,Hell, S.W.,Scheiffele, P.,Walter, A.M.,Loll, B.,Sigrist, S.J.; Presynaptic spinophilin tunes neurexin signalling to control active zone architecture and function.; Nat Commun, 6:8362-8362, 2015; PubMed: 26471740; DOI: 10.1038/ncomms9362

Experimental method

X-RAY DIFFRACTION (1.23 Å)