2VIR
| INFLUENZA VIRUS HEMAGGLUTININ COMPLEXED WITH A NEUTRALIZING ANTIBODY | Descriptor: | HEMAGGLUTININ, IMMUNOGLOBULIN (IGG1, LAMBDA), ... | Authors: | Bizebard, T, Fleury, D, Gigant, B, Wharton, S.A, Skehel, J.J, Knossow, M. | Deposit date: | 1997-12-22 | Release date: | 1998-04-29 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (3.25 Å) | Cite: | Antigen distortion allows influenza virus to escape neutralization. Nat.Struct.Biol., 5, 1998
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1Z2B
| Tubulin-colchicine-vinblastine: stathmin-like domain complex | Descriptor: | (2ALPHA,2'BETA,3BETA,4ALPHA,5BETA)-VINCALEUKOBLASTINE, 2-MERCAPTO-N-[1,2,3,10-TETRAMETHOXY-9-OXO-5,6,7,9-TETRAHYDRO-BENZO[A]HEPTALEN-7-YL]ACETAMIDE, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Gigant, B, Wang, C, Ravelli, R.B.G, Roussi, F, Steinmetz, M.O, Curmi, P.A, Sobel, A, Knossow, M. | Deposit date: | 2005-03-08 | Release date: | 2005-05-31 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (4.1 Å) | Cite: | Structural basis for the regulation of tubulin by vinblastine. Nature, 435, 2005
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2VIU
| INFLUENZA VIRUS HEMAGGLUTININ | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, HEMAGGLUTININ, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Bizebard, T, Fleury, D, Gigant, B, Wharton, S.A, Skehel, J.J, Knossow, M. | Deposit date: | 1997-12-22 | Release date: | 1998-04-29 | Last modified: | 2021-11-03 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Antigen distortion allows influenza virus to escape neutralization. Nat.Struct.Biol., 5, 1998
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4Y05
| KIF2C short Loop2 construct | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Kinesin-like protein KIF2C, MAGNESIUM ION, ... | Authors: | Wang, W, Knossow, M, Gigant, B. | Deposit date: | 2015-02-05 | Release date: | 2015-06-17 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.59 Å) | Cite: | New Insights into the Coupling between Microtubule Depolymerization and ATP Hydrolysis by Kinesin-13 Protein Kif2C. J.Biol.Chem., 290, 2015
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2VIS
| INFLUENZA VIRUS HEMAGGLUTININ, (ESCAPE) MUTANT WITH THR 131 REPLACED BY ILE, COMPLEXED WITH A NEUTRALIZING ANTIBODY | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, HEMAGGLUTININ, IMMUNOGLOBULIN (IGG1, ... | Authors: | Bizebard, T, Fleury, D, Gigant, B, Wharton, S.A, Skehel, J.J, Knossow, M. | Deposit date: | 1997-12-22 | Release date: | 1998-04-29 | Last modified: | 2021-11-03 | Method: | X-RAY DIFFRACTION (3.25 Å) | Cite: | Antigen distortion allows influenza virus to escape neutralization. Nat.Struct.Biol., 5, 1998
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2VIT
| INFLUENZA VIRUS HEMAGGLUTININ, MUTANT WITH THR 155 REPLACED BY ILE, COMPLEXED WITH A NEUTRALIZING ANTIBODY | Descriptor: | HEMAGGLUTININ, IMMUNOGLOBULIN (IGG1, LAMBDA), ... | Authors: | Bizebard, T, Fleury, D, Gigant, B, Wharton, S.A, Skehel, J.J, Knossow, M. | Deposit date: | 1997-12-22 | Release date: | 1998-04-29 | Last modified: | 2021-11-03 | Method: | X-RAY DIFFRACTION (3.25 Å) | Cite: | Antigen distortion allows influenza virus to escape neutralization. Nat.Struct.Biol., 5, 1998
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1QFU
| INFLUENZA VIRUS HEMAGGLUTININ COMPLEXED WITH A NEUTRALIZING ANTIBODY | Descriptor: | 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, PROTEIN (HEMAGGLUTININ (HA1 CHAIN)), ... | Authors: | Fleury, D, Gigant, B, Bizebard, T, Daniels, R.S, Skehel, J.J, Knossow, M. | Deposit date: | 1999-04-14 | Release date: | 1999-04-16 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | A complex of influenza hemagglutinin with a neutralizing antibody that binds outside the virus receptor binding site. Nat.Struct.Biol., 6, 1999
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2GFB
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3DU7
