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6XPR
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BU of 6xpr by Molmil
Human antibody D2 H1-1/H3-1 H3 in complex with the influenza hemagglutinin head domain of A/Texas/50/2012(H3N2)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
Authors:McCarthy, K.R, Harrison, S.C, Lee, J.
Deposit date:2020-07-08
Release date:2021-05-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (4.092 Å)
Cite:A Prevalent Focused Human Antibody Response to the Influenza Virus Hemagglutinin Head Interface.
Mbio, 12, 2021
6XPO
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BU of 6xpo by Molmil
Influenza hemagglutinin A/Bangkok/01/1979(H3N2)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
Authors:McCarthy, K.R, Harrison, S.C.
Deposit date:2020-07-08
Release date:2021-05-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3 Å)
Cite:A Prevalent Focused Human Antibody Response to the Influenza Virus Hemagglutinin Head Interface.
Mbio, 12, 2021
6XGC
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BU of 6xgc by Molmil
CryoEM structure of influenza hemagglutinin A/Michigan/45/2015 in complex with cyno antibody 1C4
Descriptor: 1C4 Fab heavy chain, 1C4 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Qiu, Y, Zhou, Y.
Deposit date:2020-06-17
Release date:2021-03-10
Last modified:2021-03-17
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Broad neutralization of H1 and H3 viruses by adjuvanted influenza HA stem vaccines in nonhuman primates.
Sci Transl Med, 13, 2021
6Z2T
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BU of 6z2t by Molmil
Three-dimensional structure of an influenza hemagglutinin LAH protein in its post-fusion conformation
Descriptor: Hemagglutinin, PHOSPHATE ION
Authors:Kirsteina, A, Kazaks, A, Tars, K.
Deposit date:2020-05-18
Release date:2021-06-02
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.34 Å)
Cite:Three-dimensional structure of an influenza hemagglutinin LAH protein
To Be Published
6WZT
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BU of 6wzt by Molmil
CryoEM structure of influenza hemagglutinin A/Victoria/361/2011 in complex with cyno antibody 3B10
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cyno antibody heavy chain, ...
Authors:Qiu, Y, Zhou, Y, Darricarrere, N.
Deposit date:2020-05-14
Release date:2021-03-10
Last modified:2021-03-17
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Broad neutralization of H1 and H3 viruses by adjuvanted influenza HA stem vaccines in nonhuman primates.
Sci Transl Med, 13, 2021
6WXL
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BU of 6wxl by Molmil
Cryo-EM structure of the VRC315 clinical trial, vaccine-elicited, human antibody 1D12 in complex with an H7 SH13 HA trimer
Descriptor: 1D12 Light chain, 1D21 Heavy chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Gorman, J, Kwong, P.D.
Deposit date:2020-05-11
Release date:2021-06-09
Last modified:2022-06-22
Method:ELECTRON MICROSCOPY (2.76 Å)
Cite:Structure of an influenza group 2-neutralizing antibody targeting the hemagglutinin stem supersite.
Structure, 2022
6WXB
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BU of 6wxb by Molmil
Cryo-EM Structure of Influenza Hemagglutinin (HA) Trimer Vitrified Using Back-it-up
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, beta-D-mannopyranose
Authors:Tan, Y.Z, Rubinstein, J.L.
Deposit date:2020-05-10
Release date:2020-05-20
Last modified:2020-11-18
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Through-grid wicking enables high-speed cryoEM specimen preparation.
Acta Crystallogr D Struct Biol, 76, 2020
6WJ1
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BU of 6wj1 by Molmil
Crystal structure of Fab 54-4H03 bound to H1 influenza hemagglutinin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab 54-4H03 heavy chain, ...
Authors:Wu, N.C, Wilson, I.A.
Deposit date:2020-04-11
Release date:2020-07-01
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.503 Å)
Cite:Convergent Evolution in Breadth of Two VH6-1-Encoded Influenza Antibody Clonotypes from a Single Donor.
Cell Host Microbe, 28, 2020
6WIZ
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BU of 6wiz by Molmil
Crystal structure of Fab 54-1G05 bound to H1 influenza hemagglutinin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab 54-1G05 heavy chain, Fab 54-1G05 light chain, ...
Authors:Wu, N.C, Wilson, I.A.
