7QA4

Crystal structure of stabilized H3N2 A/Hong Kong/1/1968 Hemagglutinin at 2.2 Angstrom

Summary for 7QA4

Entry DOI	10.2210/pdb7qa4/pdb
Descriptor	Hemagglutinin, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
Functional Keywords	influenza, hemagglutinin, stabilized, fusion protein, unknown function, viral protein
Biological source	Influenza A virus (strain A/Hong Kong/1/1968 H3N2)
Total number of polymer chains	1
Total formula weight	59761.06
Authors	Milder, F.J.,Langedijk, J.P.M. (deposition date: 2021-11-16, release date: 2022-02-02, Last modification date: 2022-03-30)
Primary citation	Milder, F.J.,Jongeneelen, M.,Ritschel, T.,Bouchier, P.,Bisschop, I.J.M.,de Man, M.,Veldman, D.,Le, L.,Kaufmann, B.,Bakkers, M.J.G.,Juraszek, J.,Brandenburg, B.,Langedijk, J.P.M. Universal stabilization of the influenza hemagglutinin by structure-based redesign of the pH switch regions. Proc.Natl.Acad.Sci.USA, 119:-, 2022 Cited by PubMed: 35131851 DOI: 10.1073/pnas.2115379119 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.19 Å)

Structure validation