| Tubulin-colchicine-phomopsin A: Stathmin-like domain complex | Descriptor: | 2-MERCAPTO-N-[1,2,3,10-TETRAMETHOXY-9-OXO-5,6,7,9-TETRAHYDRO-BENZO[A]HEPTALEN-7-YL]ACETAMIDE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Cormier, A, Marchand, M, Ravelli, R.B, Knossow, M, Gigant, B. | Deposit date: | 2008-07-17 | Release date: | 2008-10-21 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (4.1 Å) | Cite: | Structural insight into the inhibition of tubulin by vinca domain peptide ligands Embo Rep., 9, 2008
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5EYP
| TUBULIN-DARPIN COMPLEX | Descriptor: | DESIGNED ANKYRIN REPEAT PROTEIN (DARPIN), GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Ahmad, S, Knossow, M, Gigant, B. | Deposit date: | 2015-11-25 | Release date: | 2016-07-20 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Destabilizing an interacting motif strengthens the association of a designed ankyrin repeat protein with tubulin. Sci Rep, 6, 2016
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3E22
| Tubulin-colchicine-soblidotin: Stathmin-like domain complex | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Cormier, A, Marchand, M, Ravelli, R.B, Knossow, M, Gigant, B. | Deposit date: | 2008-08-05 | Release date: | 2008-10-21 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.8 Å) | Cite: | Structural insight into the inhibition of tubulin by vinca domain peptide ligands Embo Rep., 9, 2008
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3N2K
| TUBULIN-NSC 613862: RB3 Stathmin-like domain complex | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Barbier, P, Dorleans, A, Devred, F, Sanz, L, Allegro, D, Alfonso, C, Knossow, M, Peyrot, V, Andreu, J.M. | Deposit date: | 2010-05-18 | Release date: | 2010-07-28 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (4 Å) | Cite: | Stathmin and interfacial microtubule inhibitors recognize a naturally curved conformation of tubulin dimers. J.Biol.Chem., 285, 2010
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3N2G
| TUBULIN-NSC 613863: RB3 Stathmin-like domain complex | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Barbier, P, Dorleans, A, Devred, F, Sanz, L, Allegro, D, Alfonso, C, Knossow, M, Peyrot, V, Andreu, J.M. | Deposit date: | 2010-05-18 | Release date: | 2010-07-28 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (4 Å) | Cite: | Stathmin and interfacial microtubule inhibitors recognize a naturally curved conformation of tubulin dimers. J.Biol.Chem., 285, 2010
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4EB6
| Tubulin-Vinblastine: Stathmin-like complex | Descriptor: | (2ALPHA,2'BETA,3BETA,4ALPHA,5BETA)-VINCALEUKOBLASTINE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Ranaivoson, F.M, Gigant, B, Knossow, M. | Deposit date: | 2012-03-23 | Release date: | 2012-08-01 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.47 Å) | Cite: | Structural plasticity of tubulin assembly probed by vinca-domain ligands. Acta Crystallogr.,Sect.D, 68, 2012
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4DRX
| GTP-Tubulin in complex with a DARPIN | Descriptor: | Designed ankyrin repeat protein (DARPIN) D1, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Pecqueur, L, Gigant, B, Knossow, M. | Deposit date: | 2012-02-17 | Release date: | 2012-07-11 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.22 Å) | Cite: | A designed ankyrin repeat protein selected to bind to tubulin caps the microtubule plus end. Proc.Natl.Acad.Sci.USA, 109, 2012
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1SQK
| CRYSTAL STRUCTURE OF CIBOULOT IN COMPLEX WITH SKELETAL ACTIN | Descriptor: | ACTIN, ALPHA SKELETAL MUSCLE, ADENOSINE-5'-DIPHOSPHATE, ... | Authors: | Hertzog, M, Van Heijenoort, C, Didry, D, Gaudier, M, Gigant, B, Coutant, J, Didelot, G, Preat, T, Knossow, M, Guittet, E, Carlier, M.F. | Deposit date: | 2004-03-19 | Release date: | 2004-06-15 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The beta-Thymosin/WH2 Domain; Structural Basis for the Switch from Inhibition to Promotion of Actin Assembly Cell(Cambridge,Mass.), 117, 2004
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4LNU