Deposit date:2020-04-11
Release date:2020-07-01
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (4.2 Å)
Cite:Convergent Evolution in Breadth of Two VH6-1-Encoded Influenza Antibody Clonotypes from a Single Donor.
Cell Host Microbe, 28, 2020
6WHK
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BU of 6whk by Molmil
Minimally mutated anti-influenza broadly neutralizing antibody
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Fab Heavy Chain, ...
Authors:Bajic, G, Schmidt, A.G.
Deposit date:2020-04-08
Release date:2021-04-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Minimally mutated anti-influenza broadly neutralizing antibody
To Be Published
6WEX
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BU of 6wex by Molmil
Crystal Structure of Broadly Neutralizing Antibody 3I14-D93N Mutant Bound to the Influenza A H6 Hemagglutinin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, Hemagglutinin HA2 chain, ...
Authors:Harshbarger, W.D, Lockbaum, G.J, Deming, D.T, Attatippaholkun, N, Schiffer, C.A, Marasco, W.A.
Deposit date:2020-04-03
Release date:2020-11-25
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.49 Å)
Cite:Unique structural solution from a V H 3-30 antibody targeting the hemagglutinin stem of influenza A viruses.
Nat Commun, 12, 2021
6WEZ
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BU of 6wez by Molmil
Crystal Structure of Broadly Neutralizing Antibody 3I14-D93N Mutant Bound to the Influenza A H3 Hemagglutinin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Hemagglutinin, ...
Authors:Harshbarger, W.D, Lockbaum, G.J, Deming, D.T, Attatippaholkun, N, Schiffer, C.A, Marasco, W.A.
Deposit date:2020-04-03
Release date:2020-11-25
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.21 Å)
Cite:Unique structural solution from a V H 3-30 antibody targeting the hemagglutinin stem of influenza A viruses.
Nat Commun, 12, 2021
6WF0
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BU of 6wf0 by Molmil
Crystal Structure of Broadly Neutralizing Antibody 3I14 Bound to the Influenza A H3 Hemagglutinin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Harshbarger, W.D, Lockbaum, G.J, Deming, D.T, Attatippaholkun, N, Schiffer, C.A, Marasco, W.A.
Deposit date:2020-04-03
Release date:2020-11-25
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.46 Å)
Cite:Unique structural solution from a V H 3-30 antibody targeting the hemagglutinin stem of influenza A viruses.
Nat Commun, 12, 2021
6WF1
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BU of 6wf1 by Molmil
Crystal Structure of Broadly Neutralizing Antibody 3I14 Bound to the Influenza A H10 Hemagglutinin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, Hemagglutinin HA2 chain, ...
Authors:Harshbarger, W.D, Lockbaum, G.J, Deming, D.T, Attatippaholkun, N, Schiffer, C.A, Marasco, W.A.
Deposit date:2020-04-03
Release date:2020-11-25
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (4.19 Å)
Cite:Unique structural solution from a V H 3-30 antibody targeting the hemagglutinin stem of influenza A viruses.
Nat Commun, 12, 2021
6WCR
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BU of 6wcr by Molmil
Crystal structure of the A/Puerto Rico/8/1934 (H1N1) influenza virus hemagglutinin in complex with small molecule F0045(S)
Descriptor: (2,4-dichlorophenyl)[(2S)-2-phenylmorpholin-4-yl]methanone, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:kadam, R.U, Wilson, I.A.
Deposit date:2020-03-31
Release date:2020-08-05
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:An influenza A hemagglutinin small-molecule fusion inhibitor identified by a new high-throughput fluorescence polarization screen.
Proc.Natl.Acad.Sci.USA, 117, 2020
6Y5K
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BU of 6y5k by Molmil
Extended Intermediate form of X-31 Influenza Haemagglutinin at pH 5 (State IV)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, X-31 Influenza Haemagglutinin HA1, X-31 Influenza Haemagglutinin HA2
Authors:Benton, D.J, Rosenthal, P.B.
Deposit date:2020-02-25
Release date:2020-06-10
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structural transitions in influenza haemagglutinin at membrane fusion pH.
Nature, 583, 2020
6Y5H
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BU of 6y5h by Molmil
Ectodomain of X-31 Haemagglutinin at pH 5 (State I)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, X-31 Influenza Haemagglutinin HA1, ...
Authors:Benton, D.J, Rosenthal, P.B.
