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8V7O
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BU of 8v7o by Molmil
Fab fragment of human mAb #58 in complex with computationally optimized broadly reactive H1 influenza hemagglutinin X6
Descriptor: #58 heavy chain, #58 light chain, Hemagglutinin
Authors:Nagashima, K.A, Mousa, J.J.
Deposit date:2023-12-04
Release date:2024-04-10
Method:ELECTRON MICROSCOPY (3.57 Å)
Cite:Structural basis for the broad antigenicity of the computationally optimized influenza hemagglutinin X6
To Be Published
1EO8
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BU of 1eo8 by Molmil
INFLUENZA VIRUS HEMAGGLUTININ COMPLEXED WITH A NEUTRALIZING ANTIBODY
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIBODY (HEAVY CHAIN), ...
Authors:Fleury, D, Gigant, B, Daniels, R.S, Skehel, J.J, Knossow, M, Bizebard, T.
Deposit date:2000-03-22
Release date:2000-04-12
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural evidence for recognition of a single epitope by two distinct antibodies.
Proteins, 40, 2000
7QA4
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BU of 7qa4 by Molmil
Crystal structure of stabilized H3N2 A/Hong Kong/1/1968 Hemagglutinin at 2.2 Angstrom
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
Authors:Milder, F.J, Langedijk, J.P.M.
Deposit date:2021-11-16
Release date:2022-02-02
Last modified:2022-03-30
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Universal stabilization of the influenza hemagglutinin by structure-based redesign of the pH switch regions.
Proc.Natl.Acad.Sci.USA, 119, 2022
2FK0
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BU of 2fk0 by Molmil
Crystal Structure of a H5N1 influenza virus hemagglutinin.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, hemagglutinin
Authors:Stevens, J, Wilson, I.A.
Deposit date:2006-01-03
Release date:2006-05-02
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Structure and Receptor Specificity of the Hemagglutinin from an H5N1 Influenza Virus.
Science, 312, 2006
2HMG
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BU of 2hmg by Molmil
REFINEMENT OF THE INFLUENZA VIRUS HEMAGGLUTININ BY SIMULATED ANNEALING
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, HEMAGGLUTININ (HA1 CHAIN), HEMAGGLUTININ (HA2 CHAIN), ...
Authors:Weis, W.I, Bruenger, A.T, Skehel, J.J, Wiley, D.C.
Deposit date:1989-09-11
Release date:1991-01-15
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3 Å)
Cite:Refinement of the influenza virus hemagglutinin by simulated annealing.
J.Mol.Biol., 212, 1990
2IBX
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BU of 2ibx by Molmil
Influenza virus (VN1194) H5 HA
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin
Authors:Yamada, S, Russell, R.J, Gamblin, S.J, Skehel, J.J, Kawaoka, Y.
Deposit date:2006-09-12
Release date:2006-11-28
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Haemagglutinin mutations responsible for the binding of H5N1 influenza A viruses to human-type receptors.
Nature, 444, 2006
6Z2T
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BU of 6z2t by Molmil
Three-dimensional structure of an influenza hemagglutinin LAH protein in its post-fusion conformation
Descriptor: Hemagglutinin, PHOSPHATE ION
Authors:Kirsteina, A, Kazaks, A, Tars, K.
Deposit date:2020-05-18
Release date:2021-06-02
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.34 Å)
Cite:Three-dimensional structure of an influenza hemagglutinin LAH protein
To Be Published
7A9D
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BU of 7a9d by Molmil
Crystal structure of H12 Haemagglutinin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin
Authors:Xiong, X, Walker, P, Zhang, J, Gamblin, S, Skehel, J.J.
Deposit date:2020-09-01
Release date:2020-12-02
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Hemagglutinin Structure and Activities.
Cold Spring Harb Perspect Med, 11, 2021
6ZRK
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BU of 6zrk by Molmil
Crystal structure of H8 haemagglutinin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
Authors:Xiong, X, Walker, P, Zhang, J, Gamblin, S, Skehel, J.J.
