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6RMB
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BU of 6rmb by Molmil
Crystal structure of the DEAH-box ATPase Prp2 in complex with Spp2 and ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Putative mRNA splicing factor, ...
Authors:Hamann, F, Neumann, P, Ficner, R.
Deposit date:2019-05-06
Release date:2020-02-05
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural analysis of the intrinsically disordered splicing factor Spp2 and its binding to the DEAH-box ATPase Prp2.
Proc.Natl.Acad.Sci.USA, 117, 2020
6RO1
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BU of 6ro1 by Molmil
X-ray crystal structure of the MTR4 NVL complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, Exosome RNA helicase MTR4, ...
Authors:Lingaraju, M, Langer, L.M, Basquin, J, Falk, S, Conti, E.
Deposit date:2019-05-10
Release date:2019-07-03
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.07 Å)
Cite:The MTR4 helicase recruits nuclear adaptors of the human RNA exosome using distinct arch-interacting motifs.
Nat Commun, 10, 2019
6RMC
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BU of 6rmc by Molmil
Crystal structure of the DEAH-box ATPase Prp2 in complex with Spp2 and ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Putative mRNA splicing factor, ...
Authors:Hamann, F, Neumann, P, Schmitt, A, Ficner, R.
Deposit date:2019-05-06
Release date:2020-02-05
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural analysis of the intrinsically disordered splicing factor Spp2 and its binding to the DEAH-box ATPase Prp2.
Proc.Natl.Acad.Sci.USA, 117, 2020
6RMA
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BU of 6rma by Molmil
Crystal structure of the DEAH-box ATPase Prp2 in complex with Spp2 and ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, GLYCEROL, ...
Authors:Hamann, F, Neumann, P, Ficner, R.
Deposit date:2019-05-06
Release date:2020-02-05
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural analysis of the intrinsically disordered splicing factor Spp2 and its binding to the DEAH-box ATPase Prp2.
Proc.Natl.Acad.Sci.USA, 117, 2020
6RM8
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BU of 6rm8 by Molmil
Crystal structure of the DEAH-box ATPase Prp2 in complex with Spp2 and ADP
Descriptor: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ...
Authors:Hamann, F, Neumann, P, Ficner, R.
Deposit date:2019-05-06
Release date:2020-02-05
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural analysis of the intrinsically disordered splicing factor Spp2 and its binding to the DEAH-box ATPase Prp2.
Proc.Natl.Acad.Sci.USA, 117, 2020
6S8Q
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BU of 6s8q by Molmil
Human Brr2 Helicase Region in complex with C-tail deleted Jab1
Descriptor: Pre-mRNA-processing-splicing factor 8, SULFATE ION, U5 small nuclear ribonucleoprotein 200 kDa helicase
Authors:Santos, K.F, Vester, K, Wahl, M.C.
Deposit date:2019-07-10
Release date:2020-01-22
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (2.391 Å)
Cite:The inactive C-terminal cassette of the dual-cassette RNA helicase BRR2 both stimulates and inhibits the activity of the N-terminal helicase unit.
J.Biol.Chem., 295, 2020
6S9I
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BU of 6s9i by Molmil
Human Brr2 Helicase Region D534C/N1866C in complex with C-tail deleted Jab1
Descriptor: Pre-mRNA-processing-splicing factor 8, U5 small nuclear ribonucleoprotein 200 kDa helicase
Authors:Vester, K, Santos, K.F, Wahl, M.C.
Deposit date:2019-07-13
Release date:2020-01-22
Last modified:2020-02-26
Method:X-RAY DIFFRACTION (2.598 Å)
Cite:The inactive C-terminal cassette of the dual-cassette RNA helicase BRR2 both stimulates and inhibits the activity of the N-terminal helicase unit.
J.Biol.Chem., 295, 2020
6SH7
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BU of 6sh7 by Molmil
Crystal structure of the human DEAH-helicase DHX15 in complex with the NKRF G-patch
Descriptor: NF-kappa-B-repressing factor, Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15
Authors:Jonas, S, Studer, M.K, Ivanovic, L.
Deposit date:2019-08-05
Release date:2020-04-22
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Structural basis for DEAH-helicase activation by G-patch proteins.