Deposit date:2020-02-25
Release date:2020-06-10
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural transitions in influenza haemagglutinin at membrane fusion pH.
Nature, 583, 2020
6Y5I
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BU of 6y5i by Molmil
Dilated form 1 of X-31 Influenza Haemagglutinin at pH 5 (State II)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, X-31 Influenza Haemagglutinin HA1, ...
Authors:Benton, D.J, Rosenthal, P.B.
Deposit date:2020-02-25
Release date:2020-06-10
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (5.5 Å)
Cite:Structural transitions in influenza haemagglutinin at membrane fusion pH.
Nature, 583, 2020
6Y5G
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BU of 6y5g by Molmil
Ectodomain of X-31 Haemagglutinin at pH 8
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, X-31 Influenza Haemagglutinin HA1, ...
Authors:Benton, D.J, Rosenthal, P.B.
Deposit date:2020-02-25
Release date:2020-06-10
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural transitions in influenza haemagglutinin at membrane fusion pH.
Nature, 583, 2020
6Y5L
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BU of 6y5l by Molmil
Signal Subtracted Extended Intermediate form of X-31 Influenza Haemagglutinin at pH 5 (State IV)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, X-31 Influenza Haemagglutinin HA1,X-31 Influenza Haemagglutinin HA1, X-31 Influenza Haemagglutinin HA2
Authors:Benton, D.J, Rosenthal, P.B.
Deposit date:2020-02-25
Release date:2020-06-10
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural transitions in influenza haemagglutinin at membrane fusion pH.
Nature, 583, 2020
6Y5J
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BU of 6y5j by Molmil
Dilated form 2 of X-31 Influenza Haemagglutinin at pH 5 (State III)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, X-31 Influenza Haemagglutinin HA1, ...
Authors:Benton, D.J, Rosenthal, P.B.
Deposit date:2020-02-25
Release date:2020-06-10
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (5.6 Å)
Cite:Structural transitions in influenza haemagglutinin at membrane fusion pH.
Nature, 583, 2020
6VMZ
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BU of 6vmz by Molmil
Crystal Structure of a H5N1 influenza virus hemagglutinin with CBS1117
Descriptor: 2,6-dichloro-N-[1-(propan-2-yl)piperidin-4-yl]benzamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin
Authors:Antanasijevic, A, Durst, M.A, Lavie, A, Caffrey, M.
Deposit date:2020-01-28
Release date:2020-07-01
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of avian influenza hemagglutinin in complex with a small molecule entry inhibitor.
Life Sci Alliance, 3, 2020
6TY1
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BU of 6ty1 by Molmil
Crystal structure of the haemagglutinin mutant (Gln226Leu, Gly228Ser) from an H10N7 seal influenza virus isolated in Germany in complex with human receptor analogue 6'-SLN
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, Hemagglutinin HA2, ...
Authors:Zhang, J, Xiong, X, Purkiss, A, Walker, P, Gamblin, S, Skehel, J.J.
Deposit date:2020-01-15
Release date:2020-10-21
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Hemagglutinin Traits Determine Transmission of Avian A/H10N7 Influenza Virus between Mammals.
Cell Host Microbe, 28, 2020
6TXO
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BU of 6txo by Molmil
Crystal structure of the haemagglutinin mutant (Gln226Leu, Del228) from an H10N7 seal influenza virus isolated in Germany in complex with avian receptor analogue 3'-SLN
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Zhang, J, Xiong, X, Purkiss, A, Walker, P, Gamblin, S, Skehel, J.J.
Deposit date:2020-01-14
Release date:2020-10-21
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Hemagglutinin Traits Determine Transmission of Avian A/H10N7 Influenza Virus between Mammals.
Cell Host Microbe, 28, 2020
6TWI
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BU of 6twi by Molmil
Crystal structure of the haemagglutinin mutant (Gln226Leu, Gly228Ser) from an H10N7 seal influenza virus isolated in Germany in complex with avian receptor analogue 3'-SLN
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Zhang, J, Xiong, X, Purkiss, A, Walker, P, Gamblin, S, Skehel, J.J.
Deposit date:2020-01-13
Release date:2020-10-21
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Hemagglutinin Traits Determine Transmission of Avian A/H10N7 Influenza Virus between Mammals.
Cell Host Microbe, 28, 2020

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