| Nucleotide-free kinesin motor domain in complex with tubulin and a DARPin | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Designed ankyrin repeat protein (DARPIN) D1, GLYCEROL, ... | Authors: | Cao, L, Gigant, B, Knossow, M. | Deposit date: | 2013-07-12 | Release date: | 2014-12-03 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.19 Å) | Cite: | The structure of apo-kinesin bound to tubulin links the nucleotide cycle to movement Nat Commun, 5, 2014
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4P40
| Chlamydia pneumoniae CopN | Descriptor: | CHLORIDE ION, CopN, DIMETHYLAMINE, ... | Authors: | Nawrotek, A, Guimaraes, B.G, Knossow, M, Gigant, B. | Deposit date: | 2014-03-10 | Release date: | 2014-07-30 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Biochemical and Structural Insights into Microtubule Perturbation by CopN from Chlamydia pneumoniae. J.Biol.Chem., 289, 2014
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4F61
| Tubulin:Stathmin-like domain complex | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Gigant, B, Mignot, I, Knossow, M. | Deposit date: | 2012-05-14 | Release date: | 2012-07-18 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (4.17 Å) | Cite: | Design and characterization of modular scaffolds for tubulin assembly. J.Biol.Chem., 287, 2012
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4F6R
| Tubulin:Stathmin-like domain complex | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Designed ankyrin repeat protein (DARPIN) D2, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Gigant, B, Mignot, I, Knossow, M. | Deposit date: | 2012-05-15 | Release date: | 2012-07-18 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.64 Å) | Cite: | Design and characterization of modular scaffolds for tubulin assembly. J.Biol.Chem., 287, 2012
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1LG7
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4DUI
| DARPIN D1 binding to tubulin beta chain (not in complex) | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, DESIGNED ANKYRIN REPEAT PROTEIN (DARPIN) D1 | Authors: | Pecqueur, L, Duellberg, C, Dreier, B, Wang, Q, Jiang, C, Pluckthun, A, Surrey, T, Gigant, B, Knossow, M. | Deposit date: | 2012-02-22 | Release date: | 2013-02-27 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.16 Å) | Cite: | An Anti-Tubulin Darpin Caps the Microtubule Plus-End To be Published
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4P3Z
| Chlamydia pneumoniae CopN (D29 construct) | Descriptor: | CopN, GLYCEROL, SULFATE ION | Authors: | Nawrotek, A, Guimaraes, B.G, Knossow, M, Gigant, B. | Deposit date: | 2014-03-10 | Release date: | 2014-07-30 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Biochemical and Structural Insights into Microtubule Perturbation by CopN from Chlamydia pneumoniae. J.Biol.Chem., 289, 2014
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1SA1
| Tubulin-podophyllotoxin: stathmin-like domain complex | Descriptor: | 9-HYDROXY-5-(3,4,5-TRIMETHOXYPHENYL)-5,8,8A,9-TETRAHYDROFURO[3',4':6,7]NAPHTHO[2,3-D][1,3]DIOXOL-6(5AH)-ONE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Ravelli, R.B, Gigant, B, Curmi, P.A, Jourdain, I, Lachkar, S, Sobel, A, Knossow, M. | Deposit date: | 2004-02-06 | Release date: | 2004-03-23 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (4.2 Å) | Cite: | Insight into tubulin regulation from a complex with colchicine and a stathmin-like domain. Nature, 428, 2004
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1SA0
| TUBULIN-COLCHICINE: STATHMIN-LIKE DOMAIN COMPLEX | Descriptor: | 2-MERCAPTO-N-[1,2,3,10-TETRAMETHOXY-9-OXO-5,6,7,9-TETRAHYDRO-BENZO[A]HEPTALEN-7-YL]ACETAMIDE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Ravelli, R.B, Gigant, B, Curmi, P.A, Jourdain, I, Lachkar, S, Sobel, A, Knossow, M. | Deposit date: | 2004-02-06 | Release date: | 2004-03-23 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3.58 Å) | Cite: | Insight into tubulin regulation from a complex with colchicine and a stathmin-like domain. Nature, 428, 2004
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