Deposit date:2020-07-13
Release date:2020-12-02
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2 Å)
Cite:Hemagglutinin Structure and Activities.
Cold Spring Harb Perspect Med, 11, 2021
8DIM
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BU of 8dim by Molmil
CryoEM structure of Influenza A virus A/Ohio/09/2015 hemagglutinin bound to CR6261 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CR6261 Fab heavy chain, CR6261 Fab light chain, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2022-06-29
Release date:2022-11-16
Method:ELECTRON MICROSCOPY (2.62 Å)
Cite:CryoEM structure of Influenza A virus A/Ohio/09/2015 hemagglutinin bound to CR6261 Fab
To Be Published
8DIU
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BU of 8diu by Molmil
Cryo-EM structure of influenza A virus A/Bayern/7/1995 hemagglutinin bound to CR6261 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CR6261 Fab heavy chain, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2022-06-29
Release date:2022-12-14
Method:ELECTRON MICROSCOPY (2.61 Å)
Cite:CryoEM structure of influenza A virus A/Bayern/7/1995 hemagglutinin bound to CR6261 Fab
To be published
8D21
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BU of 8d21 by Molmil
Cryo-EM structure of the VRC321 clinical trial, vaccine-elicited, human antibody 1B06 in complex with a stabilized NC99 HA trimer
Descriptor: 1B06 Heavy Chain, 1B06 Light Chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Gorman, J, Kwong, P.D.
Deposit date:2022-05-27
Release date:2023-04-12
Last modified:2023-05-03
Method:ELECTRON MICROSCOPY (3.96 Å)
Cite:An influenza H1 hemagglutinin stem-only immunogen elicits a broadly cross-reactive B cell response in humans.
Sci Transl Med, 15, 2023
8DIS
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BU of 8dis by Molmil
CryoEM structure of Influenza A virus A/Melbourne/1/1946 (H1N1) hemagglutinin bound to CR6261 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CR6261 Fab heavy chain, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2022-06-29
Release date:2023-06-07
Method:ELECTRON MICROSCOPY (2.62 Å)
Cite:CryoEM structure of Influenza A virus A/Melbourne/1/1946 (H1N1) hemagglutinin bound to CR6261 Fab
To be published
8F38
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BU of 8f38 by Molmil
Cryo-EM structure of X6 COBRA (H1N1) hemagglutinin bound to CR6261 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CR6261 Fab heavy chain, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2022-11-09
Release date:2023-12-13
Method:ELECTRON MICROSCOPY (2.64 Å)
Cite:Cryo-EM structure of X6 COBRA (H1N1) hemagglutinin bound to CR6261 Fab
To be published
5GJT
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BU of 5gjt by Molmil
Crystal structure of H1 hemagglutinin from A/Washington/05/2011 in complex with a neutralizing antibody 3E1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, heavy chain of human neutralizing antibody 3E1, ...
Authors:Wang, W, Zhang, T, Ding, J.
Deposit date:2016-07-01
Release date:2016-12-07
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Human antibody 3E1 targets the HA stem region of H1N1 and H5N6 influenza A viruses
Nat Commun, 7, 2016
5GJS
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BU of 5gjs by Molmil
Crystal structure of H1 hemagglutinin from A/California/04/2009 in complex with a neutralizing antibody 3E1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
Authors:Wang, W, Zhang, T, Ding, J.
Deposit date:2016-07-01
Release date:2016-12-07
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Human antibody 3E1 targets the HA stem region of H1N1 and H5N6 influenza A viruses
Nat Commun, 7, 2016
5HU8
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BU of 5hu8 by Molmil
The crystal structure of hemagglutinin from A/Sichuan/26221/2014 (H5N6) influenza virus
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Yang, H, Carney, P.J, Guo, Z, Chang, J.C, Stevens, J.
Deposit date:2016-01-27
Release date:2016-04-13
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Molecular Characterizations of Surface Proteins Hemagglutinin and Neuraminidase from Recent H5Nx Avian Influenza Viruses.