Proc.Natl.Acad.Sci.USA, 117, 2020
6SH6
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BU of 6sh6 by Molmil
Crystal structure of the human DEAH-helicase DHX15 in complex with the NKRF G-patch bound to ADP
Descriptor: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Jonas, S, Studer, M.K, Ivanovic, L.
Deposit date:2019-08-05
Release date:2020-04-22
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural basis for DEAH-helicase activation by G-patch proteins.
Proc.Natl.Acad.Sci.USA, 117, 2020
6S8O
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BU of 6s8o by Molmil
Human Brr2 Helicase Region M641C/A1582C
Descriptor: U5 small nuclear ribonucleoprotein 200 kDa helicase
Authors:Vester, K, Santos, K.F, Wahl, M.C.
Deposit date:2019-07-10
Release date:2020-01-22
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.172 Å)
Cite:The inactive C-terminal cassette of the dual-cassette RNA helicase BRR2 both stimulates and inhibits the activity of the N-terminal helicase unit.
J.Biol.Chem., 295, 2020
6UP4
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BU of 6up4 by Molmil
Crystal structure of the murine DHX36 helicase in complex with ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Dhx36 protein, MAGNESIUM ION
Authors:Liu, Z, Xiao, T.S.
Deposit date:2019-10-16
Release date:2020-04-15
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Function of Auxiliary Domains of the DEAH/RHA Helicase DHX36 in RNA Remodeling.
J.Mol.Biol., 432, 2020
6UP3
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BU of 6up3 by Molmil
Crystal structure of the murine DHX36 helicase in complex with ANP
Descriptor: Dhx36 protein, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Chuenchor, W, Jiang, J, Xiao, T.S.
Deposit date:2019-10-16
Release date:2020-10-28
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.691 Å)
Cite:Crystal structure of the murine DHX36 helicase in complex with ANP
To be published
6UV4
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BU of 6uv4 by Molmil
Crystal structure of the core domain of RNA helicase DDX17 with RNA pri-18a-oligo1
Descriptor: 18a_oligo1, ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, ...
Authors:Ngo, T.D, Partin, A.C, Nam, Y.
Deposit date:2019-11-01
Release date:2020-01-01
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:RNA Specificity and Autoregulation of DDX17, a Modulator of MicroRNA Biogenesis.
Cell Rep, 29, 2019
6UV3
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BU of 6uv3 by Molmil
Crystal structure of the core domain of RNA helicase DDX17 with RNA pri-125a-oligo2
Descriptor: 125a-oligo2, ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, ...
Authors:Ngo, T.D, Partin, A.C, Nam, Y.
Deposit date:2019-11-01
Release date:2020-01-01
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.597 Å)
Cite:RNA Specificity and Autoregulation of DDX17, a Modulator of MicroRNA Biogenesis.
Cell Rep, 29, 2019
6UV0
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BU of 6uv0 by Molmil
Crystal structure of apo core domain of RNA helicase DDX17
Descriptor: MAGNESIUM ION, Probable ATP-dependent RNA helicase DDX17
Authors:Ngo, T.D, Partin, A.C, Nam, Y.
Deposit date:2019-11-01
Release date:2020-01-01
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.601 Å)
Cite:RNA Specificity and Autoregulation of DDX17, a Modulator of MicroRNA Biogenesis.
Cell Rep, 29, 2019
6UP2
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BU of 6up2 by Molmil
Crystal structure of the murine DHX36 helicase
Descriptor: CHLORIDE ION, Dhx36 protein, GLYCEROL
Authors:Chuenchor, W, Jiang, J, Xiao, T.S.
Deposit date:2019-10-16
Release date:2020-10-28
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Crystal structure of the murine DHX36 helicase
To be published
6UV1
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BU of 6uv1 by Molmil
Crystal structure of RNA helicase DDX17 in complex of rU10 RNA
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ...
Authors:Ngo, T.D, Partin, A.C, Nam, Y.
Deposit date:2019-11-01
Release date:2020-01-01
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.307 Å)
Cite:RNA Specificity and Autoregulation of DDX17, a Modulator of MicroRNA Biogenesis.
Cell Rep, 29, 2019
6UV2
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BU of 6uv2 by Molmil
Crystal structure of the core domain of RNA helicase DDX17 with RNA pri-125a-oligo1
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ...
Authors:Ngo, T.D, Partin, A.C, Nam, Y.
Deposit date:2019-11-01
Release date:2020-01-01
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.894 Å)
Cite:RNA Specificity and Autoregulation of DDX17, a Modulator of MicroRNA Biogenesis.
