5FB8
Structure of Interleukin-16 bound to the 14.1 antibody
Summary for 5FB8
Entry DOI | 10.2210/pdb5fb8/pdb |
Related | 1I16 |
Descriptor | Anti-IL-16 antibody 14.1 Fab domain Kappa Chain, Anti-IL-16 antibody 14.1 Fab domain Heavy Chain, Pro-interleukin-16, ... (7 entities in total) |
Functional Keywords | cytokine, interleukin, antibody, complex, immune system |
Biological source | Mus musculus (House Mouse) More |
Cellular location | Interleukin-16: Secreted. Isoform 1: Cytoplasm . Isoform 3: Cytoplasm: Q14005 |
Total number of polymer chains | 3 |
Total formula weight | 59630.57 |
Authors | Hall, G.,Cowan, R.,Bayliss, R.,Carr, M. (deposition date: 2015-12-14, release date: 2016-06-08, Last modification date: 2024-01-10) |
Primary citation | Hall, G.,Cullen, E.,Sawmynaden, K.,Arnold, J.,Fox, S.,Cowan, R.,Muskett, F.W.,Matthews, D.,Merritt, A.,Kettleborough, C.,Cruikshank, W.,Taylor, D.,Bayliss, R.,Carr, M.D. Structure of a Potential Therapeutic Antibody Bound to Interleukin-16 (IL-16): MECHANISTIC INSIGHTS AND NEW THERAPEUTIC OPPORTUNITIES. J.Biol.Chem., 291:16840-16848, 2016 Cited by PubMed: 27231345DOI: 10.1074/jbc.M115.709303 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.07 Å) |
Structure validation
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