J.Virol., 90, 2016
5HUF
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BU of 5huf by Molmil
The crystal structure of hemagglutinin from A/gyrfalcon/Washington/41088-6/2014 influenza virus
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Yang, H, Carney, P.J, Guo, Z, Chang, J.C, Stevens, J.
Deposit date:2016-01-27
Release date:2016-04-13
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Molecular Characterizations of Surface Proteins Hemagglutinin and Neuraminidase from Recent H5Nx Avian Influenza Viruses.
J.Virol., 90, 2016
5HMG
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BU of 5hmg by Molmil
REFINEMENT OF THE INFLUENZA VIRUS HEMAGGLUTININ BY SIMULATED ANNEALING
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain, ...
Authors:Weis, W.I, Bruenger, A.T, Skehel, J.J, Wiley, D.C.
Deposit date:1989-09-11
Release date:1991-01-15
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Refinement of the influenza virus hemagglutinin by simulated annealing.
J.Mol.Biol., 212, 1990
5IBL
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BU of 5ibl by Molmil
Human antibody 6639 in complex with influenza hemagglutinin H1 X-181
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 6639 Heavy Chain, 6639 Light Chain, ...
Authors:Raymond, D.D, Harrison, S.C.
Deposit date:2016-02-22
Release date:2016-11-09
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.39 Å)
Cite:Influenza immunization elicits antibodies specific for an egg-adapted vaccine strain.
Nat. Med., 22, 2016
7KQH
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BU of 7kqh by Molmil
Antibodies that engage the hemagglutinin receptor-binding site of influenza B viruses
Descriptor: 2365 Fab heavy chain, 2365 Fab light chain, Hemagglutinin, ...
Authors:Bajic, G, Harrison, S.C.
Deposit date:2020-11-16
Release date:2020-12-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Antibodies That Engage the Hemagglutinin Receptor-Binding Site of Influenza B Viruses.
Acs Infect Dis., 7, 2021
7KQI
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BU of 7kqi by Molmil
Antibodies that engage the hemagglutinin receptor-binding site of influenza B viruses
Descriptor: 1209 Fab heavy chain, 1209 Fab light chain, Hemagglutinin, ...
Authors:Bajic, G, Harrison, S.C.
Deposit date:2020-11-16
Release date:2020-12-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (4.2 Å)
Cite:Antibodies That Engage the Hemagglutinin Receptor-Binding Site of Influenza B Viruses.
Acs Infect Dis., 7, 2021
7KQG
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BU of 7kqg by Molmil
Antibodies that engage the hemagglutinin receptor-binding site of influenza B viruses
Descriptor: 1272 Fab heavy chain, 1272 Fab light chain, Hemagglutinin, ...
Authors:Bajic, G, Harrison, S.C.
Deposit date:2020-11-16
Release date:2020-12-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Antibodies That Engage the Hemagglutinin Receptor-Binding Site of Influenza B Viruses.
Acs Infect Dis., 7, 2021
7KNA
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BU of 7kna by Molmil
Localized reconstruction of the H1 A/Michigan/45/2015 ectodomain displayed at the surface of I53_dn5 nanoparticle
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin,I53_dn5
Authors:Acton, O.J, Park, Y.J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2020-11-04
Release date:2021-03-31
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Quadrivalent influenza nanoparticle vaccines induce broad protection.
Nature, 592, 2021
7L0L
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BU of 7l0l by Molmil
Cryo-EM structure of the VRC316 clinical trial, vaccine-elicited, human antibody 316-310-1B11 in complex with an H2 CAN05 HA trimer
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 316-310-1B11 Heavy Chain, 316-310-1B11 Light Chain, ...
Authors:Gorman, J, Kwong, P.D.
Deposit date:2020-12-11
Release date:2021-11-03
Last modified:2022-03-09
Method:ELECTRON MICROSCOPY (2.85 Å)
Cite:A single residue in influenza virus H2 hemagglutinin enhances the breadth of the B cell response elicited by H2 vaccination.
Nat Med, 28, 2022

219869

數據於2024-05-15公開中

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