Cell Rep, 29, 2019
8CNT
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BU of 8cnt by Molmil
Structure of the DEAH-box helicase Prp16 in complex with ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, HEXAETHYLENE GLYCOL, MAGNESIUM ION, ...
Authors:Garbers, T.B, Neumann, P, Ficner, R.
Deposit date:2023-02-24
Release date:2023-08-23
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of Prp16 in complex with ADP.
Acta Crystallogr.,Sect.F, 79, 2023
8DPE
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BU of 8dpe by Molmil
Crystal structure of ATP-dependent RNA helicase DDX42
Descriptor: ATP-dependent RNA helicase DDX42
Authors:Larsen, N.A, Tsai, J.
Deposit date:2022-07-15
Release date:2022-08-24
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.531 Å)
Cite:Crystal structure of ATP-dependent RNA helicase DDX42
To Be Published
8DVR
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BU of 8dvr by Molmil
Cryo-EM structure of RIG-I bound to the end of p3SLR30 (+AMPPNP)
Descriptor: Antiviral innate immune response receptor RIG-I, GUANOSINE-5'-TRIPHOSPHATE, ZINC ION, ...
Authors:Wang, W, Pyle, A.M.
Deposit date:2022-07-29
Release date:2022-11-02
Last modified:2022-11-16
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:The RIG-I receptor adopts two different conformations for distinguishing host from viral RNA ligands.
Mol.Cell, 82, 2022
8DVU
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BU of 8dvu by Molmil
Cryo-EM structure of RIG-I bound to the internal sites of OHSLR30 (+ATP)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Antiviral innate immune response receptor RIG-I, MAGNESIUM ION, ...
Authors:Wang, W, Pyle, A.M.
Deposit date:2022-07-29
Release date:2022-11-16
Last modified:2022-11-30
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:The RIG-I receptor adopts two different conformations for distinguishing host from viral RNA ligands.
Mol.Cell, 82, 2022
8DVS
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BU of 8dvs by Molmil
Cryo-EM structure of RIG-I bound to the end of OHSLR30 (+ATP)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Antiviral innate immune response receptor RIG-I, MAGNESIUM ION, ...
Authors:Wang, W, Pyle, A.M.
Deposit date:2022-07-29
Release date:2022-11-16
Last modified:2022-11-30
Method:ELECTRON MICROSCOPY (3 Å)
Cite:The RIG-I receptor adopts two different conformations for distinguishing host from viral RNA ligands.
Mol.Cell, 82, 2022
8EJM
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BU of 8ejm by Molmil
Crystal structure of human DEAH-box helicase DHX15 in complex with SUGP1 G-patch
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase DHX15, CHLORIDE ION, ...
Authors:Huang, J, Tong, L.
Deposit date:2022-09-17
Release date:2022-12-14
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:DHX15 is involved in SUGP1-mediated RNA missplicing by mutant SF3B1 in cancer.
Proc.Natl.Acad.Sci.USA, 119, 2022
8FAK
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BU of 8fak by Molmil
DNA replication fork binding triggers structural changes in the PriA DNA helicase that regulate the PriA-PriB replication restart pathway in E. coli
Descriptor: DNA (5'-D(P*CP*AP*GP*AP*CP*TP*CP*AP*TP*TP*TP*AP*GP*CP*CP*CP*TP*TP*AP*TP*CP*CP*G)-3'), DNA (5'-D(P*CP*GP*GP*AP*TP*AP*AP*GP*GP*GP*CP*TP*GP*AP*GP*CP*AP*CP*GP*CP*CP*GP*A)-3'), DNA (5'-D(P*TP*CP*GP*GP*CP*GP*TP*GP*CP*TP*C)-3'), ...
Authors:Duckworth, A.T, Ducos, P.L, McMillan, S.D, Satyshur, K.A, Blumenthal, K.H, Deorio, H.R, Larson, J.A, Sandler, S.J, Grant, T, Keck, J.L.
Deposit date:2022-11-28
Release date:2023-05-10
Last modified:2023-05-24
Method:ELECTRON MICROSCOPY (3.22 Å)
Cite:Replication fork binding triggers structural changes in the PriA helicase that govern DNA replication restart in E. coli.
Nat Commun, 14, 2023

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數據於2024-05-22公開中

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